ATE353903T1 - Kristalline cefdinirsalze - Google Patents
Kristalline cefdinirsalzeInfo
- Publication number
- ATE353903T1 ATE353903T1 AT03789109T AT03789109T ATE353903T1 AT E353903 T1 ATE353903 T1 AT E353903T1 AT 03789109 T AT03789109 T AT 03789109T AT 03789109 T AT03789109 T AT 03789109T AT E353903 T1 ATE353903 T1 AT E353903T1
- Authority
- AT
- Austria
- Prior art keywords
- salts
- crystalline
- cefdine
- cefdinir
- formula
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 3
- RTXOFQZKPXMALH-GHXIOONMSA-N cefdinir Chemical compound S1C(N)=NC(C(=N\O)\C(=O)N[C@@H]2C(N3C(=C(C=C)CS[C@@H]32)C(O)=O)=O)=C1 RTXOFQZKPXMALH-GHXIOONMSA-N 0.000 abstract 4
- 229960003719 cefdinir Drugs 0.000 abstract 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT002724A ITMI20022724A1 (it) | 2002-12-20 | 2002-12-20 | Sali cristallini del cefdinir. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE353903T1 true ATE353903T1 (de) | 2007-03-15 |
Family
ID=32676853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03789109T ATE353903T1 (de) | 2002-12-20 | 2003-12-01 | Kristalline cefdinirsalze |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7173126B2 (de) |
| EP (1) | EP1572699B1 (de) |
| JP (1) | JP2006511561A (de) |
| AT (1) | ATE353903T1 (de) |
| AU (1) | AU2003293746A1 (de) |
| DE (1) | DE60311869T2 (de) |
| DK (1) | DK1572699T3 (de) |
| ES (1) | ES2281685T3 (de) |
| IT (1) | ITMI20022724A1 (de) |
| PT (1) | PT1572699E (de) |
| SI (1) | SI1572699T1 (de) |
| WO (1) | WO2004056835A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100451672B1 (ko) * | 2001-06-05 | 2004-10-08 | 한미약품 주식회사 | 결정성 세프디니르 산부가염, 이의 제조방법 및 이를이용한 세프디니르의 제조방법 |
| ITMI20020913A0 (it) * | 2002-04-29 | 2002-04-29 | Acs Dobfar Spa | Nuova forma cristallina del cefdinir |
| ATE501154T1 (de) * | 2002-08-13 | 2011-03-15 | Sandoz Ag | Ein cefdinir-zwischenprodukt |
| ITMI20022076A1 (it) * | 2002-10-01 | 2004-04-02 | Antibioticos Spa | Sali di intermedi del cefdinir. |
| WO2004046154A1 (en) * | 2002-11-15 | 2004-06-03 | Orchid Chemicals & Pharmaceuticals Ltd | Novel amorphous hydrate of a cephalosporin antibiotic |
| EP1609793A4 (de) * | 2003-03-24 | 2008-06-25 | Sandoz Ag | Neuer kristall von 7-¬2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido-3-vinyl-3-cephem-4-carbonsäure(syn-isomer) und verfahren zu dessen herstellung |
| WO2004104010A1 (en) * | 2003-05-20 | 2004-12-02 | Ranbaxy Laboratories Limited | Crystalline form of cefdinir |
| US20050209211A1 (en) * | 2004-03-16 | 2005-09-22 | Devalina Law | Trihemihydrate, anhydrate and novel hydrate forms of Cefdinir |
| US20060069079A1 (en) * | 2004-09-27 | 2006-03-30 | Sever Nancy E | Stable amorphous cefdinir |
| US20050245738A1 (en) * | 2004-05-03 | 2005-11-03 | Lupin Ltd | Stable bioavailable crystalline form or cefdinir and a process for the preparation thereof |
| WO2006018807A1 (en) * | 2004-08-16 | 2006-02-23 | Ranbaxy Laboratories Limited | Crystalline forms of cefdinir |
| WO2006059753A1 (en) * | 2004-11-30 | 2006-06-08 | Astellas Pharma Inc. | Novel oral pharmaceutical suspension of cefdinir crystal |
| WO2006117794A1 (en) * | 2005-05-02 | 2006-11-09 | Hetero Drugs Limited | A novel crystalline form of cefdinir |
| US20080287673A1 (en) * | 2005-06-15 | 2008-11-20 | Parthasaradhi Reddy Bandk | Cefdinir process |
| KR100912214B1 (ko) * | 2005-10-31 | 2009-08-14 | 테바 파마슈티컬 인더스트리즈 리미티드 | 세프디니르 세슘 염의 결정형 |
