ATE353903T1 - Kristalline cefdinirsalze - Google Patents

Kristalline cefdinirsalze

Info

Publication number: ATE353903T1
Authority: AT; Austria
Prior art keywords: salts; crystalline; cefdine; cefdinir; formula
Prior art date: 2002-12-20

Application number

AT03789109T

Other languages

English (en)

Inventor

Giovanni Pozzi

Gomez Patricio Martin

Marco Alpegiani

Walter Cabri

Original Assignee

Antibioticos Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-20

Filing date

2003-12-01

Publication date

2007-03-15

2003-12-01 Application filed by Antibioticos Spa filed Critical Antibioticos Spa

2007-03-15 Application granted granted Critical

2007-03-15 Publication of ATE353903T1 publication Critical patent/ATE353903T1/de

Links

150000003839 salts Chemical class 0.000 title abstract 3
RTXOFQZKPXMALH-GHXIOONMSA-N cefdinir Chemical compound S1C(N)=NC(C(=N\O)\C(=O)N[C@@H]2C(N3C(=C(C=C)CS[C@@H]32)C(O)=O)=O)=C1 RTXOFQZKPXMALH-GHXIOONMSA-N 0.000 abstract 4
229960003719 cefdinir Drugs 0.000 abstract 4
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
238000002360 preparation method Methods 0.000 abstract 2
229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT03789109T 2002-12-20 2003-12-01 Kristalline cefdinirsalze ATE353903T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT002724A ITMI20022724A1 (it)	2002-12-20	2002-12-20	Sali cristallini del cefdinir.

Publications (1)

Publication Number	Publication Date
ATE353903T1 true ATE353903T1 (de)	2007-03-15

Family

ID=32676853

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03789109T ATE353903T1 (de)	2002-12-20	2003-12-01	Kristalline cefdinirsalze

Country Status (12)

Country	Link
US (1)	US7173126B2 (de)
EP (1)	EP1572699B1 (de)
JP (1)	JP2006511561A (de)
AT (1)	ATE353903T1 (de)
AU (1)	AU2003293746A1 (de)
DE (1)	DE60311869T2 (de)
DK (1)	DK1572699T3 (de)
ES (1)	ES2281685T3 (de)
IT (1)	ITMI20022724A1 (de)
PT (1)	PT1572699E (de)
SI (1)	SI1572699T1 (de)
WO (1)	WO2004056835A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100451672B1 (ko) *	2001-06-05	2004-10-08	한미약품 주식회사	결정성 세프디니르 산부가염, 이의 제조방법 및 이를이용한 세프디니르의 제조방법
ITMI20020913A0 (it) *	2002-04-29	2002-04-29	Acs Dobfar Spa	Nuova forma cristallina del cefdinir
AU2003255424A1 (en)	2002-08-13	2004-03-03	Sandoz Ag	A cefdinir intermediate
ITMI20022076A1 (it) *	2002-10-01	2004-04-02	Antibioticos Spa	Sali di intermedi del cefdinir.
US7244842B2 (en) *	2002-11-15	2007-07-17	Orchid Chemicals & Pharmaceuticals Ltd.	Amorphous hydrate of a cephalosporin antibiotic
MXPA05010205A (es) *	2003-03-24	2005-11-08	Acs Dobfar Spa	Nuevo cristal del acido 7-[2-(2- aminotiazol- 4-il)-2- hidroxiiminoacetamido] -3-vinil-3- cefem-4 -carboxilico (isomero syn) y metodo para la preparacion del mismo.
WO2004104010A1 (en) *	2003-05-20	2004-12-02	Ranbaxy Laboratories Limited	Crystalline form of cefdinir
US20050209211A1 (en) *	2004-03-16	2005-09-22	Devalina Law	Trihemihydrate, anhydrate and novel hydrate forms of Cefdinir
US20060069079A1 (en) *	2004-09-27	2006-03-30	Sever Nancy E	Stable amorphous cefdinir
US20050245738A1 (en) *	2004-05-03	2005-11-03	Lupin Ltd	Stable bioavailable crystalline form or cefdinir and a process for the preparation thereof
WO2006018807A1 (en) *	2004-08-16	2006-02-23	Ranbaxy Laboratories Limited	Crystalline forms of cefdinir
MX2007006018A (es) *	2004-11-30	2007-06-07	Astellas Pharma Inc	Suspension farmaceutica oral novedosa de cristal de cefdinir.
WO2006117794A1 (en) *	2005-05-02	2006-11-09	Hetero Drugs Limited	A novel crystalline form of cefdinir
WO2006134607A1 (en) *	2005-06-15	2006-12-21	Hetero Drugs Limited	Cefdinir process
JP2008526782A (ja) *	2005-10-31	2008-07-24	テバファーマシューティカルインダストリーズリミティド	セフジニルセシウム塩結晶
US20070128268A1 (en) *	2005-12-07	2007-06-07	Herwig Jennewein	Pharmaceutical compositions comprising an antibiotic
CN101481383B (zh)	2008-12-31	2012-01-11	杭州奥默医药技术有限公司	头孢地尼酸式复盐化合物及制备方法
CN103012433B (zh) *	2012-12-13	2015-06-24	珠海保税区丽珠合成制药有限公司	头孢地尼晶型b的制备方法
CN103319503A (zh) *	2013-06-09	2013-09-25	四川方向药业有限责任公司	一种头孢地尼的制备方法
CN111635419B (zh) *	2020-07-13	2022-05-24	广药白云山化学制药(珠海)有限公司	一种头孢地尼精制母液的处理方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3757014A (en)	1971-05-07	1973-09-04	Bristol Myers Co	Ts 1,3,4 - oxadiazol-2-yl)thiomethyl)-3-cephem-4-carboxylic acid and sal7-(d-(alpha-amino-alpha-pheyle-acetamido)) - 3-(s-(5-hydroxymethyl -
ZA885709B (en) *	1987-08-19	1989-04-26	Fujisawa Pharmaceutical Co	Novel crystalline 7-(2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4-carboxylic acid(syn isomer)
JPH0674276B2 (ja) *	1987-08-19	1994-09-21	藤沢薬品工業株式会社	７−［２−（２−アミノチアゾール−４−イル）−２−ヒドロキシイミノアセトアミド−３−ビニル−３−セフェム−４−カルボン酸（シン異性体）の新規結晶
WO1992007840A1 (fr) *	1990-11-02	1992-05-14	Taisho Pharmaceutical Co., Ltd.	Derive de thioester de thiazole
AT405283B (de) *	1997-04-04	1999-06-25	Biochemie Gmbh	Neues kristallines 7-(z)-(2-(2-aminothiazol-4-yl) -2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4- carbonsäure dicyclohexylammoniumsalz und verfahren zu dessen herstellung
IT1317735B1 (it) *	2000-01-26	2003-07-15	Nicox Sa	Sali di agenti antimicrobici.
JP4544692B2 (ja) *	2000-04-13	2010-09-15	大塚化学株式会社	３−ビニル−セフェム化合物の製造方法
KR100451672B1 (ko) *	2001-06-05	2004-10-08	한미약품 주식회사	결정성 세프디니르 산부가염, 이의 제조방법 및 이를이용한 세프디니르의 제조방법
US20060040915A1 (en) *	2002-04-26	2006-02-23	Yatendra Kumar	Process for the preparation of cefdinir
AU2003255424A1 (en) *	2002-08-13	2004-03-03	Sandoz Ag	A cefdinir intermediate
GB0416379D0 (en) *	2004-07-22	2004-08-25	Sandoz Ag	Organic compounds

2002
- 2002-12-20 IT IT002724A patent/ITMI20022724A1/it unknown
2003
- 2003-12-01 JP JP2004561199A patent/JP2006511561A/ja active Pending
- 2003-12-01 AT AT03789109T patent/ATE353903T1/de active
- 2003-12-01 ES ES03789109T patent/ES2281685T3/es not_active Expired - Lifetime
- 2003-12-01 DE DE60311869T patent/DE60311869T2/de not_active Expired - Lifetime
- 2003-12-01 EP EP03789109A patent/EP1572699B1/de not_active Expired - Lifetime
- 2003-12-01 DK DK03789109T patent/DK1572699T3/da active
- 2003-12-01 PT PT03789109T patent/PT1572699E/pt unknown
- 2003-12-01 SI SI200330704T patent/SI1572699T1/sl unknown
- 2003-12-01 AU AU2003293746A patent/AU2003293746A1/en not_active Abandoned
- 2003-12-01 US US10/539,122 patent/US7173126B2/en not_active Expired - Fee Related
- 2003-12-01 WO PCT/EP2003/013524 patent/WO2004056835A1/en not_active Ceased

Also Published As

Publication number	Publication date
SI1572699T1 (sl)	2007-06-30
DK1572699T3 (da)	2007-06-11
AU2003293746A1 (en)	2004-07-14
DE60311869D1 (de)	2007-03-29
EP1572699B1 (de)	2007-02-14
US20060074236A1 (en)	2006-04-06
WO2004056835A1 (en)	2004-07-08
US7173126B2 (en)	2007-02-06
ITMI20022724A1 (it)	2004-06-21
EP1572699A1 (de)	2005-09-14
ES2281685T3 (es)	2007-10-01
PT1572699E (pt)	2007-05-31
DE60311869T2 (de)	2007-09-20
JP2006511561A (ja)	2006-04-06

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