ATE360084T1 - Verfahren zum herstellen von dicarbonsäuren - Google Patents

Verfahren zum herstellen von dicarbonsäuren

Info

Publication number
ATE360084T1
ATE360084T1 AT98903871T AT98903871T ATE360084T1 AT E360084 T1 ATE360084 T1 AT E360084T1 AT 98903871 T AT98903871 T AT 98903871T AT 98903871 T AT98903871 T AT 98903871T AT E360084 T1 ATE360084 T1 AT E360084T1
Authority
AT
Austria
Prior art keywords
organism
carbon source
producing
maintain
medium
Prior art date
Application number
AT98903871T
Other languages
English (en)
Inventor
Nhuan Phu Nghiem
Mark Donnelly
Cynthia S Millard
Lucy Stols
Original Assignee
Ut Battelle Llc
Uchicago Argonne Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ut Battelle Llc, Uchicago Argonne Llc filed Critical Ut Battelle Llc
Application granted granted Critical
Publication of ATE360084T1 publication Critical patent/ATE360084T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT98903871T 1997-01-31 1998-01-30 Verfahren zum herstellen von dicarbonsäuren ATE360084T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/792,655 US5869301A (en) 1995-11-02 1997-01-31 Method for the production of dicarboxylic acids

Publications (1)

Publication Number Publication Date
ATE360084T1 true ATE360084T1 (de) 2007-05-15

Family

ID=25157624

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98903871T ATE360084T1 (de) 1997-01-31 1998-01-30 Verfahren zum herstellen von dicarbonsäuren

Country Status (14)

Country Link
US (1) US5869301A (de)
EP (1) EP1012323B1 (de)
JP (1) JP3681404B2 (de)
CN (1) CN1121500C (de)
AT (1) ATE360084T1 (de)
AU (1) AU724274B2 (de)
BR (1) BR9806822B1 (de)
CA (1) CA2278892C (de)
DE (1) DE69837607T2 (de)
DK (1) DK1012323T3 (de)
ES (1) ES2285757T3 (de)
HU (1) HU227509B1 (de)
PT (1) PT1012323E (de)
WO (1) WO1998033930A1 (de)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10129711B4 (de) * 2001-06-22 2007-08-23 Forschungszentrum Jülich GmbH Verfahren zur fermentativen Herstellung von Pyruvat
EP1575548B1 (de) 2002-05-04 2011-03-09 Acorda Therapeutics, Inc. Zusammensetzungen und verfahren zur förderung des neuronalen wachstums
DE10220234B4 (de) * 2002-05-06 2013-05-23 Forschungszentrum Jülich GmbH Verfahren sowie Mikroorganismen zur mikrobiellen Herstellung von Pyruvat aus Kohlenhydraten sowie Alkoholen
DE60337009D1 (de) * 2002-08-15 2011-06-16 Acorda Therapeutics Inc Chimärisches protein
EP3211084B1 (de) 2003-05-16 2019-03-27 Acorda Therapeutics, Inc. Proteoglycan-abbauende mutanten zur behandlung des zns
MXPA05012305A (es) * 2003-05-16 2006-04-18 Acorda Therapeutics Inc Composiciones y metodos para el tratamiento de lesiones del snc.
US7959914B2 (en) 2003-05-16 2011-06-14 Acorda Therapeutics, Inc. Methods of reducing extravasation of inflammatory cells
JP4469568B2 (ja) * 2003-07-09 2010-05-26 三菱化学株式会社 有機酸の製造方法
DK1647594T3 (da) * 2003-07-29 2010-05-25 Res Inst Innovative Tech Earth Koryneform bakteriel transformant og fremgangsmåde til fremstilling af dicarboxylsyre under anvendelse af denne
BRPI0413403A (pt) * 2003-08-28 2006-10-17 Mitsubishi Chem Corp método para produzir ácido succìnico
EP1672067B1 (de) * 2003-09-17 2015-11-11 Mitsubishi Chemical Corporation Verfahren zur herstellung einer organischen nicht-amino-säure
CN100534972C (zh) * 2003-09-30 2009-09-02 味之素株式会社 从发酵液中纯化琥珀酸的方法
JP2005295998A (ja) * 2003-11-07 2005-10-27 Mitsubishi Chemicals Corp 有機酸アンモニウム溶液の製造方法
BRPI0416274A (pt) * 2003-11-07 2007-01-09 Mitsubishi Chemical Corp E Aji método para produzir solução de amÈnio de ácido orgánico
AU2005244933B2 (en) * 2004-05-18 2011-08-04 Acorda Therapeutics, Inc. Methods of purifying chondroitinase and stable formulations thereof
CN1989239B (zh) * 2004-05-20 2013-07-10 味之素株式会社 生产琥珀酸的细菌和生产琥珀酸的方法
BRPI0510919A (pt) * 2004-05-20 2008-05-20 Ajinomoto Kk bactéria produtora de ácido succìnico e processo para produzir ácido succìnico
EP3130676A1 (de) 2004-08-27 2017-02-15 Rice University Mutanter e. coli-stamm mit erhöhter bernsteinsäureproduktion
WO2006034156A2 (en) * 2004-09-17 2006-03-30 Rice University High succinate producing bacteria
JP4537862B2 (ja) * 2005-01-18 2010-09-08 財団法人地球環境産業技術研究機構 好気性細菌による高効率な有機酸の製造方法
EP3919543A3 (de) * 2005-04-22 2022-03-16 Mitsubishi Chemical Corporation Aus einer biomassenressource gewonnenes polyester und herstellungsverfahren dafür
JP4380654B2 (ja) * 2005-04-22 2009-12-09 三菱化学株式会社 ポリエステル及びその製造方法
JP4380653B2 (ja) * 2005-04-22 2009-12-09 三菱化学株式会社 ポリエステル及びその製造方法
CN101300356A (zh) * 2005-09-09 2008-11-05 基因组股份公司 用于琥珀酸盐之生长关联性生产的方法和生物
JP5189985B2 (ja) 2005-09-26 2013-04-24 アコーダ セラピューティクス、インク. コンドロイチナーゼabci変異体を用いた組成物およびその使用方法
EP1947190B1 (de) * 2005-10-18 2017-11-29 Ajinomoto Co., Inc. Verfahren zur herstellung von bernsteinsäure
US7335066B2 (en) * 2005-12-16 2008-02-26 James A. Carroll Network connector and connection system
WO2007099867A1 (ja) * 2006-02-24 2007-09-07 Mitsubishi Chemical Corporation 有機酸生産菌及び有機酸の製造法
EP1842843A1 (de) * 2006-04-04 2007-10-10 Basf Aktiengesellschaft Verfahren zur Herstellung eines Carbonsäurealkylesters
CN101517086A (zh) 2006-07-21 2009-08-26 希乐克公司 生物质转化系统
AU2007307736C1 (en) 2006-10-10 2014-04-10 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase ABCI mutants
US8673601B2 (en) * 2007-01-22 2014-03-18 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
TWI568847B (zh) 2007-03-16 2017-02-01 奇諾麥提卡公司 用於1,4-丁二醇及其前驅物之生物合成的組合物及方法
US8691539B2 (en) 2007-03-20 2014-04-08 University Of Florida Research Foundation, Inc. Materials and methods for efficient succinate and malate production
DE102007019184A1 (de) * 2007-04-20 2008-10-23 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
MX298012B (es) 2007-07-06 2012-11-04 Basf Se Metodo para la produccion de una solucion de glucosa acuosa a partir de maiz.
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
TWI525195B (zh) 2007-08-10 2016-03-11 奇諾麥提卡公司 合成烯酸及其衍生物之方法
US8735112B2 (en) * 2007-11-20 2014-05-27 Dsm Ip Assets B.V. Dicarboxylic acid production in a recombinant yeast
FR2925068B1 (fr) * 2007-12-13 2010-01-08 Roquette Freres Procedes de production d'acide succinique
US8486686B2 (en) * 2007-12-28 2013-07-16 William Marsh Rice University Large scale microbial culture method
US7803589B2 (en) 2008-01-22 2010-09-28 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
SI2262901T1 (sl) 2008-03-05 2019-02-28 Genomatica, Inc. Primarni alkohol producirajoči organizmi
EP3351619A1 (de) 2008-03-27 2018-07-25 Genomatica, Inc. Mikroorganismen zur herstellung von adipinsäure und anderen verbindungen
EP2285973A4 (de) 2008-05-01 2012-04-25 Genomatica Inc Verfahren zur herstellung von methacrylsäure
EP2304039B1 (de) * 2008-06-17 2019-08-21 Genomatica, Inc. Mikroorganismen und verfahren zur biosynthese von fumarat, malat und acrylat
US9012187B2 (en) 2008-07-08 2015-04-21 Dsm Ip Assets B.V. Dicarboxylic acid production by fermentation at low pH
US20100021978A1 (en) * 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
CA2735883C (en) * 2008-09-10 2020-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
DE102008051727A1 (de) 2008-10-17 2010-04-22 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
WO2010057022A1 (en) * 2008-11-14 2010-05-20 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
KR20110097951A (ko) * 2008-12-16 2011-08-31 게노마티카 인코포레이티드 합성가스와 다른 탄소원을 유용 제품으로 전환시키기 위한 미생물 및 방법
FR2941959B1 (fr) * 2009-02-12 2013-06-07 Roquette Freres Procedes de production d'acide succinique
EP2414505B1 (de) 2009-04-02 2019-05-22 University of Florida Research Foundation, Inc. Manipulation eines weges zur succinatherstellung
AU2010242849A1 (en) 2009-04-30 2011-11-24 Genomatica, Inc. Organisms for the production of isopropanol, n-butanol, and isobutanol
KR102115497B1 (ko) * 2009-04-30 2020-05-26 게노마티카 인코포레이티드 1,3-부탄다이올 생산 유기체
KR20200038334A (ko) 2009-05-07 2020-04-10 게노마티카 인코포레이티드 아디페이트, 헥사메틸렌디아민 및 6-아미노카프로산의 생합성을 위한 미생물 및 방법
EP2429587A4 (de) * 2009-05-15 2014-10-08 Genomatica Inc Organismen zur herstellung von cyclohexanon
US8129169B2 (en) 2009-06-04 2012-03-06 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
KR20180042467A (ko) * 2009-06-04 2018-04-25 게노마티카 인코포레이티드 발효액 성분들의 분리 방법
JP2012529889A (ja) * 2009-06-10 2012-11-29 ゲノマチカ, インク. Mek及び2−ブタノールの炭素効率のよい生合成のための微生物及び方法
WO2011017560A1 (en) 2009-08-05 2011-02-10 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
PL2470667T3 (pl) * 2009-08-27 2018-04-30 Dsm Ip Assets B.V. Sposób wytwarzania kwasu dikarboksylowego na drodze fermentacji
EP2475775A4 (de) 2009-09-09 2013-03-20 Genomatica Inc Mikroorganismen und verfahren zur gleichzeitigen herstellung von isopropanol und primären alkoholen, diolen und säuren
WO2011047101A1 (en) * 2009-10-13 2011-04-21 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto
KR20120088753A (ko) 2009-10-23 2012-08-08 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
WO2011066076A1 (en) 2009-11-25 2011-06-03 Genomatica, Inc. Microorganisms and methods for the coproduction of 1,4-butanediol and gamma-butyrolactone
CA2783096A1 (en) 2009-12-10 2011-06-16 Genomatica, Inc. Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol
BR112012018620A2 (pt) * 2010-01-29 2015-09-15 Genomatica Inc organismo microbiano de ocorrência não-natural, método para produzir (2-hidroxi-3-metil-4-oxobutoxi) fosfonato, método para produção de p-toluato, método para produzir tereftalato
US8445244B2 (en) * 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
JP5911847B2 (ja) 2010-05-05 2016-04-27 ジェノマティカ, インコーポレイテッド ブタジエンの生合成のための微生物および方法
US20110306734A1 (en) 2010-06-02 2011-12-15 Bayer Materialscience Ag Thermoplastically processable polyurethanes based on succinic acid propionates
KR101918201B1 (ko) 2010-06-08 2019-02-08 오리건 스테이트 유니버시티 식물성 기름-기초 압력 민감성 접착제
SG187174A1 (en) 2010-07-26 2013-02-28 Genomatica Inc Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
WO2012125218A1 (en) 2011-03-14 2012-09-20 Dow Global Technologies Llc Processes for producing terephthalic acid and terephthalic esters
CN102242074B (zh) * 2011-04-12 2014-08-06 叶春 一种兼性厌氧菌的筛选方法
US8580096B2 (en) 2011-09-29 2013-11-12 Uchicago Argonne, Llc Bioprocess utilizing carbon dioxide and electrodeionization
EP2760902B1 (de) 2011-09-30 2018-08-08 Covestro Deutschland AG Homogene extrudierte artikel aus thermoplastisch verarbeitbaren polyurethanen auf basis von polyesterdiolen aus bernsteinsäure und 1,3 -propandiol
WO2013154610A1 (en) 2012-04-09 2013-10-17 Avery Dennison Corporation Pressure sensitive adhesives based on renewable resources, uv curing and related methods
US9234012B2 (en) 2012-04-30 2016-01-12 Woods Hole Oceanographic Institution Cobalamin acquisition protein and use thereof
SI2855687T1 (sl) 2012-06-04 2020-09-30 Genomatica, Inc. Mikroorganizmi in metode za proizvodnjo 4-hidroksibutirat, 1,4-butandiola in sorodne spojine
WO2017192925A1 (en) * 2016-05-05 2017-11-09 William Marsh Rice University Improved microbial production of fats
CN113316624A (zh) 2018-11-20 2021-08-27 俄勒冈州立大学 来自植物油或动物脂的紫外线辐射固化的压敏粘合剂
SG11202112865YA (en) 2019-05-31 2021-12-30 Univ Oregon State Pressure sensitive adhesives made from uv curing of plant oil-based polyesters
CN110951660B (zh) * 2019-12-19 2021-12-03 江南大学 一株固定co2产苹果酸的大肠杆菌工程菌的构建及应用
CN114350718B (zh) * 2021-12-31 2024-06-07 安徽丰原发酵技术工程研究有限公司 一种发酵生产苹果酸的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5543759B2 (de) * 1972-06-28 1980-11-07
US4190495A (en) * 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
JPS60114197A (ja) * 1983-11-25 1985-06-20 Agency Of Ind Science & Technol 微生物によるジカルボン酸の製造法
US4871667A (en) * 1984-11-26 1989-10-03 Agency Of Industrial Science & Technology Process for preparing muconic acid
US5168055A (en) * 1986-06-11 1992-12-01 Rathin Datta Fermentation and purification process for succinic acid
DE3783081T2 (de) * 1986-06-11 1993-04-15 Michigan Biotech Inst Verfahren zur herstellung von bernsteinsaeure durch anaerobe fermentation.
US5143834A (en) * 1986-06-11 1992-09-01 Glassner David A Process for the production and purification of succinic acid
US5182199A (en) * 1987-05-27 1993-01-26 Hartley Brian S Thermophilic ethanol production in a two-stage closed system
CA2062753C (en) * 1989-04-27 2005-04-26 N. Robert Ward, Jr. Precipitate test for microorganisms
US5416020A (en) * 1992-09-29 1995-05-16 Bio-Technical Resources Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid
FR2702492B1 (fr) * 1993-03-12 1995-05-24 Rhone Poulenc Chimie Procédé de production par fermentation d'acide itaconique.
BR9407269A (pt) * 1993-06-25 1996-10-01 Du Pont Processo de preparação de ácido pirúvico
CA2166381C (en) * 1993-07-01 2005-05-24 David Leroy Anton An improved method of preparing glyoxylic acid/aminomethylphosphonic acid mixtures using a microbial double-transformant
US5521075A (en) * 1994-12-19 1996-05-28 Michigan Biotechnology Institute Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
US5504004A (en) * 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms

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CA2278892C (en) 2009-02-24
CN1121500C (zh) 2003-09-17
EP1012323A1 (de) 2000-06-28
DE69837607D1 (de) 2007-05-31
DK1012323T3 (da) 2007-06-18
WO1998033930A1 (en) 1998-08-06
ES2285757T3 (es) 2007-11-16
BR9806822B1 (pt) 2009-05-05
CA2278892A1 (en) 1998-08-06
EP1012323A4 (de) 2002-01-16
BR9806822A (pt) 2000-05-09
HUP0001997A2 (hu) 2000-10-28
AU6052398A (en) 1998-08-25
US5869301A (en) 1999-02-09
EP1012323B1 (de) 2007-04-18
HUP0001997A3 (en) 2002-01-28
HU227509B1 (en) 2011-07-28
DE69837607T2 (de) 2007-12-27
PT1012323E (pt) 2007-05-31
CN1246155A (zh) 2000-03-01
AU724274B2 (en) 2000-09-14
JP2000515389A (ja) 2000-11-21
JP3681404B2 (ja) 2005-08-10

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