ATE342997T1 - Herpesvirus saimiri als viraler vektor - Google Patents

Herpesvirus saimiri als viraler vektor

Info

Publication number
ATE342997T1
ATE342997T1 AT97919133T AT97919133T ATE342997T1 AT E342997 T1 ATE342997 T1 AT E342997T1 AT 97919133 T AT97919133 T AT 97919133T AT 97919133 T AT97919133 T AT 97919133T AT E342997 T1 ATE342997 T1 AT E342997T1
Authority
AT
Austria
Prior art keywords
herpesvirus saimiri
viral vector
genes
essential
viral
Prior art date
Application number
AT97919133T
Other languages
English (en)
Inventor
David Mark Meredith
Alexander Fred Markham
Original Assignee
Univ Leeds
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leeds filed Critical Univ Leeds
Application granted granted Critical
Publication of ATE342997T1 publication Critical patent/ATE342997T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16411Rhadinovirus, e.g. human herpesvirus 8
    • C12N2710/16422New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16411Rhadinovirus, e.g. human herpesvirus 8
    • C12N2710/16441Use of virus, viral particle or viral elements as a vector
    • C12N2710/16443Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT97919133T 1996-09-04 1997-09-04 Herpesvirus saimiri als viraler vektor ATE342997T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9618477.5A GB9618477D0 (en) 1996-09-04 1996-09-04 Gene therapy

Publications (1)

Publication Number Publication Date
ATE342997T1 true ATE342997T1 (de) 2006-11-15

Family

ID=10799414

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97919133T ATE342997T1 (de) 1996-09-04 1997-09-04 Herpesvirus saimiri als viraler vektor

Country Status (18)

Country Link
US (1) US6379967B1 (de)
EP (1) EP0939828B1 (de)
JP (1) JP2000517191A (de)
KR (1) KR20000068461A (de)
CN (1) CN1237209A (de)
AT (1) ATE342997T1 (de)
AU (1) AU737197B2 (de)
BR (1) BR9711998A (de)
CA (1) CA2264956A1 (de)
CZ (1) CZ69799A3 (de)
DE (1) DE69736838T2 (de)
ES (1) ES2274541T3 (de)
GB (1) GB9618477D0 (de)
HU (1) HUP9904329A3 (de)
IL (1) IL128635A0 (de)
NZ (1) NZ334323A (de)
SG (1) SG91252A1 (de)
WO (1) WO1998010083A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9826069D0 (en) 1998-11-28 1999-01-20 Univ Leeds HIV vaccine
GB9903694D0 (en) * 1999-02-19 1999-04-14 Univ Leeds Latency-associated regulatory region
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US7829084B2 (en) * 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
JP2005532829A (ja) * 2002-07-18 2005-11-04 インヴィトロジェン コーポレーション 組換え部位を含むウイルスベクター
WO2005014796A2 (en) 2003-08-08 2005-02-17 Invitrogen Corporation Methods and compositions for seamless cloning of nucleic acid molecules
WO2005054438A2 (en) 2003-12-01 2005-06-16 Invitrogen Corporation Nucleic acid molecules containing recombination sites and methods of using the same
RU2423381C2 (ru) * 2005-07-25 2011-07-10 Трабьон Фармасьютикалз, Инк. Снижение количества в-клеток с использованием cd37-специфических и cd20-специфических связывающих молекул
NZ573646A (en) * 2006-06-12 2012-04-27 Wyeth Llc Single-chain multivalent binding proteins with effector function
JP2010532764A (ja) * 2007-07-06 2010-10-14 トゥルビオン・ファーマシューティカルズ・インコーポレーテッド C末端に配置された特異的結合性ドメインを有する結合性ペプチド
RU2531754C2 (ru) * 2008-04-11 2014-10-27 ЭМЕРДЖЕНТ ПРОДАКТ ДИВЕЛОПМЕНТ СИЭТЛ,ЭлЭлСи,US Связывающееся с cd37 иммунотерапевтическое средство и его комбинация с бифункциональным химиотерапевтическим средством
WO2017053469A2 (en) 2015-09-21 2017-03-30 Aptevo Research And Development Llc Cd3 binding polypeptides
US11149255B2 (en) * 2016-09-06 2021-10-19 Bioventures, Llc Compositions and methods for generating reversion free attenuated and/or replication incompetent vaccine vectors
CN107653345B (zh) * 2017-11-08 2021-04-27 中国人民解放军军事医学科学院野战输血研究所 猴b病毒实时荧光定量pcr方法及其通用引物、mgb探针与试剂盒
RU2771081C2 (ru) * 2020-08-25 2022-04-26 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Рекомбинантный штамм Herpesvirus saimiri для получения популяций иммортализованных аутологичных Т-лимфоцитов, экспрессирующих парные химерные рецепторы против опухолевых антигенов CD44 и CD133

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672344A (en) * 1987-12-30 1997-09-30 The Regents Of The University Of Michigan Viral-mediated gene transfer system
AU4408889A (en) * 1988-10-06 1990-05-01 Behringwerke Aktiengesellschaft H. saimiri-htlv-x region vector
DE3834157A1 (de) * 1988-10-07 1990-04-19 Behringwerke Ag Selektionierbare vektoren fuer humane t-zellen

Also Published As

Publication number Publication date
US6379967B1 (en) 2002-04-30
NZ334323A (en) 2000-06-23
SG91252A1 (en) 2002-09-17
KR20000068461A (ko) 2000-11-25
HUP9904329A3 (en) 2002-01-28
AU737197B2 (en) 2001-08-09
ES2274541T3 (es) 2007-05-16
HUP9904329A2 (hu) 2000-04-28
EP0939828B1 (de) 2006-10-18
CN1237209A (zh) 1999-12-01
DE69736838D1 (de) 2006-11-30
AU4307197A (en) 1998-03-26
EP0939828A1 (de) 1999-09-08
JP2000517191A (ja) 2000-12-26
IL128635A0 (en) 2000-01-31
GB9618477D0 (en) 1996-10-16
CZ69799A3 (cs) 1999-08-11
CA2264956A1 (en) 1998-03-12
WO1998010083A1 (en) 1998-03-12
BR9711998A (pt) 2000-01-18
DE69736838T2 (de) 2007-10-31

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