ATE340584T1 - Zusammensetzung und verfahren zur behandlung chronischer allograft-abstossung - Google Patents

Zusammensetzung und verfahren zur behandlung chronischer allograft-abstossung

Info

Publication number: ATE340584T1
Authority: AT; Austria
Prior art keywords: composition; allograft rejection; chronic allograft; treating chronic; therapeutically effective
Prior art date: 2001-12-05

Application number

AT02804721T

Other languages

English (en)

Inventor

Daniel R Salomon

Donald V Cramer

Original Assignee

Scripps Research Inst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-05

Filing date

2002-12-05

Publication date

2006-10-15

2002-12-05 Application filed by Scripps Research Inst filed Critical Scripps Research Inst

2006-10-15 Application granted granted Critical

2006-10-15 Publication of ATE340584T1 publication Critical patent/ATE340584T1/de

Links

230000001684 chronic effect Effects 0.000 title abstract 2
PTOAARAWEBMLNO-KVQBGUIXSA-N Cladribine Chemical compound C1=NC=2C(N)=NC(Cl)=NC=2N1[C@H]1C[C@H](O)[C@@H](CO)O1 PTOAARAWEBMLNO-KVQBGUIXSA-N 0.000 abstract 1
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
229930105110 Cyclosporin A Natural products 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
229930182912 cyclosporin Natural products 0.000 abstract 1
239000003018 immunosuppressive agent Substances 0.000 abstract 1
229940124589 immunosuppressive drug Drugs 0.000 abstract 1
210000000056 organ Anatomy 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Heart & Thoracic Surgery (AREA)
Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Transplantation (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT02804721T 2001-12-05 2002-12-05 Zusammensetzung und verfahren zur behandlung chronischer allograft-abstossung ATE340584T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US10/006,562 US7368423B1 (en)	2001-12-05	2001-12-05	Composition and method for treating chronic allograft rejection

Publications (1)

Publication Number	Publication Date
ATE340584T1 true ATE340584T1 (de)	2006-10-15

Family

ID=21721475

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02804721T ATE340584T1 (de)	2001-12-05	2002-12-05	Zusammensetzung und verfahren zur behandlung chronischer allograft-abstossung

Country Status (13)

Country	Link
US (1)	US7368423B1 (de)
EP (1)	EP1461062B1 (de)
JP (1)	JP2005530680A (de)
AT (1)	ATE340584T1 (de)
AU (1)	AU2002357062B2 (de)
CA (1)	CA2465120A1 (de)
CY (1)	CY1106242T1 (de)
DE (1)	DE60215051T2 (de)
DK (1)	DK1461062T3 (de)
ES (1)	ES2269825T3 (de)
MX (1)	MXPA04005097A (de)
PT (1)	PT1461062E (de)
WO (1)	WO2003049682A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2462262C2 (ru)	2007-01-04	2012-09-27	Дебиофарм С А	Неиммуносупрессорный циклоспорин для лечения врожденной миопатии ульриха

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5310732A (en) *	1986-02-03	1994-05-10	The Scripps Research Institute	2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis
WO1995032718A1 (en) *	1994-05-26	1995-12-07	The Scripps Research Institute	2-halo-2'-deoxyadenosine treatement for inflammatory bowel disease
AR006514A1 (es) *	1995-07-04	1999-09-08	Sandoz Ag	Un macrolido, sus usos, un proceso para producirlo, un aislado biologicamente puro capaz de producirlo, y una composicion farmaceutica quelo comprende
DE19547648A1 (de) *	1995-12-20	1997-06-26	Hoechst Ag	Zubereitung, enthaltend High Density Lipoproteine und Crotonsäureamidderivate
JPH11228442A (ja) *	1998-02-09	1999-08-24	Cypros Pharmaceut Corp	臓器移植後のシクロスポリン投与量を低減するためのフルクトース二リン酸の使用

2001
- 2001-12-05 US US10/006,562 patent/US7368423B1/en not_active Expired - Fee Related
2002
- 2002-12-05 AU AU2002357062A patent/AU2002357062B2/en not_active Ceased
- 2002-12-05 ES ES02804721T patent/ES2269825T3/es not_active Expired - Lifetime
- 2002-12-05 DE DE60215051T patent/DE60215051T2/de not_active Expired - Lifetime
- 2002-12-05 CA CA002465120A patent/CA2465120A1/en not_active Abandoned
- 2002-12-05 EP EP02804721A patent/EP1461062B1/de not_active Expired - Lifetime
- 2002-12-05 WO PCT/US2002/038628 patent/WO2003049682A2/en not_active Ceased
- 2002-12-05 PT PT02804721T patent/PT1461062E/pt unknown
- 2002-12-05 AT AT02804721T patent/ATE340584T1/de active
- 2002-12-05 JP JP2003550733A patent/JP2005530680A/ja active Pending
- 2002-12-05 DK DK02804721T patent/DK1461062T3/da active
2004
- 2004-05-27 MX MXPA04005097A patent/MXPA04005097A/es active IP Right Grant
2006
- 2006-11-14 CY CY20061101654T patent/CY1106242T1/el unknown

Also Published As

Publication number	Publication date
CY1106242T1 (el)	2011-06-08
WO2003049682A3 (en)	2004-01-15
MXPA04005097A (es)	2004-08-19
EP1461062A4 (de)	2005-03-16
AU2002357062B2 (en)	2007-08-02
ES2269825T3 (es)	2007-04-01
EP1461062B1 (de)	2006-09-27
DE60215051D1 (de)	2006-11-09
PT1461062E (pt)	2006-12-29
DE60215051T2 (de)	2007-05-16
JP2005530680A (ja)	2005-10-13
DK1461062T3 (da)	2007-01-08
AU2002357062A1 (en)	2003-06-23
WO2003049682A2 (en)	2003-06-19
CA2465120A1 (en)	2003-06-19
EP1461062A2 (de)	2004-09-29
HK1064610A1 (en)	2005-02-04
US7368423B1 (en)	2008-05-06

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