ATE357218T1 - Micropartikel - Google Patents

Micropartikel

Info

Publication number
ATE357218T1
ATE357218T1 AT02075905T AT02075905T ATE357218T1 AT E357218 T1 ATE357218 T1 AT E357218T1 AT 02075905 T AT02075905 T AT 02075905T AT 02075905 T AT02075905 T AT 02075905T AT E357218 T1 ATE357218 T1 AT E357218T1
Authority
AT
Austria
Prior art keywords
microparticles
organic solvent
total weight
active agent
less
Prior art date
Application number
AT02075905T
Other languages
English (en)
Inventor
Michael E Rickey
J Michael Ramstack
Danny H Lewis
Jean Louis Mesens
Original Assignee
Alkermes Inc
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24582704&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE357218(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alkermes Inc, Janssen Pharmaceutica Nv filed Critical Alkermes Inc
Application granted granted Critical
Publication of ATE357218T1 publication Critical patent/ATE357218T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT02075905T 1996-05-07 1997-05-06 Micropartikel ATE357218T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64391996A 1996-05-07 1996-05-07

Publications (1)

Publication Number Publication Date
ATE357218T1 true ATE357218T1 (de) 2007-04-15

Family

ID=24582704

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02075905T ATE357218T1 (de) 1996-05-07 1997-05-06 Micropartikel
AT97923063T ATE223206T1 (de) 1996-05-07 1997-05-06 Verfahren zur herstellung von mikropartikeln

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT97923063T ATE223206T1 (de) 1996-05-07 1997-05-06 Verfahren zur herstellung von mikropartikeln

Country Status (11)

Country Link
EP (1) EP1210942B1 (de)
AT (2) ATE357218T1 (de)
CY (1) CY2318B1 (de)
DE (2) DE69737515T2 (de)
DK (2) DK1210942T3 (de)
ES (2) ES2183172T3 (de)
HK (1) HK1047539B (de)
MY (1) MY118174A (de)
PT (2) PT1210942E (de)
SI (2) SI0904063T1 (de)
TR (1) TR199802258T2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7193084B2 (en) 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
US6884436B2 (en) 2000-12-22 2005-04-26 Baxter International Inc. Method for preparing submicron particle suspensions
US6977085B2 (en) 2000-12-22 2005-12-20 Baxter International Inc. Method for preparing submicron suspensions with polymorph control
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US6607784B2 (en) 2000-12-22 2003-08-19 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US6951656B2 (en) 2000-12-22 2005-10-04 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
AU2002337692B2 (en) 2001-09-26 2007-09-13 Baxter International Inc. Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
US7112340B2 (en) 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
WO2008143992A2 (en) 2007-05-18 2008-11-27 Durect Corporation Improved depot formulations
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
BRPI0811319A2 (pt) 2007-05-25 2015-02-10 Tolmar Therapeutics Inc Composição fluida, método de formação de uma composição fluida, implante biodegrádavel formado in situ, método de formação de um implante biodegradável in situ, kit, implante e método de trataento
US20140308352A1 (en) 2013-03-11 2014-10-16 Zogenix Inc. Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material
EP2986278A1 (de) 2013-03-11 2016-02-24 DURECT Corporation Injizierbare zusammensetzung mit gesteuerter freisetzung mit einem hochviskosen flüssigen träger
CN104226191B (zh) * 2014-09-01 2017-04-19 南京理工大学 乙基纤维素多孔颗粒的常温制备方法
EP3784705A4 (de) * 2018-04-23 2022-03-02 Graybug Vision, Inc. Verbesserte kontinuierliche mikropartikelherstellung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
US5478564A (en) * 1990-02-22 1995-12-26 Teva Pharmaceutical Industries, Ltd. Preparation of microparticles for controlled release of water-soluble substances
FR2693905B1 (fr) * 1992-07-27 1994-09-02 Rhone Merieux Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
ATE188375T1 (de) * 1992-11-17 2000-01-15 Yoshitomi Pharmaceutical Ein antipsychotikum enthaltende mikrokugel zur verzögerten freisetzung und verfahren für ihre herstellung
DE69415684T2 (de) * 1993-10-22 1999-06-10 Genentech Inc., San Francisco, Calif. Verfahren zur herstellung von mikrospharen mit einer wirbelschichtstufe
ATE288270T1 (de) * 1993-11-19 2005-02-15 Janssen Pharmaceutica Nv Mikroverkapselte 1,2-benzazole
EP2283821A1 (de) * 1993-11-19 2011-02-16 Alkermes, Inc. Herstellung biodegradierbarer Mikroteilchen, die ein biologisch aktives Mittel enthalten

Also Published As

Publication number Publication date
HK1047539A1 (en) 2003-02-28
HK1047539B (en) 2007-08-24
DE69715191D1 (de) 2002-10-10
TR199802258T2 (en) 2001-11-21
DE69715191T2 (de) 2003-04-30
MY118174A (en) 2004-09-30
HK1016884A1 (en) 1999-11-12
SI0904063T1 (en) 2003-02-28
ATE223206T1 (de) 2002-09-15
EP1210942A2 (de) 2002-06-05
CY2318B1 (en) 2003-11-14
SI1210942T1 (sl) 2007-10-31
ES2183172T3 (es) 2003-03-16
EP1210942A3 (de) 2004-05-26
DE69737515D1 (de) 2007-05-03
DK1210942T3 (da) 2007-07-23
PT1210942E (pt) 2007-06-26
EP1210942B1 (de) 2007-03-21
DE69737515T2 (de) 2007-12-06
PT904063E (pt) 2003-01-31
DK0904063T3 (da) 2002-12-16
ES2284776T3 (es) 2007-11-16

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