ATE350060T1 - Mittel zur vorbeugung oder behandlung von pankreatitis die anti-il-6 receptor antikörper als aktive komponente enthalten - Google Patents
Mittel zur vorbeugung oder behandlung von pankreatitis die anti-il-6 receptor antikörper als aktive komponente enthaltenInfo
- Publication number
- ATE350060T1 ATE350060T1 AT99938591T AT99938591T ATE350060T1 AT E350060 T1 ATE350060 T1 AT E350060T1 AT 99938591 T AT99938591 T AT 99938591T AT 99938591 T AT99938591 T AT 99938591T AT E350060 T1 ATE350060 T1 AT E350060T1
- Authority
- AT
- Austria
- Prior art keywords
- agents
- preventing
- active component
- receptor antibodies
- contain anti
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/248—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25179698 | 1998-08-24 | ||
| JP5430299 | 1999-03-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE350060T1 true ATE350060T1 (de) | 2007-01-15 |
Family
ID=26395047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99938591T ATE350060T1 (de) | 1998-08-24 | 1999-08-23 | Mittel zur vorbeugung oder behandlung von pankreatitis die anti-il-6 receptor antikörper als aktive komponente enthalten |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8440196B1 (de) |
| EP (1) | EP1108435B1 (de) |
| JP (1) | JP4711507B2 (de) |
| AT (1) | ATE350060T1 (de) |
| AU (1) | AU757261B2 (de) |
| CA (1) | CA2341239C (de) |
| DE (1) | DE69934698T2 (de) |
| DK (1) | DK1108435T3 (de) |
| ES (1) | ES2276525T3 (de) |
| PT (1) | PT1108435E (de) |
| WO (1) | WO2000010607A1 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU736282B2 (en) | 1997-03-21 | 2001-07-26 | Chugai Seiyaku Kabushiki Kaisha | A preventive or therapeutic agent for sensitized T cell- mediated diseases comprising IL-6 antagonist as an active ingredient |
| UA80091C2 (en) | 2001-04-02 | 2007-08-27 | Chugai Pharmaceutical Co Ltd | Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist |
| WO2003068260A1 (fr) | 2002-02-14 | 2003-08-21 | Chugai Seiyaku Kabushiki Kaisha | Produits pharmaceutiques en solution contenant des anticorps |
| GB2401040A (en) | 2003-04-28 | 2004-11-03 | Chugai Pharmaceutical Co Ltd | Method for treating interleukin-6 related diseases |
| WO2005028514A1 (en) * | 2003-09-22 | 2005-03-31 | Biovation Gmbh & Co. Kg. | Use of a compound for reducing the biological effectiveness of il-6 |
| AR048335A1 (es) | 2004-03-24 | 2006-04-19 | Chugai Pharmaceutical Co Ltd | Agentes terapeuticos para trastornos del oido interno que contienen un antagonista de il- 6 como un ingrediente activo |
| JPWO2005090405A1 (ja) | 2004-03-24 | 2008-04-17 | 中外製薬株式会社 | インターロイキン−６受容体に対するヒト型化抗体のサブタイプ |
| RU2446826C2 (ru) * | 2005-10-14 | 2012-04-10 | Фукуока Юниверсити | Агенты для подавления повреждения трансплантированных островков после трансплантации островков |
| JP5191235B2 (ja) | 2005-10-21 | 2013-05-08 | 中外製薬株式会社 | 心疾患治療剤 |
| AR057582A1 (es) | 2005-11-15 | 2007-12-05 | Nat Hospital Organization | Agentes para suprimir la induccion de linfocitos t citotoxicos |
| AR059213A1 (es) | 2006-01-27 | 2008-03-19 | Univ Keio | Agentes terapeuticos para enfermedades que involucran neovascularizacion coroidal |
| CA2648644C (en) | 2006-04-07 | 2016-01-05 | Osaka University | Muscle regeneration promoter |
| US8080248B2 (en) | 2006-06-02 | 2011-12-20 | Regeneron Pharmaceuticals, Inc. | Method of treating rheumatoid arthritis with an IL-6R antibody |
| RS52176B (sr) | 2006-06-02 | 2012-08-31 | Regeneron Pharmaceuticals Inc. | Antitela visokog afiniteta prema humanom il-6 receptoru |
| BRPI0715115A2 (pt) | 2006-08-03 | 2013-06-04 | Vaccinex Inc | anticorpo monoclonal isolado, molÉcula de Ácido nucleico isolada, vetor de expressço, cÉlula hospedeira, mÉtodos para tratar uma doenÇa, e para produzir um anticorpo monoclonal isolado, uso do anticorpo monoclonal isolado, e, composiÇço farmacÊutica |
| JP2010095445A (ja) * | 2006-12-27 | 2010-04-30 | Tokyo Medical & Dental Univ | Ｉｌ−６アンタゴニストを有効成分とする炎症性筋疾患治療剤 |
| KR101508019B1 (ko) | 2007-01-23 | 2015-04-06 | 고쿠리츠 다이가쿠 호우징 신슈 다이가쿠 | 만성 거부반응 억제제 |
| US9981415B2 (en) | 2007-09-10 | 2018-05-29 | Ehc Canada, Inc. | Method and apparatus for extrusion of thermoplastic handrail |
| PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| AU2009246430B2 (en) | 2008-05-13 | 2015-07-02 | Novimmune S.A. | Anti-IL-6/IL-6R antibodies and methods of use thereof |
| US10717781B2 (en) | 2008-06-05 | 2020-07-21 | National Cancer Center | Neuroinvasion inhibitor |
| US8188235B2 (en) | 2008-06-18 | 2012-05-29 | Pfizer Inc. | Antibodies to IL-6 and their uses |
| KR101913109B1 (ko) | 2009-03-18 | 2018-10-31 | 리스버로직스 코퍼레이션 | 신규한 소염제 |
| DK2421533T3 (en) | 2009-04-22 | 2019-01-07 | Resverlogix Corp | Hitherto unknown anti-inflammatory agents |
| EP4406615A3 (de) * | 2009-10-26 | 2024-12-11 | F. Hoffmann-La Roche AG | Verfahren zur herstellung eines glykosylierten immunglobulins |
| JO3417B1 (ar) | 2010-01-08 | 2019-10-20 | Regeneron Pharma | الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r |
| JP5904552B2 (ja) | 2010-05-28 | 2016-04-13 | 国立研究開発法人国立がん研究センター | 膵癌治療剤 |
| EP4115906A1 (de) | 2010-05-28 | 2023-01-11 | Chugai Seiyaku Kabushiki Kaisha | Verstärker der antitumor t-zellenantwort |
| EP2638067A2 (de) | 2010-11-08 | 2013-09-18 | Genentech, Inc. | Subkutan verabreichter anti-il-6-rezeptorantikörper |
| WO2012067150A1 (ja) * | 2010-11-16 | 2012-05-24 | 三菱化学株式会社 | Interleukin-6 receptor subunit beta蛋白質による脳梗塞の検査方法 |
| TWI589299B (zh) | 2011-10-11 | 2017-07-01 | 再生元醫藥公司 | 用於治療類風濕性關節炎之組成物及其使用方法 |
| KR101487935B1 (ko) | 2012-05-21 | 2015-02-02 | 한국생명공학연구원 | 곰보배추의 추출물 또는 이의 분획물을 유효성분으로 포함하는, stat3 매개 질환의 예방 또는 치료용 약학적 조성물 |
| KR102248581B1 (ko) | 2013-07-04 | 2021-05-06 | 에프. 호프만-라 로슈 아게 | 혈청 샘플 중 항-약물 항체를 검출하기 위한 간섭-억제된 면역분석 |
| US9017678B1 (en) | 2014-07-15 | 2015-04-28 | Kymab Limited | Method of treating rheumatoid arthritis using antibody to IL6R |
| JP6903585B2 (ja) | 2015-03-13 | 2021-07-14 | レスバーロジックス コーポレイション | 補体関連疾患の治療のための組成物および治療方法 |
| KR102140861B1 (ko) | 2015-05-07 | 2020-08-03 | 이에이치씨 캐나다, 인크. | 향상된 기계적 성질을 갖는 소형 복합체 핸드레일 |
| EP3305325B1 (de) | 2015-06-04 | 2025-07-30 | National Center of Neurology and Psychiatry | Wirkstoff zur therapie von geisteskrankheiten mit il-6-hemmer als wirkstoff |
| CN107708960B (zh) | 2015-06-19 | 2020-08-04 | Ehc加拿大股份公司 | 用于挤出热塑性扶手的方法和设备 |
| WO2017147169A1 (en) | 2016-02-22 | 2017-08-31 | Ohio State Innovation Foundation | Chemoprevention using controlled-release formulations of anti-interleukin 6 agents, synthetic vitamin a analogues or metabolites, and estradiol metabolites |
| WO2018112237A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor |
| WO2018112232A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor released using an ingestible device |
| EP3554541B1 (de) | 2016-12-14 | 2023-06-07 | Biora Therapeutics, Inc. | Behandlung einer erkrankung des gastrointestinaltraktes mit einem chemokin/chemokin-rezeptor-inhibitor |
| EP3596175A4 (de) | 2017-03-17 | 2021-01-13 | The Ohio State Innovation Foundation | Nanopartikel zur abgabe von chemopräventiven mitteln |
| US20210138213A1 (en) | 2017-03-30 | 2021-05-13 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| EP3620531A4 (de) | 2017-05-02 | 2021-03-17 | National Center of Neurology and Psychiatry | Verfahren zur vorhersage und beurteilung der therapeutischen wirkung bei erkrankungen im zusammenhang mit il-6 und neutrophilen |
| US11692037B2 (en) | 2017-10-20 | 2023-07-04 | Hyogo College Of Medicine | Anti-IL-6 receptor antibody-containing medicinal composition for preventing post-surgical adhesion |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| WO2019246271A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor |
| WO2019246317A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease or condition in a tissue originating from the endoderm |
| TW202521583A (zh) | 2019-01-31 | 2025-06-01 | 法商賽諾菲生物技術公司 | 用於治療幼年原發性關節炎之組成物及方法 |
| WO2020201362A2 (en) | 2019-04-02 | 2020-10-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of predicting and preventing cancer in patients having premalignant lesions |
| MA55760A (fr) | 2019-04-24 | 2022-03-02 | Regeneron Pharma | Procédés de diagnostic et de traitement de la polyarthrite rhumatoïde |
| JP2022534794A (ja) | 2019-06-04 | 2022-08-03 | サノフィ・バイオテクノロジー | 関節リウマチを有する対象における疼痛を治療するための組成物および方法 |
| AR131388A1 (es) | 2022-12-15 | 2025-03-12 | Univ Aarhus | Activación sintética de receptores transmembrana multiméricos |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2898040B2 (ja) | 1990-01-26 | 1999-05-31 | 忠三 岸本 | ｇｐ１３０蛋白質に対する抗体 |
| US5210075A (en) | 1990-02-16 | 1993-05-11 | Tanabe Seiyaku Co., Ltd. | Interleukin 6 antagonist peptides |
| ES2134212T3 (es) * | 1991-04-25 | 1999-10-01 | Chugai Pharmaceutical Co Ltd | Anticuerpo humano reconstituido contra el receptor de la interleuquina 6 humano. |
| JPH05304986A (ja) | 1992-04-28 | 1993-11-19 | Tosoh Corp | ｇｐ１３０蛋白質に対するモノクロ−ナル抗体 |
| JP3525221B2 (ja) * | 1993-02-17 | 2004-05-10 | 味の素株式会社 | 免疫抑制剤 |
| WO1996012503A1 (en) * | 1994-10-21 | 1996-05-02 | Chugai Seiyaku Kabushiki Kaisha | Remedy for diseases caused by il-6 production |
| IT1274350B (it) | 1994-12-06 | 1997-07-17 | Angeletti P Ist Richerche Bio | Antagonisti di interleuchina-6(il-6) che consistono di forme solubili del ricettore alfa di il-6, mutate nell'interfaccia che si lega a gp 130 |
| IT1274782B (it) | 1994-12-14 | 1997-07-24 | Angeletti P Ist Richerche Bio | Metodo per selezionare superagonisti, antagonisti e superantagonisti di ormoni del cui complesso recettoriale fa parte gp 130 |
| WO1996040966A1 (en) | 1995-06-07 | 1996-12-19 | Private Biologicals Corporation | Compositions and methods of treating il-6 associated diseases |
-
1999
- 1999-08-23 WO PCT/JP1999/004533 patent/WO2000010607A1/ja not_active Ceased
- 1999-08-23 AU AU53049/99A patent/AU757261B2/en not_active Ceased
- 1999-08-23 AT AT99938591T patent/ATE350060T1/de active
- 1999-08-23 DK DK99938591T patent/DK1108435T3/da active
- 1999-08-23 EP EP99938591A patent/EP1108435B1/de not_active Expired - Lifetime
- 1999-08-23 JP JP2000565927A patent/JP4711507B2/ja not_active Expired - Fee Related
- 1999-08-23 DE DE69934698T patent/DE69934698T2/de not_active Expired - Lifetime
- 1999-08-23 US US09/762,550 patent/US8440196B1/en not_active Expired - Fee Related
- 1999-08-23 ES ES99938591T patent/ES2276525T3/es not_active Expired - Lifetime
- 1999-08-23 PT PT99938591T patent/PT1108435E/pt unknown
- 1999-08-23 CA CA2341239A patent/CA2341239C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU757261B2 (en) | 2003-02-13 |
| CA2341239C (en) | 2011-01-04 |
| CA2341239A1 (en) | 2000-03-02 |
| DE69934698T2 (de) | 2007-10-04 |
| US8440196B1 (en) | 2013-05-14 |
| EP1108435A1 (de) | 2001-06-20 |
| EP1108435B1 (de) | 2007-01-03 |
| EP1108435A4 (de) | 2002-05-08 |
| AU5304999A (en) | 2000-03-14 |
| DE69934698D1 (de) | 2007-02-15 |
| WO2000010607A1 (en) | 2000-03-02 |
| PT1108435E (pt) | 2007-04-30 |
| JP4711507B2 (ja) | 2011-06-29 |
| ES2276525T3 (es) | 2007-06-16 |
| DK1108435T3 (da) | 2007-02-05 |
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| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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