ATE338139T1 - Herstellung von 3-hydroxypropionsäure in rekombinanten organismen - Google Patents

Herstellung von 3-hydroxypropionsäure in rekombinanten organismen

Info

Publication number
ATE338139T1
ATE338139T1 AT00959652T AT00959652T ATE338139T1 AT E338139 T1 ATE338139 T1 AT E338139T1 AT 00959652 T AT00959652 T AT 00959652T AT 00959652 T AT00959652 T AT 00959652T AT E338139 T1 ATE338139 T1 AT E338139T1
Authority
AT
Austria
Prior art keywords
production
hydroxypropionic acid
recombinant organisms
bacterial host
glycerol
Prior art date
Application number
AT00959652T
Other languages
English (en)
Inventor
Patrick F Suthers
Douglas C Cameron
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Application granted granted Critical
Publication of ATE338139T1 publication Critical patent/ATE338139T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/01Hydro-lyases (4.2.1)
    • C12Y402/0103Glycerol dehydratase (4.2.1.30)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT00959652T 1999-08-30 2000-08-30 Herstellung von 3-hydroxypropionsäure in rekombinanten organismen ATE338139T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15144099P 1999-08-30 1999-08-30

Publications (1)

Publication Number Publication Date
ATE338139T1 true ATE338139T1 (de) 2006-09-15

Family

ID=22538777

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00959652T ATE338139T1 (de) 1999-08-30 2000-08-30 Herstellung von 3-hydroxypropionsäure in rekombinanten organismen

Country Status (6)

Country Link
EP (1) EP1124979B1 (de)
AT (1) ATE338139T1 (de)
AU (1) AU7093600A (de)
BR (1) BR0008355A (de)
DE (1) DE60030403D1 (de)
WO (1) WO2001016346A1 (de)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7186541B2 (en) 2000-11-20 2007-03-06 Cargill, Incorporated 3-hydroxypropionic acid and other organic compounds
EP1575881B1 (de) 2002-01-18 2009-05-27 Novozymes A/S Alanin-2,3-aminomutase
AU2003207708A1 (en) * 2002-02-20 2003-09-09 Sirna Therapeutics, Inc. Rna interference mediated inhibition of map kinase genes
ATE413456T1 (de) * 2002-03-13 2008-11-15 Evonik Degussa Gmbh Verfahren zur herstellung von l-aminosäuren unter verwendung von stämmen der familie enterobacteriaceae
DE10210960A1 (de) * 2002-03-13 2003-09-25 Degussa Verfahren zur fermentativen Hestellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
CN1781897A (zh) * 2002-03-25 2006-06-07 嘉吉有限公司 制造β-羟基羧酸烷氧基衍生物的方法
WO2005118719A2 (en) 2003-12-04 2005-12-15 Cargill, Incorporated Production of 3-hydroxypropionic acid using beta-alanine/pyruvate aminotransferase
MX2007001195A (es) 2004-07-30 2007-10-03 Cargill Inc Alanina 2,3-aminomutasas.
JP2008517607A (ja) 2004-10-25 2008-05-29 コデクシス, インコーポレイテッド 改良されたアラニン2,3−アミノムターゼおよび関連ポリヌクレオチド
TWI529181B (zh) * 2005-02-28 2016-04-11 贏創德固賽有限責任公司 以可更新原料為基之吸水聚合物結構及其生產的方法
JP2007082476A (ja) * 2005-09-22 2007-04-05 Nippon Shokubai Co Ltd グリセリンから3−ヒドロキシプロピオン酸を製造する方法
DE102005048818A1 (de) 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
WO2007047773A2 (en) 2005-10-14 2007-04-26 Codexis, Inc. Alanine 2,3-aminomutases and related polynucleotides
DE102006039203B4 (de) 2006-08-22 2014-06-18 Evonik Degussa Gmbh Verfahren zur Herstellung von durch Kristallisation gereinigter Acrylsäure aus Hydroxypropionsäure sowie Vorrichtung dazu
DE102007015583A1 (de) 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
CN107090424A (zh) 2008-01-22 2017-08-25 基因组股份公司 利用合成气或其它气态碳源和甲醇的方法和有机体
EP3450550A1 (de) 2008-03-05 2019-03-06 Genomatica, Inc. Primäre, alkohole produzierende organismen
WO2009135074A2 (en) 2008-05-01 2009-11-05 Genomatica, Inc. Microorganisms for the production of methacrylic acid
EP2308913B1 (de) 2008-07-30 2016-04-20 Mitsui Chemicals, Inc. Polyesterpolyol, zusammensetzung für polyurethan, zusammensetzung für polyurethanschaumstoff, polyurethanharz und polyurethanschaumstoff
EP3865569B1 (de) 2009-04-30 2023-10-04 Genomatica, Inc. Organismen zur herstellung von 1,3-butandiol
BRPI1013505A2 (pt) 2009-04-30 2018-02-14 Genomatica Inc organismos para a produção de isopropanol, n-butanol, e isobutanol
SG175379A1 (en) 2009-05-15 2011-12-29 Nippon Catalytic Chem Ind Process for producing (meth)acrylic acid and crystallization system
WO2010131589A1 (ja) 2009-05-15 2010-11-18 株式会社日本触媒 (メタ)アクリル酸の製造方法
US8586787B2 (en) 2009-05-15 2013-11-19 Nippon Shokubai Co., Ltd. Process for producing (meth)acrylic acid
DK2462221T3 (en) 2009-08-05 2017-05-22 Genomatica Inc SEMISYNTHETIC TEREPHTHALIC ACID BY MICRO-ORGANISMS PRODUCING MUCONIC ACID
CA2775390C (en) 2009-09-27 2021-06-29 Opx Biotechnologies, Inc. Method for producing 3-hydroxypropionic acid and other products
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
US20110097767A1 (en) 2009-10-23 2011-04-28 Priti Pharkya Microorganisms for the production of aniline
CN102933715B (zh) * 2009-10-29 2015-04-29 韩国生命工学研究院 从甘油生产3-羟基丙酸的方法
CN102834508A (zh) 2010-01-29 2012-12-19 基因组股份公司 用于生物合成对甲苯甲酸和对苯二甲酸的微生物和方法
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
EP2588598B1 (de) 2010-07-02 2016-03-09 Metabolic Explorer Verfahren zur herstellung von hydroxysäuren
WO2012018624A2 (en) 2010-07-26 2012-02-09 Genomatica, Inc. Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
US10138504B2 (en) 2010-08-06 2018-11-27 Lallemand Hungary Liquidity Management Llc Production of malonyl-CoA derived products via anaerobic pathways
AU2011336923B2 (en) 2010-11-22 2017-02-16 Cargill, Incorporated Compositions and methods for 3-hydroxypropionic acid production
EP2660235A4 (de) 2010-12-28 2016-01-20 Nippon Catalytic Chem Ind Verfahren zur herstellung von acrylsäure und/oder einem ester davon und polymer aus der acrylsäure und/oder dem ester davon
BR112014007647A2 (pt) 2011-09-30 2017-04-18 Novozymes As “variante de 3-hpdh, polipeptídeo tendo atividade de 3-hpdh, polinucleotídeo isolado, célula hospedeira microbiana transgênica, e, método para produzir 3-hp
WO2013085321A1 (ko) * 2011-12-07 2013-06-13 삼성전자주식회사 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산을 생산하는 재조합 미생물 및 이를 이용한 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산의 생산방법
KR101494386B1 (ko) * 2011-12-07 2015-02-23 삼성전자주식회사 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산을 생산하는 재조합 미생물 및 이를 이용한 3-하이드록시프로피온알데히드 및/또는 3-하이드록시프로피온산의 생산방법
JP6173314B2 (ja) 2012-06-27 2017-08-02 株式会社日本触媒 (メタ)アクリル酸の製造方法、及び、親水性樹脂の製造方法
CN109182238A (zh) 2012-08-10 2019-01-11 嘉吉有限公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
WO2014085330A1 (en) 2012-11-30 2014-06-05 Novozymes, Inc. 3-hydroxypropionic acid production by recombinant yeasts
CN104903287A (zh) * 2013-01-08 2015-09-09 国际壳牌研究有限公司 丙烯酸的生产
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
WO2014145096A1 (en) 2013-03-15 2014-09-18 Cindy Hoppe Flash evaporation for production purification and recovery
WO2014198841A1 (en) 2013-06-14 2014-12-18 Technical University Of Denmark 3hp tolerance
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
JP6603658B2 (ja) 2013-07-19 2019-11-06 カーギル インコーポレイテッド 脂肪酸及び脂肪酸誘導体の製造のための微生物及び方法
WO2015058118A1 (en) 2013-10-17 2015-04-23 Cargill, Incorporated Method for producing alkyl hydroxyalkanoates
EP2993228B1 (de) 2014-09-02 2019-10-09 Cargill, Incorporated Herstellung von fettsäureestern
WO2016061356A1 (en) 2014-10-17 2016-04-21 Cargill, Incorporated Methods for producing an ester of an alpha, beta-unsaturated carboxylic acid
CN107406821B (zh) 2015-02-27 2021-10-15 诺维信公司 用于生产3-羟基丙酸的突变宿主细胞
WO2018059745A1 (en) 2016-09-27 2018-04-05 Shell Internationale Research Maatschappij B.V. Process for production of allyl alcohol
WO2018144701A2 (en) 2017-02-02 2018-08-09 Cargill Incorporated Genetically modified cells that produce c6-c10 fatty acid derivatives
WO2019143621A1 (en) * 2018-01-16 2019-07-25 Dicerna Pharmaceuticals, Inc. Compositions and methods for inhibiting aldh2 expression
JP2023531938A (ja) * 2020-07-31 2023-07-26 エルジー・ケム・リミテッド 3-ヒドロキシプロピオン酸の2段階製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9712761B1 (pt) * 1996-11-13 2010-02-23 mÉtodo para a produÇço de 1,3- propanodiol e microorganismo hospedeiro transformado.
WO2000008198A1 (en) * 1998-08-04 2000-02-17 Metabolix, Inc. Polyhydroxyalkanoate production from polyols

Also Published As

Publication number Publication date
WO2001016346A1 (en) 2001-03-08
DE60030403D1 (de) 2006-10-12
EP1124979A4 (de) 2002-08-28
EP1124979A1 (de) 2001-08-22
AU7093600A (en) 2001-03-26
EP1124979B1 (de) 2006-08-30
BR0008355A (pt) 2002-07-16

Similar Documents

Publication Publication Date Title
DE60030403D1 (de) Herstellung von 3-hydroxypropionsäure in rekombinanten organismen
Fukushima et al. Production of D‐lactic acid by bacterial fermentation of rice starch
DE69636903D1 (de) Herstellung von 1,3-propandiol aus glycerol mit rekombinanten diol-dehydratase exprimierenden bakterien
Song et al. A pre-genetic study of the isoforms of malic enzyme associated with lipid accumulation in Mucor circinelloides
MX9708687A (es) Bioconversion de una fuente de carbono fermentable a 1,3-propanodiol por un solo microorganismo.
ATE330022T1 (de) Verfahren zur herstellung einer zielsubstanz durch fermentation
DE69938105D1 (de) Herstellung von polyhydroxyalkanoaten aus polyolen
HK1052534A1 (zh) 3-羟基羧酸的制备方法以及在支化聚合物中的用途
Laffend et al. Bioconversion of a fermentable carbon source to 1, 3-propanediol by a single microorganism
AU6431600A (en) Process for the fermentative preparation of l-amino acids with amplification of the gnd gene
AU5982200A (en) Process for the fermentative preparation of l-amino acids with amplification of the tkt gene
KR960041357A (ko) 미생물, 이의 용도 및 이를 이용한 L-α-아미노산의 제조방법
Asano et al. Isolation of poly (3-hydroxybutyrate)(PHB)-degrading microorganisms and characterization of PHB-depolymerase from Arthrobacter sp. strain W6
DE50115182D1 (de) Butinol i esterase
Laffend et al. Bioconversion of a fermentable carbon source to 1, 3-propanediol by a single microorganism
ES8504932A1 (es) Un metodo para convertir carbohidratos en acido acetico.
Genov et al. HYDROLYSIS OF AMINO‐ACID ESTERS BY ALKALINE MESENTERICOPEPTIDASE
EP0258666A3 (de) Mikrobisch-enzymatische Transformierungen von Chrysanthemol, Lavandulol und analogen Alkoholen in Säuren
EP1585821A4 (de) BIOKONVERSION VON XYLAN UND LEVULINSäURE ZU BIOLOGISCH ABBAUBAREN THERMOPLASTEN
LV12359A (lv) Fermentativs panemiens 7beta-(4-karboksibutan-amid)cefalosporanskabes iegusanai izmantojot modificetu trigonopsis variabilis fermentu d-aminoskabju oksidazi kas produceta escherichia coli
Nakagawa et al. Properties of the extracellular lytic proteinase of Pseudomonas sp.
WO2001090370A3 (de) Verfahren zur mikrobiellen herstellung von difructoseanhydrid-iii, dafür einsetzbarer mikroorganismus sowie enzym mit inulase-ii-aktivität und dafür kodierende dna-sequenzen
WO2009028294A1 (ja) 変異型リパーゼとその利用
SU1645291A1 (ru) Питательна среда дл глубинного культивировани BacILLUS SUвтILIS ВКПМ В-2595 - продуцента L-амилазы
中川孝之 et al. Properties of the extracellular lytic proteinase of Pseudomonas sp..

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties