ATE359841T1 - Vorgefüllte spritze und fertigungsverfahren für den dazugehörigen spritzenzylinder - Google Patents
Vorgefüllte spritze und fertigungsverfahren für den dazugehörigen spritzenzylinderInfo
- Publication number
- ATE359841T1 ATE359841T1 AT04001191T AT04001191T ATE359841T1 AT E359841 T1 ATE359841 T1 AT E359841T1 AT 04001191 T AT04001191 T AT 04001191T AT 04001191 T AT04001191 T AT 04001191T AT E359841 T1 ATE359841 T1 AT E359841T1
- Authority
- AT
- Austria
- Prior art keywords
- resin
- barrel
- injecting
- layer
- barrier property
- Prior art date
Links
- 229940071643 prefilled syringe Drugs 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000004888 barrier function Effects 0.000 abstract 3
- 229920005672 polyolefin resin Polymers 0.000 abstract 3
- 229920005989 resin Polymers 0.000 abstract 3
- 239000011347 resin Substances 0.000 abstract 3
- 238000002347 injection Methods 0.000 abstract 2
- 239000007924 injection Substances 0.000 abstract 2
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/16—Making multilayered or multicoloured articles
- B29C45/1603—Multi-way nozzles specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/16—Making multilayered or multicoloured articles
- B29C45/1642—Making multilayered or multicoloured articles having a "sandwich" structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
- B29K2023/04—Polymers of ethylene
- B29K2023/08—Copolymers of ethylene
- B29K2023/086—EVOH, i.e. ethylene vinyl alcohol copolymer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
- B29K2995/0037—Other properties
- B29K2995/0065—Permeability to gases
- B29K2995/0067—Permeability to gases non-permeable
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
- B29L2031/7544—Injection needles, syringes
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Manufacturing & Machinery (AREA)
- Mechanical Engineering (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Injection Moulding Of Plastics Or The Like (AREA)
- Packages (AREA)
- Wrappers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003019401A JP2004229750A (ja) | 2003-01-28 | 2003-01-28 | プレフィルドシリンジ及びそのバレルの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE359841T1 true ATE359841T1 (de) | 2007-05-15 |
Family
ID=32652854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04001191T ATE359841T1 (de) | 2003-01-28 | 2004-01-21 | Vorgefüllte spritze und fertigungsverfahren für den dazugehörigen spritzenzylinder |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7998120B2 (de) |
| EP (1) | EP1442762B1 (de) |
| JP (1) | JP2004229750A (de) |
| AT (1) | ATE359841T1 (de) |
| DE (1) | DE602004005902T2 (de) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7824697B2 (en) | 2004-07-12 | 2010-11-02 | Board Of Regents, The University Of Texas System | High concentration baclofen preparations |
| CN101247843B (zh) * | 2005-08-22 | 2010-09-29 | 尼普洛株式会社 | 预填充式注射器 |
| US20150258279A1 (en) | 2008-03-18 | 2015-09-17 | Mallinckrodt Llc | Intrathecal baclofen pharmaceutical dosage forms and related delivery system |
| US8969414B2 (en) | 2009-02-06 | 2015-03-03 | Mallinckrodt Llc | Intrathecal baclofen pharmaceutical dosage forms with fewer degradation products |
| JP5933975B2 (ja) | 2008-11-12 | 2016-06-15 | メディミューン,エルエルシー | 抗体製剤 |
| EP2251455B1 (de) | 2009-05-13 | 2017-09-06 | SiO2 Medical Products, Inc. | PECVD-Beschichtung mittels siliciumorganischem Vorläufer |
| US7985188B2 (en) | 2009-05-13 | 2011-07-26 | Cv Holdings Llc | Vessel, coating, inspection and processing apparatus |
| GB2471304B (en) | 2009-06-24 | 2013-12-11 | Oval Medical Technologies Ltd | A pre-filled syringe or autoinjector |
| US9458536B2 (en) | 2009-07-02 | 2016-10-04 | Sio2 Medical Products, Inc. | PECVD coating methods for capped syringes, cartridges and other articles |
| WO2011035449A2 (de) * | 2009-09-22 | 2011-03-31 | Medmix System Ag | Versiegelter behälter mit verschiebbarem kolben |
| WO2011107954A2 (en) * | 2010-03-03 | 2011-09-09 | Atul Sardana | Single use safety syringe with spring actuated needle stick injury prevention and auto disable mechanism |
| US11624115B2 (en) | 2010-05-12 | 2023-04-11 | Sio2 Medical Products, Inc. | Syringe with PECVD lubrication |
| WO2011143509A1 (en) | 2010-05-12 | 2011-11-17 | Cv Holdings, Llc | Vessel outgassing inspection methods |
| WO2012022734A2 (en) | 2010-08-16 | 2012-02-23 | Medimmune Limited | Anti-icam-1 antibodies and methods of use |
| US9878101B2 (en) | 2010-11-12 | 2018-01-30 | Sio2 Medical Products, Inc. | Cyclic olefin polymer vessels and vessel coating methods |
| US9272095B2 (en) | 2011-04-01 | 2016-03-01 | Sio2 Medical Products, Inc. | Vessels, contact surfaces, and coating and inspection apparatus and methods |
| WO2013009897A1 (en) | 2011-07-11 | 2013-01-17 | Medpro Safety Products, Inc. | Fluid delivery device and methods |
| JP6080112B2 (ja) | 2011-10-07 | 2017-02-15 | 三菱瓦斯化学株式会社 | 医療用包装容器 |
| CN103930595A (zh) | 2011-11-11 | 2014-07-16 | Sio2医药产品公司 | 用于药物包装的钝化、pH保护性或润滑性涂层、涂布方法以及设备 |
| US11116695B2 (en) | 2011-11-11 | 2021-09-14 | Sio2 Medical Products, Inc. | Blood sample collection tube |
| DE102012008297A1 (de) * | 2011-11-16 | 2013-05-16 | Lts Lohmann Therapie-Systeme Ag | Zylinder-Kolben-Einheit mit doppelwandigem Zylinder |
| CN103958604B (zh) | 2011-11-25 | 2016-05-04 | 三菱瓦斯化学株式会社 | 吸氧性树脂组合物及使用其的吸氧性成型体、以及使用它们的多层体、容器、注射成型体及医疗用容器 |
| EP2792713B1 (de) | 2011-12-16 | 2020-01-15 | Mitsubishi Gas Chemical Company, Inc. | Aus sauerstoffabsorbierender harzzusammensetzung erhältliches sauerstoffabsorbierendes harzgeformtes element, sowie mehrschichtkörper, behälter, injektionsgeformtes element und medizinischer behälter aus der zusammensetzung |
| US9732167B2 (en) | 2012-02-08 | 2017-08-15 | Mitsubishi Gas Chemical Company, Inc. | Oxygen-absorbing resin composition and oxygen-absorbing multilayer body using same, and molded article and medical container using these |
| WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
| US9265889B2 (en) | 2012-04-25 | 2016-02-23 | Adar Medtech, Inc. | Prefilled medical injection device |
| US10780228B2 (en) | 2012-05-07 | 2020-09-22 | Medline Industries, Inc. | Prefilled container systems |
| EP2846856A1 (de) | 2012-05-09 | 2015-03-18 | SiO2 Medical Products, Inc. | Inspektionsverfahren für pecvd-beschichtungen |
| CA2887352A1 (en) | 2012-05-09 | 2013-11-14 | Sio2 Medical Products, Inc. | Saccharide protective coating for pharmaceutical package |
| US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
| US8870028B2 (en) | 2012-05-25 | 2014-10-28 | Restek Corporation | Dispensing device |
| CN106170582A (zh) | 2012-07-03 | 2016-11-30 | Sio2医药产品公司 | 药物包装的SiOx 阻隔物和涂布方法 |
| US20150297800A1 (en) | 2012-07-03 | 2015-10-22 | Sio2 Medical Products, Inc. | SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS |
| FR2994851B1 (fr) * | 2012-09-04 | 2015-08-21 | Rexam Healthcare La Verpillier | Dispositif d'injection de liquide pharmaceutique configure pour etre pre-rempli |
| JP2014068767A (ja) * | 2012-09-28 | 2014-04-21 | Mitsubishi Gas Chemical Co Inc | 医療用多層容器 |
| JP6509734B2 (ja) | 2012-11-01 | 2019-05-08 | エスアイオーツー・メディカル・プロダクツ・インコーポレイテッド | 皮膜検査方法 |
| US9903782B2 (en) | 2012-11-16 | 2018-02-27 | Sio2 Medical Products, Inc. | Method and apparatus for detecting rapid barrier coating integrity characteristics |
| WO2014085348A2 (en) | 2012-11-30 | 2014-06-05 | Sio2 Medical Products, Inc. | Controlling the uniformity of pecvd deposition on medical syringes, cartridges, and the like |
| US9764093B2 (en) | 2012-11-30 | 2017-09-19 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition |
| ES2882063T3 (es) | 2012-12-03 | 2021-12-01 | Novobiotic Pharmaceuticals Llc | Nuevo depsipéptido y usos del mismo |
| US9301587B2 (en) | 2013-01-14 | 2016-04-05 | Stephen D'Amico | Hair color (or dye) storage, dispensing and measurement (or measuring) system |
| WO2014112113A1 (ja) * | 2013-01-21 | 2014-07-24 | テルモ株式会社 | 注射筒収納容器 |
| EP2961858B1 (de) | 2013-03-01 | 2022-09-07 | Si02 Medical Products, Inc. | Beschichtete spritze. |
| KR20150126393A (ko) | 2013-03-06 | 2015-11-11 | 미츠비시 가스 가가쿠 가부시키가이샤 | 산소 흡수성 다층체, 산소 흡수성 용기, 산소 흡수성 밀폐 용기, 산소 흡수성 ptp 포장체, 및 이들을 이용한 보존 방법 |
| WO2014136918A1 (ja) | 2013-03-06 | 2014-09-12 | 三菱瓦斯化学株式会社 | 酸素吸収性医療用多層容器及びバイオ医薬の保存方法 |
| US9937099B2 (en) | 2013-03-11 | 2018-04-10 | Sio2 Medical Products, Inc. | Trilayer coated pharmaceutical packaging with low oxygen transmission rate |
| CN105392916B (zh) | 2013-03-11 | 2019-03-08 | Sio2医药产品公司 | 涂布包装材料 |
| WO2014140095A1 (en) | 2013-03-14 | 2014-09-18 | Becton Dickinson France S.A.S. | Injectable morphine formulations |
| KR20150129033A (ko) | 2013-03-14 | 2015-11-18 | 애브비 인코포레이티드 | 저 산성 종 조성물 및 이의 제조 및 사용 방법 |
| CA2899449A1 (en) | 2013-03-14 | 2014-10-02 | Abbvie Inc. | Low acidic species compositions and methods for producing the same using displacement chromatography |
| ES2695158T3 (es) | 2013-03-14 | 2019-01-02 | Fresenius Kabi Deutschland Gmbh | Sistema de envasado para fármacos sensibles al oxígeno |
| EP2971227B1 (de) | 2013-03-15 | 2017-11-15 | Si02 Medical Products, Inc. | Beschichtungsverfahren. |
| EP4137139A1 (de) | 2013-07-10 | 2023-02-22 | Matrix Biology Institute | Hyaluronanzusammensetzungen mit hoher elastizität und verwendungen davon |
| WO2015050959A1 (en) | 2013-10-01 | 2015-04-09 | Yale University | Anti-kit antibodies and methods of use thereof |
| JP2015073635A (ja) * | 2013-10-07 | 2015-04-20 | 三菱瓦斯化学株式会社 | 多層シリンジバレル及びプレフィルドシリンジ |
| CA2927835A1 (en) | 2013-12-06 | 2015-06-11 | Genentech, Inc. | Apparatus and methods for low-volume medicament delivery |
| KR102348201B1 (ko) * | 2014-02-10 | 2022-01-10 | 미츠비시 가스 가가쿠 가부시키가이샤 | 주사기 배럴의 제조 방법 |
| US11066745B2 (en) | 2014-03-28 | 2021-07-20 | Sio2 Medical Products, Inc. | Antistatic coatings for plastic vessels |
| WO2015147305A1 (ja) * | 2014-03-28 | 2015-10-01 | テルモ株式会社 | 包装された薬剤充填容器体 |
| US20170226552A1 (en) | 2014-07-03 | 2017-08-10 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using cobalt |
| WO2016007764A1 (en) | 2014-07-09 | 2016-01-14 | Abbvie Inc. | Methods for modulating the glycosylation profile of recombinant proteins using non-commonly used sugars |
| KR102455905B1 (ko) * | 2014-10-30 | 2022-10-17 | 추가이 세이야쿠 가부시키가이샤 | 시린지 캡을 구비한, 침 부착 프리필드 시린지 제제 |
| BR112017008658A2 (pt) | 2014-10-30 | 2017-12-19 | Hoffmann La Roche | seringa e método de preparação da mesma |
| WO2016144773A1 (en) | 2015-03-06 | 2016-09-15 | Abbvie Inc. | Arabinosylated glycoproteins |
| US11077233B2 (en) | 2015-08-18 | 2021-08-03 | Sio2 Medical Products, Inc. | Pharmaceutical and other packaging with low oxygen transmission rate |
| ES2871199T3 (es) | 2015-09-24 | 2021-10-28 | Matrix Biology Inst | Composiciones de hialuronano de alta elasticidad y métodos de uso de las mismas |
| EP3360530B1 (de) * | 2015-10-09 | 2020-02-12 | Mitsubishi Gas Chemical Company, Inc. | Mehrschichtiger behälter zur medizinischen verwendung und verfahren zur herstellung eines mehrschichtigen behälters zur medizinische verwendung |
| EP3862384A3 (de) | 2015-11-16 | 2022-04-13 | Si02 Medical Products, Inc. | Polymersubstrat mit einer oberfläche mit reduzierter haftung von biomolekülen und thermoplastische gegenstände aus diesem substrat |
| EP3418208B1 (de) | 2016-02-16 | 2021-11-03 | Mitsubishi Gas Chemical Company, Inc. | Laminatbehälter und anwendung dafür |
| WO2017147003A1 (en) | 2016-02-26 | 2017-08-31 | Novobiotic Pharmaceuticals, Llc | Novel macrocyclic antibiotics and uses thereof |
| WO2017188267A1 (ja) | 2016-04-25 | 2017-11-02 | テルモ株式会社 | プレフィルドシリンジ用のシリンジ本体、シリンジシステム及びプレフィルドシリンジ |
| US11628257B2 (en) * | 2016-07-11 | 2023-04-18 | Becton Dickinson France | Method for reducing an amount of subvisible particles in a pharmaceutical composition |
| CN106584771A (zh) * | 2016-10-19 | 2017-04-26 | 广州华研精密机械有限公司 | 一种注射筒的注塑成型工艺 |
| US11203616B2 (en) | 2017-04-04 | 2021-12-21 | Novobiotic Pharmaceuticals, Llc | Depsipeptides and uses thereof |
| PT3659594T (pt) | 2018-11-30 | 2020-12-28 | Stegemann Klaus | Uma solução estéril com uma seringa de aplicação que contém um agente ativo médico e processo para a sua disponibilização |
| CN112549420B (zh) * | 2020-11-05 | 2022-10-25 | 山东永聚医药科技有限公司 | 高分子预灌封注射器的制备工艺 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3375825A (en) * | 1965-09-02 | 1968-04-02 | Becton Dickinson Co | Prefilled syringe |
| AU549286B2 (en) | 1981-01-22 | 1986-01-23 | Toyo Boseki K.K. | Blow moulded multiply vessel |
| US5554125A (en) * | 1987-07-08 | 1996-09-10 | Reynolds; David L. | Prefilled vial syringe |
| US5131830A (en) * | 1987-10-30 | 1992-07-21 | Nissei Asb Machine Co., Ltd. | Multi-layer molding nozzle |
| US5125898A (en) * | 1990-03-22 | 1992-06-30 | Harry Kaufhold, Jr. | Disposable syringe with automatic needle retraction |
| DE4438360C2 (de) * | 1994-10-27 | 1999-05-20 | Schott Glas | Vorfüllbare partikelarme, sterile Einmalspritze für die Injektion von Präparaten und Verfahren zu ihrer Herstellung |
| JP3623294B2 (ja) * | 1995-11-28 | 2005-02-23 | 株式会社新素材総合研究所 | 電解質液が収容された医療用容器及びその製造方法 |
| JPH09173450A (ja) * | 1995-12-26 | 1997-07-08 | Nissho Corp | プレフィルドシリンジ |
| JPH1057446A (ja) | 1996-08-23 | 1998-03-03 | Material Eng Tech Lab Inc | ガスバリアー性を有する薬剤容器及びその製造方法 |
| US6053895A (en) * | 1996-11-05 | 2000-04-25 | Schering Aktiengesellschaft | Syringe with a new and improved plug |
| JPH11332984A (ja) | 1998-05-26 | 1999-12-07 | Terumo Corp | 薬液入りシリンジ |
| JP2001112867A (ja) * | 1999-10-18 | 2001-04-24 | Terumo Corp | 薬剤入りシリンジ |
| US20030032928A1 (en) * | 2000-03-02 | 2003-02-13 | Morihiro Sudo | Prefilled syringe assembly |
| CN101816561A (zh) * | 2001-06-18 | 2010-09-01 | 贝克顿迪肯森公司 | 多层容器和关于形成多层容器的加工过程 |
| JP2003199827A (ja) * | 2001-12-28 | 2003-07-15 | Terumo Corp | シリンジ |
-
2003
- 2003-01-28 JP JP2003019401A patent/JP2004229750A/ja active Pending
-
2004
- 2004-01-21 DE DE602004005902T patent/DE602004005902T2/de not_active Expired - Lifetime
- 2004-01-21 AT AT04001191T patent/ATE359841T1/de not_active IP Right Cessation
- 2004-01-21 EP EP04001191A patent/EP1442762B1/de not_active Expired - Lifetime
- 2004-01-23 US US10/762,530 patent/US7998120B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004229750A (ja) | 2004-08-19 |
| US20040267194A1 (en) | 2004-12-30 |
| EP1442762A2 (de) | 2004-08-04 |
| DE602004005902T2 (de) | 2008-01-17 |
| DE602004005902D1 (de) | 2007-05-31 |
| EP1442762A3 (de) | 2005-09-28 |
| EP1442762B1 (de) | 2007-04-18 |
| US7998120B2 (en) | 2011-08-16 |
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