ATE344022T1 - Proinsulin c-peptid enthaltende arzneizubereitung mit verzögerter wirkstofffreigabe - Google Patents

Proinsulin c-peptid enthaltende arzneizubereitung mit verzögerter wirkstofffreigabe

Info

Publication number: ATE344022T1
Authority: AT; Austria
Prior art keywords: peptide; proinsulin; delayed release; preparation containing; medicinal preparation
Prior art date: 2000-11-10

Application number

AT01980762T

Other languages

English (en)

Inventor

Detlef Mohr

Tim Seiffert

Original Assignee

Creative Peptides Sweden Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-10

Filing date

2001-11-08

Publication date

2006-11-15

2001-11-08 Application filed by Creative Peptides Sweden Ab filed Critical Creative Peptides Sweden Ab

2006-11-15 Application granted granted Critical

2006-11-15 Publication of ATE344022T1 publication Critical patent/ATE344022T1/de

Links

VOUAQYXWVJDEQY-QENPJCQMSA-N 33017-11-7 Chemical compound OC(=O)CC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O)CCC1 VOUAQYXWVJDEQY-QENPJCQMSA-N 0.000 title abstract 4
108010075254 C-Peptide Proteins 0.000 title abstract 4
230000003111 delayed effect Effects 0.000 title abstract 4
238000009472 formulation Methods 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 3
206010012601 diabetes mellitus Diseases 0.000 abstract 1
239000011159 matrix material Substances 0.000 abstract 1
239000011859 microparticle Substances 0.000 abstract 1
229920000642 polymer Polymers 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Zoology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Vascular Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Emergency Medicine (AREA)
Biomedical Technology (AREA)
Ophthalmology & Optometry (AREA)
Hematology (AREA)
Obesity (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT01980762T 2000-11-10 2001-11-08 Proinsulin c-peptid enthaltende arzneizubereitung mit verzögerter wirkstofffreigabe ATE344022T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10055857A DE10055857A1 (de)	2000-11-10	2000-11-10	Neue pharmazeutische Depotformulierung

Publications (1)

Publication Number	Publication Date
ATE344022T1 true ATE344022T1 (de)	2006-11-15

Family

ID=7662892

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01980762T ATE344022T1 (de)	2000-11-10	2001-11-08	Proinsulin c-peptid enthaltende arzneizubereitung mit verzögerter wirkstofffreigabe

Country Status (9)

Country	Link
US (1)	US20040053817A1 (de)
EP (1)	EP1337243B1 (de)
JP (1)	JP2004513143A (de)
AT (1)	ATE344022T1 (de)
AU (2)	AU1255002A (de)
CA (1)	CA2428159A1 (de)
DE (2)	DE10055857A1 (de)
NZ (1)	NZ526162A (de)
WO (1)	WO2002038129A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0022342D0 (en) *	2000-09-12	2000-10-25	Creative Peptides Sweden Ab	Reduction of the electrocardiographic QT interval
AU2003205106A1 (en) *	2002-01-16	2003-09-02	Agency For Disease Diagnosis And Prevention	Pace-a microspheres for delivery of antigens
KR20050088175A (ko) *	2002-12-17	2005-09-02	메드이뮨 백신즈 인코포레이티드	생물활성 물질의 고압 분무 건조
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
GB0323979D0 (en)	2003-10-13	2003-11-19	Creative Peptides Sweden Ab	Therapeutic applications for c-peptide
AU2004287875B2 (en)	2003-11-05	2011-06-02	Bausch + Lomb Ireland Limited	Modulators of cellular adhesion
SI1881823T1 (sl)	2005-05-17	2015-04-30	Sarcode Bioscience Inc.	Sestavki in postopki za zdravljenje bolezni oäśesa
GB0511269D0 (en) *	2005-06-02	2005-07-13	Creative Peptides Sweden Ab	Sustained release preparation of pro-insulin C-peptide
WO2007109605A2 (en) *	2006-03-20	2007-09-27	Vertex Pharmaceuticals Incorporated	Pharmaceutical compositions
ES2331342B1 (es) *	2006-05-22	2010-10-13	Consejo Superior Investg.Cientificas	Uso de la proinsulina para la elaboracion de una composicion farmaceutica neuroprotectora, composicion terapeutica que la contiene y sus aplicaciones.
WO2008118387A2 (en) *	2007-03-23	2008-10-02	Wayne State University	Erythrocyte atp-release modulators
WO2008151257A2 (en)	2007-06-04	2008-12-11	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2702984C (en)	2007-10-19	2017-04-11	Sarcode Corporation	Compositions and methods for treatment of diabetic retinopathy
WO2009139817A2 (en)	2008-04-15	2009-11-19	Sarcode Corporation	Crystalline pharmaceutical and methods of preparation and use thereof
ES2627848T3 (es)	2008-06-04	2017-07-31	Synergy Pharmaceuticals Inc.	Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
ES2624828T3 (es)	2008-07-16	2017-07-17	Synergy Pharmaceuticals Inc.	Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US8378105B2 (en)	2009-10-21	2013-02-19	Sarcode Bioscience Inc.	Crystalline pharmaceutical and methods of preparation and use thereof
JP2013533217A (ja)	2010-05-17	2013-08-22	セビックス・インコーポレイテッド	Ｐｅｇ化ｃ−ペプチド
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
EP2877465A4 (de)	2012-07-25	2016-05-11	Sarcode Bioscience Inc	Lfa-1-hemmer und polymorph davon
EP2958577A2 (de)	2013-02-25	2015-12-30	Synergy Pharmaceuticals Inc.	Guanylat-cyclase-rezeptoragonisten zur verwendung bei der darmreinigung
US9708367B2 (en)	2013-03-15	2017-07-18	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase and their uses
EP2968439A2 (de)	2013-03-15	2016-01-20	Synergy Pharmaceuticals Inc.	Zusammensetzungen zur behandlung von magen-darm-störungen
CA2926691A1 (en)	2013-10-10	2015-04-16	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of opioid induced dysfunctions
EP3402804A1 (de)	2016-01-11	2018-11-21	Synergy Pharmaceuticals Inc.	Formulierungen und verfahren zur behandlung von colitis ulcerosa
KR102371699B1 (ko) *	2019-12-17	2022-03-08	한국전자기술연구원	당뇨 추정 시스템 및 그 방법
CN116803378B (zh) *	2023-08-24	2023-11-17	北京福元医药股份有限公司	一种格列齐特缓释片剂及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4652548A (en) *	1981-08-27	1987-03-24	Eli Lilly And Company	Pharmaceutical formulations comprising human insulin, human C-peptide, and human proinsulin
ES2127835T3 (es) *	1992-10-26	1999-05-01	Sanol Arznei Schwarz Gmbh	Procedimiento para la preparacion de microcapsulas.
DE4406172C2 (de) *	1994-02-25	2003-10-02	Sanol Arznei Schwarz Gmbh	Polyester
US5942253A (en) *	1995-10-12	1999-08-24	Immunex Corporation	Prolonged release of GM-CSF
SE520392C2 (sv) *	1996-09-27	2003-07-01	Creative Peptides Sweden Ab C	Specifika peptider för behandling av diabetes mellitus
DE10041478A1 (de) *	2000-08-24	2002-03-14	Sanol Arznei Schwarz Gmbh	Neue pharmazeutische Zusammensetzung
GB0022342D0 (en) *	2000-09-12	2000-10-25	Creative Peptides Sweden Ab	Reduction of the electrocardiographic QT interval
SE517421C2 (sv) *	2000-10-06	2002-06-04	Bioglan Ab	Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav
DE10055742B4 (de) *	2000-11-10	2006-05-11	Schwarz Pharma Ag	Neue Polyester, Verfahren zu ihrer Herstellung und aus den Polyestern hergestellte Depot-Arzneiformen
SE0201599D0 (sv) *	2002-03-21	2002-05-30	Skyepharma Ab	Microparticles

2000
- 2000-11-10 DE DE10055857A patent/DE10055857A1/de not_active Withdrawn
2001
- 2001-11-08 WO PCT/GB2001/004980 patent/WO2002038129A2/en not_active Ceased
- 2001-11-08 AT AT01980762T patent/ATE344022T1/de not_active IP Right Cessation
- 2001-11-08 AU AU1255002A patent/AU1255002A/xx active Pending
- 2001-11-08 AU AU2002212550A patent/AU2002212550B2/en not_active Ceased
- 2001-11-08 DE DE60124294T patent/DE60124294D1/de not_active Expired - Fee Related
- 2001-11-08 NZ NZ526162A patent/NZ526162A/en unknown
- 2001-11-08 EP EP01980762A patent/EP1337243B1/de not_active Expired - Lifetime
- 2001-11-08 US US10/416,173 patent/US20040053817A1/en not_active Abandoned
- 2001-11-08 CA CA002428159A patent/CA2428159A1/en not_active Abandoned
- 2001-11-08 JP JP2002540719A patent/JP2004513143A/ja active Pending

Also Published As

Publication number	Publication date
AU2002212550B2 (en)	2005-08-04
EP1337243B1 (de)	2006-11-02
JP2004513143A (ja)	2004-04-30
WO2002038129A2 (en)	2002-05-16
NZ526162A (en)	2005-01-28
EP1337243A2 (de)	2003-08-27
AU1255002A (en)	2002-05-21
US20040053817A1 (en)	2004-03-18
CA2428159A1 (en)	2002-05-16
DE60124294D1 (de)	2006-12-14
WO2002038129A3 (en)	2003-02-13
DE10055857A1 (de)	2002-08-22

Legal Events

Date	Code	Title	Description
2007-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE60124294D1 (de)	2006-12-14	Proinsulin c-peptid enthaltende arzneizubereitung mit verzögerter wirkstofffreigabe
UA29563C2 (uk)	2000-11-15	Мікрокапсула для тривалого вивільнення фізіологічно активного пептиду
SV2004001556A (es)	2004-03-08	Preparaciones acidas de insulina con establidad mejorada
AU2003274681A1 (en)	2004-02-23	Dosage form comprising high dose high soluble active ingredient as modified release and low dose active ingredient as immediate release
BR0110573A (pt)	2003-04-01	Composto, composição farmacêutica que compreende esse composto, processo para a preparação de uma composição farmacêutica, utilização do composto e processo para o tratamento profilático ou terapêutico e para a preparação do composto
BR9406363A (pt)	1996-02-27	Composiçao farmacêutica processo para a preparaçao da mesma uso da mesma e processo para o tratamento de doenças relacionadas com o ácido gástrico
BR0116169A (pt)	2003-12-23	Composto, composição farmacêutica que compreende esse composto, processo para a preparação de uma composição farmacêutica, utilização dos compostos, processo para o tratamento profilático ou terapêutico de diabetes do tipo ii e processo para a preparação do composto.
BG66093B1 (bg)	2011-04-29	Състави с контролирано освобождаване, съдържащи нимесулид
DK0954314T3 (da)	2002-02-18	Doseringsformer til bedring af mandlig erektionsdefekt
MY124695A (en)	2006-06-30	Novel composition and use.
CY1105120T1 (el)	2010-03-03	Η αντιμετωπιση αναπνευστικων νοσων
MY127797A (en)	2006-12-29	3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol-containing pharmaceutical composition with slow release of active indgredient
MX9204268A (es)	1994-03-31	Una composicion para la liberacion prolongada y controlada de substancias medicamentosas y un proceso para preparar la misma.
HRP20060147B1 (hr)	2014-02-14	Terapijski sustav s kontroliranim otpuštanjem za nazalnu primjenu
CY1110287T1 (el)	2015-01-14	Χρηση της ανθρωπινης παραθυρεοειδους ορμονης
MX2007006212A (es)	2007-07-09	Medicamento oral para liberacion modificada de al menos un principio activo bajo forma multimicrocapsular.
ATE78157T1 (de)	1992-08-15	Arzneimittel mit langsamer freisetzung.
ATE529097T1 (de)	2011-11-15	Pharmazeutische zubereitung in form einer paste mit einem säurelabilen wirkstoff
BR0014142A (pt)	2002-07-02	Composição de vacina e método de empregar a mesma
BR0211198A (pt)	2004-08-10	Composições farmacêuticas e seu uso
ATE260650T1 (de)	2004-03-15	Orale darreichungsformen zur verabreichung einer fixen kombination von tramadol und diclofenac
WO2002030467A3 (en)	2002-10-24	Pharmaceutical composition containing honey for the treatment of wounds
DE69419365D1 (de)	1999-08-12	Arzneizusammensetzung mit verzögerter Wirkstoffabgabe enthaltend eine Gallensäure als Wirkstoff
TW200505436A (en)	2005-02-16	Modified release pharmaceutical compositions and the processes for preparing them
EA200501223A1 (ru)	2006-04-28	Терапевтическая система, содержащая амоксициллин и клавулановую кислоту