ATE360071T1 - Rezeptor für ein toxin aus bacillus anthracis - Google Patents

Rezeptor für ein toxin aus bacillus anthracis

Info

Publication number
ATE360071T1
ATE360071T1 AT01986969T AT01986969T ATE360071T1 AT E360071 T1 ATE360071 T1 AT E360071T1 AT 01986969 T AT01986969 T AT 01986969T AT 01986969 T AT01986969 T AT 01986969T AT E360071 T1 ATE360071 T1 AT E360071T1
Authority
AT
Austria
Prior art keywords
anthrax toxin
polypeptides
present
receptor
polynucleotides
Prior art date
Application number
AT01986969T
Other languages
English (en)
Inventor
John A T Young
Kenneth A Bradley
Robert J Collier
Jeremy S Mogridge
Original Assignee
Wisconsin Alumni Res Found
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found, Harvard College filed Critical Wisconsin Alumni Res Found
Application granted granted Critical
Publication of ATE360071T1 publication Critical patent/ATE360071T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
AT01986969T 2000-12-05 2001-10-03 Rezeptor für ein toxin aus bacillus anthracis ATE360071T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25148100P 2000-12-05 2000-12-05

Publications (1)

Publication Number Publication Date
ATE360071T1 true ATE360071T1 (de) 2007-05-15

Family

ID=22952145

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01986969T ATE360071T1 (de) 2000-12-05 2001-10-03 Rezeptor für ein toxin aus bacillus anthracis

Country Status (6)

Country Link
US (4) US7074913B2 (de)
EP (1) EP1395657B1 (de)
AT (1) ATE360071T1 (de)
AU (1) AU2002239229A1 (de)
DE (1) DE60128008T2 (de)
WO (1) WO2002046228A2 (de)

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US6455673B1 (en) * 1994-06-08 2002-09-24 President And Fellows Of Harvard College Multi-mutant diphtheria toxin vaccines
US6808709B1 (en) * 1994-12-30 2004-10-26 The Regents Of The University Of California Immunoglobulins containing protection proteins and their use
CA2407426A1 (en) * 2000-04-28 2001-11-08 Planet Biotechnology, Inc. Immunoadhesin for the prevention of rhinovirus infection
US20020168367A1 (en) * 2000-04-28 2002-11-14 Planet Biotechnology Incorporated Novel immunoadhesins for treating and preventing viral and bacterial diseases
US20060015969A1 (en) * 2000-04-28 2006-01-19 Planet Biotechnology, Inc. Novel immunoadhesins for treating and prventing toxicity and pathogen-mediated diseases
JP2004527210A (ja) * 2000-08-02 2004-09-09 ザ ジョンズ ホプキンス ユニバーシティー 内皮細胞発現パターンの評価法
WO2002046228A2 (en) * 2000-12-05 2002-06-13 Wisconsin Alumni Research Foundation Receptor for b. anthracis toxin
US20070118934A1 (en) * 2001-10-26 2007-05-24 Planet Biotechnology, Inc. Chimeric toxin receptor proteins and chimeric toxin receptor proteins for treatment and prevention of anthrax
US20030144193A1 (en) * 2001-12-20 2003-07-31 Rottman James B. TANGO 197 and TANGO 216 compositions and methods
US7601351B1 (en) 2002-06-26 2009-10-13 Human Genome Sciences, Inc. Antibodies against protective antigen
WO2004052277A2 (en) * 2002-12-05 2004-06-24 Wisconsin Alumni Research Foundation Anthrax antitoxins
GB0423974D0 (en) 2004-10-28 2004-12-01 Ares Trading Sa Proteins
US7838252B2 (en) * 2005-02-17 2010-11-23 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating a subject having an anthrax toxin mediated condition
ITRM20060337A1 (it) * 2006-06-27 2007-12-28 Biosoot Srl Gene tem8 (tumor endotelial marker 8) e sue forme di espressione ed usi diagnostici e terapeutici
WO2008127302A2 (en) * 2006-10-27 2008-10-23 Genyous BioMed International, Inc. Compositions for treatment and inhibition of pain
TW201425333A (zh) * 2007-04-11 2014-07-01 Oncotherapy Science Inc 腫瘤血管內皮標誌８胜肽及包含此胜肽之疫苗
US7935345B2 (en) 2007-05-21 2011-05-03 Children's Hospital & Research Center At Oakland Monoclonal antibodies that specifically bind to and neutralize bacillus anthracis toxin, compositions, and methods of use
WO2012172495A1 (en) * 2011-06-14 2012-12-20 Novartis Ag Compositions and methods for antibodies targeting tem8
CA2837892A1 (en) 2011-06-14 2012-12-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Tem8 antibodies, conjugates thereof, and their use
CN105813654B (zh) 2013-10-11 2019-05-31 美国政府(由卫生和人类服务部的部长所代表) Tem8抗体及其用途
US10717927B2 (en) 2016-07-14 2020-07-21 Samsung Electronics Co., Ltd. Indium-based quantum dots and production methods thereof

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Publication number Priority date Publication date Assignee Title
US5604201A (en) * 1993-01-08 1997-02-18 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non-Profit Organization Methods and reagents for inhibiting furin endoprotease
US5591631A (en) * 1993-02-12 1997-01-07 The United States Of America As Represented By The Department Of Health And Human Services Anthrax toxin fusion proteins, nucleic acid encoding same
US5677274A (en) * 1993-02-12 1997-10-14 The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services Anthrax toxin fusion proteins and related methods
EP0866718A1 (de) * 1995-12-13 1998-09-30 President And Fellows Of Harvard College Verwendung von toxinpeptiden und/oder affinitätsgriffen zur einführung von verbindungen in zellen
US6592872B1 (en) * 1996-09-17 2003-07-15 The United States Of America As Represented By The Department Of Health And Human Services Targeting antigens to the MHC class I processing pathway with an anthrax toxin fusion protein
US7411051B2 (en) * 1997-03-07 2008-08-12 Human Genome Sciences, Inc. Antibodies to HDPPA04 polypeptide
US7368531B2 (en) * 1997-03-07 2008-05-06 Human Genome Sciences, Inc. Human secreted proteins
AU752833B2 (en) * 1998-04-01 2002-10-03 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Anthrax lethal factor is a MAPK kinase protease
US7175679B2 (en) * 2001-03-29 2007-02-13 Biotempt B.V. Oligopeptide treatment of NF-κB mediated inflammation
EP1155117A4 (de) 1998-12-30 2003-05-14 Millennium Pharm Inc Sekretierte proteine und nukleinsäuren die diese kodieren
US6329156B1 (en) * 1999-03-22 2001-12-11 The Regents Of The University Of California Method for screening inhibitors of the toxicity of Bacillus anthracis
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EP1244687A4 (de) * 1999-12-22 2005-06-15 Univ Ohio State Res Found Schutzma nahmen gegen die tödliche infektion durch i bacillus anthracis
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US6569662B1 (en) * 2000-01-21 2003-05-27 Hyseq, Inc. Nucleic acids and polypeptides
EP2213743A1 (de) * 2000-04-12 2010-08-04 Human Genome Sciences, Inc. Albuminfusionsproteine
EP1278764A4 (de) * 2000-05-04 2004-05-19 Harvard College Verbindungen und methoden zur behandlung und vorbeugung bakterieller infektionen(14.11.01)
JP2004527210A (ja) * 2000-08-02 2004-09-09 ザ ジョンズ ホプキンス ユニバーシティー 内皮細胞発現パターンの評価法
WO2002046228A2 (en) * 2000-12-05 2002-06-13 Wisconsin Alumni Research Foundation Receptor for b. anthracis toxin
JP2004533825A (ja) * 2001-04-11 2004-11-11 ザ ジョンズ ホプキンス ユニバーシティ 内皮細胞発現パターンの評価法
US20060084794A1 (en) * 2001-04-12 2006-04-20 Human Genome Sciences, Inc. Albumin fusion proteins
US20030108556A1 (en) * 2001-06-08 2003-06-12 Mekalanos John J. Therapeutic uses of polyvalent compositions in infectious diseases
US7176278B2 (en) * 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
US20070118934A1 (en) * 2001-10-26 2007-05-24 Planet Biotechnology, Inc. Chimeric toxin receptor proteins and chimeric toxin receptor proteins for treatment and prevention of anthrax
GB0126266D0 (en) * 2001-11-01 2002-01-02 Microbiological Res Authority Anthrax antigenic compositions
AU2002357747A1 (en) * 2001-12-10 2003-06-23 Millennium Pharmaceuticals Inc. Novel genes encoding colon cancer antigens
US20040258699A1 (en) * 2002-02-11 2004-12-23 Bowdish Katherine S. Immunotherapeutics for biodefense
WO2004052277A2 (en) * 2002-12-05 2004-06-24 Wisconsin Alumni Research Foundation Anthrax antitoxins
AU2003900747A0 (en) * 2003-02-18 2003-03-06 Garvan Institute Of Medical Research Diagnosis and treatment of pancreatic cancer
WO2005005598A2 (en) * 2003-04-11 2005-01-20 New York University B. anthracis luxs and furanone inhibition of a1-2 quorum sensing
EP1633785B1 (de) * 2003-05-21 2012-11-28 Medarex, Inc. Humane monoklonale antikörper gegen protektives antigen von bacillus anthracis
US20060246079A1 (en) * 2003-11-14 2006-11-02 Morrow Phillip R Neutralizing human antibodies to anthrax toxin
WO2005081749A2 (en) * 2004-01-23 2005-09-09 Avanir Pharmaceuticals, Inc. Neutralizing human antibodies to anthraxtoxin
ES2376337T3 (es) * 2004-03-03 2012-03-13 Iq Therapeutics Bv Anticuerpos monoclonales neutralizantes de la toxina del �?ntrax humanos y métodos para su uso.
US7588912B2 (en) * 2004-10-12 2009-09-15 Regents Of The University Of California Compositions and methods for preventing and treating anthrax diseases

Also Published As

Publication number Publication date
WO2002046228A2 (en) 2002-06-13
AU2002239229A1 (en) 2002-06-18
EP1395657A2 (de) 2004-03-10
US20050196407A1 (en) 2005-09-08
US7435418B2 (en) 2008-10-14
US20060083746A1 (en) 2006-04-20
US7074913B2 (en) 2006-07-11
US20070117159A1 (en) 2007-05-24
US20060110801A1 (en) 2006-05-25
EP1395657B1 (de) 2007-04-18
DE60128008T2 (de) 2008-01-10
DE60128008D1 (en) 2007-05-31
WO2002046228A3 (en) 2003-12-24

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