ATE359789T1 - Verwendung von 4-pyridylmethyl-phthalazin- derivaten zur herstellung eines medikaments zur behandlung von myelodysplastischen syndromen - Google Patents

Verwendung von 4-pyridylmethyl-phthalazin- derivaten zur herstellung eines medikaments zur behandlung von myelodysplastischen syndromen

Info

Publication number
ATE359789T1
ATE359789T1 AT03798175T AT03798175T ATE359789T1 AT E359789 T1 ATE359789 T1 AT E359789T1 AT 03798175 T AT03798175 T AT 03798175T AT 03798175 T AT03798175 T AT 03798175T AT E359789 T1 ATE359789 T1 AT E359789T1
Authority
AT
Austria
Prior art keywords
medication
treatment
production
myelodysplastic syndrome
phthalazine derivatives
Prior art date
Application number
AT03798175T
Other languages
English (en)
Inventor
Margaret Han Dugan
Alan List
Original Assignee
Novartis Pharma Gmbh
Univ Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh, Univ Arizona filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE359789T1 publication Critical patent/ATE359789T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03798175T 2002-09-24 2003-09-23 Verwendung von 4-pyridylmethyl-phthalazin- derivaten zur herstellung eines medikaments zur behandlung von myelodysplastischen syndromen ATE359789T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41317602P 2002-09-24 2002-09-24

Publications (1)

Publication Number Publication Date
ATE359789T1 true ATE359789T1 (de) 2007-05-15

Family

ID=32043216

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03798175T ATE359789T1 (de) 2002-09-24 2003-09-23 Verwendung von 4-pyridylmethyl-phthalazin- derivaten zur herstellung eines medikaments zur behandlung von myelodysplastischen syndromen

Country Status (22)

Country Link
US (1) US20060128716A1 (de)
EP (1) EP1545534B1 (de)
JP (1) JP2006502195A (de)
KR (1) KR20050074450A (de)
CN (1) CN100372535C (de)
AT (1) ATE359789T1 (de)
AU (1) AU2003299065B2 (de)
BR (1) BR0314647A (de)
CA (1) CA2499738A1 (de)
CR (1) CR7754A (de)
DE (1) DE60313344T2 (de)
EC (1) ECSP055700A (de)
ES (1) ES2285251T3 (de)
HR (1) HRP20050281A2 (de)
MX (1) MXPA05003161A (de)
NO (1) NO20051936L (de)
PL (1) PL374696A1 (de)
PT (1) PT1545534E (de)
RS (1) RS20050228A (de)
RU (1) RU2353364C2 (de)
WO (1) WO2004028542A1 (de)
ZA (1) ZA200502212B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1391206B1 (de) * 1997-10-15 2008-07-02 Polarx Biopharmaceuticals, Inc. Pharmazeutische Zusammensetzungen enthaltend Arsentrioxid zur Behandlung von nicht-Hodgkihn-Lymphome
US7915410B2 (en) 2005-09-09 2011-03-29 Bristol-Myers Squibb Company Acyclic IKur inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7132458B2 (en) * 1994-08-10 2006-11-07 Chemaphor Inc. Oxidized carotenoid fractions and ketoaldehyde useful as cell-differentiation inducers, cytostatic agents, and anti-tumor agents
IL115156A (en) * 1994-09-06 2000-07-16 Univ Georgia Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines
RU2136308C1 (ru) * 1994-11-16 1999-09-10 Жемчугов Владислав Евгеньевич Стимулятор роста костно-мозговых клеток человека
CO4950519A1 (es) * 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
ATE329596T1 (de) * 1999-03-30 2006-07-15 Novartis Pharma Gmbh Phthalazinderivate zur behandlung von entzündlicher erkrankungen
AR025068A1 (es) * 1999-08-10 2002-11-06 Bayer Corp Pirazinas sustituidas y piridazinas fusionadas, composicion farmaceutica que las comprenden, uso de dichos compuestos para la manufactura de un medicamentocon actividad inhibidora de angiogenesis
EP1246617B1 (de) * 1999-12-06 2006-09-13 Rhode Island Hospital Verwendung von taurolidin oder taurultam zur herstellung eines medikaments zur behandlung von ovarialkarzinomen

Also Published As

Publication number Publication date
ZA200502212B (en) 2006-02-22
DE60313344D1 (de) 2007-05-31
WO2004028542A1 (en) 2004-04-08
EP1545534A1 (de) 2005-06-29
US20060128716A1 (en) 2006-06-15
CA2499738A1 (en) 2004-04-08
AU2003299065B2 (en) 2006-10-26
RU2005112711A (ru) 2006-02-27
JP2006502195A (ja) 2006-01-19
CN100372535C (zh) 2008-03-05
ES2285251T3 (es) 2007-11-16
ECSP055700A (es) 2005-08-11
MXPA05003161A (es) 2005-09-12
PT1545534E (pt) 2007-06-22
KR20050074450A (ko) 2005-07-18
HRP20050281A2 (en) 2006-07-31
CN1684684A (zh) 2005-10-19
BR0314647A (pt) 2005-08-02
RS20050228A (sr) 2007-08-03
NO20051936L (no) 2005-06-23
DE60313344T2 (de) 2008-01-03
RU2353364C2 (ru) 2009-04-27
AU2003299065A1 (en) 2004-04-19
EP1545534B1 (de) 2007-04-18
CR7754A (es) 2005-12-02
PL374696A1 (en) 2005-10-31

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