ATE338139T1 - Herstellung von 3-hydroxypropionsäure in rekombinanten organismen - Google Patents
Herstellung von 3-hydroxypropionsäure in rekombinanten organismenInfo
- Publication number
- ATE338139T1 ATE338139T1 AT00959652T AT00959652T ATE338139T1 AT E338139 T1 ATE338139 T1 AT E338139T1 AT 00959652 T AT00959652 T AT 00959652T AT 00959652 T AT00959652 T AT 00959652T AT E338139 T1 ATE338139 T1 AT E338139T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- hydroxypropionic acid
- recombinant organisms
- bacterial host
- glycerol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/0103—Glycerol dehydratase (4.2.1.30)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15144099P | 1999-08-30 | 1999-08-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE338139T1 true ATE338139T1 (de) | 2006-09-15 |
Family
ID=22538777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00959652T ATE338139T1 (de) | 1999-08-30 | 2000-08-30 | Herstellung von 3-hydroxypropionsäure in rekombinanten organismen |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1124979B1 (de) |
| AT (1) | ATE338139T1 (de) |
| AU (1) | AU7093600A (de) |
| BR (1) | BR0008355A (de) |
| DE (1) | DE60030403D1 (de) |
| WO (1) | WO2001016346A1 (de) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7186541B2 (en) | 2000-11-20 | 2007-03-06 | Cargill, Incorporated | 3-hydroxypropionic acid and other organic compounds |
| EP1575881B1 (de) | 2002-01-18 | 2009-05-27 | Novozymes A/S | Alanin-2,3-aminomutase |
| AU2003207708A1 (en) * | 2002-02-20 | 2003-09-09 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of map kinase genes |
| ATE413456T1 (de) * | 2002-03-13 | 2008-11-15 | Evonik Degussa Gmbh | Verfahren zur herstellung von l-aminosäuren unter verwendung von stämmen der familie enterobacteriaceae |
| DE10210960A1 (de) * | 2002-03-13 | 2003-09-25 | Degussa | Verfahren zur fermentativen Hestellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| CN1781897A (zh) * | 2002-03-25 | 2006-06-07 | 嘉吉有限公司 | 制造β-羟基羧酸烷氧基衍生物的方法 |
| WO2005118719A2 (en) | 2003-12-04 | 2005-12-15 | Cargill, Incorporated | Production of 3-hydroxypropionic acid using beta-alanine/pyruvate aminotransferase |
| MX2007001195A (es) | 2004-07-30 | 2007-10-03 | Cargill Inc | Alanina 2,3-aminomutasas. |
| JP2008517607A (ja) | 2004-10-25 | 2008-05-29 | コデクシス, インコーポレイテッド | 改良されたアラニン2,3−アミノムターゼおよび関連ポリヌクレオチド |
| TWI529181B (zh) * | 2005-02-28 | 2016-04-11 | 贏創德固賽有限責任公司 | 以可更新原料為基之吸水聚合物結構及其生產的方法 |
| JP2007082476A (ja) * | 2005-09-22 | 2007-04-05 | Nippon Shokubai Co Ltd | グリセリンから3−ヒドロキシプロピオン酸を製造する方法 |
| DE102005048818A1 (de) | 2005-10-10 | 2007-04-12 | Degussa Ag | Mikrobiologische Herstellung von 3-Hydroxypropionsäure |
| WO2007047773A2 (en) | 2005-10-14 | 2007-04-26 | Codexis, Inc. | Alanine 2,3-aminomutases and related polynucleotides |
| DE102006039203B4 (de) | 2006-08-22 | 2014-06-18 | Evonik Degussa Gmbh | Verfahren zur Herstellung von durch Kristallisation gereinigter Acrylsäure aus Hydroxypropionsäure sowie Vorrichtung dazu |
| DE102007015583A1 (de) | 2007-03-29 | 2008-10-02 | Albert-Ludwigs-Universität Freiburg | Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung |
| US8048624B1 (en) | 2007-12-04 | 2011-11-01 | Opx Biotechnologies, Inc. | Compositions and methods for 3-hydroxypropionate bio-production from biomass |
| CN107090424A (zh) | 2008-01-22 | 2017-08-25 | 基因组股份公司 | 利用合成气或其它气态碳源和甲醇的方法和有机体 |
| EP3450550A1 (de) | 2008-03-05 | 2019-03-06 | Genomatica, Inc. | Primäre, alkohole produzierende organismen |
| WO2009135074A2 (en) | 2008-05-01 | 2009-11-05 | Genomatica, Inc. | Microorganisms for the production of methacrylic acid |
| EP2308913B1 (de) | 2008-07-30 | 2016-04-20 | Mitsui Chemicals, Inc. | Polyesterpolyol, zusammensetzung für polyurethan, zusammensetzung für polyurethanschaumstoff, polyurethanharz und polyurethanschaumstoff |
| EP3865569B1 (de) | 2009-04-30 | 2023-10-04 | Genomatica, Inc. | Organismen zur herstellung von 1,3-butandiol |
| BRPI1013505A2 (pt) | 2009-04-30 | 2018-02-14 | Genomatica Inc | organismos para a produção de isopropanol, n-butanol, e isobutanol |
| SG175379A1 (en) | 2009-05-15 | 2011-12-29 | Nippon Catalytic Chem Ind | Process for producing (meth)acrylic acid and crystallization system |
| WO2010131589A1 (ja) | 2009-05-15 | 2010-11-18 | 株式会社日本触媒 | (メタ)アクリル酸の製造方法 |
| US8586787B2 (en) | 2009-05-15 | 2013-11-19 | Nippon Shokubai Co., Ltd. | Process for producing (meth)acrylic acid |
| DK2462221T3 (en) | 2009-08-05 | 2017-05-22 | Genomatica Inc | SEMISYNTHETIC TEREPHTHALIC ACID BY MICRO-ORGANISMS PRODUCING MUCONIC ACID |
| CA2775390C (en) | 2009-09-27 | 2021-06-29 | Opx Biotechnologies, Inc. | Method for producing 3-hydroxypropionic acid and other products |
| US8809027B1 (en) | 2009-09-27 | 2014-08-19 | Opx Biotechnologies, Inc. | Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase |
| US20110097767A1 (en) | 2009-10-23 | 2011-04-28 | Priti Pharkya | Microorganisms for the production of aniline |
| CN102933715B (zh) * | 2009-10-29 | 2015-04-29 | 韩国生命工学研究院 | 从甘油生产3-羟基丙酸的方法 |
| CN102834508A (zh) | 2010-01-29 | 2012-12-19 | 基因组股份公司 | 用于生物合成对甲苯甲酸和对苯二甲酸的微生物和方法 |
| US9023636B2 (en) | 2010-04-30 | 2015-05-05 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of propylene |
| EP2588598B1 (de) | 2010-07-02 | 2016-03-09 | Metabolic Explorer | Verfahren zur herstellung von hydroxysäuren |
| WO2012018624A2 (en) | 2010-07-26 | 2012-02-09 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene |
| US10138504B2 (en) | 2010-08-06 | 2018-11-27 | Lallemand Hungary Liquidity Management Llc | Production of malonyl-CoA derived products via anaerobic pathways |
| AU2011336923B2 (en) | 2010-11-22 | 2017-02-16 | Cargill, Incorporated | Compositions and methods for 3-hydroxypropionic acid production |
| EP2660235A4 (de) | 2010-12-28 | 2016-01-20 | Nippon Catalytic Chem Ind | Verfahren zur herstellung von acrylsäure und/oder einem ester davon und polymer aus der acrylsäure und/oder dem ester davon |
| BR112014007647A2 (pt) | 2011-09-30 | 2017-04-18 | Novozymes As | “variante de 3-hpdh, polipeptídeo tendo atividade de 3-hpdh, polinucleotídeo isolado, célula hospedeira microbiana transgênica, e, método para produzir 3-hp |
| WO2013085321A1 (ko) * | 2011-12-07 | 2013-06-13 | 삼성전자주식회사 | 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산을 생산하는 재조합 미생물 및 이를 이용한 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산의 생산방법 |
| KR101494386B1 (ko) * | 2011-12-07 | 2015-02-23 | 삼성전자주식회사 | 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산을 생산하는 재조합 미생물 및 이를 이용한 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산의 생산방법 |
| JP6173314B2 (ja) | 2012-06-27 | 2017-08-02 | 株式会社日本触媒 | (メタ)アクリル酸の製造方法、及び、親水性樹脂の製造方法 |
| CN109182238A (zh) | 2012-08-10 | 2019-01-11 | 嘉吉有限公司 | 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法 |
| WO2014085330A1 (en) | 2012-11-30 | 2014-06-05 | Novozymes, Inc. | 3-hydroxypropionic acid production by recombinant yeasts |
| CN104903287A (zh) * | 2013-01-08 | 2015-09-09 | 国际壳牌研究有限公司 | 丙烯酸的生产 |
| WO2014146026A1 (en) | 2013-03-15 | 2014-09-18 | Opx Biotechnologies, Inc. | Bioproduction of chemicals |
| WO2014145096A1 (en) | 2013-03-15 | 2014-09-18 | Cindy Hoppe | Flash evaporation for production purification and recovery |
| WO2014198841A1 (en) | 2013-06-14 | 2014-12-18 | Technical University Of Denmark | 3hp tolerance |
| US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| JP6603658B2 (ja) | 2013-07-19 | 2019-11-06 | カーギル インコーポレイテッド | 脂肪酸及び脂肪酸誘導体の製造のための微生物及び方法 |
| WO2015058118A1 (en) | 2013-10-17 | 2015-04-23 | Cargill, Incorporated | Method for producing alkyl hydroxyalkanoates |
| EP2993228B1 (de) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Herstellung von fettsäureestern |
| WO2016061356A1 (en) | 2014-10-17 | 2016-04-21 | Cargill, Incorporated | Methods for producing an ester of an alpha, beta-unsaturated carboxylic acid |
| CN107406821B (zh) | 2015-02-27 | 2021-10-15 | 诺维信公司 | 用于生产3-羟基丙酸的突变宿主细胞 |
| WO2018059745A1 (en) | 2016-09-27 | 2018-04-05 | Shell Internationale Research Maatschappij B.V. | Process for production of allyl alcohol |
| WO2018144701A2 (en) | 2017-02-02 | 2018-08-09 | Cargill Incorporated | Genetically modified cells that produce c6-c10 fatty acid derivatives |
| WO2019143621A1 (en) * | 2018-01-16 | 2019-07-25 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for inhibiting aldh2 expression |
| JP2023531938A (ja) * | 2020-07-31 | 2023-07-26 | エルジー・ケム・リミテッド | 3-ヒドロキシプロピオン酸の2段階製造方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9712761B1 (pt) * | 1996-11-13 | 2010-02-23 | mÉtodo para a produÇço de 1,3- propanodiol e microorganismo hospedeiro transformado. | |
| WO2000008198A1 (en) * | 1998-08-04 | 2000-02-17 | Metabolix, Inc. | Polyhydroxyalkanoate production from polyols |
-
2000
- 2000-08-30 AU AU70936/00A patent/AU7093600A/en not_active Abandoned
- 2000-08-30 WO PCT/US2000/023878 patent/WO2001016346A1/en not_active Ceased
- 2000-08-30 DE DE60030403T patent/DE60030403D1/de not_active Expired - Fee Related
- 2000-08-30 AT AT00959652T patent/ATE338139T1/de not_active IP Right Cessation
- 2000-08-30 BR BR0008355-0A patent/BR0008355A/pt not_active IP Right Cessation
- 2000-08-30 EP EP00959652A patent/EP1124979B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001016346A1 (en) | 2001-03-08 |
| DE60030403D1 (de) | 2006-10-12 |
| EP1124979A4 (de) | 2002-08-28 |
| EP1124979A1 (de) | 2001-08-22 |
| AU7093600A (en) | 2001-03-26 |
| EP1124979B1 (de) | 2006-08-30 |
| BR0008355A (pt) | 2002-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |