ATE362992T1 - Herstellung von alpha -hydroxy-carboxy säure mit hilfe von einem gekoppelten enzym system - Google Patents

Herstellung von alpha -hydroxy-carboxy säure mit hilfe von einem gekoppelten enzym system

Info

Publication number: ATE362992T1
Authority: AT; Austria
Prior art keywords: alpha; hydroxy; salts; carboxylic acids; production
Prior art date: 2000-10-17

Application number

AT01983974T

Other languages

English (en)

Inventor

Richard Senkpeil

David Pantaleone

Paul Taylor

Original Assignee

Excelsyn Molecular Dev Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-17

Filing date

2001-10-17

Publication date

2007-06-15

2001-10-17 Application filed by Excelsyn Molecular Dev Ltd filed Critical Excelsyn Molecular Dev Ltd

2007-06-15 Application granted granted Critical

2007-06-15 Publication of ATE362992T1 publication Critical patent/ATE362992T1/de

Links

102000004190 Enzymes Human genes 0.000 title abstract 3
108090000790 Enzymes Proteins 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 6
150000004677 hydrates Chemical class 0.000 abstract 3
102000003855 L-lactate dehydrogenase Human genes 0.000 abstract 1
108700023483 L-lactate dehydrogenases Proteins 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000001590 oxidative effect Effects 0.000 abstract 1
238000004064 recycling Methods 0.000 abstract 1
239000000758 substrate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Chemical Kinetics & Catalysis (AREA)
Physics & Mathematics (AREA)
General Chemical & Material Sciences (AREA)
Plant Pathology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Enzymes And Modification Thereof (AREA)
Pyridine Compounds (AREA)
Indole Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

AT01983974T 2000-10-17 2001-10-17 Herstellung von alpha -hydroxy-carboxy säure mit hilfe von einem gekoppelten enzym system ATE362992T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US24117700P	2000-10-17	2000-10-17

Publications (1)

Publication Number	Publication Date
ATE362992T1 true ATE362992T1 (de)	2007-06-15

Family

ID=22909567

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01983974T ATE362992T1 (de)	2000-10-17	2001-10-17	Herstellung von alpha -hydroxy-carboxy säure mit hilfe von einem gekoppelten enzym system

Country Status (8)

Country	Link
US (1)	US20040053382A1 (de)
EP (1)	EP1326993B1 (de)
JP (1)	JP2004511249A (de)
AT (1)	ATE362992T1 (de)
AU (1)	AU2002215360A1 (de)
CA (1)	CA2426594A1 (de)
DE (1)	DE60128581T2 (de)
WO (1)	WO2002033110A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20090029429A1 (en) *	2004-08-13	2009-01-29	Kaneka Corporation	Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative
EP1795602B1 (de) *	2004-09-17	2010-05-19	Sumitomo Chemical Company, Limited	Verfahren zur herstellung sulfurierter hydroxycarbonsäure
AU2005317189A1 (en) *	2004-12-16	2006-06-22	Merck & Co., Inc.	Process for the synthesis of (S)-1-(3,5-bis(trifluoromethyl)-phenyl)ethan-1-ol
WO2006129320A2 (en) *	2005-06-01	2006-12-07	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Biodegradable polymers having a pre-determined chirality
JP4962016B2 (ja) *	2006-09-25	2012-06-27	住友化学株式会社	含硫ヒドロキシカルボン酸の製造法
AU2007293373A1 (en)	2006-09-01	2008-03-13	Merck Sharp & Dohme Corp.	Inhibitors of 5 -lipoxygenase activating protein (FLAP)
CN101517087B (zh) *	2006-09-25	2011-11-23	住友化学株式会社	制备2-羟基-4-(烷硫基或芳硫基)-1-丁酸的方法
US8404465B2 (en)	2009-03-11	2013-03-26	Celexion, Llc	Biological synthesis of 6-aminocaproic acid from carbohydrate feedstocks
CN103041380B (zh) *	2012-12-28	2014-08-06	中国医学科学院输血研究所	人抗凝血酶制剂干热处理过程中的稳定剂
CN103789247B (zh) *	2014-02-14	2015-06-24	江南大学	一种全细胞转化生产α-酮异己酸的方法
CN104830815B (zh) *	2015-06-02	2018-02-23	江南大学	一种采用全细胞转化高效生产α‑苯丙酮酸的方法
CN105603007B (zh) *	2016-02-15	2019-07-23	江南大学	一种微生物转化的方法
CN105603010B (zh) *	2016-02-15	2019-07-23	江南大学	一种微生物转化的方法
CN108624576B (zh) *	2018-04-25	2020-11-03	江南大学	一种l-氨基酸脱氨酶的突变体及其制备方法与应用
CN109136205B (zh) *	2018-08-10	2021-08-27	浙江正硕生物科技有限公司	一种耐热性提高的l-氨基酸脱氨酶突变体及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2930087A1 (de) *	1979-07-25	1981-02-26	Biotechnolog Forschung Gmbh	Verfahren zur kontinuierlichen enzymatischen umwandlung von wasserloeslichen alpha -ketocarbonsaeuren in die entsprechenden alpha -hydroxycarbonsaeuren
ATE98697T1 (de) *	1988-06-06	1994-01-15	Ciba Geigy Ag	Verfahren zur herstellung von hydroxysaeuren.
FI932960A7 (fi) *	1990-12-26	1993-06-24	Monsanto Co	Hedelmien kypsymisen ja kasvien vanhenemisen kontrollointi
US5397700A (en) *	1991-10-31	1995-03-14	University Of Toledo	Method of producing products with a bilayer pellet containing a coimmobilized enzyme system that maintains a ph difference
WO1993013215A1 (en) *	1991-12-23	1993-07-08	Genzyme Limited	Synthesis of homochiral 2-hydroxy acids
CA2121972A1 (en) *	1993-05-06	1994-11-07	Konrad Lerch	Substituted valeric acid
GB9413710D0 (en) *	1994-07-07	1994-08-24	Genzyme Ltd	Chiral synthesis

2001
- 2001-10-17 AT AT01983974T patent/ATE362992T1/de not_active IP Right Cessation
- 2001-10-17 JP JP2002536078A patent/JP2004511249A/ja active Pending
- 2001-10-17 WO PCT/US2001/032243 patent/WO2002033110A2/en not_active Ceased
- 2001-10-17 AU AU2002215360A patent/AU2002215360A1/en not_active Abandoned
- 2001-10-17 DE DE60128581T patent/DE60128581T2/de not_active Expired - Lifetime
- 2001-10-17 EP EP01983974A patent/EP1326993B1/de not_active Expired - Lifetime
- 2001-10-17 US US10/433,835 patent/US20040053382A1/en not_active Abandoned
- 2001-10-17 CA CA002426594A patent/CA2426594A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1326993A2 (de)	2003-07-16
WO2002033110A2 (en)	2002-04-25
DE60128581T2 (de)	2008-02-14
WO2002033110A3 (en)	2003-02-13
AU2002215360A1 (en)	2002-04-29
JP2004511249A (ja)	2004-04-15
US20040053382A1 (en)	2004-03-18
CA2426594A1 (en)	2002-04-25
DE60128581D1 (de)	2007-07-05
EP1326993B1 (de)	2007-05-23

Similar Documents

Publication	Publication Date	Title
ATE362992T1 (de)	2007-06-15	Herstellung von alpha -hydroxy-carboxy säure mit hilfe von einem gekoppelten enzym system
EP1818411A1 (de)	2007-08-15	Verfahren zur Herstellung von optisch aktiven chiralen Aminen
ATE366725T1 (de)	2007-08-15	Verfahren zur herstellung von gereinigten 1,3- substituierten imidazoliumsalzen
JP2010502202A (ja)	2010-01-28	細菌性オメガアミノ基転移酵素を利用したラセミアミン混合物の光学的分解能による光学活性ｎ−保護３−アミノピロリジン又は光学活性ｎ−保護３−アミノピペリジン及び対応するケトンの調製方法
ATE450607T1 (de)	2009-12-15	Rhodococcus-stamm, nitrilase-gen aus rhodococcus, nitrilhydratas-gen und amidase-gen und verfahren zur herstellung carboxylsäuren unter deren verwendung
ATE126829T1 (de)	1995-09-15	Verfahren zur herstellung von salzen des l- ornithins.
CN103966276A (zh)	2014-08-06	酶催化法合成dl-丝氨酸的方法
DK0625571T3 (da)	2000-12-18	Mikroorganismer, deres anvendelse samt fremgangsmåde til fremstilling af L-alfa-aminosyrer
IL161358A0 (en)	2004-09-27	Process for preparing insulin compounds
Soda et al.	2001	One-pot chemo-enzymatic enantiomerization of racemates
BR8601656A (pt)	1986-12-16	Processo para racemizacao de uma amida de n-benzilideno amino-acido opticamente ativa,processos para preparar uma amida dl-amino-acido e processo para preparar um l-amino-acido
BR9707656A (pt)	1999-07-27	Processo para a produção de um produto de condensação
WO2002101003A3 (fr)	2004-02-26	Preparation stereoselective de l-acides amines cycliques
ATE265541T1 (de)	2004-05-15	Verfahren zur fermentativen herstellung von nicht-proteinogenen l-aminosäuren
ATE266635T1 (de)	2004-05-15	Verfahren zur herstellung von zofenopril- calciumsalz
ATE35826T1 (de)	1988-08-15	Verfahren zur herstellung von l-alphaaminos\|uren.
ATE327218T1 (de)	2006-06-15	Verfahren zur herstellung von 1-methyl-3- nitroguanidin
AU2321900A (en)	2000-08-18	Process for the preparation of alpha-aminoketones
PT1066294E (pt)	2003-03-31	Novo processo para a producao fermentativa de cefalosporina
Ohishi et al.	2007	Enantioselective synthesis of D-and L-α-methylcysteine with hydantoinase
WO2002008439A1 (fr)	2002-01-31	Procede d'elaboration d'acides 2-amino
WO2003085091A3 (en)	2004-04-08	Reversible association of nucleic acid with a carboxylated substrate
WO2002095045A3 (fr)	2003-12-24	Procede de preparation d'acides carboxyliques aliphatiques par hydrolyse enzymatique de composes nitriles aliphatiques
IT8050073A1 (it)	1982-05-04	PROCEDIMENTO PER PRODURRE ACIDO D(-)-β-IDROSSI-ISOBUTIRRICO.
WO2004081220A3 (en)	2005-01-27	A process for enzymatically resolving an enantiomeric mixture of alpha-hydroxy acids

Legal Events

Date	Code	Title	Description
2007-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties