ATE341337T1 - P-selectin zeilgerichtetenligand und dessen zusammenstezung - Google Patents

P-selectin zeilgerichtetenligand und dessen zusammenstezung

Info

Publication number
ATE341337T1
ATE341337T1 AT04735558T AT04735558T ATE341337T1 AT E341337 T1 ATE341337 T1 AT E341337T1 AT 04735558 T AT04735558 T AT 04735558T AT 04735558 T AT04735558 T AT 04735558T AT E341337 T1 ATE341337 T1 AT E341337T1
Authority
AT
Austria
Prior art keywords
alkyl
group
optionally substituted
moiety
selectin
Prior art date
Application number
AT04735558T
Other languages
English (en)
Inventor
Chantal C M Appeldoorn
Berkel Theodorus Josephus Van
Erik Anna Leonardus Biessen
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Application granted granted Critical
Publication of ATE341337T1 publication Critical patent/ATE341337T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
AT04735558T 2003-05-30 2004-06-01 P-selectin zeilgerichtetenligand und dessen zusammenstezung ATE341337T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20030012123 EP1481683A1 (de) 2003-05-30 2003-05-30 P-Selectin Zeilgerichtetenligand und dessen Zusammenstezung

Publications (1)

Publication Number Publication Date
ATE341337T1 true ATE341337T1 (de) 2006-10-15

Family

ID=33104110

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04735558T ATE341337T1 (de) 2003-05-30 2004-06-01 P-selectin zeilgerichtetenligand und dessen zusammenstezung

Country Status (8)

Country Link
US (1) US8003596B2 (de)
EP (2) EP1481683A1 (de)
JP (1) JP4771291B2 (de)
AT (1) ATE341337T1 (de)
CA (1) CA2527438A1 (de)
DE (1) DE602004002699T2 (de)
ES (1) ES2273260T3 (de)
WO (1) WO2004105783A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5694665B2 (ja) * 2006-11-15 2015-04-01 アースリティス レリーフ プラス エル ティー ディーＡｒｔｈｒｉｔｉｓ Ｒｅｌｉｅｆ Ｐｌｕｓ Ｌｔｄ 局所製剤とその用法
EP2111218B1 (de) * 2007-01-24 2014-07-02 Syddansk Universitet Dna-kontrollierte anordnung von lipidmembranen
ES2919563T3 (es) * 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
JP2016160248A (ja) * 2015-03-05 2016-09-05 国立大学法人京都大学 糖誘導体、またはその塩、セレクチン結合剤、糖結合体、粒子状キャリア、および輸送方法
EP3824906A1 (de) 2016-12-21 2021-05-26 Amgen Inc. Anti-tnf alpha antikörperformulierungen
US12150998B2 (en) 2021-04-20 2024-11-26 Bicycletx Limited Bicyclic peptide ligands specific for P-selectin
CN113616810A (zh) * 2021-08-11 2021-11-09 南开大学 一种靶向p-选择素的工程化细胞外囊泡组合物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6583301B1 (en) 1998-04-08 2003-06-24 Celltech R & D Limited Lipids
GB9919338D0 (en) * 1999-08-16 1999-10-20 Celltech Therapeutics Ltd Biological products
US6656448B1 (en) 2000-02-15 2003-12-02 Bristol-Myers Squibb Pharma Company Matrix metalloproteinase inhibitors
NO20004795D0 (no) * 2000-09-26 2000-09-26 Nycomed Imaging As Peptidbaserte forbindelser
EP1337278A2 (de) 2000-11-27 2003-08-27 Bristol-Myers Squibb Medical Imaging, Inc. Gleichzeitiges imaging der kardialen perfusion und eines auf den vitronektin rezeptor zielgerichteten agens
EP1392756B1 (de) 2001-06-01 2007-02-14 Astellas Pharma Europe B.V. Lipid-polymer konjugaten
EP1288222A1 (de) * 2001-09-03 2003-03-05 Yamanouchi Europe B.V. Selektiv P-Selectin bindende peptidische Verbindungen

Also Published As

Publication number Publication date
DE602004002699D1 (de) 2006-11-16
EP1481683A1 (de) 2004-12-01
WO2004105783A1 (en) 2004-12-09
CA2527438A1 (en) 2004-12-09
EP1638588A1 (de) 2006-03-29
DE602004002699T2 (de) 2007-08-16
US8003596B2 (en) 2011-08-23
EP1638588B1 (de) 2006-10-04
ES2273260T3 (es) 2007-05-01
JP2007500200A (ja) 2007-01-11
US20070185348A1 (en) 2007-08-09
JP4771291B2 (ja) 2011-09-14

Similar Documents

Publication Publication Date Title
Zhang et al. Dynamic covalent polymers for biomedical applications
JP5441693B2 (ja) 新規脂質ペプチド並びにヒドロゲル
Tipper et al. Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine.
KR101895245B1 (ko) 양친매성 선형 펩티드/펩토이드 및 이를 포함하는 히드로겔
WO2006001382A1 (ja) ジペプチドまたはジペプチド誘導体の製造法
Kabiri et al. Toward a mechanistic understanding of ionic self-complementary peptide self-assembly: role of water molecules and ions
MX2011005528A (es) Metodo para producir derivados funcionalizados con acido hialuronico y formacion de sus hidrogeles.
RU2007103811A (ru) Пептидные антибиотики и способы их получения
CN105102469A (zh) 交联的肽水凝胶
JPWO2007000979A1 (ja) 自己組織化ペプチドおよびそれより得られるゲル
DE602004002699D1 (de) P-selectin zeilgerichtetenligand und dessen zusammenstezung
US20220127565A1 (en) A Self-Assembling Short Amphiphilic Peptide And Related Methods And Uses
CA2368824A1 (en) Rapid dehydration of proteins
BRPI0410861A (pt) métodos e composições para a produção de aminoácidos
Beyer et al. Low fouling peptides with an all (D) amino acid sequence provide enhanced stability against proteolytic degradation while maintaining low antifouling properties
PE20070009A1 (es) Tigeciclina y metodos para su preparacion
FR3032202A1 (fr) Matrice sous forme de bille comme support cellulaire
Morton et al. Crosslinker structure modulates bulk mechanical properties and dictates hMSC behavior on hyaluronic acid hydrogels
Knoth et al. The Ras pathway modulator melophlin A targets dynamins
Bernhard et al. Spectrophotometric and structural evidence as to the mechanism of protease catalysis at chemical bonding resolution
O'Donovan et al. A photocleavable linker for the chemoselective functionalization of biomaterials
US20100093084A1 (en) Method for creating intracellular artificial nanostructures in situ
US20220325072A1 (en) Zwitterionic crosslinkers, hydrogels comprising zwitterionic crosslinkers, and methods for making and using
WO2006001381A1 (ja) ジペプチドまたはジペプチド誘導体の製造法
Kirchner et al. Photoswitchable Peptides and Proteins

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties