ATE349514T1 - Chemisch modifizierte enzyme - Google Patents

Chemisch modifizierte enzyme

Info

Publication number: ATE349514T1
Authority: AT; Austria
Prior art keywords: modified enzymes; alkyl; substituted; replaced; chemically modified
Prior art date: 1996-11-26

Application number

AT97949562T

Other languages

English (en)

Inventor

Richard R Bott

Thomas P Graycar

Colin Mitchinson

Grace Desantis

J Bryan Jones

Original Assignee

Genencor Int

Univ Toronto

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-26

Filing date

1997-11-24

Publication date

2007-01-15

1997-11-24 Application filed by Genencor Int, Univ Toronto filed Critical Genencor Int

2007-01-15 Application granted granted Critical

2007-01-15 Publication of ATE349514T1 publication Critical patent/ATE349514T1/de

Links

102000004190 Enzymes Human genes 0.000 title abstract 6
108090000790 Enzymes Proteins 0.000 title abstract 6
125000000217 alkyl group Chemical group 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
125000003396 thiol group Chemical class [H]S* 0.000 abstract 2
MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract 1
ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 abstract 1
FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 abstract 1
MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
235000001014 amino acid Nutrition 0.000 abstract 1
229940024606 amino acid Drugs 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
239000003674 animal food additive Substances 0.000 abstract 1
229960001230 asparagine Drugs 0.000 abstract 1
235000009582 asparagine Nutrition 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
235000018417 cysteine Nutrition 0.000 abstract 1
XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 abstract 1
239000003599 detergent Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
229930182817 methionine Natural products 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
239000004753 textile Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38663—Stabilised liquid enzyme compositions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Detergent Compositions (AREA)
Enzymes And Modification Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Chemical Or Physical Treatment Of Fibers (AREA)

AT97949562T 1996-11-26 1997-11-24 Chemisch modifizierte enzyme ATE349514T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US75666496A	1996-11-26	1996-11-26

Publications (1)

Publication Number	Publication Date
ATE349514T1 true ATE349514T1 (de)	2007-01-15

Family

ID=25044504

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97949562T ATE349514T1 (de)	1996-11-26	1997-11-24	Chemisch modifizierte enzyme

Country Status (12)

Country	Link
US (1)	US6277617B1 (de)
EP (1)	EP0942962B1 (de)
JP (1)	JP2002506342A (de)
CN (1)	CN1246146A (de)
AT (1)	ATE349514T1 (de)
AU (1)	AU733082B2 (de)
CA (2)	CA2273079C (de)
DE (1)	DE69737148T2 (de)
DK (1)	DK0942962T3 (de)
ES (1)	ES2277364T3 (de)
NZ (1)	NZ336434A (de)
WO (1)	WO1998023732A2 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2368718T3 (es) *	1997-10-23	2011-11-21	Danisco Us Inc.	Variantes de subtilisina con múltiples sustituciones.
US6569663B1 (en)	1998-03-26	2003-05-27	The Procter & Gamble Company	Serine protease variants having amino acid substitutions
US6495136B1 (en)	1998-03-26	2002-12-17	The Procter & Gamble Company	Proteases having modified amino acid sequences conjugated to addition moieties
US6908757B1 (en)	1998-03-26	2005-06-21	The Procter & Gamble Company	Serine protease variants having amino acid deletions and substitutions
DE69939538D1 (de)	1998-07-02	2008-10-23	Univ Toronto	Mit einer kohlenhydratgruppe chemisch modifizierte proteine
WO2000028007A2 (en) *	1998-11-10	2000-05-18	Genencor International, Inc.	Chemically modified mutant serine hydrolases
AU2200100A (en)	1998-12-21	2000-07-12	Genencor International, Inc.	Chemically modified enzymes with multiple charged variants
EP1185302B1 (de)	1999-04-28	2013-07-24	Genencor International, Inc.	Spezifischer zielrichtung von katalytische antagoniste und deren verwendungen
US6627744B2 (en)	1999-07-02	2003-09-30	Genencor International, Inc.	Synthesis of glycodendrimer reagents
CN1373802A (zh)	1999-07-22	2002-10-09	宝洁公司	在特定表位区域具有氨基酸缺失和取代的枯草杆菌蛋白酶变体
BR0012660A (pt)	1999-07-22	2002-04-09	Procter & Gamble	Variante de protease tipo subtilisina; composição de limpeza; e composição de cuidado pessoal
EP1196547A2 (de) *	1999-07-22	2002-04-17	The Procter & Gamble Company	Proteasekonjugate mit sterisch geschützten epitopgebieten
MXPA02000842A (es)	1999-07-22	2002-07-30	Procter & Gamble	Conjugados de proteasa que tienen sitios de corte protegidos estericamente.
US6946128B1 (en)	1999-07-22	2005-09-20	The Procter & Gamble Company	Protease conjugates having sterically protected epitope regions
KR20030057529A (ko) *	2000-09-08	2003-07-04	그리폰 테라퓨틱스, 인코포레이티드	합성 적혈구생성 자극 단백질
ATE449840T1 (de)	2001-05-15	2009-12-15	Novozymes As	Alpha-amylasevariante mit veränderten eigenschaften
US20030157645A1 (en) *	2001-12-21	2003-08-21	Direvo Bio Tech Ag.	Subtilisin variants with improved characteristics
US20090060933A1 (en) *	2004-06-14	2009-03-05	Estell David A	Proteases producing an altered immunogenic response and methods of making and using the same
KR20100088675A (ko)	2007-11-05	2010-08-10	다니스코 유에스 인크.	변경된 특성을 지닌 바실러스 종 ｔｓ-23 알파-아밀라아제의 변이체
US8206966B2 (en)	2007-11-05	2012-06-26	Danisco Us Inc.	Alpha-amylase variants with altered properties
ITMI20072215A1 (it) *	2007-11-22	2009-05-23	Sulfidris S R L	Nuovi composti anticancro
AU2009212526A1 (en)	2008-02-04	2009-08-13	Danisco Us Inc.	TS23 alpha-amylase variants with altered properties
MX2010013113A (es)	2008-06-06	2010-12-21	Danisco Inc	Variantes de alfa-amilasa geobacillus stearothermophilus con propiedades mejoradas.
WO2010036515A1 (en)	2008-09-25	2010-04-01	Danisco Us Inc.	Alpha-amylase blends and methods for using said blends
EP2414515A2 (de)	2009-04-01	2012-02-08	Danisco US Inc.	Reinigungssystem mit einer alpha-amylase und einer protease
US9434932B2 (en)	2011-06-30	2016-09-06	Novozymes A/S	Alpha-amylase variants
DE102011118027A1 (de)	2011-09-12	2013-03-14	Henkel Ag & Co. Kgaa	Verfahren zur Anpassung eines Hydrolytischen Enzyms an eine das hydrolytische Enzym stabilisierende Komponente
US10400230B2 (en) *	2014-12-19	2019-09-03	Novozymes A/S	Protease variants and polynucleotides encoding same
CN106192395B (zh) *	2016-07-04	2018-09-07	浙江理工大学	改性棉织物表面增强纳米银抗菌棉织物耐洗性能的方法
CN115851670B (zh) *	2022-11-30	2024-04-12	山东龙昌动物保健品股份有限公司	木聚糖酶突变体及与杜仲叶提取物的复配制剂和在饲料添加剂的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1056187C (zh) *	1988-02-11	2000-09-06	金克克国际有限公司	新的蛋白水解酶及其在洗涤剂中的应用
DK97190D0 (da) *	1990-04-19	1990-04-19	Novo Nordisk As	Oxidationsstabile detergentenzymer
US5316935A (en)	1992-04-06	1994-05-31	California Institute Of Technology	Subtilisin variants suitable for hydrolysis and synthesis in organic media
US5837516A (en) *	1995-03-03	1998-11-17	Genentech, Inc.	Subtilisin variants capable of cleaving substrates containing basic residues

1997
- 1997-11-24 CN CN97181388A patent/CN1246146A/zh active Pending
- 1997-11-24 AU AU74173/98A patent/AU733082B2/en not_active Ceased
- 1997-11-24 DK DK97949562T patent/DK0942962T3/da active
- 1997-11-24 CA CA2273079A patent/CA2273079C/en not_active Expired - Lifetime
- 1997-11-24 NZ NZ336434A patent/NZ336434A/xx not_active IP Right Cessation
- 1997-11-24 EP EP97949562A patent/EP0942962B1/de not_active Expired - Lifetime
- 1997-11-24 WO PCT/US1997/021446 patent/WO1998023732A2/en not_active Ceased
- 1997-11-24 DE DE69737148T patent/DE69737148T2/de not_active Expired - Lifetime
- 1997-11-24 JP JP52478698A patent/JP2002506342A/ja active Pending
- 1997-11-24 AT AT97949562T patent/ATE349514T1/de not_active IP Right Cessation
- 1997-11-24 ES ES97949562T patent/ES2277364T3/es not_active Expired - Lifetime
- 1997-11-24 CA CA2763810A patent/CA2763810C/en not_active Expired - Lifetime
- 1997-11-25 US US08/978,509 patent/US6277617B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE69737148T2 (de)	2007-10-04
US6277617B1 (en)	2001-08-21
CN1246146A (zh)	2000-03-01
DE69737148D1 (de)	2007-02-08
NZ336434A (en)	2001-03-30
AU7417398A (en)	1998-06-22
AU733082B2 (en)	2001-05-03
JP2002506342A (ja)	2002-02-26
CA2273079A1 (en)	1998-06-04
CA2763810A1 (en)	1998-06-04
ES2277364T3 (es)	2007-07-01
WO1998023732A2 (en)	1998-06-04
DK0942962T3 (da)	2007-05-07
WO1998023732A3 (en)	1998-10-22
EP0942962A2 (de)	1999-09-22
CA2273079C (en)	2012-04-10
EP0942962B1 (de)	2006-12-27
CA2763810C (en)	2013-04-02

Legal Events

Date	Code	Title	Description
2007-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE349514T1 (de)	2007-01-15	Chemisch modifizierte enzyme
ATE233552T1 (de)	2003-03-15	Thiol-sulfonen als metalloproteinaseinhibitoren
NO990855D0 (no)	1999-02-23	Substituerte sykliske amin-metallprotease-inhibitorer
TR200003069T2 (tr)	2009-01-21	İkame edilmiş benzamidler, üretimi ve kullanımı
ATE326454T1 (de)	2006-06-15	Neue bernsteinsäure derivative als cysteine- protease-inhibitoren
ATE216360T1 (de)	2002-05-15	Sulfinsäurederivate und deren herstellung und verwendung
DE69432035D1 (de)	2003-02-27	Saccharinderivate als proteolytische Enzyminhibitoren
DE69941364D1 (de)	2009-10-15	Varianten eines lipolytischen enzyms
PE71599A1 (es)	1999-09-15	Inhibidores de proteasas
ATE235473T1 (de)	2003-04-15	Verfahren zur herstellung von triazolinthion- derivaten
HK1044754A1 (zh)	2002-11-01	含有烯烃基-和烯烃金属蛋白酶抑制剂
DE60221508D1 (de)	2007-09-13	Aminosäurederivate als hiv-protease-inhibitoren
ATE349543T1 (de)	2007-01-15	Verfahren, umfassend die indirekte elektrochemische regeneration von nad(p)h
DE69923676D1 (de)	2005-03-17	Bestimmte heteroaryl substituierte thiol inhibitoren von endothelin wechselnden enzymen
MY139322A (en)	2009-09-30	Method for producing 2-azetidinone derivative
ATE298325T1 (de)	2005-07-15	Verfahren zur herstellung von n-(4-hydroxyphenyl)-n'-(4'-aminophenyl)-piperaz ne
ATE330933T1 (de)	2006-07-15	Verfahren zur herstellung von optisch aktiven amino-alkoholen
MA24197A1 (fr)	1997-12-31	Nouvelles fungarrestines
DE69815380D1 (de)	2003-07-10	N,n'-bis (sulfonyl) hydrazine die als antineoplastische mittel nützlich sind
EP0934951A4 (de)	2003-01-02	Pflanzenzelluläre wachstumsfaktoren
DE59907569D1 (de)	2003-12-04	Verfahren zur herstellung von optisch aktiven 1- amino-4- (hydroxymethyl)- cyclopent-2- en-derivaten
TWI256383B (en)	2006-06-11	Anthraquinone compound
ATE238781T1 (de)	2003-05-15	Verwendung von katecholderivaten als proteinaseinhibitoren
BG106174A (en)	2003-06-30	Method for the production of highly purified monocomponent insulin