DK1689461T5 - Anvendelse af en hydrogel til dyrkning af chondrocytter - Google Patents

Anvendelse af en hydrogel til dyrkning af chondrocytter

Info

Publication number: DK1689461T5
Authority: DK; Denmark
Prior art keywords: chondrocytes; hydrogel; silanated; complex; dimensional culture
Prior art date: 2003-11-04

Application number

DK04805394T

Other languages

English (en)

Other versions

DK1689461T3 (da

Inventor

Pierre Weiss

Jerome Guicheux

Pierre Daculsi

Gael Grimandi

Claire Vinatier

Original Assignee

Inst Nat Sante Rech Med

Univ Nantes

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-11-04

Filing date

2004-11-04

Publication date

2007-10-15

2004-11-04 Application filed by Inst Nat Sante Rech Med, Univ Nantes filed Critical Inst Nat Sante Rech Med

2007-09-10 Publication of DK1689461T3 publication Critical patent/DK1689461T3/da

2007-10-15 Application granted granted Critical

2007-10-15 Publication of DK1689461T5 publication Critical patent/DK1689461T5/da

Links

210000001612 chondrocyte Anatomy 0.000 title abstract 4
239000000017 hydrogel Substances 0.000 title abstract 2
229920000663 Hydroxyethyl cellulose Polymers 0.000 abstract 2
239000004354 Hydroxyethyl cellulose Substances 0.000 abstract 2
235000019447 hydroxyethyl cellulose Nutrition 0.000 abstract 2
239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 2
229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 2
235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 2
UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 2
239000006177 biological buffer Substances 0.000 abstract 1
210000000845 cartilage Anatomy 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
238000004132 cross linking Methods 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1
230000010354 integration Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3852—Cartilage, e.g. meniscus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Zoology (AREA)
Cell Biology (AREA)
General Health & Medical Sciences (AREA)
Rheumatology (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Transplantation (AREA)
Oral & Maxillofacial Surgery (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Dermatology (AREA)
Botany (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Organic Chemistry (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Urology & Nephrology (AREA)
General Engineering & Computer Science (AREA)
Vascular Medicine (AREA)
Developmental Biology & Embryology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Materials For Medical Uses (AREA)
Compositions Of Macromolecular Compounds (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

DK04805394T 2003-11-04 2004-11-04 Anvendelse af en hydrogel til dyrkning af chondrocytter DK1689461T5 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP03292759A EP1529543A1 (fr)	2003-11-04	2003-11-04	Utilisation d'un hydrogel pour la culture de chondrocytes
PCT/FR2004/002844 WO2005044326A1 (fr)	2003-11-04	2004-11-04	Utilisation d'un hydrogel pour la culture de chondrocytes.

Publications (2)

Publication Number	Publication Date
DK1689461T3 DK1689461T3 (da)	2007-09-10
DK1689461T5 true DK1689461T5 (da)	2007-10-15

Family

ID=34429548

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04805394T DK1689461T5 (da)	2003-11-04	2004-11-04	Anvendelse af en hydrogel til dyrkning af chondrocytter

Country Status (12)

Country	Link
US (2)	US20070212389A1 (da)
EP (2)	EP1529543A1 (da)
JP (1)	JP4351258B2 (da)
CN (1)	CN100509064C (da)
AT (1)	ATE361108T1 (da)
AU (1)	AU2004287234B2 (da)
CA (1)	CA2543917A1 (da)
DE (1)	DE602004006299T2 (da)
DK (1)	DK1689461T5 (da)
ES (1)	ES2286709T3 (da)
PL (1)	PL1689461T3 (da)
WO (1)	WO2005044326A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7622562B2 (en)	2002-06-26	2009-11-24	Zimmer Orthobiologics, Inc.	Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
ES2396689T3 (es)	2003-12-11	2013-02-25	Isto Technologies Inc.	Sistema de cartílago particulado
EP1916964A4 (en)	2005-08-26	2015-11-04	Zimmer Inc	IMPLANTS AND METHODS FOR THE REPAIR, REPLACEMENT AND TREATMENT OF JOINT DISEASES
EP1764117A1 (en) *	2005-09-20	2007-03-21	Zimmer GmbH	Implant for the repair of a cartilage defect and method for manufacturing the implant
US8163549B2 (en)	2006-12-20	2012-04-24	Zimmer Orthobiologics, Inc.	Method of obtaining viable small tissue particles and use for tissue repair
AU2008240191B2 (en)	2007-04-12	2013-09-19	Zimmer, Inc.	Compositions and methods for tissue repair
US10010649B2 (en) *	2007-05-04	2018-07-03	Ascendia Ab	Method and means for culturing osteoblastic cells
WO2009057755A1 (ja) *	2007-11-02	2009-05-07	National Institute Of Advanced Industrial Science And Technology	糖鎖アレイ基板とそれを用いた糖鎖結合分子検出法
JP5544635B2 (ja) *	2009-09-30	2014-07-09	国立大学法人北海道大学	軟骨細胞再分化誘導用基材およびこれを用いた軟骨細胞の製造方法
US9414930B2 (en) *	2010-10-26	2016-08-16	Kyphon SÀRL	Activatable devices containing a chemonucleolysis agent
EP2714891B1 (en)	2011-06-03	2019-11-13	Institut National de la Sante et de la Recherche Medicale (INSERM)	Silylated biomolecule-based hydrogel for culturing cardiomyocytes and stem cells, and use of the hydrogel thereof for treating heart failure
CN102775831B (zh) *	2012-07-31	2014-11-12	华南理工大学	在材料表面紫外表固化接枝两性离子凝胶涂层的方法
US20140178343A1 (en)	2012-12-21	2014-06-26	Jian Q. Yao	Supports and methods for promoting integration of cartilage tissue explants
WO2015084972A1 (en) *	2013-12-03	2015-06-11	Cornell University	Method of repairing an annulus and collagen gel composition
WO2016081742A1 (en) *	2014-11-19	2016-05-26	The Trustees Of Columbia University In The City Of New York	Systems, methods, and devices for cell cycle synchronization of stem cells
EP3167911A1 (en) *	2015-11-10	2017-05-17	Oniris	Si-hpmc-encapsulated insulin-producing cells for the treatment of type 1 diabetes
CN108102129B (zh) *	2016-11-25	2021-01-01	山西加乐医疗科技有限责任公司	一种纤维素海绵的制备方法
CN108042567A (zh) *	2017-12-15	2018-05-18	广州金塞迩中西医结合医院有限公司	用于软骨修复的生物组合制剂及其应用
CN109172604A (zh) *	2018-08-08	2019-01-11	浙江大学	一种msc水凝胶复合物及应用
WO2020209316A1 (ja) *	2019-04-08	2020-10-15	有限会社ジーエヌコーポレーション	組織再生能が高い軟骨細胞培養物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5902741A (en) *	1986-04-18	1999-05-11	Advanced Tissue Sciences, Inc.	Three-dimensional cartilage cultures
US5709854A (en) *	1993-04-30	1998-01-20	Massachusetts Institute Of Technology	Tissue formation by injecting a cell-polymeric solution that gels in vivo
US6129761A (en) *	1995-06-07	2000-10-10	Reprogenesis, Inc.	Injectable hydrogel compositions
FR2737663B1 (fr) *	1995-08-07	1997-10-03	Centre Nat Rech Scient	Composition pour bio-materiau, procede de preparation
FR2798671A1 (fr) *	1999-09-16	2001-03-23	Univ Paris Curie	Compositions de chondrocytes, preparation et utilisations

2003
- 2003-11-04 EP EP03292759A patent/EP1529543A1/fr not_active Withdrawn
2004
- 2004-11-04 EP EP04805394A patent/EP1689461B9/fr not_active Expired - Lifetime
- 2004-11-04 ES ES04805394T patent/ES2286709T3/es not_active Expired - Lifetime
- 2004-11-04 JP JP2006537372A patent/JP4351258B2/ja not_active Expired - Fee Related
- 2004-11-04 AU AU2004287234A patent/AU2004287234B2/en not_active Ceased
- 2004-11-04 US US10/577,942 patent/US20070212389A1/en not_active Abandoned
- 2004-11-04 CA CA002543917A patent/CA2543917A1/fr not_active Abandoned
- 2004-11-04 CN CNB2004800383605A patent/CN100509064C/zh not_active Expired - Fee Related
- 2004-11-04 AT AT04805394T patent/ATE361108T1/de active
- 2004-11-04 DK DK04805394T patent/DK1689461T5/da active
- 2004-11-04 PL PL04805394T patent/PL1689461T3/pl unknown
- 2004-11-04 DE DE602004006299T patent/DE602004006299T2/de not_active Expired - Lifetime
- 2004-11-04 WO PCT/FR2004/002844 patent/WO2005044326A1/fr not_active Ceased
2010
- 2010-05-24 US US12/785,874 patent/US8440462B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US8440462B2 (en)	2013-05-14
DK1689461T3 (da)	2007-09-10
CA2543917A1 (fr)	2005-05-19
JP2007510410A (ja)	2007-04-26
DE602004006299T2 (de)	2008-04-10
JP4351258B2 (ja)	2009-10-28
EP1689461B9 (fr)	2007-08-29
EP1689461A1 (fr)	2006-08-16
ATE361108T1 (de)	2007-05-15
AU2004287234A1 (en)	2005-05-19
ES2286709T3 (es)	2007-12-01
EP1689461B1 (fr)	2007-05-02
DE602004006299D1 (de)	2007-06-14
EP1529543A1 (fr)	2005-05-11
WO2005044326A1 (fr)	2005-05-19
US20100297764A1 (en)	2010-11-25
AU2004287234B2 (en)	2010-08-05
CN1897989A (zh)	2007-01-17
CN100509064C (zh)	2009-07-08
PL1689461T3 (pl)	2007-10-31
US20070212389A1 (en)	2007-09-13

Publication	Publication Date	Title
DK1689461T5 (da)	2007-10-15	Anvendelse af en hydrogel til dyrkning af chondrocytter
DE602004008453D1 (de)	2007-10-04	Künstliches immunorgan
BR0210599A (pt)	2004-07-20	Uso de monóxido de carbono, método para manutenção de uma célula animal in vitro, artigo de manufatura, bem como meio celular estéril
SE0201328L (sv)	2002-07-05	Hematopoietisk differentiering av humana embryonala stamceller
GB0518898D0 (en)	2005-10-26	Porous matrix
WO2004096975A3 (en)	2005-03-10	Apparatus and methods for amplification of blood stem cell numbers
EP1788073A4 (en)	2011-10-26	POROUS BLEACHING ELEMENT FOR CELL CULTURES AND BIOREACTOR THEREWITH, AND CULTURING METHOD THEREFOR
CN1454100A (zh)	2003-11-05	组织再生用基材、移植用材料及其制法
EP1835023A4 (en)	2008-09-10	PRECIPITATING CELL DERIVED FROM HUMAN HORNHAIL ENTHELIAL CELLS, OR DERIVED CELL ASSOCIATION, METHOD FOR THE MANUFACTURE THEREOF, AND METHOD FOR TRANSPLANTING THE PRECURSOR CELL OR THE CELL ASSOCIATION
ATE460498T1 (de)	2010-03-15	Verfahren zur herstellung eines kapselpolysaccharids zur verwendung in konjugat- impfstoffen
EP3761031A4 (en)	2022-06-01	METHOD FOR ISOLATION OF CELL NUCLEARS WITH INCREASED ANTIGENICITY FROM IMMOBILIZED CELLS OR FFPE TISSUE SECTIONS, AND ANTIGEN ACTIVATOR AND KIT THEREFORE
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ATE521697T1 (de)	2011-09-15	Verfahren zum wachstum von menschlichen bindehautgewebeäquivalenten für die forschung, die klinische augenoberflächentransplantation und die geweberekonstruktion
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NO20061899L (no)	2006-06-28	Kunstig biologisk implantat og dets bruk og fremgangsmate for redusering av risikoen for dannelse av bindevev etter implantasjon
DE602005009978D1 (de)	2008-11-06	Verfahren zur herstellung von zwei- und dreidimensionalen polymergerüsten
DE60006552D1 (de)	2003-12-18	Verfahren zur herstellung von exopolysaccharide
ATE340250T1 (de)	2006-10-15	Verfahren zur kultivierung von zellen, membranmodul, verwendung eines membranmoduls und reaktionssystem zur kultivierung von zellen
ATE552018T1 (de)	2012-04-15	Matrix-gel-transplantat ohne zellen
CN106769298B (zh)	2019-04-16	一种植物组织的显微观察方法
CN101450227B (zh)	2012-10-24	一种中空管状支架材料的制备方法
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