ATE340174T1 - Verfahren zur umwandlung von dihidroisoxazol derivate in gamma-hydroxaminsäurederivate, z.b monatins - Google Patents
Verfahren zur umwandlung von dihidroisoxazol derivate in gamma-hydroxaminsäurederivate, z.b monatinsInfo
- Publication number
- ATE340174T1 ATE340174T1 AT03005268T AT03005268T ATE340174T1 AT E340174 T1 ATE340174 T1 AT E340174T1 AT 03005268 T AT03005268 T AT 03005268T AT 03005268 T AT03005268 T AT 03005268T AT E340174 T1 ATE340174 T1 AT E340174T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- monatins
- gamma
- dihidroisoxazole
- converting
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 2
- YBKZKMWNFKMYEX-UHFFFAOYSA-N 5-(1h-indol-2-ylmethyl)-4h-1,2-oxazole-3,5-dicarboxylic acid Chemical compound C1C(C(=O)O)=NOC1(C(O)=O)CC1=CC2=CC=CC=C2N1 YBKZKMWNFKMYEX-UHFFFAOYSA-N 0.000 abstract 1
- 125000005048 dihydroisoxazolyl group Chemical class O1N(CC=C1)* 0.000 abstract 1
- 235000003599 food sweetener Nutrition 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000003765 sweetening agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002098515A JP2003292484A (ja) | 2002-04-01 | 2002-04-01 | γ−ヒドロキシアミノ酸誘導体及びモナティン類の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE340174T1 true ATE340174T1 (de) | 2006-10-15 |
Family
ID=28035889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03005268T ATE340174T1 (de) | 2002-04-01 | 2003-03-10 | Verfahren zur umwandlung von dihidroisoxazol derivate in gamma-hydroxaminsäurederivate, z.b monatins |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7329427B2 (de) |
| EP (1) | EP1350791B1 (de) |
| JP (1) | JP2003292484A (de) |
| AT (1) | ATE340174T1 (de) |
| CA (1) | CA2423691C (de) |
| DE (1) | DE60308435T2 (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4991091B2 (ja) * | 2001-11-30 | 2012-08-01 | 味の素株式会社 | モナティンの非天然型立体異性体塩の結晶及びその使用 |
| US7297800B2 (en) * | 2001-12-27 | 2007-11-20 | Ajinomoto Co., Inc. | Process of producing glutamate derivatives |
| JP4196832B2 (ja) * | 2001-12-27 | 2008-12-17 | 味の素株式会社 | グルタミン酸化合物及びそれらの製造中間体の製造方法並びにそのための新規中間体 |
| JP2003292484A (ja) | 2002-04-01 | 2003-10-15 | Ajinomoto Co Inc | γ−ヒドロキシアミノ酸誘導体及びモナティン類の製造方法 |
| US8372989B2 (en) | 2002-04-23 | 2013-02-12 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
| US7572607B2 (en) * | 2002-04-23 | 2009-08-11 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
| DK1533376T3 (da) | 2002-08-26 | 2010-07-19 | Ajinomoto Kk | Nye aldolaser og fremgangsmåde til fremstilling af substitueret alfa-ketosyre |
| CN1723281B (zh) | 2002-12-09 | 2012-08-15 | 味之素株式会社 | 突变的d-氨基转移酶和使用它们生产旋光性谷氨酸衍生物的方法 |
| AU2003301508A1 (en) * | 2003-01-09 | 2004-08-23 | Ajinomoto Co., Inc. | Processes for producing glutamic acid derivative and pyroglutamic acid derivative and novel intermediate for production |
| US20050112260A1 (en) * | 2003-08-01 | 2005-05-26 | Cargill, Inc. | Monatin tabletop sweetener compositions and methods of making same |
| ATE360370T1 (de) * | 2003-08-14 | 2007-05-15 | Cargill Inc | Monatinhaltige kaugummizusammensetzungen und verfahren zu ihrer herstellung |
| US20050106305A1 (en) * | 2003-08-25 | 2005-05-19 | Cargill, Inc. | Beverage compositions comprising monatin and methods of making same |
| CN1890377B (zh) | 2003-10-21 | 2013-06-05 | 嘉吉有限公司 | 生产莫纳甜和莫纳甜前体 |
| JP5113978B2 (ja) * | 2003-11-21 | 2013-01-09 | 味の素株式会社 | グルタミン酸誘導体の有機アミン塩及びその利用 |
| WO2005082850A1 (ja) * | 2004-02-27 | 2005-09-09 | Ajinomoto Co., Inc. | モナティンの製造方法 |
| US7935377B2 (en) * | 2004-06-04 | 2011-05-03 | Ajinomoto Co., Inc. | Crystals of free (2R, 4R)-monatin and use thereof |
| CA2506247C (en) * | 2004-06-07 | 2012-02-21 | Ajinomoto Co., Inc. | Novel aldolase, and method for producing optically active ihog and monatin |
| KR20070062542A (ko) * | 2004-10-05 | 2007-06-15 | 아지노모토 가부시키가이샤 | 하이드록시이미노산으로부터 아미노산 유도체의 제조방법 |
| RU2392834C2 (ru) * | 2004-10-15 | 2010-06-27 | Адзиномото Ко., Инк. | Композиция подсластителя |
| WO2006113897A2 (en) | 2005-04-20 | 2006-10-26 | Cargill, Incorporated | Products and methods for in vivo secretion of monatin |
| US8158389B2 (en) | 2005-04-20 | 2012-04-17 | Cargill, Incorporated | Products and methods for in vivo secretion of monatin |
| US8076108B2 (en) | 2005-04-26 | 2011-12-13 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
| JP5336182B2 (ja) * | 2005-04-26 | 2013-11-06 | カーギル，インコーポレイティド | モナティンの立体異性体及びそれらの前駆体の製造のためのポリペプチド及び生合成経路 |
| US7582455B2 (en) | 2005-04-26 | 2009-09-01 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
| US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
| EP2112227B1 (de) | 2006-03-07 | 2013-05-15 | Cargill, Incorporated | Aldolasen, Nukleinsäuren zu ihrer Kodierung sowie Verfahren zu ihrer Herstellung und Verwendung |
| CN101490249A (zh) | 2006-05-24 | 2009-07-22 | 嘉吉公司 | 提高平衡反应的产量的方法和系统 |
| US20090198072A1 (en) * | 2006-05-24 | 2009-08-06 | Cargill, Incorporated | Methods and systems for increasing production of equilibrium reactions |
| US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
| US8076107B2 (en) * | 2007-10-01 | 2011-12-13 | Cargill, Incorporated | Production of monatin stereoisomers |
| US8003361B2 (en) | 2007-10-01 | 2011-08-23 | Cargill Incorporated | Production of monatin enantiomers |
| US8367847B2 (en) | 2007-10-01 | 2013-02-05 | Cargill, Incorporated | Production of monatin enantiomers |
| EP2107053A1 (de) * | 2008-03-11 | 2009-10-07 | Ajinomoto Co., Inc. | Hydratkristalle von (2R,4R)-Monatin Mononatrium-Salz |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69101791T2 (de) * | 1990-01-19 | 1994-08-11 | Technology Finance Corp | Verfahren zur Herstellung von 3-(1-Amino-1,3-dicarboxy-3-hydroxy-but-4-yl)-indol. |
| US5994559A (en) | 1998-08-06 | 1999-11-30 | The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations | Synthesis of monatin-A high intensity natural sweetener |
| JP2002060382A (ja) * | 2000-08-22 | 2002-02-26 | Ajinomoto Co Inc | モナティンの立体異性体及びその使用、並びにモナティン類の製造方法及びそのための中間体 |
| JP2003292484A (ja) | 2002-04-01 | 2003-10-15 | Ajinomoto Co Inc | γ−ヒドロキシアミノ酸誘導体及びモナティン類の製造方法 |
-
2002
- 2002-04-01 JP JP2002098515A patent/JP2003292484A/ja active Pending
-
2003
- 2003-03-10 EP EP03005268A patent/EP1350791B1/de not_active Expired - Lifetime
- 2003-03-10 AT AT03005268T patent/ATE340174T1/de not_active IP Right Cessation
- 2003-03-10 DE DE60308435T patent/DE60308435T2/de not_active Expired - Lifetime
- 2003-03-27 CA CA2423691A patent/CA2423691C/en not_active Expired - Fee Related
- 2003-03-27 US US10/397,407 patent/US7329427B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20030228403A1 (en) | 2003-12-11 |
| DE60308435D1 (de) | 2006-11-02 |
| DE60308435T2 (de) | 2007-05-03 |
| EP1350791A1 (de) | 2003-10-08 |
| JP2003292484A (ja) | 2003-10-15 |
| CA2423691A1 (en) | 2003-10-01 |
| CA2423691C (en) | 2010-09-14 |
| EP1350791B1 (de) | 2006-09-20 |
| US7329427B2 (en) | 2008-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |