ATE344022T1 - Proinsulin c-peptid enthaltende arzneizubereitung mit verzögerter wirkstofffreigabe - Google Patents

Proinsulin c-peptid enthaltende arzneizubereitung mit verzögerter wirkstofffreigabe

Info

Publication number: ATE344022T1
Authority: AT; Austria
Prior art keywords: peptide; proinsulin; delayed release; preparation containing; medicinal preparation
Prior art date: 2000-11-10

Application number

AT01980762T

Other languages

English (en)

Inventor

Detlef Mohr

Tim Seiffert

Original Assignee

Creative Peptides Sweden Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-10

Filing date

2001-11-08

Publication date

2006-11-15

2001-11-08 Application filed by Creative Peptides Sweden Ab filed Critical Creative Peptides Sweden Ab

2006-11-15 Application granted granted Critical

2006-11-15 Publication of ATE344022T1 publication Critical patent/ATE344022T1/de

Links

VOUAQYXWVJDEQY-QENPJCQMSA-N 33017-11-7 Chemical compound OC(=O)CC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O)CCC1 VOUAQYXWVJDEQY-QENPJCQMSA-N 0.000 title abstract 4
108010075254 C-Peptide Proteins 0.000 title abstract 4
230000003111 delayed effect Effects 0.000 title abstract 4
238000009472 formulation Methods 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 3
206010012601 diabetes mellitus Diseases 0.000 abstract 1
239000011159 matrix material Substances 0.000 abstract 1
239000011859 microparticle Substances 0.000 abstract 1
229920000642 polymer Polymers 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Immunology (AREA)
Cardiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Ophthalmology & Optometry (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT01980762T 2000-11-10 2001-11-08 Proinsulin c-peptid enthaltende arzneizubereitung mit verzögerter wirkstofffreigabe ATE344022T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10055857A DE10055857A1 (de)	2000-11-10	2000-11-10	Neue pharmazeutische Depotformulierung

Publications (1)

Publication Number	Publication Date
ATE344022T1 true ATE344022T1 (de)	2006-11-15

Family

ID=7662892

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01980762T ATE344022T1 (de)	2000-11-10	2001-11-08	Proinsulin c-peptid enthaltende arzneizubereitung mit verzögerter wirkstofffreigabe

Country Status (9)

Country	Link
US (1)	US20040053817A1 (de)
EP (1)	EP1337243B1 (de)
JP (1)	JP2004513143A (de)
AT (1)	ATE344022T1 (de)
AU (2)	AU1255002A (de)
CA (1)	CA2428159A1 (de)
DE (2)	DE10055857A1 (de)
NZ (1)	NZ526162A (de)
WO (1)	WO2002038129A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0022342D0 (en) *	2000-09-12	2000-10-25	Creative Peptides Sweden Ab	Reduction of the electrocardiographic QT interval
US20040071780A1 (en) *	2002-01-16	2004-04-15	Lillard James W.	PACE-A microspheres for delivery of antigens
KR20100107083A (ko) *	2002-12-17	2010-10-04	메디뮨 엘엘씨	생물활성 물질의 고압 분무 건조
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
GB0323979D0 (en) *	2003-10-13	2003-11-19	Creative Peptides Sweden Ab	Therapeutic applications for c-peptide
JP5105578B2 (ja)	2003-11-05	2012-12-26	サーコードバイオサイエンスインコーポレイテッド	細胞接着のモジュレーター
US8168655B2 (en)	2005-05-17	2012-05-01	Sarcode Bioscience Inc.	Compositions and methods for treatment of eye disorders
GB0511269D0 (en)	2005-06-02	2005-07-13	Creative Peptides Sweden Ab	Sustained release preparation of pro-insulin C-peptide
KR20140107691A (ko) *	2006-03-20	2014-09-04	버텍스 파마슈티칼스 인코포레이티드	의약 조성물
ES2331342B1 (es) *	2006-05-22	2010-10-13	Consejo Superior Investg.Cientificas	Uso de la proinsulina para la elaboracion de una composicion farmaceutica neuroprotectora, composicion terapeutica que la contiene y sus aplicaciones.
WO2008118387A2 (en) *	2007-03-23	2008-10-02	Wayne State University	Erythrocyte atp-release modulators
MX2009013293A (es)	2007-06-04	2010-02-15	Synergy Pharmaceuticals Inc	Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos.
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
MX2010004281A (es)	2007-10-19	2010-09-10	Sarcode Corp	Composiciones y metodos para el tratamiento de la retinopatia diabetica.
WO2009139817A2 (en)	2008-04-15	2009-11-19	Sarcode Corporation	Crystalline pharmaceutical and methods of preparation and use thereof
EP2810951B1 (de)	2008-06-04	2017-03-15	Synergy Pharmaceuticals Inc.	Für die Behandlung von gastrointestinalen Erkrankungen, Entzündungen, Krebs und anderen Erkrankungen geeignete Agonisten von Guanylatcyclase
CA2730603C (en)	2008-07-16	2019-09-24	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8378105B2 (en)	2009-10-21	2013-02-19	Sarcode Bioscience Inc.	Crystalline pharmaceutical and methods of preparation and use thereof
NZ603399A (en)	2010-05-17	2014-09-26	Cebix Inc	Pegylated c-peptide
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
SI3715345T1 (sl)	2012-07-25	2024-07-31	Bausch + Lomb Ireland Limited	Priprava zaviralca lfa-1
EP3718557A3 (de)	2013-02-25	2020-10-21	Bausch Health Ireland Limited	Guanylat-cyclase-rezeptoragonist sp-333 zur verwendung in der darmreinigung
JP2016514670A (ja)	2013-03-15	2016-05-23	シナジーファーマシューティカルズインコーポレイテッド	他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
JP2016514671A (ja)	2013-03-15	2016-05-23	シナジーファーマシューティカルズインコーポレイテッド	グアニル酸シクラーゼのアゴニストおよびその使用
WO2015054649A2 (en)	2013-10-10	2015-04-16	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of opioid induced dysfunctions
JP2019506383A (ja)	2016-01-11	2019-03-07	シナジーファーマシューティカルズインコーポレイテッド	潰瘍性大腸炎を治療するための製剤および方法
KR102371699B1 (ko) *	2019-12-17	2022-03-08	한국전자기술연구원	당뇨 추정 시스템 및 그 방법
CN116803378B (zh) *	2023-08-24	2023-11-17	北京福元医药股份有限公司	一种格列齐特缓释片剂及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4652548A (en) *	1981-08-27	1987-03-24	Eli Lilly And Company	Pharmaceutical formulations comprising human insulin, human C-peptide, and human proinsulin
KR100225983B1 (ko) *	1992-10-26	1999-10-15	클라우스-디터 홈메리히, 디트리히 빌헬름 샤흐트	마이크로캡슐의 제조 방법
DE4406172C2 (de) *	1994-02-25	2003-10-02	Sanol Arznei Schwarz Gmbh	Polyester
US5942253A (en) *	1995-10-12	1999-08-24	Immunex Corporation	Prolonged release of GM-CSF
SE520392C2 (sv) *	1996-09-27	2003-07-01	Creative Peptides Sweden Ab C	Specifika peptider för behandling av diabetes mellitus
DE10041478A1 (de) *	2000-08-24	2002-03-14	Sanol Arznei Schwarz Gmbh	Neue pharmazeutische Zusammensetzung
GB0022342D0 (en) *	2000-09-12	2000-10-25	Creative Peptides Sweden Ab	Reduction of the electrocardiographic QT interval
SE517421C2 (sv) *	2000-10-06	2002-06-04	Bioglan Ab	Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav
DE10055742B4 (de) *	2000-11-10	2006-05-11	Schwarz Pharma Ag	Neue Polyester, Verfahren zu ihrer Herstellung und aus den Polyestern hergestellte Depot-Arzneiformen
SE0201599D0 (sv) *	2002-03-21	2002-05-30	Skyepharma Ab	Microparticles

2000
- 2000-11-10 DE DE10055857A patent/DE10055857A1/de not_active Withdrawn
2001
- 2001-11-08 US US10/416,173 patent/US20040053817A1/en not_active Abandoned
- 2001-11-08 NZ NZ526162A patent/NZ526162A/en unknown
- 2001-11-08 AT AT01980762T patent/ATE344022T1/de not_active IP Right Cessation
- 2001-11-08 AU AU1255002A patent/AU1255002A/xx active Pending
- 2001-11-08 DE DE60124294T patent/DE60124294D1/de not_active Expired - Fee Related
- 2001-11-08 AU AU2002212550A patent/AU2002212550B2/en not_active Ceased
- 2001-11-08 JP JP2002540719A patent/JP2004513143A/ja active Pending
- 2001-11-08 EP EP01980762A patent/EP1337243B1/de not_active Expired - Lifetime
- 2001-11-08 CA CA002428159A patent/CA2428159A1/en not_active Abandoned
- 2001-11-08 WO PCT/GB2001/004980 patent/WO2002038129A2/en not_active Ceased

Also Published As

Publication number	Publication date
DE60124294D1 (de)	2006-12-14
WO2002038129A3 (en)	2003-02-13
DE10055857A1 (de)	2002-08-22
EP1337243B1 (de)	2006-11-02
JP2004513143A (ja)	2004-04-30
WO2002038129A2 (en)	2002-05-16
AU2002212550B2 (en)	2005-08-04
AU1255002A (en)	2002-05-21
NZ526162A (en)	2005-01-28
CA2428159A1 (en)	2002-05-16
US20040053817A1 (en)	2004-03-18
EP1337243A2 (de)	2003-08-27

Legal Events

Date	Code	Title	Description
2007-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE60124294D1 (de)	2006-12-14	Proinsulin c-peptid enthaltende arzneizubereitung mit verzögerter wirkstofffreigabe
UA29563C2 (uk)	2000-11-15	Мікрокапсула для тривалого вивільнення фізіологічно активного пептиду
SV2004001556A (es)	2004-03-08	Preparaciones acidas de insulina con establidad mejorada
AU2003274681A1 (en)	2004-02-23	Dosage form comprising high dose high soluble active ingredient as modified release and low dose active ingredient as immediate release
BR0110573A (pt)	2003-04-01	Composto, composição farmacêutica que compreende esse composto, processo para a preparação de uma composição farmacêutica, utilização do composto e processo para o tratamento profilático ou terapêutico e para a preparação do composto
BR9406363A (pt)	1996-02-27	Composiçao farmacêutica processo para a preparaçao da mesma uso da mesma e processo para o tratamento de doenças relacionadas com o ácido gástrico
BR0116169A (pt)	2003-12-23	Composto, composição farmacêutica que compreende esse composto, processo para a preparação de uma composição farmacêutica, utilização dos compostos, processo para o tratamento profilático ou terapêutico de diabetes do tipo ii e processo para a preparação do composto.
BG66093B1 (bg)	2011-04-29	Състави с контролирано освобождаване, съдържащи нимесулид
DK0954314T3 (da)	2002-02-18	Doseringsformer til bedring af mandlig erektionsdefekt
MY124695A (en)	2006-06-30	Novel composition and use.
CY1105120T1 (el)	2010-03-03	Η αντιμετωπιση αναπνευστικων νοσων
MY127797A (en)	2006-12-29	3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol-containing pharmaceutical composition with slow release of active indgredient
MX9204268A (es)	1994-03-31	Una composicion para la liberacion prolongada y controlada de substancias medicamentosas y un proceso para preparar la misma.
HRP20060147B1 (hr)	2014-02-14	Terapijski sustav s kontroliranim otpuštanjem za nazalnu primjenu
CY1110287T1 (el)	2015-01-14	Χρηση της ανθρωπινης παραθυρεοειδους ορμονης
MX2007006212A (es)	2007-07-09	Medicamento oral para liberacion modificada de al menos un principio activo bajo forma multimicrocapsular.
ATE78157T1 (de)	1992-08-15	Arzneimittel mit langsamer freisetzung.
ATE529097T1 (de)	2011-11-15	Pharmazeutische zubereitung in form einer paste mit einem säurelabilen wirkstoff
BR0014142A (pt)	2002-07-02	Composição de vacina e método de empregar a mesma
BR0211198A (pt)	2004-08-10	Composições farmacêuticas e seu uso
ATE260650T1 (de)	2004-03-15	Orale darreichungsformen zur verabreichung einer fixen kombination von tramadol und diclofenac
WO2002030467A3 (en)	2002-10-24	Pharmaceutical composition containing honey for the treatment of wounds
DE69419365D1 (de)	1999-08-12	Arzneizusammensetzung mit verzögerter Wirkstoffabgabe enthaltend eine Gallensäure als Wirkstoff
TW200505436A (en)	2005-02-16	Modified release pharmaceutical compositions and the processes for preparing them
EA200501223A1 (ru)	2006-04-28	Терапевтическая система, содержащая амоксициллин и клавулановую кислоту