ATE345344T1 - (oxopyrazolo 1,5aöpyrimidin-2-yl) alkylcarbonsäureamide - Google Patents
(oxopyrazolo 1,5aöpyrimidin-2-yl) alkylcarbonsäureamideInfo
- Publication number
- ATE345344T1 ATE345344T1 AT02728576T AT02728576T ATE345344T1 AT E345344 T1 ATE345344 T1 AT E345344T1 AT 02728576 T AT02728576 T AT 02728576T AT 02728576 T AT02728576 T AT 02728576T AT E345344 T1 ATE345344 T1 AT E345344T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- oxopyrazolo
- carbonic acid
- acid amides
- alkyl carbonic
- Prior art date
Links
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 2
- 210000003169 central nervous system Anatomy 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229960003692 gamma aminobutyric acid Drugs 0.000 abstract 2
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 abstract 2
- SVUOLADPCWQTTE-UHFFFAOYSA-N 1h-1,2-benzodiazepine Chemical compound N1N=CC=CC2=CC=CC=C12 SVUOLADPCWQTTE-UHFFFAOYSA-N 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 244000144972 livestock Species 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27914701P | 2001-03-27 | 2001-03-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE345344T1 true ATE345344T1 (de) | 2006-12-15 |
Family
ID=23067823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02728576T ATE345344T1 (de) | 2001-03-27 | 2002-03-27 | (oxopyrazolo 1,5aöpyrimidin-2-yl) alkylcarbonsäureamide |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6703393B2 (de) |
| EP (1) | EP1392692B1 (de) |
| JP (1) | JP2004525937A (de) |
| AT (1) | ATE345344T1 (de) |
| BR (1) | BR0208241A (de) |
| CA (1) | CA2441926A1 (de) |
| DE (1) | DE60216083T2 (de) |
| ES (1) | ES2276936T3 (de) |
| MX (1) | MXPA03008681A (de) |
| WO (1) | WO2002076987A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0303910D0 (en) * | 2003-02-20 | 2003-03-26 | Merck Sharp & Dohme | Therapeutic agents |
| WO2005108401A1 (en) * | 2004-04-29 | 2005-11-17 | Dov Pharmaceutical, Inc. | 2-pyridinyl[7-(substituted-pyridin-4-yl) pyrazolo[1,5-a]pyrimidin-3-yl]methanones |
| ES2399071T3 (es) | 2006-10-16 | 2013-03-25 | Bionomics Limited | Nuevos compuestos ansiolíticos |
| US10954231B2 (en) | 2006-10-16 | 2021-03-23 | Bionomics Limited | Anxiolytic compounds |
| JP2014510065A (ja) | 2011-03-02 | 2014-04-24 | バイオノミックス リミテッド | 治療薬としての新規な小分子 |
| JP6055817B2 (ja) | 2011-05-12 | 2016-12-27 | バイオノミックス リミテッド | ナフチリジンの調製方法 |
| US9403835B2 (en) | 2011-12-22 | 2016-08-02 | Ares Trading S.A. | Tetraaza-cyclopenta[a]indenyl and their use as positive allosteric modulators |
| EP2674434A1 (de) * | 2012-06-11 | 2013-12-18 | Ares Trading S.A. | Tetraaza-Cyclopenta[a]indenyl und seine Verwendung als positive allosterische Modulatoren |
| US20150374705A1 (en) | 2012-02-14 | 2015-12-31 | Shanghai Institues for Biological Sciences | Substances for treatment or relief of pain |
| JP2018076234A (ja) * | 2015-03-16 | 2018-05-17 | 大正製薬株式会社 | ピラゾロ［１，５−ａ］ピリミジン化合物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2157285B (en) | 1984-04-11 | 1987-10-28 | Erba Farmitalia | 1h, 7h-pyrazolo1, 5-a pyrimidine-7-one derivatives and process for their preparation |
| US4950585A (en) * | 1987-08-18 | 1990-08-21 | Konica Corporation | Coupler for photographic use |
| WO1992018504A1 (en) * | 1991-04-22 | 1992-10-29 | Otsuka Pharmaceutical Factory, Inc. | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVE AND ANTI-INFLAMMATORY CONTAINING THE SAME |
| AU707530B2 (en) | 1995-09-28 | 1999-07-15 | Otsuka Pharmaceutical Factory, Inc. | Analgesic composition |
| US5723608A (en) | 1996-12-31 | 1998-03-03 | Neurogen Corporation | 3-aryl substituted pyrazolo 4,3-d!pyrimidine derivatives; corticotropin-releasing factor receptor (CRF1) specific ligands |
| US6358949B1 (en) | 1999-04-02 | 2002-03-19 | Neurogen Corporation | Aryl and hetroaryl fused aminoalkyl-imidazole derivatives: selective modulators of bradykinin B2 receptors |
| US6380210B1 (en) | 1999-04-02 | 2002-04-30 | Neurogen Corporation | Heteroaryl fused aminoalkyl-imidazole derivatives: selective modulators of GABAa receptors |
| US6271241B1 (en) | 1999-04-02 | 2001-08-07 | Neurogen Corporation | Cycloalkyl and aryl fused aminoalkyl-imidazole derivatives: modulators and GLP-1 receptors |
| WO2001053298A1 (en) | 2000-01-18 | 2001-07-26 | Neurogen Corporation | Imidazopyridines and related azacyclic derivatives as selective modulators of bradykinin b2 receptors |
| US6723332B2 (en) | 2000-05-26 | 2004-04-20 | Neurogen Corporation | Oxomidazopyridine-carboxamides |
| AU2001270297A1 (en) | 2000-06-30 | 2002-01-14 | Neurogen Corporation | 2-phenylimidazo(1,2-a)pyridine derivatives: a new class of gaba brain receptor ligands |
| MXPA03001951A (es) | 2000-09-06 | 2003-10-15 | Neurogen Corp | Pirroliminas y pirazoliminas fusionadas substituidas. |
| BR0113697A (pt) | 2000-09-06 | 2003-07-22 | Neurogen Corp | Composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto ou sal, embalagem e métodos para, para alterar a atividade transdutora de sinal dos receptores de gabaa, para tratar ansiedade, depressão, um distúrbio do sono, ou demência de alzheimer, para demonstrar a presença dos receptores de gabaa em células ou amostras de tecido e para preparar um composto |
| US6833371B2 (en) * | 2001-11-01 | 2004-12-21 | Icagen, Inc. | Pyrazolopyrimidines |
-
2002
- 2002-03-27 WO PCT/US2002/009339 patent/WO2002076987A1/en not_active Ceased
- 2002-03-27 MX MXPA03008681A patent/MXPA03008681A/es active IP Right Grant
- 2002-03-27 EP EP02728576A patent/EP1392692B1/de not_active Expired - Lifetime
- 2002-03-27 JP JP2002576245A patent/JP2004525937A/ja active Pending
- 2002-03-27 AT AT02728576T patent/ATE345344T1/de not_active IP Right Cessation
- 2002-03-27 US US10/107,790 patent/US6703393B2/en not_active Expired - Fee Related
- 2002-03-27 BR BR0208241-1A patent/BR0208241A/pt not_active IP Right Cessation
- 2002-03-27 CA CA002441926A patent/CA2441926A1/en not_active Abandoned
- 2002-03-27 DE DE60216083T patent/DE60216083T2/de not_active Expired - Fee Related
- 2002-03-27 ES ES02728576T patent/ES2276936T3/es not_active Expired - Lifetime
-
2004
- 2004-03-09 US US10/796,509 patent/US7008947B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6703393B2 (en) | 2004-03-09 |
| DE60216083T2 (de) | 2007-06-28 |
| BR0208241A (pt) | 2004-04-13 |
| MXPA03008681A (es) | 2004-04-02 |
| JP2004525937A (ja) | 2004-08-26 |
| DE60216083D1 (de) | 2006-12-28 |
| WO2002076987A1 (en) | 2002-10-03 |
| US20030109536A1 (en) | 2003-06-12 |
| EP1392692B1 (de) | 2006-11-15 |
| US7008947B2 (en) | 2006-03-07 |
| CA2441926A1 (en) | 2002-10-03 |
| US20040176397A1 (en) | 2004-09-09 |
| EP1392692A1 (de) | 2004-03-03 |
| ES2276936T3 (es) | 2007-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |