ATE363923T1 - Verwendung von flumazenil zur herstellung eines medikaments für die behandlung von kokainabhängigkeit - Google Patents

Verwendung von flumazenil zur herstellung eines medikaments für die behandlung von kokainabhängigkeit

Info

Publication number: ATE363923T1
Authority: AT; Austria
Prior art keywords: flumazenil; treatment; medication; production; cocaine dependence
Prior art date: 2001-02-15

Application number

AT02711879T

Other languages

English (en)

Inventor

Ibanez Juan Jose Legarda

Original Assignee

Hythiam Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-15

Filing date

2002-02-08

Publication date

2007-06-15

2002-02-08 Application filed by Hythiam Inc filed Critical Hythiam Inc

2007-06-15 Application granted granted Critical

2007-06-15 Publication of ATE363923T1 publication Critical patent/ATE363923T1/de

Links

OFBIFZUFASYYRE-UHFFFAOYSA-N flumazenil Chemical compound C1N(C)C(=O)C2=CC(F)=CC=C2N2C=NC(C(=O)OCC)=C21 OFBIFZUFASYYRE-UHFFFAOYSA-N 0.000 title abstract 3
229960004381 flumazenil Drugs 0.000 title abstract 3
239000003814 drug Substances 0.000 title abstract 2
208000022497 Cocaine-Related disease Diseases 0.000 title 1
201000006145 cocaine dependence Diseases 0.000 title 1
229940079593 drug Drugs 0.000 title 1
206010013663 drug dependence Diseases 0.000 title 1
ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 abstract 4
229960003920 cocaine Drugs 0.000 abstract 2

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Addiction (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Neurology (AREA)
Psychiatry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Toxicology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Steroid Compounds (AREA)

AT02711879T 2001-02-15 2002-02-08 Verwendung von flumazenil zur herstellung eines medikaments für die behandlung von kokainabhängigkeit ATE363923T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ES200100342		2001-02-15

Publications (1)

Publication Number	Publication Date
ATE363923T1 true ATE363923T1 (de)	2007-06-15

Family

ID=8496743

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02711879T ATE363923T1 (de)	2001-02-15	2002-02-08	Verwendung von flumazenil zur herstellung eines medikaments für die behandlung von kokainabhängigkeit

Country Status (20)

Country	Link
US (2)	US7186711B2 (de)
EP (1)	EP1378267B1 (de)
JP (2)	JP4272885B2 (de)
KR (1)	KR100712571B1 (de)
CN (1)	CN1327843C (de)
AT (1)	ATE363923T1 (de)
AU (1)	AU2002231811B2 (de)
BR (1)	BR0207866A (de)
CA (1)	CA2436511C (de)
CY (1)	CY1106845T1 (de)
DE (1)	DE60220512T2 (de)
DK (1)	DK1378267T3 (de)
ES (1)	ES2287255T3 (de)
IL (1)	IL157144A0 (de)
MX (1)	MXPA03007281A (de)
NZ (1)	NZ528164A (de)
PT (1)	PT1378267E (de)
RU (1)	RU2322985C2 (de)
UA (1)	UA79586C2 (de)
WO (1)	WO2002064213A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050192271A1 (en) *	2003-07-15	2005-09-01	Hythiam, Inc.	Use of selective chloride channel modulators to treat alcohol and/or stimulant substance abuse
ES2287255T3 (es)	2001-02-15	2007-12-16	Hythiam, Inc.	Uso de flumazenil para producir un medicamento parta el tratamiento de la dependencia a cocaina.
AU2006235318A1 (en)	2005-04-07	2006-10-19	Hythiam, Inc.	Improved methods of and compositions for the prevention of anxiety, substance abuse, and dependence
US7855196B2 (en)	2005-08-22	2010-12-21	Pierre Mainville	Composition comprising a benzodiazepine agonist and a benzodiazepine antagonist
ES2289935B1 (es) *	2006-07-14	2008-12-16	Juan Jose Legarda Ibañez	Empleo de flumazenilo en la elaboracion de un medicamento para el tratamiento de la patologia depresiva.
US20110034442A1 (en) *	2007-08-08	2011-02-10	Jaun Jose Legarda Ibanez	Use and Methods of Use for an Antagonist of the Serotin3 Receptor (5-HT3) and a Selective Modulator of Chloride Channels for the Treatment of Addiction to or Dependence on Medicines/Drugs or Nervous System Disorders
US9396280B2 (en) *	2008-06-23	2016-07-19	Microsoft Technology Licensing, Llc	Command driven web site browsing
WO2012114342A1 (en)	2011-02-23	2012-08-30	Coeruleus Ltd.	Flumazenil complexes, compositions comprising same and uses thereof
US9308616B2 (en)	2013-01-21	2016-04-12	Innovative Finishes LLC	Refurbished component, electronic device including the same, and method of refurbishing a component of an electronic device
AU2014336959A1 (en) *	2013-10-14	2016-05-26	Palmaya Pty Ltd	Compositions and methods of administering same
CN107115359A (zh) *	2016-02-24	2017-09-01	郑恩哲	阻断海洛因或吗啡毒品中毒路径的点滴处方及其应用
EP3661500B1 (de)	2017-07-31	2026-01-07	Novartis AG	Verwendung von mavoglurant bei der reduktion des kokainkonsums oder zur verhinderung eines kokainkonsumrückfalls

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5028611A (en) *	1989-06-29	1991-07-02	The Regents Of The University Of Minnesota	Treatment for cocaine use
SE9100860D0 (sv) *	1991-03-22	1991-03-22	Kabi Pharmacia Ab	New use
US5229120A (en) *	1992-02-05	1993-07-20	Devincent James F	Treatment for cocaine abuse
GB9225859D0 (en) *	1992-12-11	1993-02-03	Smithkline Beecham Plc	Novel treatment
GB9420010D0 (en)	1994-10-01	1994-11-16	Marck Sharp & Dohme Limited	Nucleic acids
WO2000030648A1 (en) *	1998-11-23	2000-06-02	Sepracor Inc.	2-hydroxymethylolanzapine compositions and methods
EP1125579A3 (de) *	2000-01-18	2003-01-02	Pfizer Products Inc.	Verwendungen von AGRP-Melanocortinrezeptorbindung modulierenden Verbindungen
ES2287255T3 (es) *	2001-02-15	2007-12-16	Hythiam, Inc.	Uso de flumazenil para producir un medicamento parta el tratamiento de la dependencia a cocaina.
US6740677B2 (en)	2002-08-19	2004-05-25	Hong Xue	Methods of treating benzodiazepine site (BZD-S) associated syndromes using 2′ hydroxyflavonoids

2002
- 2002-02-08 ES ES02711879T patent/ES2287255T3/es not_active Expired - Lifetime
- 2002-02-08 RU RU2003127718/15A patent/RU2322985C2/ru not_active IP Right Cessation
- 2002-02-08 DK DK02711879T patent/DK1378267T3/da active
- 2002-02-08 JP JP2002564005A patent/JP4272885B2/ja not_active Expired - Lifetime
- 2002-02-08 KR KR1020037010718A patent/KR100712571B1/ko not_active Expired - Fee Related
- 2002-02-08 NZ NZ528164A patent/NZ528164A/xx unknown
- 2002-02-08 MX MXPA03007281A patent/MXPA03007281A/es active IP Right Grant
- 2002-02-08 WO PCT/ES2002/000061 patent/WO2002064213A1/es not_active Ceased
- 2002-02-08 EP EP02711879A patent/EP1378267B1/de not_active Expired - Lifetime
- 2002-02-08 BR BR0207866-0A patent/BR0207866A/pt not_active Application Discontinuation
- 2002-02-08 IL IL15714402A patent/IL157144A0/xx unknown
- 2002-02-08 CN CNB028049411A patent/CN1327843C/zh not_active Expired - Fee Related
- 2002-02-08 AT AT02711879T patent/ATE363923T1/de active
- 2002-02-08 PT PT02711879T patent/PT1378267E/pt unknown
- 2002-02-08 CA CA002436511A patent/CA2436511C/en not_active Expired - Fee Related
- 2002-02-08 AU AU2002231811A patent/AU2002231811B2/en not_active Ceased
- 2002-02-08 DE DE60220512T patent/DE60220512T2/de not_active Expired - Lifetime
- 2002-08-02 UA UA2003098460A patent/UA79586C2/uk unknown
2003
- 2003-07-15 US US10/622,068 patent/US7186711B2/en not_active Expired - Lifetime
2006
- 2006-12-22 US US11/615,460 patent/US20070142364A1/en not_active Abandoned
2007
- 2007-09-05 CY CY20071101148T patent/CY1106845T1/el unknown
2008
- 2008-04-30 JP JP2008117980A patent/JP2008201799A/ja active Pending

Also Published As

Publication number	Publication date
EP1378267A1 (de)	2004-01-07
DK1378267T3 (da)	2007-10-08
US20060122219A1 (en)	2006-06-08
JP2008201799A (ja)	2008-09-04
RU2003127718A (ru)	2005-01-27
CN1491125A (zh)	2004-04-21
US7186711B2 (en)	2007-03-06
MXPA03007281A (es)	2005-01-25
EP1378267B1 (de)	2007-06-06
CY1106845T1 (el)	2012-05-23
HK1061817A1 (en)	2004-10-08
ES2287255T3 (es)	2007-12-16
CN1327843C (zh)	2007-07-25
CA2436511A1 (en)	2002-08-22
KR20040010592A (ko)	2004-01-31
PT1378267E (pt)	2007-09-11
DE60220512T2 (de)	2008-02-07
NZ528164A (en)	2006-03-31
AU2002231811B2 (en)	2006-02-16
BR0207866A (pt)	2004-03-23
JP4272885B2 (ja)	2009-06-03
US20070142364A1 (en)	2007-06-21
KR100712571B1 (ko)	2007-05-02
WO2002064213A1 (es)	2002-08-22
IL157144A0 (en)	2004-02-08
JP2004521904A (ja)	2004-07-22
UA79586C2 (en)	2007-07-10
RU2322985C2 (ru)	2008-04-27
CA2436511C (en)	2009-08-04
DE60220512D1 (de)	2007-07-19

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2007-11-15

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