ATE344270T1 - Neue 3-decladinosyl-9a-n-carbamoyl- und 9a-n- thiocarbamoylderivate von 9-deoxo-9-dihydro-9a- aza-9a-homoerythromycin a - Google Patents

Neue 3-decladinosyl-9a-n-carbamoyl- und 9a-n- thiocarbamoylderivate von 9-deoxo-9-dihydro-9a- aza-9a-homoerythromycin a

Info

Publication number
ATE344270T1
ATE344270T1 AT04732143T AT04732143T ATE344270T1 AT E344270 T1 ATE344270 T1 AT E344270T1 AT 04732143 T AT04732143 T AT 04732143T AT 04732143 T AT04732143 T AT 04732143T AT E344270 T1 ATE344270 T1 AT E344270T1
Authority
AT
Austria
Prior art keywords
decladinosyl
homoerythromycin
deoxo
aza
carbamoyl
Prior art date
Application number
AT04732143T
Other languages
English (en)
Inventor
Istuk Zorica Marusic
Nedjeljko Kujundzic
Stjepan Mutak
Original Assignee
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Zagreb filed Critical Glaxosmithkline Zagreb
Application granted granted Critical
Publication of ATE344270T1 publication Critical patent/ATE344270T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cosmetics (AREA)
  • Thermal Transfer Or Thermal Recording In General (AREA)
AT04732143T 2003-05-14 2004-05-11 Neue 3-decladinosyl-9a-n-carbamoyl- und 9a-n- thiocarbamoylderivate von 9-deoxo-9-dihydro-9a- aza-9a-homoerythromycin a ATE344270T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR20030381A HRP20030381B1 (en) 2003-05-14 2003-05-14 3-DECLADINOZYL 9a-N-CARBAMOYL AND 9a-N-THIOCARBAMOYL DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICYNE A

Publications (1)

Publication Number Publication Date
ATE344270T1 true ATE344270T1 (de) 2006-11-15

Family

ID=33446264

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04732143T ATE344270T1 (de) 2003-05-14 2004-05-11 Neue 3-decladinosyl-9a-n-carbamoyl- und 9a-n- thiocarbamoylderivate von 9-deoxo-9-dihydro-9a- aza-9a-homoerythromycin a

Country Status (19)

Country Link
US (1) US20070066544A1 (de)
EP (1) EP1631575B1 (de)
JP (1) JP2007501268A (de)
CN (1) CN100345860C (de)
AR (1) AR044320A1 (de)
AT (1) ATE344270T1 (de)
CA (1) CA2525143A1 (de)
CL (1) CL2004001026A1 (de)
CY (1) CY1107321T1 (de)
DE (1) DE602004003054T2 (de)
DK (1) DK1631575T3 (de)
ES (1) ES2274453T3 (de)
HR (1) HRP20030381B1 (de)
IS (1) IS8109A (de)
PL (1) PL1631575T3 (de)
PT (1) PT1631575E (de)
RS (1) RS20050837A (de)
SI (1) SI1631575T1 (de)
WO (1) WO2004101591A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080200403A1 (en) * 2005-01-14 2008-08-21 Glaxosmithkline 9A-Carbamoyl and Thiocarbamoyl Azalides with Anti-Inflammatory Activity
EP1841437B1 (de) * 2005-01-14 2009-04-29 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. 9a-carbamoyl- und thiocarbamoylazalide mit antimalariawirkung
BR112015025159A2 (pt) 2013-04-04 2017-07-18 Harvard College macrolídeos e métodos de sua preparação e uso
CN104119413B (zh) * 2014-07-29 2016-08-24 华中农业大学 一种土拉霉素残留标示物的合成方法
HK1242920A1 (zh) 2014-10-08 2018-07-06 哈佛大学的校长及成员们 14-元酮内酯及其制备和使用方法
WO2016154591A1 (en) 2015-03-25 2016-09-29 President And Fellows Of Harvard College Macrolides with modified desosamine sugars and uses thereof
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds
SG11202105227QA (en) * 2018-11-19 2021-06-29 Zikani Therapeutics Inc C10-alkylene substituted 13-membered macrolides and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI7910768A8 (en) * 1979-04-02 1996-06-30 Pliva Pharm & Chem Works Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives
HRP931480B1 (en) * 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A
HRP990130B1 (en) * 1999-05-03 2004-06-30 Pliva D D HALOGEN DERIVATIVES 9a-N-(N'-ARYLCARBAMOYL)- AND 9a-N-(N'-ARYLTHIOCARBAMOYL)-9-DEOXO-9a-AZA-9a OF HOMOERYTHROMYCIN A
US20020115621A1 (en) * 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
HRP20010146B1 (en) * 2001-02-28 2005-10-31 Pliva D.D. 9a-N-(N'-(PHENYLSULFONYL)CARBAMOYL) DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMYCIN A AND OF 5-O-DESOSAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHRONOLIDE A
US6933283B2 (en) * 2002-04-25 2005-08-23 Abbott Laboratories 11-deoxy azalide antibacterials

Also Published As

Publication number Publication date
CN1788013A (zh) 2006-06-14
HRP20030381A2 (en) 2005-02-28
WO2004101591A1 (en) 2004-11-25
ES2274453T3 (es) 2007-05-16
DE602004003054D1 (de) 2006-12-14
SI1631575T1 (sl) 2007-04-30
JP2007501268A (ja) 2007-01-25
PT1631575E (pt) 2007-01-31
DE602004003054T2 (de) 2007-06-06
IS8109A (is) 2005-10-31
PL1631575T3 (pl) 2007-03-30
HK1092156A1 (en) 2007-02-02
CN100345860C (zh) 2007-10-31
US20070066544A1 (en) 2007-03-22
CA2525143A1 (en) 2004-11-25
AR044320A1 (es) 2005-09-07
EP1631575B1 (de) 2006-11-02
CL2004001026A1 (es) 2005-04-22
CY1107321T1 (el) 2012-11-21
EP1631575A1 (de) 2006-03-08
DK1631575T3 (da) 2007-02-26
HRP20030381B1 (en) 2007-05-31
RS20050837A (sr) 2007-12-31

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