| US20070128268A1 (en) * | 2005-12-07 | 2007-06-07 | Herwig Jennewein | Pharmaceutical compositions comprising an antibiotic |
| CN101481383B (zh) | 2008-12-31 | 2012-01-11 | 杭州奥默医药技术有限公司 | 头孢地尼酸式复盐化合物及制备方法 |
| CN103012433B (zh) * | 2012-12-13 | 2015-06-24 | 珠海保税区丽珠合成制药有限公司 | 头孢地尼晶型b的制备方法 |
| CN103319503A (zh) * | 2013-06-09 | 2013-09-25 | 四川方向药业有限责任公司 | 一种头孢地尼的制备方法 |
| CN111635419B (zh) * | 2020-07-13 | 2022-05-24 | 广药白云山化学制药(珠海)有限公司 | 一种头孢地尼精制母液的处理方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3757014A (en) | 1971-05-07 | 1973-09-04 | Bristol Myers Co | Ts 1,3,4 - oxadiazol-2-yl)thiomethyl)-3-cephem-4-carboxylic acid and sal7-(d-(alpha-amino-alpha-pheyle-acetamido)) - 3-(s-(5-hydroxymethyl - |
| ZA885709B (en) * | 1987-08-19 | 1989-04-26 | Fujisawa Pharmaceutical Co | Novel crystalline 7-(2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4-carboxylic acid(syn isomer) |
| JPH0674276B2 (ja) * | 1987-08-19 | 1994-09-21 | 藤沢薬品工業株式会社 | ７−［２−（２−アミノチアゾール−４−イル）−２−ヒドロキシイミノアセトアミド−３−ビニル−３−セフェム−４−カルボン酸（シン異性体）の新規結晶 |
| WO1992007840A1 (fr) * | 1990-11-02 | 1992-05-14 | Taisho Pharmaceutical Co., Ltd. | Derive de thioester de thiazole |
| AT405283B (de) * | 1997-04-04 | 1999-06-25 | Biochemie Gmbh | Neues kristallines 7-(z)-(2-(2-aminothiazol-4-yl) -2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4- carbonsäure dicyclohexylammoniumsalz und verfahren zu dessen herstellung |
| IT1317735B1 (it) * | 2000-01-26 | 2003-07-15 | Nicox Sa | Sali di agenti antimicrobici. |
| JP4544692B2 (ja) * | 2000-04-13 | 2010-09-15 | 大塚化学株式会社 | ３−ビニル−セフェム化合物の製造方法 |
| KR100451672B1 (ko) * | 2001-06-05 | 2004-10-08 | 한미약품 주식회사 | 결정성 세프디니르 산부가염, 이의 제조방법 및 이를이용한 세프디니르의 제조방법 |
| CN1628118A (zh) * | 2002-04-26 | 2005-06-15 | 兰贝克赛实验室有限公司 | 制备头孢地尼的方法 |
| ATE501154T1 (de) * | 2002-08-13 | 2011-03-15 | Sandoz Ag | Ein cefdinir-zwischenprodukt |
| GB0416379D0 (en) * | 2004-07-22 | 2004-08-25 | Sandoz Ag | Organic compounds |
-
2002
- 2002-12-20 IT IT002724A patent/ITMI20022724A1/it unknown
-
2003
- 2003-12-01 DK DK03789109T patent/DK1572699T3/da active
- 2003-12-01 WO PCT/EP2003/013524 patent/WO2004056835A1/en not_active Ceased
- 2003-12-01 EP EP03789109A patent/EP1572699B1/de not_active Expired - Lifetime
- 2003-12-01 PT PT03789109T patent/PT1572699E/pt unknown
- 2003-12-01 JP JP2004561199A patent/JP2006511561A/ja active Pending
- 2003-12-01 ES ES03789109T patent/ES2281685T3/es not_active Expired - Lifetime
- 2003-12-01 DE DE60311869T patent/DE60311869T2/de not_active Expired - Lifetime
- 2003-12-01 SI SI200330704T patent/SI1572699T1/sl unknown
- 2003-12-01 US US10/539,122 patent/US7173126B2/en not_active Expired - Fee Related
- 2003-12-01 AU AU2003293746A patent/AU2003293746A1/en not_active Abandoned
- 2003-12-01 AT AT03789109T patent/ATE353903T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| US7173126B2 (en) | 2007-02-06 |
| EP1572699B1 (de) | 2007-02-14 |
| ES2281685T3 (es) | 2007-10-01 |
| DE60311869D1 (de) | 2007-03-29 |
| JP2006511561A (ja) | 2006-04-06 |
| DK1572699T3 (da) | 2007-06-11 |
| US20060074236A1 (en) | 2006-04-06 |
| ITMI20022724A1 (it) | 2004-06-21 |
| PT1572699E (pt) | 2007-05-31 |
| DE60311869T2 (de) | 2007-09-20 |
| WO2004056835A1 (en) | 2004-07-08 |
| EP1572699A1 (de) | 2005-09-14 |
| AU2003293746A1 (en) | 2004-07-14 |
| SI1572699T1 (sl) | 2007-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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