NO950381L - Nukleinsyresekvens amplifikasjon - Google Patents

Nukleinsyresekvens amplifikasjon

Info

Publication number
NO950381L
NO950381L NO950381A NO950381A NO950381L NO 950381 L NO950381 L NO 950381L NO 950381 A NO950381 A NO 950381A NO 950381 A NO950381 A NO 950381A NO 950381 L NO950381 L NO 950381L
Authority
NO
Norway
Prior art keywords
nucleic acid
acid sequence
sequence amplification
amplification
oligonucleotides
Prior art date
Application number
NO950381A
Other languages
English (en)
Other versions
NO950381D0 (no
Inventor
Sherol H Macdonough
Daniel Louis Kacian
Nanibhushan Dattagupta
Diane L Mcallister
Philip H Hammond
Thomas B Ryder
Original Assignee
Gen Probe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Publication of NO950381D0 publication Critical patent/NO950381D0/no
Publication of NO950381L publication Critical patent/NO950381L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Fremgangsmåte, blanding og kit for å syntetisere multiple kopier av en targetnukleinsyresekvens autolytisk under betingelser med vesentlig konstant temperatur, ionestyrke og pH er tilveiebrakt, hvor multiple RNA kopier av targetsekvensen autolytisk danner ytterligere kopier ved anvendelse av en blanding av blokkerte og ikke-blokkerte primere og/eller promoter-primere til å initiere DNA og RNA syntese, foretrukket med redusert dannelse av ikke-spesifikt produkt. Et av midlene for blokkering eller modifikasjon er alkan-diol som er vist i figuren. Oppfinnelsen kan anvendes for å danne kopier av en nukleinsyretargetsekvens for formål som inkluderer analyser for å kvantifisere spesifikke nuklein-syresekvenser i kliniske prøver, miljøprøver, i forbindelse med rettsmedisin og i liknende prøver, kloning og dannelse av prober.
NO950381A 1992-08-04 1995-02-02 Nukleinsyresekvens amplifikasjon NO950381L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92540592A 1992-08-04 1992-08-04
PCT/US1993/007138 WO1994003472A1 (en) 1992-08-04 1993-07-28 Nucleic acid sequence amplification

Publications (2)

Publication Number Publication Date
NO950381D0 NO950381D0 (no) 1995-02-02
NO950381L true NO950381L (no) 1995-04-03

Family

ID=25451694

Family Applications (1)

Application Number Title Priority Date Filing Date
NO950381A NO950381L (no) 1992-08-04 1995-02-02 Nukleinsyresekvens amplifikasjon

Country Status (11)

Country Link
EP (2) EP0587298B1 (no)
JP (3) JP4372837B2 (no)
KR (1) KR100316498B1 (no)
AT (2) ATE346954T1 (no)
AU (2) AU670116B2 (no)
CA (1) CA2141430C (no)
DE (2) DE69329636T2 (no)
ES (1) ES2277679T3 (no)
NO (1) NO950381L (no)
TW (1) TW278099B (no)
WO (1) WO1994003472A1 (no)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981179A (en) * 1991-11-14 1999-11-09 Digene Diagnostics, Inc. Continuous amplification reaction
EP1251182A3 (en) * 1993-12-01 2002-11-27 Toyo Boseki Kabushiki Kaisha Method of amplifying and detecting target nucleic acid sequence by using thermostable enzymes
FR2724934B1 (fr) * 1994-09-26 1997-01-24 Bio Merieux Oligonucleotide chimere et son utilisation dans l'obtention de transcrits d'un acide nucleique
US5514551A (en) * 1994-10-14 1996-05-07 Gen-Probe Incorporated Compositions for the detection of Chlamydia trachomatis
WO1996022392A2 (en) * 1995-01-19 1996-07-25 Gen-Probe Incorporated Nucleic acid amplification oligonucleotides and probes to lyme disease associated borrelia
US5622827A (en) * 1995-02-07 1997-04-22 Gen-Probe Incorporated Amplification primers and nucleic acid probes targeted to coccidioides immitis nucleic acid
EP0826066B1 (en) 1995-05-05 2000-09-13 The Perkin-Elmer Corporation Methods and reagents for combined pcr amplification and hybridization probing assay
US5925518A (en) * 1995-05-19 1999-07-20 Akzo Nobel N.V. Nucleic acid primers for amplification of a mycobacteria RNA template
US5710029A (en) * 1995-06-07 1998-01-20 Gen-Probe Incorporated Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US5652126A (en) * 1995-06-07 1997-07-29 Gen-Probe Incorporated Use of restriction endonuclease sequences for cleaving phosphorothioate oligonucleotides
US5739311A (en) * 1995-06-07 1998-04-14 Gen-Probe Incorporated Enzymatic synthesis of phosphorothioate oligonucleotides using restriction endonucleases
US5916777A (en) * 1995-06-07 1999-06-29 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using 3'-ribonucleotide primers
US5932450A (en) * 1995-06-07 1999-08-03 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using digestible templates
US5705365A (en) * 1995-06-07 1998-01-06 Gen-Probe Incorporated Kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
KR19990022595A (ko) * 1995-06-07 1999-03-25 다니엘 엘. 캐시앙, 헨리 엘. 노르호프 나이세리아 종에 대한 핵산 프로브 및 증폭 올리고뉴클레오티드
US5882857A (en) * 1995-06-07 1999-03-16 Behringwerke Ag Internal positive controls for nucleic acid amplification
US5747252A (en) * 1995-06-07 1998-05-05 Gen-Probe Incorporated Nucleic acid probes and amplification oligonucleotides for Neisseria species
AU709292B2 (en) * 1995-06-07 1999-08-26 Gen-Probe Incorporated Methods and kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
DE69734576T2 (de) * 1996-03-01 2006-08-03 E.I. Dupont De Nemours And Co., Wilmington Methode zur vervielfältigung und zum nachweis eines gewünschten nukleinsäurefragments
WO1997044488A2 (en) 1996-05-22 1997-11-27 Gen-Probe Incorporated Compositions and methods for the detection of mycobacterium kansasii
US6013488A (en) * 1996-07-25 2000-01-11 The Institute Of Physical And Chemical Research Method for reverse transcription
US6057134A (en) * 1996-10-07 2000-05-02 Ambion, Inc. Modulating the efficiency of nucleic acid amplification reactions with 3' modified oligonucleotides
EP0946749A1 (en) 1996-11-20 1999-10-06 The Regents Of The University Of Michigan Microfabricated isothermal nucleic acid amplification devices and methods
GB9626074D0 (en) * 1996-12-16 1997-02-05 Cytocell Ltd Nucleic acids amplification assay
US6025133A (en) * 1996-12-30 2000-02-15 Gen-Probe Incorporated Promoter-sequestered oligonucleoside and method of use
US6534273B2 (en) 1997-05-02 2003-03-18 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
DE69836012T2 (de) 1997-05-02 2007-04-05 Gen-Probe Inc., San Diego Zwei-schritt hybridisierung und einfang von einem polynukleotid
ATE320507T1 (de) * 1997-08-14 2006-04-15 Takara Bio Inc Methoden zur dns vervielfältigung und material dafür
AU1450699A (en) * 1997-10-31 1999-05-24 Gen-Probe Incorporated Methods of nucleic acid detection
US5932451A (en) * 1997-11-19 1999-08-03 Incyte Pharmaceuticals, Inc. Method for unbiased mRNA amplification
JP4438110B2 (ja) * 1998-07-01 2010-03-24 東ソー株式会社 標的核酸の定量方法
AU4739600A (en) * 1999-05-17 2000-12-05 Mcgill University Method for subtracting cdnas by suppressing the synthesis of specifically targeted mrnas
AU781570B2 (en) 1999-07-23 2005-06-02 Gen-Probe Incorporated Polynucleotide amplification method
US6489114B2 (en) 1999-12-17 2002-12-03 Bio Merieux Process for labeling a ribonucleic acid, and labeled RNA fragments which are obtained thereby
US6902891B2 (en) 1999-12-17 2005-06-07 Bio Merieux Process for labeling a nucleic acid
JP2002051778A (ja) * 2000-05-31 2002-02-19 Tosoh Corp 小型球形ウイルス（ｓｒｓｖ）ｒｎａ検出のためのオリゴヌクレオチドおよび検出法
AU2001291513B2 (en) * 2000-10-03 2007-06-07 Id+Plus Ltd Nucleotide detection method
AUPR050700A0 (en) 2000-10-03 2000-10-26 Id+Plus Ltd Detection method
ATE386821T1 (de) 2000-10-23 2008-03-15 Gen Probe Inc Zusammensetzungen und methoden zur detektion von humanem immundefizienz virus 2 (hiv-2)
JP2002125688A (ja) * 2000-10-30 2002-05-08 Tosoh Corp Ｃ型肝炎ウイルスの高感度検出のためのオリゴヌクレオチドおよび検出法
DE10119203B4 (de) * 2001-04-19 2004-09-16 Rolf Dr. Postina Verfahren zur Erzeugung von doppelsträngigen Nukleinsäuren mit einzelsträngigen Überhängen beliebiger Länge und Nukleotidzusammensetzung
EP1513958B1 (en) 2002-06-14 2011-08-10 Gen-Probe Incorporated Compositions for detecting hepatitis b virus
CA2868618C (en) 2002-10-16 2017-05-23 Gen-Probe Incorporated Compositions and methods for detecting west nile virus
US7255996B2 (en) 2003-12-19 2007-08-14 Gen-Probe Incorporated Compositions, methods and kits for detecting the nucleic acids of HIV-1 and HIV-2
ES2759991T3 (es) 2004-09-30 2020-05-12 Gen Probe Inc Ensayo para detectar y cuantificar el VIH-1
WO2006137939A2 (en) 2004-11-09 2006-12-28 Gen-Probe Incorporated Compositions and methods for detecting group a streptococci
ATE493494T1 (de) 2005-02-18 2011-01-15 Gen Probe Inc Probenherstellungsverfahren mit einem alkali- stoss
WO2006121773A2 (en) 2005-05-06 2006-11-16 Gen-Probe Incorporated Compositions and assays to detect influenza virus a and b nucleic acids
CA2627259C (en) 2005-11-14 2016-02-23 Gen-Probe Incorporated Parametric calibration method
AU2007267517B2 (en) * 2006-05-24 2012-12-20 Gen-Probe Incorporated Probes and kits for determining the presence of mycobacterium tuberculosis complex organisms in a test sample and method of amplifying gram-positive bacteria and fungi employing capture probe
EP1921156A1 (en) 2006-11-10 2008-05-14 bioMerieux B.V. Improved multiplex nucleic acid amplification using blocked primers
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
EP1978111B1 (en) * 2007-04-02 2013-03-27 Gen-Probe Incorporated Compositions, kits and related methods for the detection and/or monitoring of Pseudomonas aeruginosa
JP5646455B2 (ja) 2008-04-21 2014-12-24 ジェン−プロウブ インコーポレイテッド チクングニヤウイルスを検出するための方法
EP3118208A1 (en) 2009-02-26 2017-01-18 Gen-Probe Incorporated Assay for detection of human parvovirus nuleic acid
US9234249B2 (en) 2010-07-12 2016-01-12 Gen-Probe Incorporated Compositions and assays to detect swine H1N1 influenza A virus, seasonal H1 influenza A virus and seasonal H3 influenza A virus nucleic acids
EP2611932A2 (en) 2010-08-30 2013-07-10 Gen-Probe Incorporated Compositions, methods and reaction mixtures for the detection of xenotropic murine leukemia virus-related virus
JP6150795B2 (ja) 2011-07-15 2017-06-28 ジェン−プロウブ インコーポレイテッド シングルプレックス又はマルチプレックスアッセイにおいてヒトパルボウイルス核酸を検出及びａ型肝炎ウイルス核酸を検出するための組成物及び方法
WO2014018885A2 (en) 2012-07-27 2014-01-30 Gen-Probe Incorporated Dual reference calibration method and system for quantifying polynucleotides
US9976175B2 (en) 2013-03-15 2018-05-22 Gen-Probe Incorporated Calibration method, apparatus and computer program product
EP3601619B1 (en) 2017-03-24 2024-06-26 Gen-Probe Incorporated Compositions and methods for detection of viral pathogens in samples
CA3057154C (en) 2017-03-24 2024-11-12 Gen-Probe Incorporated COMPOSITIONS AND METHODS OF DETECTION OR QUANTIFICATION OF THE PARAINFLUENZA VIRUS
US11859257B2 (en) 2017-08-11 2024-01-02 Gen-Probe Incorporated Compositions and methods for detecting Staphylococcus aureus
EP3724354A1 (en) 2017-12-15 2020-10-21 Gen-Probe Incorporated Compositions and methods for detecting toxigenic clostridium difficile
CA3268712A1 (en) 2018-06-13 2025-10-14 Gen-Probe Incorporated Compositions and Methods for Detecting Group B Streptococcus Nucleic Acid
EP3830302B1 (en) 2018-08-01 2022-10-05 Gen-Probe Incorporated Compositions and methods for detecting nucleic acids of epstein-barr virus
US12460254B2 (en) 2018-08-08 2025-11-04 Gen-Probe Incorporated Compositions, methods and kits for detecting Mycoplasma genitalium
WO2020041414A1 (en) 2018-08-21 2020-02-27 Gen-Probe Incorporated Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus
CA3112651A1 (en) 2018-09-27 2020-04-02 Gen-Probe Incorporated Compositions and methods for detecting bordetella pertussis and bordetella parapertussis nucleic acid
WO2020086546A1 (en) 2018-10-22 2020-04-30 Gen-Probe Incorporated Compositions and methods for amplifying, detecting or quantifying human polyomavirus bk virus
US20220298548A1 (en) 2019-08-23 2022-09-22 Gen-Probe Incorporated Compositions, methods and kits for detecting treponema pallidum
JP7556945B2 (ja) 2019-09-05 2024-09-26 ジェン－プローブ・インコーポレーテッド Ｃｈｌａｍｙｄｉａ ｔｒａｃｈｏｍａｔｉｓ変異体の核酸の検出
US12037638B2 (en) 2019-12-09 2024-07-16 Gen-Probe Incorporated Quantification of polynucleotide analytes from dried samples
US20230117369A1 (en) 2020-03-04 2023-04-20 Gen-Probe Incorporated Compositions and methods for detecting sars-cov-2 nucleaic acid
CA3226812A1 (en) 2021-07-27 2023-02-02 Gen-Probe Incorporated Compositions and methods for detecting gastrointestinal pathogens
KR102544380B1 (ko) 2022-01-29 2023-06-16 (주)동방지퍼 지퍼용 슬라이더와 손잡이의 결착방법 및 이로 인해 제조된 지퍼
EP4282980A1 (en) 2022-05-23 2023-11-29 Mobidiag Oy Methods for amplifying a nucleic acid
WO2024054924A1 (en) 2022-09-08 2024-03-14 Gen-Probe Incorporated Method of detecting nucleic acid analytes using dual-specificity primers
EP4705516A1 (en) 2023-05-05 2026-03-11 Gen-Probe Incorporated Method and system for improving specificity of analyte detection using real-time nucleic acid amplification

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3116353B2 (ja) * 1986-11-24 2000-12-11 ジエン‐プローブ・インコーポレイテツド 非ウイルス微生物の検出及び／又は定量用核酸プローブ
IL86724A (en) * 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
US4994368A (en) * 1987-07-23 1991-02-19 Syntex (U.S.A.) Inc. Amplification method for polynucleotide assays
FI911152A7 (fi) * 1989-07-11 1991-03-07 Gen Probe Inc Nukleiinihapposekvenssin amplifikaatiomenetelmät
DE69118930T2 (de) * 1990-01-26 1997-01-09 Abbott Lab Verbessertes Verfahren zur Amplifikation von Nuklein säurezielsequenz, einsetzbar für die Polymerase und Ligasekettenreaktion
WO1992007957A1 (en) * 1990-10-31 1992-05-14 Cimino George D Methods and compositions for minimizing inhibition of nucleic acid amplification
US5169766A (en) * 1991-06-14 1992-12-08 Life Technologies, Inc. Amplification of nucleic acid molecules
US5521300A (en) * 1991-08-13 1996-05-28 Norval B. Galloway Oligonucleotides complementary to mycobacterial nucleic acids
JP4137996B2 (ja) * 1992-05-06 2008-08-20 ジェン−プローブ・インコーポレイテッド 核酸配列増幅方法，組成物及びキット

Also Published As

Publication number Publication date
ATE197479T1 (de) 2000-11-11
AU4792093A (en) 1994-03-03
AU6802796A (en) 1996-12-19
JP3860809B2 (ja) 2006-12-20
CA2141430C (en) 2009-05-12
JP4372837B2 (ja) 2009-11-25
KR100316498B1 (ko) 2002-06-20
DE69329636D1 (de) 2000-12-14
TW278099B (no) 1996-06-11
EP0587298B1 (en) 2000-11-08
EP0978570A3 (en) 2000-04-12
CA2141430A1 (en) 1994-02-17
KR950702999A (ko) 1995-08-23
EP0587298A2 (en) 1994-03-16
ES2277679T3 (es) 2007-07-16
DE69329636T2 (de) 2001-03-01
EP0587298A3 (en) 1995-08-30
JP2006238892A (ja) 2006-09-14
EP0978570A2 (en) 2000-02-09
EP0978570B1 (en) 2006-11-29
ATE346954T1 (de) 2006-12-15
JPH07509368A (ja) 1995-10-19
JP2004194662A (ja) 2004-07-15
AU700253B2 (en) 1998-12-24
WO1994003472A1 (en) 1994-02-17
AU670116B2 (en) 1996-07-04
DE69334092D1 (de) 2007-01-11
NO950381D0 (no) 1995-02-02
DE69334092T2 (de) 2007-07-05

Similar Documents

Publication Publication Date Title
NO950381D0 (no) Nukleinsyresekvens amplifikasjon
DK0519338T3 (da) Forbedrede fremgangsmåder til nukleinsyreamplifikation
ES2156861T3 (es) Secuenciacion ciclica de dna.
EP0674009A3 (en) Method and device for nucleic acid amplification.
PL325439A1 (en) Oligonucleotides, method of amplifying nuclein acid and set of means for acrrying out such amplification of nucleic acid
FR2690691B1 (fr) Procede d'amplification d'arn necessitant une seule etape de manipulation.
DE69122712D1 (de) Verfahren zur nukleinsäure hybridisierung und amplifizierung
RU94033149A (ru) Селективный ограничительный фрагмент амплификации: общий метод для днк "фингерпринтинга"
EP0328829A3 (en) Method for affinity assays using target amplification
ATE114651T1 (de) Alkynylamino-nukleotide.
ATE278013T1 (de) In vitro selektionsmethode
DE3873842D1 (de) Verfahren zur gen-amplifikation.
KR970701791A (ko) 등온 가닥 변위 핵산 증폭법(Isothermal Strand Displacement Nucleic Acid Amplification)
DE69708865D1 (de) Verfahren zur direkten sequenzierung während "template"-amplifikation
FI955619A0 (fi) Menetelmä nukleiinihappojen erityisen herkäksi detektoimiseksi
FI953079L (fi) DNA:n vahvistaminen
DK0587331T3 (da) Nukleinsyreprober til Chlamydia pneumoniae.
DK0840802T3 (da) Fremgangsmåde til sekvensering gennem oligomerhybridisering
DE69328951D1 (de) Nukleinsäuresonden für Mykobacterium Tuberkulosis
NO940658L (no) Nukleinsyre-polymerase-forökning
DE59814032D1 (de) Nucleinsäuremolekül, kit und verwendung
DE3781192D1 (de) Mikroorganismus, esterase und verfahren zu deren herstellung.
PT916659E (pt) Processo para a producao de formilimidazolos
DE69230345D1 (de) Nachweis von einem genort
DE3782288D1 (de) Verfahren zum waermebehandeln von rasch abgeschreckten fe-6,5% si-baendern.