ATE486857T1 - Verfahren zur herstellung von telmisartan - Google Patents
Verfahren zur herstellung von telmisartanInfo
- Publication number
- ATE486857T1 ATE486857T1 AT06007978T AT06007978T ATE486857T1 AT E486857 T1 ATE486857 T1 AT E486857T1 AT 06007978 T AT06007978 T AT 06007978T AT 06007978 T AT06007978 T AT 06007978T AT E486857 T1 ATE486857 T1 AT E486857T1
- Authority
- AT
- Austria
- Prior art keywords
- telmisartan
- producing telmisartan
- producing
- synthesis
- preparation
- Prior art date
Links
- RMMXLENWKUUMAY-UHFFFAOYSA-N telmisartan Chemical compound CCCC1=NC2=C(C)C=C(C=3N(C4=CC=CC=C4N=3)C)C=C2N1CC(C=C1)=CC=C1C1=CC=CC=C1C(O)=O RMMXLENWKUUMAY-UHFFFAOYSA-N 0.000 title abstract 4
- 239000005537 C09CA07 - Telmisartan Substances 0.000 title abstract 2
- 229960005187 telmisartan Drugs 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Manufacture, Treatment Of Glass Fibers (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Discharge By Other Means (AREA)
- Chemical Treatment Of Metals (AREA)
- Photoreceptors In Electrophotography (AREA)
- Earth Drilling (AREA)
- Saccharide Compounds (AREA)
- Eye Examination Apparatus (AREA)
- Paper (AREA)
- Electric Cable Installation (AREA)
- Valve-Gear Or Valve Arrangements (AREA)
- Sheet Holders (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000801A ITMI20050801A1 (it) | 2005-05-03 | 2005-05-03 | Procedimento per la preparazione di telmisartan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE486857T1 true ATE486857T1 (de) | 2010-11-15 |
Family
ID=36693139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06007978T ATE486857T1 (de) | 2005-05-03 | 2006-04-18 | Verfahren zur herstellung von telmisartan |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7692027B2 (de) |
| EP (1) | EP1719766B1 (de) |
| JP (1) | JP2006312632A (de) |
| AT (1) | ATE486857T1 (de) |
| CA (1) | CA2545595A1 (de) |
| DE (1) | DE602006017918D1 (de) |
| ES (1) | ES2353640T3 (de) |
| IL (1) | IL175390A0 (de) |
| IT (1) | ITMI20050801A1 (de) |
| PT (1) | PT1719766E (de) |
| SI (1) | SI1719766T1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2007004426A (es) * | 2004-10-15 | 2007-06-14 | Teva Pharma | Procesos para preparar telmisartan. |
| ITMI20061365A1 (it) * | 2006-07-13 | 2008-01-14 | Dipharma Spa | Procedimento per la preparazione di acidi boronici e loro derivati |
| CA2718891C (en) | 2008-03-20 | 2016-10-18 | Lek Pharmaceuticals D.D. | 2'-halobiphenyl-4-yl intermediates in the synthesis of angiotensin ii antagonists |
| EP2103609A1 (de) * | 2008-03-20 | 2009-09-23 | Lek Pharmaceuticals D.D. | Katalysierte Carbonylierung bei der Synthese von Angiotensin-II-Antagonisten |
| WO2009123483A1 (en) | 2008-03-31 | 2009-10-08 | Zaklady Farmaceutyczne Polpharma Sa | Process for preparation of telmisartan |
| EP2123648A1 (de) | 2008-05-20 | 2009-11-25 | Chemo Ibérica, S.A. | Verfahren zur Herstellung von Telmisartan |
| EP2149566A1 (de) | 2008-07-15 | 2010-02-03 | Chemo Ibérica, S.A. | Verfahren zur Herstellung von Telmisartan |
| WO2010018441A2 (en) * | 2008-08-11 | 2010-02-18 | Cadila Pharmaceuticals Ltd. | An improved process for the preparation of substantially pure telmisartan |
| ES2415357T3 (es) | 2009-06-19 | 2013-07-25 | Krka Tovarna Zdravil, D.D., Novo Mesto | Procedimiento para la preparación de telmisartán |
| EP2305650A1 (de) | 2009-09-21 | 2011-04-06 | Chemo Ibérica, S.A. | Neuartiges Verfahren zur Herstellung von Telmisartan |
| JP5711888B2 (ja) * | 2010-01-26 | 2015-05-07 | 株式会社Ｄｎｐファインケミカル宇都宮 | テルミサルタンアルキルエステルの製造法 |
| WO2012055941A1 (en) | 2010-10-27 | 2012-05-03 | Krka,Tovarna Zdravil, D. D., Novo Mesto | Multilayer pharmaceutical composition comprising telmisartan and amlodipine |
| CN105130905B (zh) * | 2015-09-17 | 2017-09-08 | 浙江金立源药业有限公司 | 一种替米沙坦的合成方法 |
| KR101872726B1 (ko) | 2016-07-28 | 2018-06-29 | 주식회사 씨트리 | 텔미사르탄 메탄술폰산염 및 이를 포함하는 약제학적 조성물 |
| CN108218789A (zh) * | 2018-03-12 | 2018-06-29 | 钦州学院 | 碳13氘代甲基替米沙坦及其制备方法和用途 |
| CN108329269A (zh) * | 2018-03-12 | 2018-07-27 | 钦州学院 | 氘代甲基替米沙坦及其制备方法和用途 |
| CN109020896A (zh) * | 2018-09-13 | 2018-12-18 | 湖北舒邦药业有限公司 | 替米沙坦钠盐以及其制备方法 |
| ES2960987T3 (es) | 2019-04-12 | 2024-03-07 | Riboscience Llc | Derivados de heteroarilo bicíclicos como inhibidores de la ectonucleótido pirofosfatasa fosfodiesterasa 1 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI9210098B (sl) * | 1991-02-06 | 2000-06-30 | Dr. Karl Thomae | Benzimidazoli, zdravila, ki te spojine vsebujejo, in postopek za njihovo pripravo |
| DE4142366A1 (de) * | 1991-07-15 | 1993-06-24 | Thomae Gmbh Dr K | Phenylalkylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| US6737432B2 (en) * | 2001-10-31 | 2004-05-18 | Boehringer Ingelheim Pharma Kg | Crystalline form of telmisartan sodium |
| US20050020654A1 (en) * | 2003-03-15 | 2005-01-27 | Pershadsingh Harrihar A. | Novel PPAR agonists, pharmaceutical compositions and uses thereof |
| DE10314702A1 (de) * | 2003-03-31 | 2004-10-21 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung von Telmisartan |
-
2005
- 2005-05-03 IT IT000801A patent/ITMI20050801A1/it unknown
-
2006
- 2006-04-18 PT PT06007978T patent/PT1719766E/pt unknown
- 2006-04-18 ES ES06007978T patent/ES2353640T3/es not_active Expired - Lifetime
- 2006-04-18 AT AT06007978T patent/ATE486857T1/de not_active IP Right Cessation
- 2006-04-18 SI SI200630869T patent/SI1719766T1/sl unknown
- 2006-04-18 DE DE602006017918T patent/DE602006017918D1/de not_active Expired - Lifetime
- 2006-04-18 EP EP06007978A patent/EP1719766B1/de not_active Expired - Lifetime
- 2006-05-02 IL IL175390A patent/IL175390A0/en unknown
- 2006-05-02 US US11/415,429 patent/US7692027B2/en not_active Expired - Fee Related
- 2006-05-02 JP JP2006128087A patent/JP2006312632A/ja active Pending
- 2006-05-02 CA CA002545595A patent/CA2545595A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE602006017918D1 (de) | 2010-12-16 |
| US7692027B2 (en) | 2010-04-06 |
| EP1719766A2 (de) | 2006-11-08 |
| PT1719766E (pt) | 2010-12-29 |
| IL175390A0 (en) | 2006-09-05 |
| US20060264644A1 (en) | 2006-11-23 |
| JP2006312632A (ja) | 2006-11-16 |
| SI1719766T1 (sl) | 2011-02-28 |
| EP1719766A3 (de) | 2006-12-20 |
| EP1719766B1 (de) | 2010-11-03 |
| CA2545595A1 (en) | 2006-11-03 |
| ES2353640T3 (es) | 2011-03-03 |
| ITMI20050801A1 (it) | 2006-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |