ATE340584T1 - Zusammensetzung und verfahren zur behandlung chronischer allograft-abstossung - Google Patents

Zusammensetzung und verfahren zur behandlung chronischer allograft-abstossung

Info

Publication number: ATE340584T1
Authority: AT; Austria
Prior art keywords: composition; allograft rejection; chronic allograft; treating chronic; therapeutically effective
Prior art date: 2001-12-05

Application number

AT02804721T

Other languages

English (en)

Inventor

Daniel R Salomon

Donald V Cramer

Original Assignee

Scripps Research Inst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-05

Filing date

2002-12-05

Publication date

2006-10-15

2002-12-05 Application filed by Scripps Research Inst filed Critical Scripps Research Inst

2006-10-15 Application granted granted Critical

2006-10-15 Publication of ATE340584T1 publication Critical patent/ATE340584T1/de

Links

230000001684 chronic effect Effects 0.000 title abstract 2
PTOAARAWEBMLNO-KVQBGUIXSA-N Cladribine Chemical compound C1=NC=2C(N)=NC(Cl)=NC=2N1[C@H]1C[C@H](O)[C@@H](CO)O1 PTOAARAWEBMLNO-KVQBGUIXSA-N 0.000 abstract 1
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
229930105110 Cyclosporin A Natural products 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
229930182912 cyclosporin Natural products 0.000 abstract 1
239000003018 immunosuppressive agent Substances 0.000 abstract 1
229940124589 immunosuppressive drug Drugs 0.000 abstract 1
210000000056 organ Anatomy 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Surgery (AREA)
Transplantation (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT02804721T 2001-12-05 2002-12-05 Zusammensetzung und verfahren zur behandlung chronischer allograft-abstossung ATE340584T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US10/006,562 US7368423B1 (en)	2001-12-05	2001-12-05	Composition and method for treating chronic allograft rejection

Publications (1)

Publication Number	Publication Date
ATE340584T1 true ATE340584T1 (de)	2006-10-15

Family

ID=21721475

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02804721T ATE340584T1 (de)	2001-12-05	2002-12-05	Zusammensetzung und verfahren zur behandlung chronischer allograft-abstossung

Country Status (13)

Country	Link
US (1)	US7368423B1 (de)
EP (1)	EP1461062B1 (de)
JP (1)	JP2005530680A (de)
AT (1)	ATE340584T1 (de)
AU (1)	AU2002357062B2 (de)
CA (1)	CA2465120A1 (de)
CY (1)	CY1106242T1 (de)
DE (1)	DE60215051T2 (de)
DK (1)	DK1461062T3 (de)
ES (1)	ES2269825T3 (de)
MX (1)	MXPA04005097A (de)
PT (1)	PT1461062E (de)
WO (1)	WO2003049682A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8450281B2 (en)	2007-01-04	2013-05-28	Debiopharm S.A.	Non-immunosuppressive cyclosporin for treatment of Ullrich congenital muscular dystrophy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5310732A (en) *	1986-02-03	1994-05-10	The Scripps Research Institute	2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis
AU7470794A (en) *	1994-05-26	1995-12-21	Scripps Research Institute, The	2-halo-2'-deoxyadenosine treatement for inflammatory bowel disease
AR006514A1 (es) *	1995-07-04	1999-09-08	Sandoz Ag	Un macrolido, sus usos, un proceso para producirlo, un aislado biologicamente puro capaz de producirlo, y una composicion farmaceutica quelo comprende
DE19547648A1 (de) *	1995-12-20	1997-06-26	Hoechst Ag	Zubereitung, enthaltend High Density Lipoproteine und Crotonsäureamidderivate
JPH11228442A (ja) *	1998-02-09	1999-08-24	Cypros Pharmaceut Corp	臓器移植後のシクロスポリン投与量を低減するためのフルクトース二リン酸の使用

2001
- 2001-12-05 US US10/006,562 patent/US7368423B1/en not_active Expired - Fee Related
2002
- 2002-12-05 DE DE60215051T patent/DE60215051T2/de not_active Expired - Lifetime
- 2002-12-05 EP EP02804721A patent/EP1461062B1/de not_active Expired - Lifetime
- 2002-12-05 ES ES02804721T patent/ES2269825T3/es not_active Expired - Lifetime
- 2002-12-05 AU AU2002357062A patent/AU2002357062B2/en not_active Ceased
- 2002-12-05 AT AT02804721T patent/ATE340584T1/de active
- 2002-12-05 DK DK02804721T patent/DK1461062T3/da active
- 2002-12-05 CA CA002465120A patent/CA2465120A1/en not_active Abandoned
- 2002-12-05 PT PT02804721T patent/PT1461062E/pt unknown
- 2002-12-05 WO PCT/US2002/038628 patent/WO2003049682A2/en not_active Ceased
- 2002-12-05 JP JP2003550733A patent/JP2005530680A/ja active Pending
2004
- 2004-05-27 MX MXPA04005097A patent/MXPA04005097A/es active IP Right Grant
2006
- 2006-11-14 CY CY20061101654T patent/CY1106242T1/el unknown

Also Published As

Publication number	Publication date
MXPA04005097A (es)	2004-08-19
HK1064610A1 (en)	2005-02-04
AU2002357062B2 (en)	2007-08-02
ES2269825T3 (es)	2007-04-01
WO2003049682A2 (en)	2003-06-19
WO2003049682A3 (en)	2004-01-15
EP1461062B1 (de)	2006-09-27
DE60215051T2 (de)	2007-05-16
AU2002357062A1 (en)	2003-06-23
JP2005530680A (ja)	2005-10-13
DE60215051D1 (de)	2006-11-09
DK1461062T3 (da)	2007-01-08
EP1461062A2 (de)	2004-09-29
CY1106242T1 (el)	2011-06-08
US7368423B1 (en)	2008-05-06
EP1461062A4 (de)	2005-03-16
PT1461062E (pt)	2006-12-29
CA2465120A1 (en)	2003-06-19

Similar Documents

Publication	Publication Date	Title
NL300056I1 (nl)	2001-12-01	Toepassing van rapamycine en derivaten en vóórgeneesmiddelen daarvan bij de bereiding van een geneesmiddel voor het remmen van de afstoting van een transplantaat in zoogdieren.
NZ527076A (en)	2006-03-31	Graft rejection inhibitors used in combination with immunosuppressants
WO2004100868A3 (en)	2005-07-07	Method of treating transplant rejection
ATE424893T1 (de)	2009-03-15	Behandlung und vorbeugung von insulin- produzierende zelltransplantatabstossung
UA88463C2 (ru)	2009-10-26	Фармацевтическая композиция, которая содержит соединение 1, и процесс лечения вич-инфекции
CY1116107T1 (el)	2017-02-08	Ενωσεις για χρηση στην αγωγη αυτοανοσων παθησεων, ανοσο-αλλεργικων παθησεων και απορριψης μεταμοσχευσης οργανων ή ιστων
ATE276764T1 (de)	2004-10-15	Camptothecin arzneimittelkombinationen mit verringerten nebenwirkungen
EP3530288A3 (de)	2019-12-18	Verfahren zur behandlung von leiden in zusammenhang mit masp-2-abhängiger komplementaktivierung
DE602005025232D1 (de)	2011-01-20	Verwendung von äd-mealaü3-äetvalü4-ciclosporin zur behandlung von hepatitis-c-infektion
CO5700767A2 (es)	2006-11-30	Procedimiento de tratamiento de rechazo de transplantes
DK1539166T3 (da)	2008-10-20	Farmaceutiske sammensætninger indeholdende dextromethorphan og quinidin til behandling af neurologiske sygdomme
ID29393A (id)	2001-08-30	Komposisi pengobatan kanker dan metoda penggunaan minyak-minyak esensil tanaman alamiah
TNSN07304A1 (en)	2008-12-31	Combination of xolair with immunosuppressive agent
IL152316A0 (en)	2003-05-29	Pharmaceutical compositions and kits for treating transplant rejection
DK1545537T3 (da)	2007-07-02	Alfa-7-nikotinreceptoragonister og statiner i kombination
TR200200821T2 (tr)	2002-06-21	5-Beta-sapojenin ve pseudosapojenin türevleri ve bunların bunama tedavisinde kullanımı.
ATE538790T1 (de)	2012-01-15	Scopolamin für die behandlung von depression und ängstlichkeit
DE69008258D1 (de)	1994-05-26	S-adenosylmethionin zur behandlung von pankreatitis und der immunabstossung des pankreastransplantates.
EP1336619A3 (de)	2003-12-10	Kombination eines HVEM-LIGHT-Inhibitors mit einem Immunosuppressor zur Behandlung oder Vorbeugung von Immunkrankheiten
WO2006034001A3 (en)	2006-11-23	Methods of treating hiv infection
ATE297217T1 (de)	2005-06-15	Zusammensetzung zur vorbeugung und behandlung von transplantatabstossung
ATE340584T1 (de)	2006-10-15	Zusammensetzung und verfahren zur behandlung chronischer allograft-abstossung
ATE213233T1 (de)	2002-02-15	Substituierte caprolactame und deren derivate verwendbar zur behandlung der hiv-krankheit
WO2005041877A3 (en)	2005-06-16	Method of inhibiting rejection following organ transplantation
WO2000067773A3 (en)	2001-06-28	Combinations of immunosupressive agents for the treatment or prevention of graft rejections

Legal Events

Date

Code

Title

Description

2007-06-15

UEP

Publication of translation of european patent specification

Ref document number: 1461062

Country of ref document: EP