ATE362481T1 - Lantibiotikum - Google Patents

Lantibiotikum

Info

Publication number: ATE362481T1
Authority: AT; Austria
Prior art keywords: salivaricin; lantibiotics; applications; bacteriocidal; pyogenes
Prior art date: 1999-10-12

Application number

AT00970338T

Other languages

English (en)

Inventor

John Tagg

Karen Dierksen

Mathew Upton

Original Assignee

Blis Technologies Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-12

Filing date

2000-10-12

Publication date

2007-06-15

2000-10-12 Application filed by Blis Technologies Ltd filed Critical Blis Technologies Ltd

2007-06-15 Application granted granted Critical

2007-06-15 Publication of ATE362481T1 publication Critical patent/ATE362481T1/de

Links

108010062877 Bacteriocins Proteins 0.000 title 1
WYCRECCWGWCUHS-KABIMGDMSA-N C([C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)CN)C(C)C)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(O)=O)C1=CN=CN1 Chemical compound C([C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)CN)C(C)C)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(O)=O)C1=CN=CN1 WYCRECCWGWCUHS-KABIMGDMSA-N 0.000 abstract 2
108700018795 salivaricin A Proteins 0.000 abstract 2
230000001225 therapeutic effect Effects 0.000 abstract 2
206010061372 Streptococcal infection Diseases 0.000 abstract 1
241000193996 Streptococcus pyogenes Species 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Pulmonology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Otolaryngology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Jellies, Jams, And Syrups (AREA)
Peptides Or Proteins (AREA)
Dairy Products (AREA)
Medicinal Preparation (AREA)
Confectionery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT00970338T 1999-10-12 2000-10-12 Lantibiotikum ATE362481T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NZ50026199		1999-10-12

Publications (1)

Publication Number	Publication Date
ATE362481T1 true ATE362481T1 (de)	2007-06-15

Family

ID=19927569

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00970338T ATE362481T1 (de)	1999-10-12	2000-10-12	Lantibiotikum

Country Status (15)

Country	Link
US (2)	US6773912B1 (de)
EP (1)	EP1169340B1 (de)
JP (1)	JP3673497B2 (de)
AT (1)	ATE362481T1 (de)
AU (1)	AU772224B2 (de)
BR (1)	BR0014740A (de)
CA (1)	CA2363713C (de)
DE (1)	DE60034879T8 (de)
DK (1)	DK1169340T3 (de)
ES (1)	ES2286038T3 (de)
HK (1)	HK1039622B (de)
NO (1)	NO326899B1 (de)
PL (1)	PL206441B1 (de)
RU (1)	RU2279481C2 (de)
WO (1)	WO2001027143A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1483366B1 (de) *	2002-02-22	2010-04-14	Blis Technologies Limited	Antimikrobielle zusammensetzung
US6861236B2 (en)	2002-05-24	2005-03-01	Applied Nanosystems B.V.	Export and modification of (poly)peptides in the lantibiotic way
WO2004072272A1 (en) *	2003-02-14	2004-08-26	Blis Technologies Limited	Bacterial compositions
DK1653982T3 (en) *	2003-07-18	2019-01-14	Blis Tech Limited	TREATMENT OF HALITOSIS
EP1730180A4 (de) *	2004-02-24	2008-06-18	Commw Scient Ind Res Org	Gegen pilze wirkende peptide
WO2007070518A2 (en) *	2005-12-13	2007-06-21	The Trustees Of The University Of Pennsylvania	Bacteria-derived blis for treatment of acne
FR2905268B1 (fr) *	2006-09-01	2009-01-23	Unither Dev Soc Par Actions Si	Substitut salivaire
RU2441915C9 (ru) *	2007-08-03	2012-06-20	Сентинелла Фармасьютикалс, Инк.	Гены и белки для биосинтеза лантибиотика 107891
GB0921995D0 (en) *	2009-12-17	2010-02-03	Univ Manchester	Antimicrobial peptides
ES2573729T3 (es) *	2010-04-07	2016-06-09	D.M.G. Italia Srl	Utilización del Streptococcus salivarius en el tratamiento de infecciones crónicas del tracto respiratorio
DE102012203547A1 (de) *	2012-03-07	2013-09-12	Robert Bosch Gesellschaft Für Medizinische Forschung Mbh	Antimikrobielle Peptide
CA2783414A1 (en) *	2012-07-22	2014-01-22	Integral Medical Inc.	Probiotic composition
CN104398537A (zh) *	2014-11-17	2015-03-11	南京灿辰微生物科技有限公司	一种口腔益生菌组合物
CN111227035A (zh) *	2018-11-28	2020-06-05	内蒙古伊利实业集团股份有限公司	一种含益生菌组合物的发酵乳及其制备方法
CN112391305B (zh) *	2019-08-15	2023-01-13	上海交通大学	唾液链球菌f286及其用途
WO2023053073A1 (en) *	2021-09-30	2023-04-06	Blis Technologies Limited	Probiotic enhancers and uses thereof
CN117304334A (zh) *	2023-04-25	2023-12-29	大连医科大学	一种唾液链球菌抗菌肽及其制备方法和应用
WO2025132965A1 (en)	2023-12-21	2025-06-26	Reichardt Elisabeth	Formulations and devices comprising lantibiotic-producing bacteria

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3925160A (en)	1974-09-26	1975-12-09	Univ Creighton	Method of producing an antibiotic
JPS615022A (ja) *	1984-06-19	1986-01-10	Advance Res & Dev Co Ltd	腸内細菌叢改善剤
SE463349B (sv)	1989-02-15	1990-11-12	Grahn Eva E	Farmaceutiskt preparat foer profylax mot och/eller behandling av beta-streptokockinducerad tonsillit
JPH054927A (ja) *	1991-06-28	1993-01-14	Aizo Matsushiro	乳酸菌含有組成物及びその製造方法
US5872001A (en)	1994-04-20	1999-02-16	Uab Research Foundation	Lanthionine antibiotic compositions and methods

2000
- 2000-10-12 PL PL364771A patent/PL206441B1/pl unknown
- 2000-10-12 WO PCT/NZ2000/000197 patent/WO2001027143A1/en not_active Ceased
- 2000-10-12 CA CA002363713A patent/CA2363713C/en not_active Expired - Lifetime
- 2000-10-12 US US09/913,763 patent/US6773912B1/en not_active Expired - Lifetime
- 2000-10-12 DE DE60034879T patent/DE60034879T8/de active Active
- 2000-10-12 AT AT00970338T patent/ATE362481T1/de not_active IP Right Cessation
- 2000-10-12 EP EP00970338A patent/EP1169340B1/de not_active Expired - Lifetime
- 2000-10-12 BR BR0014740-0A patent/BR0014740A/pt not_active Application Discontinuation
- 2000-10-12 AU AU79737/00A patent/AU772224B2/en not_active Expired
- 2000-10-12 JP JP2001530361A patent/JP3673497B2/ja not_active Expired - Fee Related
- 2000-10-12 HK HK02100947.2A patent/HK1039622B/en unknown
- 2000-10-12 ES ES00970338T patent/ES2286038T3/es not_active Expired - Lifetime
- 2000-10-12 DK DK00970338T patent/DK1169340T3/da active
- 2000-10-12 RU RU2002112327/13A patent/RU2279481C2/ru active
2001
- 2001-08-10 NO NO20013905A patent/NO326899B1/no not_active IP Right Cessation
2004
- 2004-05-19 US US10/848,750 patent/US20040232205A1/en not_active Abandoned

Also Published As

Publication number	Publication date
NO20013905D0 (no)	2001-08-10
US6773912B1 (en)	2004-08-10
JP3673497B2 (ja)	2005-07-20
NO326899B1 (no)	2009-03-16
JP2003516123A (ja)	2003-05-13
AU7973700A (en)	2001-04-23
ES2286038T3 (es)	2007-12-01
NO20013905L (no)	2001-10-10
DE60034879D1 (en)	2007-06-28
AU772224B2 (en)	2004-04-22
BR0014740A (pt)	2002-06-18
DE60034879T8 (de)	2008-07-03
CA2363713A1 (en)	2001-04-19
HK1039622A1 (en)	2002-05-03
CA2363713C (en)	2007-11-06
US20040232205A1 (en)	2004-11-25
PL364771A1 (en)	2004-12-13
EP1169340B1 (de)	2007-05-16
WO2001027143A1 (en)	2001-04-19
DE60034879T2 (de)	2008-02-07
DK1169340T3 (da)	2007-09-24
EP1169340A4 (de)	2005-06-08
PL206441B1 (pl)	2010-08-31
RU2279481C2 (ru)	2006-07-10
HK1039622B (en)	2007-10-18
EP1169340A1 (de)	2002-01-09

Legal Events

Date	Code	Title	Description
2007-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE362481T1 (de)	2007-06-15	Lantibiotikum
CY1110914T1 (el)	2014-02-12	Δικυκλο-πυραζολες δραστικες ως αναστολεις kinασων, διεργασια για την παρασκευη τους και φαρμακευτικες συνθεσεις που τις περιλαμβανουν
ZA200202306B (en)	2002-12-24	Topical treatment of streptococcal infections.
YU91603A (sh)	2006-08-17	Kristalni oblici azitromicina
DE60113851D1 (de)	2006-02-16	Bakteriophage mit breitem wirtspektrum
DE60226724D1 (de)	2008-07-03	Antimikrobielles polypeptid
CY1108610T1 (el)	2014-04-09	Πεπτιδια της il-2 και παραγωγα αυτων και χρηση αυτων ως θεραπευτικοι παραγοντες
TR200201484T2 (tr)	2003-02-21	Çeşitli hastalıkların koruyucu ve iyileştirici tedavisi için bakteriyel fajlar ile ilişkili lisleme enzimlerinin kullanımı
DE69435307D1 (de)	2010-09-16	Bazillus Thuringiensis und dessen insektizide Proteine
MA28613B1 (fr)	2007-06-01	Macrocycles d'amide antibacteriens
CY1106234T1 (el)	2011-06-08	Συνθεσεις για τη θepαπεια μολυνσεων staphylococcus aureus
BR9807523A (pt)	2000-03-21	Quinoxalinas em combinação tripla com inibidores da protease e inibidores de transcriptase reversa como medicamentos para o tratamento de aids.
DK1228097T3 (da)	2006-04-18	Antimikrobiel aktivitet af den förste kationiske humane lactoferrin-klynge
TR199900661T2 (xx)	1999-06-21	Cilt enfeksiyonlar�n�n tedavisi amac�yla 1-hidroksi-2-piridonlar�n kullan�m�
WO2000058475A3 (en)	2001-03-08	Streptococcus pneumoniae antigens
ATE259654T1 (de)	2004-03-15	Pharmazeutische präparate zur bekämpfung oder prophylaxe von mikroorganismen infizierten oberflächen
UY26763A1 (es)	2001-08-27	Inmunización del ganado lacteo con proteína gapc quimérica contra infección por estreptococo.
DK1343896T3 (da)	2007-04-10	Lille syreoplöseligt sporeprotein og anvendelser deraf
CY1105343T1 (el)	2010-03-03	Σταφυλοκοκκικη πρωτεϊνη αναστολης του χημειοτακτισμου (chips) και η χρηση αυτης
ATE301194T1 (de)	2005-08-15	Beta-defensine
PT1276495E (pt)	2006-08-31	Utilizacao de tensioactivo pulmonar recombinante para o tratamento precoce de doencas pulmonares agudas
UY26764A1 (es)	2001-09-28	Inmunización del ganado lacteo con proteína gapc contra infección por estreptococo.
NZ504614A (en)	2002-12-20	Echinocandin derivatives and application as anti-fungal agents
BR0309569A (pt)	2005-03-22	Vacinas em combinação que incluem polipeptìdeos imunogênicos de fator camp e gapc
ATE452191T1 (de)	2010-01-15	Gruppe-b streptococcus antigene und entsprechende dna-fragmente