ATE351905T1 - Mitogene regulatoren - Google Patents

Mitogene regulatoren

Info

Publication number
ATE351905T1
ATE351905T1 AT99962738T AT99962738T ATE351905T1 AT E351905 T1 ATE351905 T1 AT E351905T1 AT 99962738 T AT99962738 T AT 99962738T AT 99962738 T AT99962738 T AT 99962738T AT E351905 T1 ATE351905 T1 AT E351905T1
Authority
AT
Austria
Prior art keywords
present
proteins
genes
activity
mitogene
Prior art date
Application number
AT99962738T
Other languages
English (en)
Inventor
J David Lambeth
Bernard P Lassegue
Kathy K Griendling
Rebecca S Arnold
Cheng Guangjie
Original Assignee
Univ Emory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Emory filed Critical Univ Emory
Application granted granted Critical
Publication of ATE351905T1 publication Critical patent/ATE351905T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Saccharide Compounds (AREA)
AT99962738T 1998-11-10 1999-11-10 Mitogene regulatoren ATE351905T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10791198P 1998-11-10 1998-11-10
US14933299P 1999-08-17 1999-08-17
US15124299P 1999-08-27 1999-08-27

Publications (1)

Publication Number Publication Date
ATE351905T1 true ATE351905T1 (de) 2007-02-15

Family

ID=27380381

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99962738T ATE351905T1 (de) 1998-11-10 1999-11-10 Mitogene regulatoren

Country Status (8)

Country Link
US (5) US6620603B1 (de)
EP (1) EP1131430B1 (de)
AT (1) ATE351905T1 (de)
AU (1) AU777187B2 (de)
CA (1) CA2350776C (de)
DE (1) DE69934903T2 (de)
ES (1) ES2279647T3 (de)
WO (1) WO2000028031A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858386B1 (en) 1998-05-21 2005-02-22 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating colon cancer
US6949339B1 (en) 1998-05-21 2005-09-27 Diadexus, Inc. Method of diagnosing, monitoring, and staging colon cancer
DE69934903T2 (de) 1998-11-10 2007-10-18 Emory University Mitogene regulatoren
CA2409068A1 (en) * 2000-05-15 2001-11-22 Emory University Novel dual oxidases as mitogenic and endocrine regulators
EP1287029A2 (de) * 2000-06-09 2003-03-05 Corixa Corporation Zusammensetzungen und verfahren zur therapie und diagnose von dickdarmkrebs
JP2004537981A (ja) 2000-11-16 2004-12-24 エモリー・ユニバーシティ マイトジェンオキシゲナーゼ調節因子
CA2480619A1 (en) 2002-06-06 2003-12-18 Masakatsu Kawakami Novel oxidase
EP1556079A2 (de) * 2002-07-16 2005-07-27 Emory University Regulatorisches protein für nox-enzyme
WO2004091647A1 (en) 2003-04-07 2004-10-28 The Board Of Trustees Of The Leland Stanford Junior University Compositions of active wnt protein
US20050233390A1 (en) * 2003-04-09 2005-10-20 Allen John W Device including a proteinaceous factor, a recombinant proteinaceous factor, and a nucleotide sequence encoding the proteinaceous factor
EP1602926A1 (de) 2004-06-04 2005-12-07 University of Geneva Neue Mittel und Verfahren zur Behandlung von Gehörverlust oder Tinnitus
US7825099B2 (en) * 2006-01-20 2010-11-02 Quark Pharmaceuticals, Inc. Treatment or prevention of oto-pathologies by inhibition of pro-apoptotic genes
WO2008152636A2 (en) * 2007-06-15 2008-12-18 Quark Pharmaceuticals, Inc. Compositions and methods for inhibiting nadph oxidase expression
WO2010080452A2 (en) 2008-12-18 2010-07-15 Quark Pharmaceuticals, Inc. siRNA COMPOUNDS AND METHODS OF USE THEREOF
US9951102B2 (en) * 2014-06-18 2018-04-24 University Of Iowa Research Foundation Peptide inhibitor of Nox1 NADPH oxidase

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US44783A (en) * 1864-10-25 Improvement in water-closet cocks
US109690A (en) * 1870-11-29 Improvement in stretching-frames
FR2437213A1 (fr) * 1978-09-28 1980-04-25 Cm Ind Produits cytotoxiques formes par liaison covalente de la chaine a de la ricine avec un anticorps et leur procede de preparation
DE3519404A1 (de) 1984-06-07 1985-12-12 Marginvest S.A. Holding, Luxemburg/Luxembourg Verfahren zur herstellung eines absorptions- und adsorptionsmittels, sowie nach diesem verfahren hergestelltes absorptions- und adsorptionsmittel
US5593966A (en) 1989-03-31 1997-01-14 The United States Of America As Represented By The Department Of Health And Human Services Peptide derivatives of cytochrome b558 and their use as medicaments
US5191066A (en) * 1990-12-07 1993-03-02 Abbott Laboratories Site-specific conjugation of immunoglobulins and detectable labels
RO116459B1 (ro) * 1991-07-25 2001-02-28 Idec Pharma Corp Compozitie imunogena
WO1996039419A1 (en) 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Colon specific genes and proteins
US5985270A (en) 1995-09-13 1999-11-16 Fordham University Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes
US6602659B1 (en) 1996-05-03 2003-08-05 Thomas Jefferson University Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof
WO1998044133A1 (en) 1997-03-31 1998-10-08 Abbott Laboratories Reagents and methods useful for detecting diseases of the gastrointestinal tract
EP0973944A1 (de) 1997-03-31 2000-01-26 Abbott Laboratories Reagentien und verfahren zur erkennung von krankheiten des gastrointestinaltraktes
EP1009766A4 (de) 1997-07-01 2003-04-09 Human Genome Sciences 19 menschlisch, sekretierte proteine
US5932445A (en) 1997-11-07 1999-08-03 Incyte Pharmaceuticals, Inc. Signal peptide-containing proteins
WO1999025828A1 (en) 1997-11-19 1999-05-27 Zymogenetics, Inc. A human 2-19 protein homologue, z219c
US20030044783A1 (en) * 2000-03-09 2003-03-06 Williams Lewis T. Human genes and gene expression products
US5929033A (en) * 1998-02-10 1999-07-27 Incyte Pharmaceuticals, Inc. Extracellular mucous matrix glycoprotein
US6245550B1 (en) 1998-03-20 2001-06-12 Smithkline Beecham Corporation Cytokine family member EF-7
CA2319089A1 (en) 1998-04-09 1999-10-21 Genset S.A. 5' ests and encoded human proteins
DE19820190A1 (de) 1998-04-28 1999-11-04 Metagen Gesellschaft Fuer Genomforschung Mbh Menschliche Nukleinsäuresequenzen aus Pankreas-Tumor
US6858386B1 (en) * 1998-05-21 2005-02-22 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating colon cancer
DE69929785T2 (de) 1998-05-21 2006-07-20 Diadexus, Inc., South San Francisco Verfahren zur Diagnose, Erkennung, und Einstufung von Dickdarmkrebs
CA2328895A1 (en) 1998-06-02 1999-12-09 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2002525031A (ja) 1998-08-04 2002-08-13 ダイアデクスアス・インコーポレーテッド 大腸癌の診断、監視、病期決定、画像処理及び治療の新規方法
NZ531664A (en) 1998-09-01 2005-07-29 Genentech Inc Pro1317 polypeptides and sequences thereof with homology to the semaphorin B glycoprotein family
DE69934903T2 (de) 1998-11-10 2007-10-18 Emory University Mitogene regulatoren
JP3695642B2 (ja) 1998-12-01 2005-09-14 ジェネンテック・インコーポレーテッド 血管形成及び心臓血管新生の促進又は阻害
EP1144632A3 (de) 1998-12-23 2001-11-07 Corixa Corporation Verbindungen zur immunotherapie und diagnose von dickdarmkrebs und verfahren zu ihrer anwendung
CA2384713A1 (en) * 1999-09-29 2001-04-05 Human Genome Sciences, Inc. Colon and colon cancer associated polynucleotides and polypeptides
CA2412223A1 (en) 2000-06-09 2001-12-20 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer

Also Published As

Publication number Publication date
WO2000028031A8 (en) 2000-07-20
EP1131430B1 (de) 2007-01-17
CA2350776C (en) 2011-05-03
US7247709B2 (en) 2007-07-24
ES2279647T3 (es) 2007-08-16
US20030157678A1 (en) 2003-08-21
WO2000028031A2 (en) 2000-05-18
US7045351B2 (en) 2006-05-16
DE69934903T2 (de) 2007-10-18
US20050089844A1 (en) 2005-04-28
US6620603B1 (en) 2003-09-16
EP1131430A2 (de) 2001-09-12
DE69934903D1 (de) 2007-03-08
AU1911800A (en) 2000-05-29
AU777187B2 (en) 2004-10-07
US20060160143A1 (en) 2006-07-20
WO2000028031A3 (en) 2000-11-23
CA2350776A1 (en) 2000-05-18
US7226769B2 (en) 2007-06-05
US7048923B2 (en) 2006-05-23
US20030166198A1 (en) 2003-09-04

Similar Documents

Publication Publication Date Title
ATE351905T1 (de) Mitogene regulatoren
Chongdar et al. Unique spectroscopic properties of the H-cluster in a putative sensory [FeFe] hydrogenase
GEP20022681B (en) Protein KFG, Antibodies, Pharmaceutical Composition, Their Use, recombinant DNA, Cell, Method for Discoveries and Production of Proteins, Method for Stimulation of Epithelial Cells Growth
DE69837537D1 (de) Methoden zur messung zellulärer vermehrungs- und abbauraten in vitro und in vivo
EP1244808A4 (de) Verfahren zum screenen von mehrfach transformierten zellen unter verwendung bicistronischer expression von fluoreszenzproteinen
Valkova-Valchanova et al. Isolation and Characterization of a Two-Subunit Cytochrome b− c 1 Subcomplex from Rhodobacter capsulatus and Reconstitution of Its Ubihydroquinone Oxidation (Qo) Site with Purified Fe-S Protein Subunit
NO905556L (no) Flerkomponentmembran og anvendelse av denne.
TR199900624T2 (xx) Proteinlerin y�ksek seviyede ekspresyonu.
ATE400587T1 (de) Gegen das prostata-stammzellantigen (psca) gerichtete antikörper und deren verwendung
DE69942459D1 (de) Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung
Finazzi et al. In vivo characterization of the electrochemical proton gradient generated in darkness in green algae and its kinetic effects on cytochrome b 6 f turnover
TR199701462T1 (xx) DNA Dizisi ve bununla kodlanm�� meme'ye �zel g���s kanseri proteini.
DE69822206D1 (de) Erkenntnisse der genomforschung für die suche nach neuartigen wirkstoffen
DE60024659D1 (de) Vektoren und verfahren für rekombinante proteinexpression
ATE304595T1 (de) Lichtproduzierender biosensor
WO2003027634A3 (en) Identification of modulatory molecules using inducible promoters
WO2002081703A3 (en) Mitogenic oxygenase regulators
NO854448L (no) Sv40 ekspresjonsvektor inneholdende hbxag som en ekspresjonsmarkoer.
PT1025245E (pt) Criacao rapida de linhas celulares estaveis de mamifero produzindo elevados iiveis de proteinas recombinantes
Lin et al. Purification and characterization of mouse kidney beta-glucuronidase.
TR200000140T2 (tr) Endojenik gen etkinliği ile insan proteini üretimi için insan hücre sıralarının belirlenmesi
SE9801148D0 (sv) New receptors
Zhang et al. Electrochemical analysis of immobilised chemical and genetic biotinylated alkaline phosphatase
EP1403365A4 (de) Polypeptid-destabiliserendes protein in zellen unter aeroben bedingungen und dieses codierende dna
WO2004007689A3 (en) Regulatory protein for nox enzymes

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties