ATE357447T1 - Inhibitoren des papilloma-virus - Google Patents
Inhibitoren des papilloma-virusInfo
- Publication number
- ATE357447T1 ATE357447T1 AT01271377T AT01271377T ATE357447T1 AT E357447 T1 ATE357447 T1 AT E357447T1 AT 01271377 T AT01271377 T AT 01271377T AT 01271377 T AT01271377 T AT 01271377T AT E357447 T1 ATE357447 T1 AT E357447T1
- Authority
- AT
- Austria
- Prior art keywords
- optionally
- het
- substituted
- heteroatom
- unsaturated
- Prior art date
Links
- 241001631646 Papillomaviridae Species 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 7
- 229920006395 saturated elastomer Polymers 0.000 abstract 5
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical group C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 2
- 239000005977 Ethylene Substances 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 208000009608 Papillomavirus Infections Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical group 0.000 abstract 1
- 150000002118 epoxides Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 208000021145 human papilloma virus infection Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25670600P | 2000-12-18 | 2000-12-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE357447T1 true ATE357447T1 (de) | 2007-04-15 |
Family
ID=22973265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01271377T ATE357447T1 (de) | 2000-12-18 | 2001-12-14 | Inhibitoren des papilloma-virus |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1345943B1 (de) |
| JP (1) | JP4458745B2 (de) |
| AT (1) | ATE357447T1 (de) |
| AU (1) | AU2002218897A1 (de) |
| CA (1) | CA2430909C (de) |
| DE (1) | DE60127451T2 (de) |
| ES (1) | ES2282196T3 (de) |
| HU (1) | HUP0303418A3 (de) |
| IL (1) | IL156191A0 (de) |
| MX (1) | MXPA03005479A (de) |
| NZ (1) | NZ526978A (de) |
| WO (1) | WO2002050082A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7167801B2 (en) * | 2001-07-12 | 2007-01-23 | Boehringer Ingelheim (Canada) Ltd. | Method of identifying potential inhibitors of human papillomavirus protein E2 using x-ray atomic coordinates |
| EP1474690B1 (de) * | 2002-02-07 | 2010-10-13 | Boehringer Ingelheim (Canada) Ltd. | E2-verdrängungs-assay zur identifizierung von hpv-inhibitoren |
| ATE458485T1 (de) * | 2003-07-11 | 2010-03-15 | Proteologics Inc | Ubiquitin-ligase-hemmer und verwandte verfahren |
| WO2011133929A2 (en) * | 2010-04-23 | 2011-10-27 | University Of Rochester | Reducing transmission of sexually transmitted infections |
| CN111606914B (zh) * | 2019-02-22 | 2023-01-17 | 中国科学院昆明植物研究所 | [吡咯并呋喃]-螺环茚酮类化合物及药物组合物和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4106283A1 (de) * | 1991-02-28 | 1992-09-03 | Boehringer Mannheim Gmbh | Verwendung von tricyclischen isoindolinonen als antivirale arzneimittel, sowie neue optisch aktive isoindolinone |
| WO2000017206A1 (en) * | 1998-09-18 | 2000-03-30 | Cubist Pharmaceuticals, Inc. | Tetracyclic heterocycles as antimicrobial agents |
-
2001
- 2001-12-14 HU HU0303418A patent/HUP0303418A3/hu unknown
- 2001-12-14 IL IL15619101A patent/IL156191A0/xx unknown
- 2001-12-14 AT AT01271377T patent/ATE357447T1/de active
- 2001-12-14 NZ NZ526978A patent/NZ526978A/en unknown
- 2001-12-14 DE DE60127451T patent/DE60127451T2/de not_active Expired - Lifetime
- 2001-12-14 ES ES01271377T patent/ES2282196T3/es not_active Expired - Lifetime
- 2001-12-14 WO PCT/CA2001/001800 patent/WO2002050082A2/en not_active Ceased
- 2001-12-14 CA CA2430909A patent/CA2430909C/en not_active Expired - Fee Related
- 2001-12-14 EP EP01271377A patent/EP1345943B1/de not_active Expired - Lifetime
- 2001-12-14 MX MXPA03005479A patent/MXPA03005479A/es unknown
- 2001-12-14 JP JP2002551975A patent/JP4458745B2/ja not_active Expired - Fee Related
- 2001-12-14 AU AU2002218897A patent/AU2002218897A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002050082A3 (en) | 2002-12-19 |
| EP1345943A2 (de) | 2003-09-24 |
| EP1345943B1 (de) | 2007-03-21 |
| DE60127451T2 (de) | 2007-11-29 |
| JP4458745B2 (ja) | 2010-04-28 |
| NZ526978A (en) | 2005-12-23 |
| DE60127451D1 (de) | 2007-05-03 |
| IL156191A0 (en) | 2003-12-23 |
| CA2430909C (en) | 2010-12-14 |
| MXPA03005479A (es) | 2004-05-31 |
| ES2282196T3 (es) | 2007-10-16 |
| CA2430909A1 (en) | 2002-06-27 |
| AU2002218897A1 (en) | 2002-07-01 |
| WO2002050082A2 (en) | 2002-06-27 |
| JP2004515555A (ja) | 2004-05-27 |
| HUP0303418A3 (en) | 2007-05-02 |
| HUP0303418A2 (hu) | 2004-01-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20020541B1 (en) | Pyrrolidine derivatives as cyclic amp-specific phosphodiesterase inhibitors | |
| HRP20031098B1 (en) | Beta-amino tetrahydroimidazo (1,2-a) pyrazines and tetrahydrotrioazolo (4,3-a) pyrazines as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes | |
| EA200100755A1 (ru) | 4-оксо-1,4-дигидро-3-хинолинкарбоксамиды как антивирусные агенты | |
| BR0309447A (pt) | Composto, agente, processos para a preparação dos mesmos, e para o combate do crescimento de plantas indesejadas, e, uso do composto | |
| PE20011055A1 (es) | Compuestos de imidazolidin 2,4-diona sustituida y procedimientos para su preparacion | |
| ATE258552T1 (de) | Oxazolidinon-derivate als antibiotika, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen | |
| DK633088A (da) | Kollagenaseinhibitorer | |
| ES2188194T3 (es) | 1,8-naftiridin-4(1h)-onas sustituidas como inhibidores de la fosfodiesterasa 4. | |
| DK159148C (da) | Analogifremgangsmaade til fremstilling af tranexamsyrederivater | |
| DE60006099D1 (de) | Chinolinderivate als mek enzym-inhibitoren | |
| PT1259484E (pt) | Carboxamidas uteis como inibidores de proteina de transferencia de triglicerido microsomal e de secrecao de apolipoproteina b | |
| DE69122941D1 (de) | Piperazinderivate | |
| SE9703377D0 (sv) | New compounds | |
| NZ513594A (en) | Heterocyclic compounds, intermediates thereof and elastase inhibitors | |
| ATE357447T1 (de) | Inhibitoren des papilloma-virus | |
| RU2004131645A (ru) | Кремнийсодержащие производные фениламидов, полезные в качестве бактерицидов | |
| ATE117986T1 (de) | Oxysulfonylharnstoff-acat-inhibitoren. | |
| AR031808A1 (es) | 2-piridonas antimicrobianas, sus composiciones y usos | |
| DE60045821D1 (de) | Derivate von aromatische heterocyclen enthaltende integraseinhibitoren | |
| ES8203870A1 (es) | Procedimiento para preparar difenilbutil-1-acilpiperazinas | |
| ATE3111T1 (de) | Verfahren zur herstellung von phenyl-propylmorpholin- und -piperidin-derivaten. | |
| SE8405275D0 (sv) | 1,2-dithiolan derivatives, processes for their production, pharmaceutical compositions containing them and their use | |
| NO914577L (no) | Fremgangsmaate for fremstilling av heterocyklisk substituerte piperazinoalkylbenzoksazin- og -tiazinforbindelser | |
| ATE40117T1 (de) | O-substituierte 3-oxypyridiniumsalze, verfahren zu ihrer herstellung und ihre verwendung als fungizide fuer den pflanzenschutz. | |
| ES448439A1 (es) | Procedimiento para la preparacion de nuevos de diacina. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1345943 Country of ref document: EP |