ATE346954T1 - Nachweis von mycobacterium tuberculosis durch vervielfältigung von nukleinsäuresequenzen - Google Patents
Nachweis von mycobacterium tuberculosis durch vervielfältigung von nukleinsäuresequenzenInfo
- Publication number
- ATE346954T1 ATE346954T1 AT99121906T AT99121906T ATE346954T1 AT E346954 T1 ATE346954 T1 AT E346954T1 AT 99121906 T AT99121906 T AT 99121906T AT 99121906 T AT99121906 T AT 99121906T AT E346954 T1 ATE346954 T1 AT E346954T1
- Authority
- AT
- Austria
- Prior art keywords
- duplication
- detection
- nucleic acid
- acid sequences
- mycobacterium tuberculosis
- Prior art date
Links
- 241000187479 Mycobacterium tuberculosis Species 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 150000007523 nucleic acids Chemical group 0.000 title 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 201000008827 tuberculosis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- AIDS & HIV (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92540592A | 1992-08-04 | 1992-08-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE346954T1 true ATE346954T1 (de) | 2006-12-15 |
Family
ID=25451694
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99121906T ATE346954T1 (de) | 1992-08-04 | 1993-08-04 | Nachweis von mycobacterium tuberculosis durch vervielfältigung von nukleinsäuresequenzen |
| AT93306169T ATE197479T1 (de) | 1992-08-04 | 1993-08-04 | Verfahren zur vervielfältigung von nukleinsäuresequenzen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93306169T ATE197479T1 (de) | 1992-08-04 | 1993-08-04 | Verfahren zur vervielfältigung von nukleinsäuresequenzen |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP0587298B1 (de) |
| JP (3) | JP4372837B2 (de) |
| KR (1) | KR100316498B1 (de) |
| AT (2) | ATE346954T1 (de) |
| AU (2) | AU670116B2 (de) |
| CA (1) | CA2141430C (de) |
| DE (2) | DE69329636T2 (de) |
| ES (1) | ES2277679T3 (de) |
| NO (1) | NO950381L (de) |
| TW (1) | TW278099B (de) |
| WO (1) | WO1994003472A1 (de) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5981179A (en) * | 1991-11-14 | 1999-11-09 | Digene Diagnostics, Inc. | Continuous amplification reaction |
| WO1995015399A1 (en) * | 1993-12-01 | 1995-06-08 | Toyo Boseki Kabushiki Kaisha | Method of amplifying and detecting target nucleic acid sequence by using thermostable enzymes |
| FR2724934B1 (fr) * | 1994-09-26 | 1997-01-24 | Bio Merieux | Oligonucleotide chimere et son utilisation dans l'obtention de transcrits d'un acide nucleique |
| US5514551A (en) * | 1994-10-14 | 1996-05-07 | Gen-Probe Incorporated | Compositions for the detection of Chlamydia trachomatis |
| CA2209991C (en) * | 1995-01-19 | 2005-04-12 | Gen-Probe Incorporated | Nucleic acid amplification oligonucleotides and probes to lyme disease associated borrelia |
| US5622827A (en) * | 1995-02-07 | 1997-04-22 | Gen-Probe Incorporated | Amplification primers and nucleic acid probes targeted to coccidioides immitis nucleic acid |
| EP0826066B1 (de) | 1995-05-05 | 2000-09-13 | The Perkin-Elmer Corporation | Methoden and reagentien fuer die kombination einer pcr-amplifizierung mit einem hybridisierungs-assay |
| US5925518A (en) * | 1995-05-19 | 1999-07-20 | Akzo Nobel N.V. | Nucleic acid primers for amplification of a mycobacteria RNA template |
| US5710029A (en) * | 1995-06-07 | 1998-01-20 | Gen-Probe Incorporated | Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product |
| CA2223241C (en) * | 1995-06-07 | 2009-11-17 | Gen-Probe Incorporated | Methods and kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product |
| US5882857A (en) * | 1995-06-07 | 1999-03-16 | Behringwerke Ag | Internal positive controls for nucleic acid amplification |
| US5916777A (en) * | 1995-06-07 | 1999-06-29 | Gen-Probe Incorporated | Enzymatic synthesis of oligonucleotides using 3'-ribonucleotide primers |
| US5705365A (en) * | 1995-06-07 | 1998-01-06 | Gen-Probe Incorporated | Kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product |
| US5932450A (en) * | 1995-06-07 | 1999-08-03 | Gen-Probe Incorporated | Enzymatic synthesis of oligonucleotides using digestible templates |
| US5652126A (en) * | 1995-06-07 | 1997-07-29 | Gen-Probe Incorporated | Use of restriction endonuclease sequences for cleaving phosphorothioate oligonucleotides |
| US5739311A (en) * | 1995-06-07 | 1998-04-14 | Gen-Probe Incorporated | Enzymatic synthesis of phosphorothioate oligonucleotides using restriction endonucleases |
| CA2222305A1 (en) * | 1995-06-07 | 1996-12-19 | Gen-Probe Incorporated | Nucleic acid probes and amplification oligonucleotides for neisseria species |
| US5747252A (en) | 1995-06-07 | 1998-05-05 | Gen-Probe Incorporated | Nucleic acid probes and amplification oligonucleotides for Neisseria species |
| CA2246238A1 (en) * | 1996-03-01 | 1997-09-04 | E.I. Du Pont De Nemours And Company | A method for the amplification and detection of a nucleic acid fragment of interest |
| AU710996B2 (en) | 1996-05-22 | 1999-10-07 | Gen-Probe Incorporated | Compositions and methods for the detection of mycobacterium kansasii |
| US6013488A (en) * | 1996-07-25 | 2000-01-11 | The Institute Of Physical And Chemical Research | Method for reverse transcription |
| US6057134A (en) * | 1996-10-07 | 2000-05-02 | Ambion, Inc. | Modulating the efficiency of nucleic acid amplification reactions with 3' modified oligonucleotides |
| AU746549B2 (en) | 1996-11-20 | 2002-05-02 | Becton Dickinson & Company | Microfabricated isothermal nucleic acid amplification devices and methods |
| GB9626074D0 (en) * | 1996-12-16 | 1997-02-05 | Cytocell Ltd | Nucleic acids amplification assay |
| US6025133A (en) * | 1996-12-30 | 2000-02-15 | Gen-Probe Incorporated | Promoter-sequestered oligonucleoside and method of use |
| US6534273B2 (en) | 1997-05-02 | 2003-03-18 | Gen-Probe Incorporated | Two-step hybridization and capture of a polynucleotide |
| ES2271994T3 (es) | 1997-05-02 | 2007-04-16 | Gen-Probe Incorporated | Hibridacion en dos pasos y captura de un polinucleotido. |
| DE69833864T2 (de) * | 1997-08-14 | 2006-12-21 | Takara Bio Inc., Otsu | Methoden zur dns vervielfältigung und material dafür |
| JP2002509443A (ja) * | 1997-10-31 | 2002-03-26 | ジェン−プローブ・インコーポレーテッド | 核酸検出法 |
| US5932451A (en) * | 1997-11-19 | 1999-08-03 | Incyte Pharmaceuticals, Inc. | Method for unbiased mRNA amplification |
| JP4438110B2 (ja) * | 1998-07-01 | 2010-03-24 | 東ソー株式会社 | 標的核酸の定量方法 |
| WO2000070039A1 (en) * | 1999-05-17 | 2000-11-23 | Mcgill University | METHOD FOR SUBTRACTING cDNAs BY SUPPRESSING THE SYNTHESIS OF SPECIFICALLY TARGETED mRNAs |
| DK1238100T3 (da) | 1999-07-23 | 2006-01-23 | Gen Probe Inc | Polynucleotid-amplifikationsfremgangsmåde |
| US6489114B2 (en) | 1999-12-17 | 2002-12-03 | Bio Merieux | Process for labeling a ribonucleic acid, and labeled RNA fragments which are obtained thereby |
| US6902891B2 (en) | 1999-12-17 | 2005-06-07 | Bio Merieux | Process for labeling a nucleic acid |
| JP2002051778A (ja) * | 2000-05-31 | 2002-02-19 | Tosoh Corp | 小型球形ウイルス（ｓｒｓｖ）ｒｎａ検出のためのオリゴヌクレオチドおよび検出法 |
| AU2001291513B2 (en) * | 2000-10-03 | 2007-06-07 | Id+Plus Ltd | Nucleotide detection method |
| AUPR050700A0 (en) | 2000-10-03 | 2000-10-26 | Id+Plus Ltd | Detection method |
| ATE386821T1 (de) | 2000-10-23 | 2008-03-15 | Gen Probe Inc | Zusammensetzungen und methoden zur detektion von humanem immundefizienz virus 2 (hiv-2) |
| JP2002125688A (ja) * | 2000-10-30 | 2002-05-08 | Tosoh Corp | Ｃ型肝炎ウイルスの高感度検出のためのオリゴヌクレオチドおよび検出法 |
| DE10119203B4 (de) * | 2001-04-19 | 2004-09-16 | Rolf Dr. Postina | Verfahren zur Erzeugung von doppelsträngigen Nukleinsäuren mit einzelsträngigen Überhängen beliebiger Länge und Nukleotidzusammensetzung |
| AU2003253651C1 (en) | 2002-06-14 | 2010-06-03 | Gen-Probe Incorporated | Compositions and methods for detecting hepatitis B virus |
| CA2957200C (en) | 2002-10-16 | 2020-05-26 | Gen-Probe Incorporated | Compositions and methods for detecting west nile virus |
| CA2547750C (en) | 2003-12-19 | 2014-04-08 | Gen-Probe Incorporated | Compositions, methods and kits for detecting the nucleic acids of hiv-1 and hiv-2 |
| ES2759991T3 (es) | 2004-09-30 | 2020-05-12 | Gen Probe Inc | Ensayo para detectar y cuantificar el VIH-1 |
| CA2582661C (en) | 2004-11-09 | 2015-08-11 | Gen-Probe Incorporated | Compositions and methods for detecting group a streptococci |
| CA2597319C (en) | 2005-02-18 | 2014-09-30 | Gen-Probe Incorporated | Sample preparation method incorporating an alkaline shock |
| EP2471805A3 (de) | 2005-05-06 | 2013-01-16 | Gen-Probe Incorporated | Zusammensetzungen und Verfahren zur spezifischen Detektion von Nukleinsäuren der Viren Influenza A oder B |
| JP5071987B2 (ja) | 2005-11-14 | 2012-11-14 | ジェン−プロウブ インコーポレイテッド | パラメトリック較正方法 |
| JP5481189B2 (ja) * | 2006-05-24 | 2014-04-23 | ジェン−プロウブ インコーポレイテッド | 試験サンプルにおけるＭｙｃｏｂａｃｔｅｒｉｕｍｔｕｂｅｒｃｕｌｏｓｉｓ複合体生物の存在を決定するためのプローブおよびキット、ならびに捕捉プローブを使用するグラム陽性桿菌または真菌の増幅方法 |
| EP1921156A1 (de) * | 2006-11-10 | 2008-05-14 | bioMerieux B.V. | Verbesserte multiplexe Nukleinsäureamplifikation mittels blockierter Primer |
| GB0701253D0 (en) | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
| EP1978111B1 (de) * | 2007-04-02 | 2013-03-27 | Gen-Probe Incorporated | Zusammensetzungen, Kits und zugehörige Verfahren zur Erkennung und/oder Überwachung von Pseudomonas aeruginosa |
| EP3957754B1 (de) | 2008-04-21 | 2026-01-28 | Gen-Probe Incorporated | Verfahren zur erkennung des chikungunya-virus |
| EP3118208A1 (de) | 2009-02-26 | 2017-01-18 | Gen-Probe Incorporated | Assay zum nachweisen menschlicher parvovirennukleinsäure |
| EP3305920B1 (de) | 2010-07-12 | 2020-02-12 | Gen-Probe Incorporated | Zusammensetzungen und assays zur erkennung von saisonaler h3-influenza a-virus-nukleinsäure |
| WO2012030856A2 (en) | 2010-08-30 | 2012-03-08 | Gen-Probe Incorporated | Compositions, methods and reaction mixtures for the detection of xenotropic murine leukemia virus-related virus |
| WO2013012708A1 (en) | 2011-07-15 | 2013-01-24 | Gen-Probe Incorporated | Compositions and method for detecting human parvovirus nucleic acid and for detecting hepatitis a virus nucleic acids in single-plex or multiplex assays |
| US9932628B2 (en) | 2012-07-27 | 2018-04-03 | Gen-Probe Incorporated | Dual reference calibration method and system for quantifying polynucleotides |
| CA2899645C (en) | 2013-03-15 | 2022-08-30 | Gen-Probe Incorporated | Calibration method, apparatus and computer program product |
| EP4219771A3 (de) | 2017-03-24 | 2023-08-16 | Gen-Probe Incorporated | Zusammensetzungen und verfahren für den multiplexnachweis viraler krankheitserreger in proben |
| EP4282985A3 (de) | 2017-03-24 | 2024-02-28 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zum nachweis oder zur quantifizierung des parainfluenzavirus |
| CA3072452A1 (en) | 2017-08-11 | 2019-02-14 | Gen-Probe Incorporated | Compositions and methods for detecting staphylococcus aureus |
| EP3724354A1 (de) | 2017-12-15 | 2020-10-21 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zum nachweis von toxigenem clostridium difficile |
| CA3103442A1 (en) | 2018-06-13 | 2019-12-19 | Gen-Probe Incorporated | Compositions and methods for detecting group b streptococcus nucleic acid |
| US12227812B2 (en) | 2018-08-01 | 2025-02-18 | Gen-Probe Incorporated | Compositions and methods for detecting nucleic acids of Epstein-Barr virus |
| AU2019319203B8 (en) | 2018-08-08 | 2025-10-09 | Gen-Probe Incorporated | Compositions, methods and kits for detecting Mycoplasma genitalium |
| CA3107043A1 (en) | 2018-08-21 | 2020-02-27 | Gen-Probe Incorporated | Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus |
| CA3112651A1 (en) | 2018-09-27 | 2020-04-02 | Gen-Probe Incorporated | Compositions and methods for detecting bordetella pertussis and bordetella parapertussis nucleic acid |
| AU2019365821C1 (en) | 2018-10-22 | 2025-08-14 | Gen-Probe Incorporated | Compositions and methods for amplifying, detecting or quantifying human polyomavirus BK virus |
| AU2020335996A1 (en) | 2019-08-23 | 2022-03-31 | Gen-Probe Incorporated | Compositions, methods and kits for detecting Treponema pallidum |
| WO2021046270A1 (en) | 2019-09-05 | 2021-03-11 | Gen-Probe Incorporated | Detection of chlamydia trachomatis nucleic acid variants |
| EP4361284B1 (de) | 2019-12-09 | 2025-09-10 | Gen-Probe Incorporated | Quantifizierung von polynukleotidanalyten aus getrockneten proben |
| AU2021230341C8 (en) | 2020-03-04 | 2026-05-07 | Gen-Probe Incorporated | Compositions and methods for detecting SARS-CoV-2 nucleic acid |
| CA3226812A1 (en) | 2021-07-27 | 2023-02-02 | Gen-Probe Incorporated | Compositions and methods for detecting gastrointestinal pathogens |
| KR102544380B1 (ko) | 2022-01-29 | 2023-06-16 | (주)동방지퍼 | 지퍼용 슬라이더와 손잡이의 결착방법 및 이로 인해 제조된 지퍼 |
| EP4282980A1 (de) | 2022-05-23 | 2023-11-29 | Mobidiag Oy | Methoden zum verstärken einer nukleinsäure |
| WO2024054924A1 (en) | 2022-09-08 | 2024-03-14 | Gen-Probe Incorporated | Method of detecting nucleic acid analytes using dual-specificity primers |
| AU2024267362A1 (en) | 2023-05-05 | 2025-11-13 | Gen-Probe Incorporated | Method and system for improving specificity of analyte detection using real-time nucleic acid amplification |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988003957A1 (en) * | 1986-11-24 | 1988-06-02 | Gen-Probe Incorporated | Nucleic acid probes for detection and/or quantitation of non-viral organisms |
| IL86724A (en) * | 1987-06-19 | 1995-01-24 | Siska Diagnostics Inc | Methods and kits for amplification and testing of nucleic acid sequences |
| US4994368A (en) * | 1987-07-23 | 1991-02-19 | Syntex (U.S.A.) Inc. | Amplification method for polynucleotide assays |
| US5480784A (en) * | 1989-07-11 | 1996-01-02 | Gen-Probe Incorporated | Nucleic acid sequence amplification methods |
| DE69118930T2 (de) * | 1990-01-26 | 1997-01-09 | Abbott Lab | Verbessertes Verfahren zur Amplifikation von Nuklein säurezielsequenz, einsetzbar für die Polymerase und Ligasekettenreaktion |
| WO1992007957A1 (en) * | 1990-10-31 | 1992-05-14 | Cimino George D | Methods and compositions for minimizing inhibition of nucleic acid amplification |
| US5169766A (en) * | 1991-06-14 | 1992-12-08 | Life Technologies, Inc. | Amplification of nucleic acid molecules |
| US5521300A (en) * | 1991-08-13 | 1996-05-28 | Norval B. Galloway | Oligonucleotides complementary to mycobacterial nucleic acids |
| CA2135073C (en) * | 1992-05-06 | 2002-11-19 | Daniel L. Kacian | Nucleic acid sequence amplification method, composition and kit |
-
1993
- 1993-07-28 JP JP50543394A patent/JP4372837B2/ja not_active Expired - Fee Related
- 1993-07-28 AU AU47920/93A patent/AU670116B2/en not_active Ceased
- 1993-07-28 WO PCT/US1993/007138 patent/WO1994003472A1/en not_active Ceased
- 1993-07-28 CA CA002141430A patent/CA2141430C/en not_active Expired - Lifetime
- 1993-07-28 KR KR1019950700406A patent/KR100316498B1/ko not_active Expired - Lifetime
- 1993-07-31 TW TW082106132A patent/TW278099B/zh active
- 1993-08-04 ES ES99121906T patent/ES2277679T3/es not_active Expired - Lifetime
- 1993-08-04 AT AT99121906T patent/ATE346954T1/de not_active IP Right Cessation
- 1993-08-04 DE DE69329636T patent/DE69329636T2/de not_active Expired - Lifetime
- 1993-08-04 AT AT93306169T patent/ATE197479T1/de active
- 1993-08-04 EP EP93306169A patent/EP0587298B1/de not_active Expired - Lifetime
- 1993-08-04 EP EP99121906A patent/EP0978570B1/de not_active Expired - Lifetime
- 1993-08-04 DE DE69334092T patent/DE69334092T2/de not_active Expired - Lifetime
-
1995
- 1995-02-02 NO NO950381A patent/NO950381L/no unknown
-
1996
- 1996-10-04 AU AU68027/96A patent/AU700253B2/en not_active Ceased
-
2003
- 2003-12-26 JP JP2003433721A patent/JP3860809B2/ja not_active Expired - Lifetime
-
2006
- 2006-05-10 JP JP2006131455A patent/JP2006238892A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006238892A (ja) | 2006-09-14 |
| EP0978570B1 (de) | 2006-11-29 |
| JP2004194662A (ja) | 2004-07-15 |
| NO950381D0 (no) | 1995-02-02 |
| JPH07509368A (ja) | 1995-10-19 |
| EP0978570A3 (de) | 2000-04-12 |
| ATE197479T1 (de) | 2000-11-11 |
| ES2277679T3 (es) | 2007-07-16 |
| EP0587298A3 (en) | 1995-08-30 |
| JP4372837B2 (ja) | 2009-11-25 |
| NO950381L (no) | 1995-04-03 |
| CA2141430A1 (en) | 1994-02-17 |
| AU670116B2 (en) | 1996-07-04 |
| WO1994003472A1 (en) | 1994-02-17 |
| EP0587298A2 (de) | 1994-03-16 |
| JP3860809B2 (ja) | 2006-12-20 |
| EP0978570A2 (de) | 2000-02-09 |
| EP0587298B1 (de) | 2000-11-08 |
| AU6802796A (en) | 1996-12-19 |
| DE69334092T2 (de) | 2007-07-05 |
| DE69334092D1 (de) | 2007-01-11 |
| CA2141430C (en) | 2009-05-12 |
| KR950702999A (ko) | 1995-08-23 |
| KR100316498B1 (ko) | 2002-06-20 |
| DE69329636D1 (de) | 2000-12-14 |
| AU4792093A (en) | 1994-03-03 |
| TW278099B (de) | 1996-06-11 |
| DE69329636T2 (de) | 2001-03-01 |
| AU700253B2 (en) | 1998-12-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69334092D1 (de) | Nachweis von Mycobacterium tuberculosis durch Vervielfältigung von Nukleinsäuresequenzen | |
| ATE127854T1 (de) | Verfahren für affinitätsuntersuchungen durch verwendung von ziel-amplifizierung. | |
| DE69524083D1 (de) | Stoffen und verfahren zum nachweis von mycobakterium tuberculosis | |
| DE69637726D1 (de) | Gruppen zum einfangen von nukleinsäuren | |
| EP1961826A3 (de) | Verfahren zur direkten Sequenzierung von Nukleinsäuren | |
| DE69607830D1 (de) | Verfahren zur isothermer amplifikation von nukleinsäure molekülen | |
| DE69534933D1 (de) | Nachweis von Pilzpathogenen durch Anwendung der polymerase Kettenreaktion | |
| DE69426956D1 (de) | Nachweis von Mycobakterien durch Nukleinsäure-Multiplexamplifizierung | |
| CA2230967A1 (en) | Improved nucleic acid assays | |
| DK0702728T3 (da) | Magnetisk cyklusreaktion | |
| DE69307503D1 (de) | Chemisches verfahren zur analyse von dns-sequenzen | |
| ATE247174T1 (de) | Verfahren zum besonders sensitiven nachweis von nukleinsäuren | |
| ATE211769T1 (de) | Oligonukleotide und verfahren zum nachweis von chlamydia trachomatis | |
| FI950487L (fi) | Menetelmä, reagenssi ja testipakkaus nukleiinihapposekvenssien totamiseksi ja monistamiseksi | |
| ATE206764T1 (de) | Verfahren zum sensitiven nachweis von nukleinsäuren | |
| ATE353973T1 (de) | Die verwendung der 3'-wesentlichen bearbeitungswirksamkeit von dns-polymerase | |
| DE69427103D1 (de) | Verfahren, Reagenzien und Kits zur Untersuchung von Neisseria gonorrhoeae und Chlamydia trachomatis | |
| DE69407187D1 (de) | Identifizierung von salmonella durch die polymerase-ketten-reaktion | |
| ATE534749T1 (de) | Sonde und primer zum nachweis von tuberkelbazillen sowie verfahren zum nachweis von tuberkelbazillen beim menschen damit | |
| MY118636A (en) | Probes to mycobacterium avium, mycobacterium intracellulare and mycobacterium paratuberculosis | |
| DE59608651D1 (de) | Verfahren zur sequenzierung durch oligomerhybridisierung | |
| DK0572120T3 (da) | Nucleinsyre-probertil mycobacterium tuberculosis | |
| ATE495268T1 (de) | Nukleinsäureamplifizierung und detektion von mykobacterium-spezies | |
| WO1995031571A3 (en) | Materials and methods for the detection of mycobacteria | |
| ATE312204T1 (de) | Methoden und zusammensetzungen zur detektion von spezies des mycobacterium avium-komplexes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0978570 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |