ATE342353T1 - Abtrennung von plasmin(ogen) aus proteinlösungen - Google Patents

Abtrennung von plasmin(ogen) aus proteinlösungen

Info

Publication number
ATE342353T1
ATE342353T1 AT02740615T AT02740615T ATE342353T1 AT E342353 T1 ATE342353 T1 AT E342353T1 AT 02740615 T AT02740615 T AT 02740615T AT 02740615 T AT02740615 T AT 02740615T AT E342353 T1 ATE342353 T1 AT E342353T1
Authority
AT
Austria
Prior art keywords
plasmin
ogen
amino acid
separation
protein solutions
Prior art date
Application number
AT02740615T
Other languages
English (en)
Inventor
Israel Nur
Liliana Bar
Malkit Azachi
Original Assignee
Omrix Biopharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omrix Biopharm Sa filed Critical Omrix Biopharm Sa
Application granted granted Critical
Publication of ATE342353T1 publication Critical patent/ATE342353T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
AT02740615T 2001-05-21 2002-05-17 Abtrennung von plasmin(ogen) aus proteinlösungen ATE342353T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29196801P 2001-05-21 2001-05-21
EP01115157 2001-06-21

Publications (1)

Publication Number Publication Date
ATE342353T1 true ATE342353T1 (de) 2006-11-15

Family

ID=26076623

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02740615T ATE342353T1 (de) 2001-05-21 2002-05-17 Abtrennung von plasmin(ogen) aus proteinlösungen

Country Status (19)

Country Link
US (4) US20040197891A1 (de)
EP (1) EP1390485B1 (de)
JP (1) JP4385097B2 (de)
KR (1) KR100871454B1 (de)
AT (1) ATE342353T1 (de)
AU (1) AU2002314081B2 (de)
CA (1) CA2447789C (de)
CZ (1) CZ20033097A3 (de)
DE (1) DE60215338T2 (de)
EE (1) EE05485B1 (de)
ES (1) ES2274044T3 (de)
HU (1) HU228899B1 (de)
IL (2) IL158754A0 (de)
MX (1) MXPA03010616A (de)
PL (1) PL205685B1 (de)
RU (2) RU2344143C2 (de)
SK (1) SK288005B6 (de)
WO (1) WO2002095019A1 (de)
ZA (1) ZA200309030B (de)

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CN107406840B (zh) 2015-02-25 2021-05-28 奥姆里克斯生物药品有限公司 用于纯化和定量凝血酶及其降解多肽的方法
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US10159720B2 (en) 2015-12-08 2018-12-25 Omrix Biopharmaceuticals Ltd Thrombin microcapsules, preparation and uses thereof
JP6949839B2 (ja) 2015-11-11 2021-10-13 エシコン・インコーポレイテッドＥｔｈｉｃｏｎ， Ｉｎｃ． シーラント配合物及びその使用
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CA3035650A1 (en) * 2016-09-01 2018-03-08 Plas-Free Ltd Human blood-derived products having decreased fibrinolytic activity and uses thereof in hemostatic disorders
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IL247821A0 (en) 2016-09-14 2017-01-31 Omrix Biopharmaceuticals Ltd Adhesive preparations and their use
KR102640024B1 (ko) * 2017-03-09 2024-02-22 프리비파하르마, 컨설팅 게엠베하 혈액 분획으로부터의 Glu-플라스미노겐의 제조 및 용도
IL256405A (en) 2017-12-19 2018-01-31 Omrix Biopharmaceuticals Ltd Wound bandage and method for its production
ES2983341T3 (es) * 2018-02-28 2024-10-22 Plas Free Ltd Dispositivo extracorpóreo y matriz para la eliminación de proteínas fibrinolíticas de fluidos biológicos, métodos y usos de los mismos
IL263679A (en) 2018-12-12 2019-03-31 Omrix Biopharmaceuticals Ltd Kits, methods, and compositions for preventing tissue adhesion
WO2020121290A1 (en) 2018-12-12 2020-06-18 Omrix Biopharmaceuticals Ltd. High concentrated protein compositions for preventing tissue adhesion
CN111760556B (zh) * 2020-07-09 2023-06-30 江苏尤里卡生物科技有限公司 一种尿激酶吸附剂及其制备方法和应用
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JP2024534444A (ja) 2021-09-16 2024-09-20 エシコン・インコーポレイテッド 組織経路封止用組成物のためのキット
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Also Published As

Publication number Publication date
EP1390485A1 (de) 2004-02-25
IL158754A0 (en) 2004-05-12
US7641918B2 (en) 2010-01-05
IL158754A (en) 2009-05-04
JP4385097B2 (ja) 2009-12-16
PL365808A1 (en) 2005-01-10
DE60215338D1 (de) 2006-11-23
AU2002314081B2 (en) 2007-04-05
CA2447789C (en) 2012-11-06
US20030124703A1 (en) 2003-07-03
RU2344143C2 (ru) 2009-01-20
WO2002095019A1 (en) 2002-11-28
EE05485B1 (et) 2011-10-17
RU2003136746A (ru) 2005-05-20
HUP0600110A2 (en) 2006-05-29
KR100871454B1 (ko) 2008-12-03
ES2274044T3 (es) 2007-05-16
PL205685B1 (pl) 2010-05-31
HK1060902A1 (en) 2004-08-27
JP2004528853A (ja) 2004-09-24
US8563288B2 (en) 2013-10-22
SK14202003A3 (sk) 2004-08-03
US7125569B2 (en) 2006-10-24
HUP0600110A3 (en) 2010-01-28
CA2447789A1 (en) 2002-11-28
US20040197891A1 (en) 2004-10-07
RU2458067C2 (ru) 2012-08-10
US20070092959A1 (en) 2007-04-26
SK288005B6 (sk) 2012-10-02
EE200300578A (et) 2004-02-16
RU2008130356A (ru) 2010-01-27
HU228899B1 (en) 2013-06-28
KR20040011503A (ko) 2004-02-05
DE60215338T2 (de) 2007-05-16
MXPA03010616A (es) 2004-04-02
ZA200309030B (en) 2005-06-29
CZ20033097A3 (cs) 2004-06-16
EP1390485B1 (de) 2006-10-11
US20090176293A1 (en) 2009-07-09

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