DK0904063T3 - Fremgangsmåde til fremstilling af mikropartikler - Google Patents

Fremgangsmåde til fremstilling af mikropartikler

Info

Publication number
DK0904063T3
DK0904063T3 DK97923063T DK97923063T DK0904063T3 DK 0904063 T3 DK0904063 T3 DK 0904063T3 DK 97923063 T DK97923063 T DK 97923063T DK 97923063 T DK97923063 T DK 97923063T DK 0904063 T3 DK0904063 T3 DK 0904063T3
Authority
DK
Denmark
Prior art keywords
microparticles
preparation
organic solvent
total weight
active agent
Prior art date
Application number
DK97923063T
Other languages
English (en)
Inventor
Michael E Rickey
J Michael Ramstack
Danny H Lewis
Jean Louis Mesens
Original Assignee
Alkermes Inc
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24582704&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0904063(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alkermes Inc, Janssen Pharmaceutica Nv filed Critical Alkermes Inc
Priority claimed from PCT/EP1997/002431 external-priority patent/WO1997041837A2/en
Application granted granted Critical
Publication of DK0904063T3 publication Critical patent/DK0904063T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DK97923063T 1996-05-07 1997-05-06 Fremgangsmåde til fremstilling af mikropartikler DK0904063T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64391996A 1996-05-07 1996-05-07
PCT/EP1997/002431 WO1997041837A2 (en) 1996-05-07 1997-05-06 Microparticles

Publications (1)

Publication Number Publication Date
DK0904063T3 true DK0904063T3 (da) 2002-12-16

Family

ID=24582704

Family Applications (2)

Application Number Title Priority Date Filing Date
DK97923063T DK0904063T3 (da) 1996-05-07 1997-05-06 Fremgangsmåde til fremstilling af mikropartikler
DK02075905T DK1210942T3 (da) 1996-05-07 1997-05-06 Mikropartikler

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK02075905T DK1210942T3 (da) 1996-05-07 1997-05-06 Mikropartikler

Country Status (11)

Country Link
EP (1) EP1210942B1 (da)
AT (2) ATE357218T1 (da)
CY (1) CY2318B1 (da)
DE (2) DE69715191T2 (da)
DK (2) DK0904063T3 (da)
ES (2) ES2183172T3 (da)
HK (1) HK1047539B (da)
MY (1) MY118174A (da)
PT (2) PT904063E (da)
SI (2) SI0904063T1 (da)
TR (1) TR199802258T2 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7193084B2 (en) 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
US6884436B2 (en) 2000-12-22 2005-04-26 Baxter International Inc. Method for preparing submicron particle suspensions
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US7037528B2 (en) 2000-12-22 2006-05-02 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US6977085B2 (en) 2000-12-22 2005-12-20 Baxter International Inc. Method for preparing submicron suspensions with polymorph control
US6951656B2 (en) 2000-12-22 2005-10-04 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
BR0212833A (pt) 2001-09-26 2004-10-13 Baxter Int Preparação de nanopartìculas de tamanho submìcron através de dispersão e de remoção de solvente ou de fase lìquida
US7112340B2 (en) 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
EP2167039B1 (en) 2007-05-18 2016-09-28 Durect Corporation Improved depot formulations
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
ES2562878T3 (es) 2007-05-25 2016-03-08 Indivior Uk Limited Formulaciones de liberación sostenida de compuestos de risperidona
EA033537B1 (ru) 2013-03-11 2019-10-31 Durect Corp Инъекционная композиция с контролируемым высвобождением, содержащая жидкий носитель с высокой вязкостью
US20140308352A1 (en) 2013-03-11 2014-10-16 Zogenix Inc. Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material
CN104226191B (zh) * 2014-09-01 2017-04-19 南京理工大学 乙基纤维素多孔颗粒的常温制备方法
WO2019209883A1 (en) * 2018-04-23 2019-10-31 Graybug Vision, Inc. Improved continuous microparticle manufacture

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
US5478564A (en) * 1990-02-22 1995-12-26 Teva Pharmaceutical Industries, Ltd. Preparation of microparticles for controlled release of water-soluble substances
FR2693905B1 (fr) * 1992-07-27 1994-09-02 Rhone Merieux Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
DE69327542T2 (de) * 1992-11-17 2000-07-06 Yoshitomi Pharmaceutical Industries, Ltd. Ein antipsychotikum enthaltende mikrokugel zur verzögerten freisetzung und verfahren für ihre herstellung
EP0724433B1 (en) * 1993-10-22 1998-12-30 Genentech, Inc. Method for preparing microspheres comprising a fluidized bed drying step
CN1074923C (zh) * 1993-11-19 2001-11-21 詹森药业有限公司 微囊密封的3-哌啶基取代的1,2-苯并异唑类和1,2-苯并异噻唑类
EP2283821A1 (en) * 1993-11-19 2011-02-16 Alkermes, Inc. Preparation of biodegradable microparticles containing a biologically active agent

Also Published As

Publication number Publication date
DE69737515D1 (de) 2007-05-03
DE69737515T2 (de) 2007-12-06
EP1210942A2 (en) 2002-06-05
DE69715191T2 (de) 2003-04-30
DE69715191D1 (de) 2002-10-10
SI1210942T1 (sl) 2007-10-31
ES2284776T3 (es) 2007-11-16
PT1210942E (pt) 2007-06-26
PT904063E (pt) 2003-01-31
ATE357218T1 (de) 2007-04-15
CY2318B1 (en) 2003-11-14
HK1047539A1 (en) 2003-02-28
EP1210942A3 (en) 2004-05-26
ES2183172T3 (es) 2003-03-16
HK1047539B (en) 2007-08-24
DK1210942T3 (da) 2007-07-23
EP1210942B1 (en) 2007-03-21
MY118174A (en) 2004-09-30
TR199802258T2 (en) 2001-11-21
HK1016884A1 (en) 1999-11-12
ATE223206T1 (de) 2002-09-15
SI0904063T1 (en) 2003-02-28

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