ATE349514T1 - Chemisch modifizierte enzyme - Google Patents

Chemisch modifizierte enzyme

Info

Publication number: ATE349514T1
Authority: AT; Austria
Prior art keywords: modified enzymes; alkyl; substituted; replaced; chemically modified
Prior art date: 1996-11-26

Application number

AT97949562T

Other languages

English (en)

Inventor

Richard R Bott

Thomas P Graycar

Colin Mitchinson

Grace Desantis

J Bryan Jones

Original Assignee

Genencor Int

Univ Toronto

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-26

Filing date

1997-11-24

Publication date

2007-01-15

1997-11-24 Application filed by Genencor Int, Univ Toronto filed Critical Genencor Int

2007-01-15 Application granted granted Critical

2007-01-15 Publication of ATE349514T1 publication Critical patent/ATE349514T1/de

Links

102000004190 Enzymes Human genes 0.000 title abstract 6
108090000790 Enzymes Proteins 0.000 title abstract 6
125000000217 alkyl group Chemical group 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
125000003396 thiol group Chemical class [H]S* 0.000 abstract 2
MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract 1
ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 abstract 1
FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 abstract 1
MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
235000001014 amino acid Nutrition 0.000 abstract 1
229940024606 amino acid Drugs 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
239000003674 animal food additive Substances 0.000 abstract 1
229960001230 asparagine Drugs 0.000 abstract 1
235000009582 asparagine Nutrition 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
235000018417 cysteine Nutrition 0.000 abstract 1
XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 abstract 1
239000003599 detergent Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
229930182817 methionine Natural products 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
239000004753 textile Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38663—Stabilised liquid enzyme compositions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Detergent Compositions (AREA)
Enzymes And Modification Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Chemical Or Physical Treatment Of Fibers (AREA)

AT97949562T 1996-11-26 1997-11-24 Chemisch modifizierte enzyme ATE349514T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US75666496A	1996-11-26	1996-11-26

Publications (1)

Publication Number	Publication Date
ATE349514T1 true ATE349514T1 (de)	2007-01-15

Family

ID=25044504

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97949562T ATE349514T1 (de)	1996-11-26	1997-11-24	Chemisch modifizierte enzyme

Country Status (12)

Country	Link
US (1)	US6277617B1 (de)
EP (1)	EP0942962B1 (de)
JP (1)	JP2002506342A (de)
CN (1)	CN1246146A (de)
AT (1)	ATE349514T1 (de)
AU (1)	AU733082B2 (de)
CA (2)	CA2273079C (de)
DE (1)	DE69737148T2 (de)
DK (1)	DK0942962T3 (de)
ES (1)	ES2277364T3 (de)
NZ (1)	NZ336434A (de)
WO (1)	WO1998023732A2 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2367505T3 (es) *	1997-10-23	2011-11-04	Danisco Us Inc.	Variantes de proteasa con sustituciones múltiples con carga neta alterada para usar en detergentes.
BR9909130A (pt)	1998-03-26	2000-12-19	Procter & Gamble	Variantes de protease de serina tendo substituições de amino-ácido
US6495136B1 (en)	1998-03-26	2002-12-17	The Procter & Gamble Company	Proteases having modified amino acid sequences conjugated to addition moieties
US6908757B1 (en)	1998-03-26	2005-06-21	The Procter & Gamble Company	Serine protease variants having amino acid deletions and substitutions
EP1093459B1 (de)	1998-07-02	2008-09-10	The Governing Council Of The University Of Toronto	Mit einer kohlenhydratgruppe chemisch modifizierte proteine
AU772427B2 (en) *	1998-11-10	2004-04-29	Genencor International, Inc.	Chemically modified mutant serine hydrolases show improved catalytic activity and chiral selectivity
DE69941223D1 (de)	1998-12-21	2009-09-17	Billig Fritz	Chemisch modifizierte enzymen mit mehrfachgeladenen varianten
KR20020057797A (ko)	1999-04-28	2002-07-12	더 거버닝 카운실 오브 더 유니버시티 오브 토론토	특이적으로 표적화된 촉매적 안타고니스트 및 그 용도
US6627744B2 (en)	1999-07-02	2003-09-30	Genencor International, Inc.	Synthesis of glycodendrimer reagents
BR0012694A (pt)	1999-07-22	2002-04-09	Procter & Gamble	Conjugado de protease, composição de limpeza e composição de tratamento pessoal
CA2376045A1 (en)	1999-07-22	2001-02-01	The Procter & Gamble Company	Subtilisin protease variants having amino acid substitutions in defined epitope regions
KR20020021397A (ko)	1999-07-22	2002-03-20	데이비드 엠 모이어	규정된 에피토프 영역에 아미노산 결실 및 치환을 갖는서브틸리신 프로테아제 변이체
US6946128B1 (en)	1999-07-22	2005-09-20	The Procter & Gamble Company	Protease conjugates having sterically protected epitope regions
KR20020021396A (ko) *	1999-07-22	2002-03-20	데이비드 엠 모이어	입체적으로 보호된 에피토프 영역을 갖는 프로테아제콘쥬게이트
ATE500838T1 (de) *	2000-09-08	2011-03-15	Amylin Pharmaceuticals Inc	ßPSEUDOß-NATIVE CHEMISCHE LIGATION
US7498158B2 (en)	2001-05-15	2009-03-03	Novozymes A/S	Alpha-amylase variant with altered properties
US20030157645A1 (en) *	2001-12-21	2003-08-21	Direvo Bio Tech Ag.	Subtilisin variants with improved characteristics
US20090060933A1 (en) *	2004-06-14	2009-03-05	Estell David A	Proteases producing an altered immunogenic response and methods of making and using the same
EP2215110B1 (de)	2007-11-05	2025-07-16	Danisco US Inc.	Alpha-amylase-varianten mit veränderten eigenschaften
JP5520828B2 (ja)	2007-11-05	2014-06-11	ダニスコ・ユーエス・インク	改変される特徴を有するバシルス種（Ｂａｃｉｌｌｕｓｓｐ．）ＴＳ‐２３アルファ‐アミラーゼ変異体
ITMI20072215A1 (it) *	2007-11-22	2009-05-23	Sulfidris S R L	Nuovi composti anticancro
CA2713582C (en)	2008-02-04	2017-02-21	Danisco Us Inc.	Ts23 alpha-amylase variants with altered properties
WO2009149130A2 (en)	2008-06-06	2009-12-10	Danisco Us Inc.	Geobacillus stearothermophilus alpha-amylase (amys) variants with improved properties
EP2337837B2 (de)	2008-09-25	2016-10-26	Danisco US Inc.	Alpha amylase gemische und methoden zu deren nutzung
CA2757343A1 (en)	2009-04-01	2010-10-07	Danisco Us Inc.	Compositions and methods comprising alpha-amylase variants with altered properties
ES2834102T3 (es)	2011-06-30	2021-06-16	Novozymes As	Variantes de alfa-amilasa
DE102011118027A1 (de) *	2011-09-12	2013-03-14	Henkel Ag & Co. Kgaa	Verfahren zur Anpassung eines Hydrolytischen Enzyms an eine das hydrolytische Enzym stabilisierende Komponente
WO2016097352A1 (en) *	2014-12-19	2016-06-23	Novozymes A/S	Protease variants and polynucleotides encoding same
CN106192395B (zh) *	2016-07-04	2018-09-07	浙江理工大学	改性棉织物表面增强纳米银抗菌棉织物耐洗性能的方法
CN115851670B (zh) *	2022-11-30	2024-04-12	山东龙昌动物保健品股份有限公司	木聚糖酶突变体及与杜仲叶提取物的复配制剂和在饲料添加剂的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1056187C (zh) *	1988-02-11	2000-09-06	金克克国际有限公司	新的蛋白水解酶及其在洗涤剂中的应用
DK97190D0 (da) *	1990-04-19	1990-04-19	Novo Nordisk As	Oxidationsstabile detergentenzymer
US5316935A (en)	1992-04-06	1994-05-31	California Institute Of Technology	Subtilisin variants suitable for hydrolysis and synthesis in organic media
US5837516A (en) *	1995-03-03	1998-11-17	Genentech, Inc.	Subtilisin variants capable of cleaving substrates containing basic residues

1997
- 1997-11-24 CA CA2273079A patent/CA2273079C/en not_active Expired - Lifetime
- 1997-11-24 EP EP97949562A patent/EP0942962B1/de not_active Expired - Lifetime
- 1997-11-24 CN CN97181388A patent/CN1246146A/zh active Pending
- 1997-11-24 CA CA2763810A patent/CA2763810C/en not_active Expired - Lifetime
- 1997-11-24 ES ES97949562T patent/ES2277364T3/es not_active Expired - Lifetime
- 1997-11-24 DK DK97949562T patent/DK0942962T3/da active
- 1997-11-24 NZ NZ336434A patent/NZ336434A/xx not_active IP Right Cessation
- 1997-11-24 WO PCT/US1997/021446 patent/WO1998023732A2/en not_active Ceased
- 1997-11-24 AU AU74173/98A patent/AU733082B2/en not_active Ceased
- 1997-11-24 JP JP52478698A patent/JP2002506342A/ja active Pending
- 1997-11-24 AT AT97949562T patent/ATE349514T1/de not_active IP Right Cessation
- 1997-11-24 DE DE69737148T patent/DE69737148T2/de not_active Expired - Lifetime
- 1997-11-25 US US08/978,509 patent/US6277617B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DK0942962T3 (da)	2007-05-07
AU7417398A (en)	1998-06-22
AU733082B2 (en)	2001-05-03
CA2763810A1 (en)	1998-06-04
JP2002506342A (ja)	2002-02-26
WO1998023732A2 (en)	1998-06-04
DE69737148D1 (de)	2007-02-08
CA2273079C (en)	2012-04-10
NZ336434A (en)	2001-03-30
EP0942962B1 (de)	2006-12-27
CA2273079A1 (en)	1998-06-04
EP0942962A2 (de)	1999-09-22
CA2763810C (en)	2013-04-02
DE69737148T2 (de)	2007-10-04
CN1246146A (zh)	2000-03-01
WO1998023732A3 (en)	1998-10-22
US6277617B1 (en)	2001-08-21
ES2277364T3 (es)	2007-07-01

Legal Events

Date	Code	Title	Description
2007-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69737148D1 (de)	2007-02-08	Chemisch modifizierte enzyme
ATE233552T1 (de)	2003-03-15	Thiol-sulfonen als metalloproteinaseinhibitoren
NO990855L (no)	1999-04-23	Substituerte sykliske amin-metallprotease-inhibitorer
TR200003069T2 (tr)	2009-01-21	İkame edilmiş benzamidler, üretimi ve kullanımı
ATE326454T1 (de)	2006-06-15	Neue bernsteinsäure derivative als cysteine- protease-inhibitoren
ATE216360T1 (de)	2002-05-15	Sulfinsäurederivate und deren herstellung und verwendung
ATE103632T1 (de)	1994-04-15	Enzymatische waschmittelzusammensetzung und verfahren zum stabilisieren der enzyme.
ATE340857T1 (de)	2006-10-15	Verfahren zur herstellung von l-aminosäuren durch erhöhung des zellulären nadph
ATE441704T1 (de)	2009-09-15	Varianten eines lipolytischen enzyms
DE10345772A1 (de)	2005-04-21	Verfahren zur Herstellung von 3-Methylamino-1-(thien-2-yl)-propan-1-ol
PE71599A1 (es)	1999-09-15	Inhibidores de proteasas
DE59807672D1 (de)	2003-04-30	Verfahren zur herstellung von triazolinthion-derivaten
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DE60221508D1 (de)	2007-09-13	Aminosäurederivate als hiv-protease-inhibitoren
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DE69923676D1 (de)	2005-03-17	Bestimmte heteroaryl substituierte thiol inhibitoren von endothelin wechselnden enzymen
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ATE298325T1 (de)	2005-07-15	Verfahren zur herstellung von n-(4-hydroxyphenyl)-n'-(4'-aminophenyl)-piperaz ne
DE60028927D1 (de)	2006-08-03	Verfahren zur herstellung von optisch aktiven amino-alkoholen
TR200002755T2 (tr)	2002-05-21	Aracı hazırlamak için süreç.
DE69815380D1 (de)	2003-07-10	N,n'-bis (sulfonyl) hydrazine die als antineoplastische mittel nützlich sind
ATE253125T1 (de)	2003-11-15	Verfahren zur herstellung von optisch aktiven 1- amino-4- (hydroxymethyl)- cyclopent-2- en- derivaten
DE69731895D1 (de)	2005-01-13	Pflanzenzelluläre wachstumsfaktoren
ATE470700T1 (de)	2010-06-15	Bazillus zelle für die herstellung von proteinen
TWI256383B (en)	2006-06-11	Anthraquinone compound