ATE363923T1 - Verwendung von flumazenil zur herstellung eines medikaments für die behandlung von kokainabhängigkeit - Google Patents

Verwendung von flumazenil zur herstellung eines medikaments für die behandlung von kokainabhängigkeit

Info

Publication number: ATE363923T1
Authority: AT; Austria
Prior art keywords: flumazenil; treatment; medication; production; cocaine dependence
Prior art date: 2001-02-15

Application number

AT02711879T

Other languages

English (en)

Inventor

Ibanez Juan Jose Legarda

Original Assignee

Hythiam Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-15

Filing date

2002-02-08

Publication date

2007-06-15

2002-02-08 Application filed by Hythiam Inc filed Critical Hythiam Inc

2007-06-15 Application granted granted Critical

2007-06-15 Publication of ATE363923T1 publication Critical patent/ATE363923T1/de

Links

OFBIFZUFASYYRE-UHFFFAOYSA-N flumazenil Chemical compound C1N(C)C(=O)C2=CC(F)=CC=C2N2C=NC(C(=O)OCC)=C21 OFBIFZUFASYYRE-UHFFFAOYSA-N 0.000 title abstract 3
229960004381 flumazenil Drugs 0.000 title abstract 3
239000003814 drug Substances 0.000 title abstract 2
208000022497 Cocaine-Related disease Diseases 0.000 title 1
201000006145 cocaine dependence Diseases 0.000 title 1
229940079593 drug Drugs 0.000 title 1
206010013663 drug dependence Diseases 0.000 title 1
ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 abstract 4
229960003920 cocaine Drugs 0.000 abstract 2

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Addiction (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Neurology (AREA)
Psychiatry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Toxicology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Steroid Compounds (AREA)

AT02711879T 2001-02-15 2002-02-08 Verwendung von flumazenil zur herstellung eines medikaments für die behandlung von kokainabhängigkeit ATE363923T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ES200100342		2001-02-15

Publications (1)

Publication Number	Publication Date
ATE363923T1 true ATE363923T1 (de)	2007-06-15

Family

ID=8496743

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02711879T ATE363923T1 (de)	2001-02-15	2002-02-08	Verwendung von flumazenil zur herstellung eines medikaments für die behandlung von kokainabhängigkeit

Country Status (20)

Country	Link
US (2)	US7186711B2 (de)
EP (1)	EP1378267B1 (de)
JP (2)	JP4272885B2 (de)
KR (1)	KR100712571B1 (de)
CN (1)	CN1327843C (de)
AT (1)	ATE363923T1 (de)
AU (1)	AU2002231811B2 (de)
BR (1)	BR0207866A (de)
CA (1)	CA2436511C (de)
CY (1)	CY1106845T1 (de)
DE (1)	DE60220512T2 (de)
DK (1)	DK1378267T3 (de)
ES (1)	ES2287255T3 (de)
IL (1)	IL157144A0 (de)
MX (1)	MXPA03007281A (de)
NZ (1)	NZ528164A (de)
PT (1)	PT1378267E (de)
RU (1)	RU2322985C2 (de)
UA (1)	UA79586C2 (de)
WO (1)	WO2002064213A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050192271A1 (en) *	2003-07-15	2005-09-01	Hythiam, Inc.	Use of selective chloride channel modulators to treat alcohol and/or stimulant substance abuse
CA2436511C (en) *	2001-02-15	2009-08-04	Juan Jose Legarda Ibanez	Use of flumazenil to produce a medicament for the treatment of cocaine dependency
JP2008538748A (ja)	2005-04-07	2008-11-06	ハイシアム，インコーポレイテッド	不安、物質乱用及び依存の予防のための改良型方法及び組成物
US7855196B2 (en)	2005-08-22	2010-12-21	Pierre Mainville	Composition comprising a benzodiazepine agonist and a benzodiazepine antagonist
ES2289935B1 (es) *	2006-07-14	2008-12-16	Juan Jose Legarda Ibañez	Empleo de flumazenilo en la elaboracion de un medicamento para el tratamiento de la patologia depresiva.
US20110034442A1 (en) *	2007-08-08	2011-02-10	Jaun Jose Legarda Ibanez	Use and Methods of Use for an Antagonist of the Serotin3 Receptor (5-HT3) and a Selective Modulator of Chloride Channels for the Treatment of Addiction to or Dependence on Medicines/Drugs or Nervous System Disorders
US9396280B2 (en) *	2008-06-23	2016-07-19	Microsoft Technology Licensing, Llc	Command driven web site browsing
ES2702848T3 (es)	2011-02-23	2019-03-05	Coeruleus Ltd	Complejos de flumazenil, composiciones que los comprenden y usos de los mismos
US9308616B2 (en)	2013-01-21	2016-04-12	Innovative Finishes LLC	Refurbished component, electronic device including the same, and method of refurbishing a component of an electronic device
WO2015054730A1 (en) *	2013-10-14	2015-04-23	Palmaya Pty Ltd	Compositions and methods of administering same
CN107115359A (zh) *	2016-02-24	2017-09-01	郑恩哲	阻断海洛因或吗啡毒品中毒路径的点滴处方及其应用
EP3661500B1 (de)	2017-07-31	2026-01-07	Novartis AG	Verwendung von mavoglurant bei der reduktion des kokainkonsums oder zur verhinderung eines kokainkonsumrückfalls

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5028611A (en) *	1989-06-29	1991-07-02	The Regents Of The University Of Minnesota	Treatment for cocaine use
SE9100860D0 (sv) *	1991-03-22	1991-03-22	Kabi Pharmacia Ab	New use
US5229120A (en) *	1992-02-05	1993-07-20	Devincent James F	Treatment for cocaine abuse
GB9225859D0 (en) *	1992-12-11	1993-02-03	Smithkline Beecham Plc	Novel treatment
GB9420010D0 (en)	1994-10-01	1994-11-16	Marck Sharp & Dohme Limited	Nucleic acids
EP1133299A1 (de) *	1998-11-23	2001-09-19	Sepracor Inc.	2-hydroxymethylolanzapine enthaltende zusammensetzungen und verfahren
EP1125579A3 (de) *	2000-01-18	2003-01-02	Pfizer Products Inc.	Verwendungen von AGRP-Melanocortinrezeptorbindung modulierenden Verbindungen
CA2436511C (en)	2001-02-15	2009-08-04	Juan Jose Legarda Ibanez	Use of flumazenil to produce a medicament for the treatment of cocaine dependency
US6740677B2 (en)	2002-08-19	2004-05-25	Hong Xue	Methods of treating benzodiazepine site (BZD-S) associated syndromes using 2′ hydroxyflavonoids

2002
- 2002-02-08 CA CA002436511A patent/CA2436511C/en not_active Expired - Fee Related
- 2002-02-08 WO PCT/ES2002/000061 patent/WO2002064213A1/es not_active Ceased
- 2002-02-08 PT PT02711879T patent/PT1378267E/pt unknown
- 2002-02-08 MX MXPA03007281A patent/MXPA03007281A/es active IP Right Grant
- 2002-02-08 JP JP2002564005A patent/JP4272885B2/ja not_active Expired - Lifetime
- 2002-02-08 ES ES02711879T patent/ES2287255T3/es not_active Expired - Lifetime
- 2002-02-08 BR BR0207866-0A patent/BR0207866A/pt not_active Application Discontinuation
- 2002-02-08 NZ NZ528164A patent/NZ528164A/xx unknown
- 2002-02-08 EP EP02711879A patent/EP1378267B1/de not_active Expired - Lifetime
- 2002-02-08 CN CNB028049411A patent/CN1327843C/zh not_active Expired - Fee Related
- 2002-02-08 AU AU2002231811A patent/AU2002231811B2/en not_active Ceased
- 2002-02-08 AT AT02711879T patent/ATE363923T1/de active
- 2002-02-08 KR KR1020037010718A patent/KR100712571B1/ko not_active Expired - Fee Related
- 2002-02-08 DK DK02711879T patent/DK1378267T3/da active
- 2002-02-08 IL IL15714402A patent/IL157144A0/xx unknown
- 2002-02-08 DE DE60220512T patent/DE60220512T2/de not_active Expired - Lifetime
- 2002-02-08 RU RU2003127718/15A patent/RU2322985C2/ru not_active IP Right Cessation
- 2002-08-02 UA UA2003098460A patent/UA79586C2/uk unknown
2003
- 2003-07-15 US US10/622,068 patent/US7186711B2/en not_active Expired - Lifetime
2006
- 2006-12-22 US US11/615,460 patent/US20070142364A1/en not_active Abandoned
2007
- 2007-09-05 CY CY20071101148T patent/CY1106845T1/el unknown
2008
- 2008-04-30 JP JP2008117980A patent/JP2008201799A/ja active Pending

Also Published As

Publication number	Publication date
KR100712571B1 (ko)	2007-05-02
HK1061817A1 (en)	2004-10-08
EP1378267B1 (de)	2007-06-06
PT1378267E (pt)	2007-09-11
NZ528164A (en)	2006-03-31
US20070142364A1 (en)	2007-06-21
DE60220512T2 (de)	2008-02-07
WO2002064213A1 (es)	2002-08-22
DK1378267T3 (da)	2007-10-08
JP2008201799A (ja)	2008-09-04
MXPA03007281A (es)	2005-01-25
DE60220512D1 (de)	2007-07-19
JP4272885B2 (ja)	2009-06-03
AU2002231811B2 (en)	2006-02-16
KR20040010592A (ko)	2004-01-31
CN1491125A (zh)	2004-04-21
CA2436511A1 (en)	2002-08-22
RU2322985C2 (ru)	2008-04-27
US20060122219A1 (en)	2006-06-08
IL157144A0 (en)	2004-02-08
RU2003127718A (ru)	2005-01-27
US7186711B2 (en)	2007-03-06
EP1378267A1 (de)	2004-01-07
BR0207866A (pt)	2004-03-23
CN1327843C (zh)	2007-07-25
JP2004521904A (ja)	2004-07-22
CY1106845T1 (el)	2012-05-23
UA79586C2 (en)	2007-07-10
ES2287255T3 (es)	2007-12-16
CA2436511C (en)	2009-08-04

