ATE481983T1 - Frpb proteinmutante und verfahren zur erneuten faltung - Google Patents

Frpb proteinmutante und verfahren zur erneuten faltung

Info

Publication number
ATE481983T1
ATE481983T1 AT03779785T AT03779785T ATE481983T1 AT E481983 T1 ATE481983 T1 AT E481983T1 AT 03779785 T AT03779785 T AT 03779785T AT 03779785 T AT03779785 T AT 03779785T AT E481983 T1 ATE481983 T1 AT E481983T1
Authority
AT
Austria
Prior art keywords
frpb protein
protein mutant
refolding method
frpb
refolding
Prior art date
Application number
AT03779785T
Other languages
English (en)
Inventor
Ralph Biemans
Philippe Denoel
Christiane Feron
Carine Goraj
Jeroen Kortekaas
Jan Poolman
Jan Tommassen
Vincent Weynants
Original Assignee
Glaxosmithkline Biolog Sa
Univ Utrecht
Technology Foundation Stichtin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa, Univ Utrecht, Technology Foundation Stichtin filed Critical Glaxosmithkline Biolog Sa
Application granted granted Critical
Publication of ATE481983T1 publication Critical patent/ATE481983T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/104Pseudomonadales, e.g. Pseudomonas
    • A61K39/1045Moraxella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT03779785T 2002-08-30 2003-08-28 Frpb proteinmutante und verfahren zur erneuten faltung ATE481983T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0220199.4A GB0220199D0 (en) 2002-08-30 2002-08-30 Mutant protein and refolding method
PCT/EP2003/009634 WO2004020463A2 (en) 2002-08-30 2003-08-28 Mutant protein and refolding method

Publications (1)

Publication Number Publication Date
ATE481983T1 true ATE481983T1 (de) 2010-10-15

Family

ID=9943242

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03779785T ATE481983T1 (de) 2002-08-30 2003-08-28 Frpb proteinmutante und verfahren zur erneuten faltung

Country Status (10)

Country Link
US (1) US20060141563A1 (de)
EP (1) EP1572729B1 (de)
JP (1) JP2006516183A (de)
AT (1) ATE481983T1 (de)
AU (1) AU2003287945A1 (de)
CA (1) CA2495086A1 (de)
DE (1) DE60334316D1 (de)
ES (1) ES2351598T3 (de)
GB (1) GB0220199D0 (de)
WO (1) WO2004020463A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2414667A (en) 2004-06-03 2005-12-07 Isis Innovation Vaccine compositions of N. meningitidis PorA and FetA antigens
US9486515B2 (en) 2005-06-27 2016-11-08 Glaxosmithkline Biologicals S.A. Immunogenic composition
EP2032161B1 (de) * 2006-06-12 2012-07-11 GlaxoSmithKline Biologicals S.A. L3v los impfstoffe
WO2010074126A1 (ja) * 2008-12-25 2010-07-01 財団法人化学及血清療法研究所 組換え鶏伝染性コリーザワクチン及びその製造方法
ES2759484T3 (es) * 2010-09-10 2020-05-11 Glaxosmithkline Biologicals Sa Meningococo que sobreexpresa NadA y/o NHBA y vesículas de la membrana externa derivadas del mismo
WO2012041899A1 (en) * 2010-09-28 2012-04-05 Xbrane Bioscience Ab Fusion protein for secretory protein expression

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265567B1 (en) * 1995-04-07 2001-07-24 University Of North Carolina At Chapel Hill Isolated FrpB nucleic acid molecule
EP0943690B1 (de) * 1995-12-21 2006-11-29 Ajinomoto Co., Inc. Verfahren zur rückfaltung von menschlichem activin a
EP1252182B1 (de) * 2000-01-25 2012-06-20 The University Of Queensland KONSERVIERTE REGIONEN DES NEISSERIA MENINGITIDIS OBERFLÄCHENANTIGENS NhhA ENTHALTENDE PROTEINE

Also Published As

Publication number Publication date
JP2006516183A (ja) 2006-06-29
EP1572729A2 (de) 2005-09-14
EP1572729B1 (de) 2010-09-22
AU2003287945A8 (en) 2004-03-19
GB0220199D0 (en) 2002-10-09
ES2351598T3 (es) 2011-02-08
AU2003287945A1 (en) 2004-03-19
US20060141563A1 (en) 2006-06-29
WO2004020463A3 (en) 2005-08-18
WO2004020463A2 (en) 2004-03-11
CA2495086A1 (en) 2004-03-11
DE60334316D1 (de) 2010-11-04

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties