ATE350013T1 - Nanopartikelzusammensetzungen enthaltend insulin - Google Patents
Nanopartikelzusammensetzungen enthaltend insulinInfo
- Publication number
- ATE350013T1 ATE350013T1 AT02775863T AT02775863T ATE350013T1 AT E350013 T1 ATE350013 T1 AT E350013T1 AT 02775863 T AT02775863 T AT 02775863T AT 02775863 T AT02775863 T AT 02775863T AT E350013 T1 ATE350013 T1 AT E350013T1
- Authority
- AT
- Austria
- Prior art keywords
- insulin
- compositions
- compositions containing
- nanoparticle compositions
- containing insulin
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 12
- 102000004877 Insulin Human genes 0.000 title abstract 6
- 108090001061 Insulin Proteins 0.000 title abstract 6
- 229940125396 insulin Drugs 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 6
- 239000002105 nanoparticle Substances 0.000 title 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32345901P | 2001-09-19 | 2001-09-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE350013T1 true ATE350013T1 (de) | 2007-01-15 |
Family
ID=23259284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02775863T ATE350013T1 (de) | 2001-09-19 | 2002-09-19 | Nanopartikelzusammensetzungen enthaltend insulin |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20030095928A1 (de) |
| EP (1) | EP1429731B1 (de) |
| JP (2) | JP4464129B2 (de) |
| AT (1) | ATE350013T1 (de) |
| CA (1) | CA2460867C (de) |
| CY (1) | CY1106420T1 (de) |
| DE (1) | DE60217367T2 (de) |
| DK (1) | DK1429731T3 (de) |
| ES (1) | ES2280582T3 (de) |
| PT (1) | PT1429731E (de) |
| WO (1) | WO2003024425A1 (de) |
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-
2002
- 2002-09-19 PT PT02775863T patent/PT1429731E/pt unknown
- 2002-09-19 ES ES02775863T patent/ES2280582T3/es not_active Expired - Lifetime
- 2002-09-19 WO PCT/US2002/029679 patent/WO2003024425A1/en not_active Ceased
- 2002-09-19 DE DE60217367T patent/DE60217367T2/de not_active Expired - Lifetime
- 2002-09-19 JP JP2003528522A patent/JP4464129B2/ja not_active Expired - Fee Related
- 2002-09-19 US US10/246,751 patent/US20030095928A1/en not_active Abandoned
- 2002-09-19 CA CA2460867A patent/CA2460867C/en not_active Expired - Fee Related
- 2002-09-19 EP EP02775863A patent/EP1429731B1/de not_active Expired - Lifetime
- 2002-09-19 AT AT02775863T patent/ATE350013T1/de active
- 2002-09-19 DK DK02775863T patent/DK1429731T3/da active
-
2007
- 2007-01-26 US US11/698,151 patent/US20070122486A1/en not_active Abandoned
- 2007-03-29 CY CY20071100434T patent/CY1106420T1/el unknown
-
2009
- 2009-08-24 JP JP2009193163A patent/JP2010006826A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1429731B1 (de) | 2007-01-03 |
| JP2010006826A (ja) | 2010-01-14 |
| CA2460867C (en) | 2011-04-12 |
| US20030095928A1 (en) | 2003-05-22 |
| EP1429731A1 (de) | 2004-06-23 |
| ES2280582T3 (es) | 2007-09-16 |
| US20070122486A1 (en) | 2007-05-31 |
| JP4464129B2 (ja) | 2010-05-19 |
| CY1106420T1 (el) | 2011-10-12 |
| WO2003024425A1 (en) | 2003-03-27 |
| CA2460867A1 (en) | 2003-03-27 |
| PT1429731E (pt) | 2007-04-30 |
| DK1429731T3 (da) | 2007-05-14 |
| JP2005511507A (ja) | 2005-04-28 |
| DE60217367D1 (de) | 2007-02-15 |
| DE60217367T2 (de) | 2007-10-18 |
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