Similar Documents

Publication	Publication Date	Title
YU71901A (sh)	2005-07-19	NOVE VRSTE LEKOVITIH KOMPOZICIJA NA BAZI JEDINJENJA KOJA DELUJU ANTIHOLINERGIJSKI I beta-MIMETIKA
ATE399553T1 (de)	2008-07-15	Pharmazeutische zusammensetzungen mit dextromethorphan und chinidin zur behandlung von neurologischen erkrankungen
ATE355374T1 (de)	2006-03-15	Therapeutische agentien und methoden ihrer verwendung zur behandlung von amyloidogenen erkrankungen
DE602004029580D1 (de)	2010-11-25	Substituierte indolderivate für eine pharmazeutische zusammensetzung zur behandlung von atemwegserkrankungen
ATE414524T1 (de)	2008-12-15	Verwendung von myoblasten zur herstellung eines medikaments zur behandlung der stressbedingten harninkontinenz
ATE363923T1 (de)	2007-06-15	Verwendung von flumazenil zur herstellung eines medikaments für die behandlung von kokainabhängigkeit
MY147643A (en)	2012-12-31	Use of benzo-fused heterocycle sulfamide derivatives for the treatment of mania and bipolar disorder
ATE302774T1 (de)	2005-09-15	Arzneimittel enthaltend betamimetika und ein neues anticholinergikum
DE69934813D1 (de)	2007-02-22	Verwendung von gaba analogen zur herstellung eines arzneimittels zur behandlung von manie und bipolaren erkrankungen
ATE383853T1 (de)	2008-02-15	Arylessigsäuren und verwandte verbindungen zur behandlung von alzheimer-krankheit
ATE338575T1 (de)	2006-09-15	Verwendung von flumazenil bei der entwicklung eines arzneimittels zur behandlung von alkoholabhängigkeit
DE60203847D1 (de)	2005-06-02	Verbindungen enthaltend S-Tofisopam sowie Verwendung dieser Verbindungen zur Herstellung eines Medikamentes zur Behandlung oder Prophylaxe von Krämpfen und Anfällen
DE59914712D1 (de)	2008-05-08	Verwendung von inhibitoren des kqt1-kanals zur herstellung eines medikaments zur behandlung von krankheiten, die durch helminthen und ektoparasiten hervorgerufen werden
ATE191849T1 (de)	2000-05-15	Verwendung von (s)-(-)-alpha-ethyl-2-oxo-1- pyrrolidinacetamid zur herstellung eines medikaments zur behandlung von angst
ATE289816T1 (de)	2005-03-15	Verwendung von mirtazapine zur herstellung eines medikaments zur behandlung von schlafapnoen
DE69635298D1 (de)	2006-03-02	Verwendung von Acetylsalicylsäuren zur Herstellung eines Medikaments für die Behandlung von Hautverletzungen
ATE252383T1 (de)	2003-11-15	Verwendung von 2-methyl-thiazolidin-2,4- dicarbonsäure und / oder ihrer physiologisch verträglichen salze zur herstellung eines medikaments zur behandlung von krebserkrankungen
ATE419012T1 (de)	2009-01-15	Verwendung von 2,5-dihydroxybenzolsulfonsäure- derivaten bei der herstellung eines medikaments zur verstärkung der wirkung anderer arzneimittel zur behandlung der erektilen dysfunktion
ATE464048T1 (de)	2010-04-15	Behandlung von alzheimer-krankheit und verwandten zuständen
ATE294582T1 (de)	2005-05-15	Verwendung von alpha-1-adrenorezeptor- antagonisten zur herstellung eines medikaments für die vorbeugung und die behandlung von krebs
ATE408602T1 (de)	2008-10-15	Monohyroxycarbamezepin zur verwendung bei der herstellung eines medikaments zur behandlung von affektiver psychose, aufmerksamkeits störungen und neuropathischen schmerzen
ATE492285T1 (de)	2011-01-15	Verwendung von kahalalide verbindungen zur herstellung eines arzneimittels zur behandlung von psoriasis
ATE234613T1 (de)	2003-04-15	Verwendung von comt inhibitoren zur herstellung eines arzneimittels zur vorbeugung von diabetischen vaskulären funktionsstörungen
ATE69949T1 (de)	1991-12-15	Liposomen mit inhalativen allergenen zur behandlung von allergien, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
ATE479423T1 (de)	2010-09-15	Vorrichtung für die topische anwendung des medizinischen ozons zur behandlung von erkrankungen der mundhöhle

Legal Events

Date

Code

Title

Description

2007-11-15

UEP

Publication of translation of european patent specification

Ref document number: 1378267

Country of ref document: EP