ATE356872T1 - Verwendung von protein maba (fabg1) aus mycobacterium tuberculosis zur herstellung und nachweis von antibiotika - Google Patents
Verwendung von protein maba (fabg1) aus mycobacterium tuberculosis zur herstellung und nachweis von antibiotikaInfo
- Publication number
- ATE356872T1 ATE356872T1 AT03740540T AT03740540T ATE356872T1 AT E356872 T1 ATE356872 T1 AT E356872T1 AT 03740540 T AT03740540 T AT 03740540T AT 03740540 T AT03740540 T AT 03740540T AT E356872 T1 ATE356872 T1 AT E356872T1
- Authority
- AT
- Austria
- Prior art keywords
- proteins
- maba
- fabg1
- protein
- antibiotics
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 9
- 108090000623 proteins and genes Proteins 0.000 title abstract 9
- 241000989747 Maba Species 0.000 title abstract 5
- XFDUHJPVQKIXHO-UHFFFAOYSA-N 3-aminobenzoic acid Chemical compound NC1=CC=CC(C(O)=O)=C1 XFDUHJPVQKIXHO-UHFFFAOYSA-N 0.000 title 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 2
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- 230000035772 mutation Effects 0.000 abstract 2
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C30—CRYSTAL GROWTH
- C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
- C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Metallurgy (AREA)
- Materials Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0204018A FR2837836B1 (fr) | 2002-03-29 | 2002-03-29 | UTILISATION DE LA PROTEINE Maba (FABG1) DE MYCOBACTERIUM TUBERCULOSIS POUR LA CONCEPTION ET LE CRIBLAGE D'ANTIBIOTIQUES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE356872T1 true ATE356872T1 (de) | 2007-04-15 |
Family
ID=27839347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03740540T ATE356872T1 (de) | 2002-03-29 | 2003-03-28 | Verwendung von protein maba (fabg1) aus mycobacterium tuberculosis zur herstellung und nachweis von antibiotika |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20060035294A1 (de) |
| EP (1) | EP1490491B1 (de) |
| AT (1) | ATE356872T1 (de) |
| AU (1) | AU2003258723A1 (de) |
| DE (1) | DE60312497T2 (de) |
| ES (1) | ES2283790T3 (de) |
| FR (1) | FR2837836B1 (de) |
| WO (1) | WO2003082911A2 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100113291A1 (en) * | 2006-03-23 | 2010-05-06 | Centre National De La Recherche Scientifique | Complexes of nadp with the protein maba of mycobacterium tuberculosis or with mutants thereof, and their uses for designing and screening antibiotics |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09501823A (ja) * | 1993-05-13 | 1997-02-25 | アール．，ジュニア ヤコブス，ウィリアム | ｉｎｈＡ遺伝子を用いるミコバクテリア感染の検出および処置のための方法および組成物 |
| AU6949694A (en) * | 1993-05-13 | 1994-12-12 | Agresearch Limited | Use of genes of m. tuberculosis, m. bovis and m. smegmatis which confer isoniazid resistance |
-
2002
- 2002-03-29 FR FR0204018A patent/FR2837836B1/fr not_active Expired - Fee Related
-
2003
- 2003-03-28 ES ES03740540T patent/ES2283790T3/es not_active Expired - Lifetime
- 2003-03-28 AU AU2003258723A patent/AU2003258723A1/en not_active Abandoned
- 2003-03-28 WO PCT/FR2003/000990 patent/WO2003082911A2/fr not_active Ceased
- 2003-03-28 EP EP03740540A patent/EP1490491B1/de not_active Expired - Lifetime
- 2003-03-28 DE DE60312497T patent/DE60312497T2/de not_active Expired - Lifetime
- 2003-03-28 AT AT03740540T patent/ATE356872T1/de not_active IP Right Cessation
- 2003-03-28 US US10/503,939 patent/US20060035294A1/en not_active Abandoned
-
2009
- 2009-04-14 US US12/423,586 patent/US20100240084A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| FR2837836B1 (fr) | 2005-04-22 |
| DE60312497D1 (de) | 2007-04-26 |
| EP1490491A2 (de) | 2004-12-29 |
| AU2003258723A1 (en) | 2003-10-13 |
| AU2003258723A8 (en) | 2003-10-13 |
| DE60312497T2 (de) | 2007-09-20 |
| US20100240084A1 (en) | 2010-09-23 |
| EP1490491B1 (de) | 2007-03-14 |
| ES2283790T3 (es) | 2007-11-01 |
| FR2837836A1 (fr) | 2003-10-03 |
| US20060035294A1 (en) | 2006-02-16 |
| WO2003082911A3 (fr) | 2004-04-01 |
| WO2003082911A2 (fr) | 2003-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |