ATE364174T1 - Optische detektion in einem mehrkanaligen bioseparationssystem - Google Patents
Optische detektion in einem mehrkanaligen bioseparationssystemInfo
- Publication number
- ATE364174T1 ATE364174T1 AT02707606T AT02707606T ATE364174T1 AT E364174 T1 ATE364174 T1 AT E364174T1 AT 02707606 T AT02707606 T AT 02707606T AT 02707606 T AT02707606 T AT 02707606T AT E364174 T1 ATE364174 T1 AT E364174T1
- Authority
- AT
- Austria
- Prior art keywords
- detection
- radiation
- channel
- separation
- light sources
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title abstract 7
- 230000003287 optical effect Effects 0.000 title 1
- 230000005855 radiation Effects 0.000 abstract 6
- 238000000926 separation method Methods 0.000 abstract 4
- 238000005251 capillar electrophoresis Methods 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 238000001917 fluorescence detection Methods 0.000 abstract 1
- 230000001360 synchronised effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44782—Apparatus specially adapted therefor of a plurality of samples
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26455301P | 2001-01-26 | 2001-01-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE364174T1 true ATE364174T1 (de) | 2007-06-15 |
Family
ID=23006573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02707606T ATE364174T1 (de) | 2001-01-26 | 2002-01-28 | Optische detektion in einem mehrkanaligen bioseparationssystem |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6828567B2 (de) |
| EP (1) | EP1354193B1 (de) |
| JP (1) | JP4202759B2 (de) |
| CN (1) | CN1257405C (de) |
| AT (1) | ATE364174T1 (de) |
| AU (1) | AU2002242004A1 (de) |
| CA (1) | CA2436098C (de) |
| DE (1) | DE60220497T2 (de) |
| TW (1) | TWI243242B (de) |
| WO (1) | WO2002059592A2 (de) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6406604B1 (en) | 1999-11-08 | 2002-06-18 | Norberto A. Guzman | Multi-dimensional electrophoresis apparatus |
| US7329388B2 (en) | 1999-11-08 | 2008-02-12 | Princeton Biochemicals, Inc. | Electrophoresis apparatus having staggered passage configuration |
| ATE522802T1 (de) * | 2001-01-26 | 2011-09-15 | Qiagen Sciences Llc | Mehrkanalkassette für biotrennung |
| US6995841B2 (en) * | 2001-08-28 | 2006-02-07 | Rice University | Pulsed-multiline excitation for color-blind fluorescence detection |
| US7208072B2 (en) * | 2002-01-18 | 2007-04-24 | Biocal Technology, Inc. | Multi-segment cartridge for bio-separation with multiplexed fluorescence detection |
| CN101348763B (zh) * | 2002-06-20 | 2012-07-18 | 普里梅拉蒂斯有限公司 | 用于多聚核苷酸检测和定量的设备 |
| JP2006515672A (ja) * | 2002-12-20 | 2006-06-01 | ノースイースタン・ユニバーシティ | 精密制御型サーモスタット |
| BRPI0416120A (pt) * | 2003-11-05 | 2007-01-02 | Max Planck Gesellschaft | dispositivo e método de medição da fluorescência de pelo menos uma amostra em pelo menos uma cámara de amostras e dispositivo de separação |
| US8007725B2 (en) | 2003-11-07 | 2011-08-30 | Princeton Biochemicals, Inc. | Electrophoresis apparatus having valve system |
| CA2563310A1 (en) | 2003-11-07 | 2005-05-26 | Princeton Biochemicals, Inc. | Multi-dimensional electrophoresis apparatus |
| US20050257885A1 (en) * | 2004-05-24 | 2005-11-24 | Nanostream, Inc. | Capillary multi-channel optical flow cell |
| US20060082768A1 (en) * | 2004-08-31 | 2006-04-20 | Wilson Denise M | Miniaturized fluorescence analysis system |
| US7391512B2 (en) * | 2004-12-22 | 2008-06-24 | Avago Technologies General Ip Pte. Ltd. | Integrated optoelectronic system for measuring fluorescence or luminescence emission decay |
| KR100647317B1 (ko) * | 2005-02-03 | 2006-11-23 | 삼성전자주식회사 | 다채널 형광 측정용 광학계 및 이를 채용한 다채널 형광시료 분석 장치 |
| CN101175560B (zh) * | 2005-05-11 | 2012-12-26 | 亚申科技研发中心(上海)有限公司 | 高通量物质处理系统 |
| JP4756948B2 (ja) * | 2005-08-08 | 2011-08-24 | ベイバイオサイエンス株式会社 | フローサイトメータおよびフローサイトメトリ方法 |
| US20070131870A1 (en) * | 2005-12-12 | 2007-06-14 | Combisep | Multiplexed CE fluorescence system |
| US8496879B2 (en) | 2006-02-08 | 2013-07-30 | Molecular Devices, Llc | Optical detection utilizing cartridge with tunable filter assembly |
| US8119066B2 (en) * | 2006-02-08 | 2012-02-21 | Molecular Devices, Llc | Multimode reader |
| US8968658B2 (en) | 2006-02-08 | 2015-03-03 | Molecular Devices, Llc | Luminescence measurement utilizing cartridge with integrated detector |
| CN101405591A (zh) | 2006-03-23 | 2009-04-08 | 纳诺多普科技有限责任公司 | 对于由表面张力保持的多个样本进行光学测量的仪器 |
| AU2007289057C1 (en) * | 2006-09-01 | 2014-01-16 | Pacific Biosciences Of California, Inc. | Substrates, systems and methods for analyzing materials |
| US8207509B2 (en) | 2006-09-01 | 2012-06-26 | Pacific Biosciences Of California, Inc. | Substrates, systems and methods for analyzing materials |
| DE102006048346A1 (de) * | 2006-10-12 | 2008-04-17 | Eppendorf Ag | Verfahren zur Vorrichtung zur quantitativen Echtzeitanalyse von fluoreszierenden Proben |
| US8500980B1 (en) * | 2006-10-24 | 2013-08-06 | Qiagen Sciences, Llc | Method and apparatus for high speed genotyping |
| US8163152B1 (en) * | 2006-11-09 | 2012-04-24 | Qiagen Sciences, Llc | Method and apparatus for high speed carbohydrate analysis |
| DE102006056596A1 (de) * | 2006-11-30 | 2008-06-05 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Vorrichtung zum ortstaufgelösten Detektieren von Fluoreszenzsignalen |
| US7738094B2 (en) * | 2007-01-26 | 2010-06-15 | Becton, Dickinson And Company | Method, system, and compositions for cell counting and analysis |
| JP5297447B2 (ja) | 2007-03-26 | 2013-09-25 | イージーン インコーポレイテッド | 毛管、生体分析用のカートリッジ、生体分析システム、および生体分析のための方法 |
| JP2009002694A (ja) * | 2007-06-19 | 2009-01-08 | Nippon Sheet Glass Co Ltd | 蛍光測定用プローブ |
| US20090004056A1 (en) * | 2007-06-26 | 2009-01-01 | Dade Behring Inc. | Clinical Sample Analysis System Having An Analyzer Positioning Mechanism |
| DE102008001322A1 (de) * | 2008-04-22 | 2009-10-29 | Linos Photonics Gmbh & Co. Kg | System zur optischen Analyse von Probenarrays |
| JP2011527439A (ja) * | 2008-07-07 | 2011-10-27 | グラクソスミスクライン エルエルシー | 組成物を分析するための複数のエネルギー源を用いる方法、装置およびシステム |
| DE102008050109B4 (de) * | 2008-07-21 | 2010-06-17 | Ancosys Gmbh | Optischer Sensor |
| WO2010033193A2 (en) | 2008-09-16 | 2010-03-25 | Pacific Biosciences Of California, Inc. | Substrates and optical systems and methods of use thereof |
| WO2010068670A1 (en) * | 2008-12-09 | 2010-06-17 | Advanced Analytical Technologies, Inc. | Capillary electrophoresis fluorescent detection system |
| US8784626B2 (en) | 2010-01-28 | 2014-07-22 | Bioptic, Inc. | Bio-analysis using ball-ended incident and output optical fibers |
| US9410891B2 (en) | 2010-02-19 | 2016-08-09 | Pacific Biosciences Of California, Inc. | Optics collection and detection system and method |
| US8994946B2 (en) | 2010-02-19 | 2015-03-31 | Pacific Biosciences Of California, Inc. | Integrated analytical system and method |
| EP2569614A4 (de) * | 2010-05-12 | 2018-01-17 | Li-Cor, Inc. | Abtastung mit hohem dynamikbereich und eingeschränktem kanalübersprechen |
| JP5930482B2 (ja) * | 2010-08-24 | 2016-06-08 | バイオプティック インコーポレイテッドBioptic, Inc. | 使い捨て生体分析カートリッジ、及び生体分析を、同カートリッジを用いて行なう装置 |
| CN101980007A (zh) * | 2010-10-11 | 2011-02-23 | 广东达元食品药品安全技术有限公司 | 一种基于led灯多光路切换的比色系统 |
| US9140666B2 (en) | 2012-03-15 | 2015-09-22 | Advanced Analytical Technologies, Inc. | Capillary electrophoresis system |
| WO2013033080A1 (en) * | 2011-08-29 | 2013-03-07 | Wayne State University | Device and method for optimizing photobiological processes |
| JP5817369B2 (ja) * | 2011-09-13 | 2015-11-18 | ソニー株式会社 | スペクトル解析装置及び微小粒子測定装置、並びにスペクトル解析あるいはスペクトルチャート表示のための方法及びプログラム |
| EP2780705B1 (de) | 2011-11-16 | 2018-09-19 | Becton, Dickinson and Company | Verfahren und systeme zum nachweis eines analyts in einer probe |
| EP2795271B1 (de) | 2011-12-22 | 2021-07-28 | F. Hoffmann-La Roche AG | Verlängerung der lebensdauer einer lichtquelle in einem optischen system |
| CN102539512B (zh) * | 2012-02-10 | 2014-02-26 | 上海康盈生物科技有限公司 | 一种用于同时检测多个样品中糖化血红蛋白HbAlc的多通道毛细管电泳检测方法 |
| US9182336B2 (en) * | 2012-03-02 | 2015-11-10 | Laxco, Inc. | Multichannel analytical instruments for use with specimen holders |
| US11016057B2 (en) | 2012-03-15 | 2021-05-25 | Agilent Technologies, Inc. | Pulse-field multiplex capillary electrophoresis system |
| US11340191B2 (en) | 2012-03-15 | 2022-05-24 | Agilent Technologies, Inc. | UV-absorbance multichannel capillary electrophoresis system |
| CN102661984B (zh) * | 2012-04-25 | 2014-01-15 | 北方工业大学 | 一种基于多路电化学传感器寿命延长的控制电路 |
| US9372308B1 (en) | 2012-06-17 | 2016-06-21 | Pacific Biosciences Of California, Inc. | Arrays of integrated analytical devices and methods for production |
| CN103513328A (zh) * | 2012-06-28 | 2014-01-15 | 耿征 | 结构光发生装置、结构光发生方法及微型三维成像装置 |
| US20140034829A1 (en) * | 2012-08-06 | 2014-02-06 | Peter Crozier | System and method for irradiating an etem-sample with light |
| EP2929308A4 (de) | 2012-12-05 | 2015-12-16 | Genepoc Inc | Optische abfragevorrichtung |
| WO2014099776A1 (en) | 2012-12-18 | 2014-06-26 | Pacific Biosciences Of California, Inc. | Illumination of optical analytical devices |
| ES2692407T3 (es) | 2013-01-11 | 2018-12-03 | Becton, Dickinson And Company | Dispositivo de ensayo de punto de cuidado de bajo coste |
| US9624540B2 (en) | 2013-02-22 | 2017-04-18 | Pacific Biosciences Of California, Inc. | Integrated illumination of optical analytical devices |
| AU2014332126B2 (en) | 2013-10-07 | 2019-10-31 | Agdia Inc. | Portable testing device for analyzing biological samples |
| JP6632525B2 (ja) | 2013-11-06 | 2020-01-22 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | マイクロ流体デバイスならびにその製造方法および使用方法 |
| BR112016010721B1 (pt) | 2013-11-13 | 2021-06-01 | Becton, Dickinson And Company | Método e sistema de análise de uma amostra para um analito |
| WO2015179098A1 (en) | 2014-05-21 | 2015-11-26 | Integenx Inc. | Fluidic cartridge with valve mechanism |
| EP3092474B1 (de) | 2014-06-12 | 2020-04-22 | Axion Biosystems, Inc. | Multiwell-mikroelektrodenanordnung mit optischer stimulation |
| TWI692633B (zh) | 2014-08-27 | 2020-05-01 | 美商加州太平洋生物科學公司 | 整合式分析裝置之陣列 |
| US11298061B2 (en) | 2014-10-14 | 2022-04-12 | Becton, Dickinson And Company | Blood sample management using open cell foam |
| EP3206581B1 (de) | 2014-10-14 | 2018-09-19 | Becton, Dickinson and Company | Blutprobenverwaltung mittels offenzelligem schaumstoff |
| CN113092563B (zh) | 2014-10-22 | 2024-06-07 | 尹特根埃克斯有限公司 | 用于样品制备、处理和分析的系统和方法 |
| EP4350351A3 (de) | 2015-03-10 | 2024-06-26 | Becton, Dickinson and Company | Mikroprobenverwaltungsvorrichtung für biologische flüssigkeiten |
| EP3271762B1 (de) | 2015-03-16 | 2023-01-04 | Pacific Biosciences of California, Inc. | Analysesystem umfassend integrierte vorrichtungen und systeme zur optischen freiraumkopplung |
| CA2983882C (en) | 2015-05-07 | 2023-10-03 | Scott E. Helgesen | Multiprocessor pipeline architecture |
| US10365434B2 (en) | 2015-06-12 | 2019-07-30 | Pacific Biosciences Of California, Inc. | Integrated target waveguide devices and systems for optical coupling |
| DE102015111282A1 (de) * | 2015-07-13 | 2017-01-19 | Stiftung Caesar Center Of Advanced European Studies And Research | Verfahren zum Beobachten eines chemischen und/oder biologischen Vorgangs |
| US20170038299A1 (en) * | 2015-08-07 | 2017-02-09 | Sentinel Monitoring Systems, Inc. | Online process monitoring |
| CA2996863C (en) | 2015-09-01 | 2021-04-13 | Becton, Dickinson And Company | Depth filtration device for separating specimen phases |
| JP6646204B2 (ja) * | 2015-09-03 | 2020-02-14 | 東亜ディーケーケー株式会社 | 紫外線光源を用いる測定装置 |
| DE102016200271A1 (de) | 2016-01-13 | 2017-07-13 | Institut Dr. Foerster Gmbh & Co. Kg | Vorrichtung zur Erzeugung und Messung einer Emission |
| TWI586957B (zh) * | 2016-06-24 | 2017-06-11 | 諾貝爾生物有限公司 | 多通道螢光檢測系統及其方法 |
| CN105973860B (zh) * | 2016-06-29 | 2019-07-30 | 山东科立森生物股份有限公司 | 一种毛细管电泳检测系统及检测方法 |
| CN105973859B (zh) * | 2016-06-29 | 2019-01-29 | 山东科立森生物股份有限公司 | 一种毛细管电泳检测系统及检测方法 |
| JP2020509391A (ja) | 2017-01-10 | 2020-03-26 | フォトスイッチ・バイオサイエンシズ・インコーポレイテッド | 検出のためのシステムおよび方法 |
| US11604162B2 (en) | 2017-02-24 | 2023-03-14 | Life Technologies Corporation | Optical systems and methods for sample separation |
| CN110785658B (zh) * | 2017-06-27 | 2022-12-06 | 安捷伦科技有限公司 | 脉冲场多重毛细管电泳系统 |
| EP3444603B1 (de) | 2017-08-15 | 2024-08-07 | Agilent Technologies, Inc. | Verbessertes uv-absorptions-mehrkanal-kapillarenelektrophoresesystem |
| GB2619179B (en) * | 2019-05-22 | 2024-03-27 | Hitachi High Tech Corp | Analysis device and analysis method |
| CN114729915A (zh) * | 2019-11-14 | 2022-07-08 | Dh科技发展私人贸易有限公司 | 用于毛细管电泳的双模式扫描光学系统 |
| US12535420B2 (en) | 2020-02-18 | 2026-01-27 | Pacific Biosciences Of California, Inc. | Highly multiplexed nucleic acid sequencing systems |
| WO2021210144A1 (ja) * | 2020-04-16 | 2021-10-21 | 株式会社日立ハイテク | 電気泳動システム |
| JP2024516290A (ja) | 2021-05-04 | 2024-04-12 | パシフィック・バイオサイエンシズ・オブ・カリフォルニア・インク. | 縮小されたスケールの単位セルを伴う統合された分析デバイスのアレイ |
| JP2024533669A (ja) * | 2021-09-24 | 2024-09-12 | コーニンクレッカ フィリップス エヌ ヴェ | 呼吸ガス感知 |
| CN115747035B (zh) * | 2023-01-05 | 2023-05-09 | 苏州和迈精密仪器有限公司 | 一种基于离散三维荧光技术的连续扫描监测分析系统 |
| CN120283162A (zh) * | 2023-03-24 | 2025-07-08 | 株式会社日立高新技术 | 毛细管电泳装置 |
| CN116625246A (zh) * | 2023-05-04 | 2023-08-22 | 中国工程物理研究院激光聚变研究中心 | 一种新型多模式轴向色差共焦传感器 |
| CN118150541B (zh) * | 2024-04-24 | 2024-08-02 | 北京林业大学 | 一种多通道荧光检测装置 |
Family Cites Families (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3675210A (en) * | 1966-05-16 | 1972-07-04 | Digital Data Systems | Method and apparatus for the transmission of acquired data in the form of magnitude representing signals and signals representing changes of scale of magnitude |
| US4100416A (en) | 1977-03-02 | 1978-07-11 | Block Engineering, Inc. | Serum fluorescence suppression |
| JPS55156840A (en) * | 1979-05-25 | 1980-12-06 | Olympus Optical Co Ltd | Specimen detector |
| US4300834A (en) | 1980-05-22 | 1981-11-17 | Baird Corporation | Inductively coupled plasma atomic fluorescence spectrometer |
| US4675300A (en) | 1985-09-18 | 1987-06-23 | The Board Of Trustees Of The Leland Stanford Junior University | Laser-excitation fluorescence detection electrokinetic separation |
| DE68927019T2 (de) | 1988-04-29 | 1997-01-23 | Beckman Instruments Inc | Kassette mit einem kapillaren Detektor für Elektroforese |
| US6001230A (en) | 1988-04-29 | 1999-12-14 | Beckman Coulter, Inc. | Automated capillary electrophoresis apparatus |
| US5062942A (en) | 1989-04-12 | 1991-11-05 | Hitachi, Ltd. | Fluorescence detection type electrophoresis apparatus |
| US5043585A (en) | 1990-01-03 | 1991-08-27 | Degussa Aktiengesellschaft | Method and apparatus for measurement of the fluorescence relaxation period of a fluorescent substance |
| US5066382A (en) | 1990-01-25 | 1991-11-19 | Spectra-Physics, Inc. | Thermal control for capillary electrophoresis apparatus |
| US5529679A (en) | 1992-02-28 | 1996-06-25 | Hitachi, Ltd. | DNA detector and DNA detection method |
| JP2785530B2 (ja) | 1991-09-13 | 1998-08-13 | 株式会社日立製作所 | 電気泳動装置 |
| US5413686A (en) | 1992-07-17 | 1995-05-09 | Beckman Instruments, Inc. | Multi-channel automated capillary electrophoresis analyzer |
| US5736410A (en) | 1992-09-14 | 1998-04-07 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
| US5324401A (en) | 1993-02-05 | 1994-06-28 | Iowa State University Research Foundation, Inc. | Multiplexed fluorescence detector system for capillary electrophoresis |
| FR2701318B1 (fr) | 1993-02-09 | 1995-03-17 | Inst Francais Du Petrole | Dispositif perfectionné et méthode pour mesurer optiquement des caractéristiques d'une substance. |
| US5338427A (en) | 1993-02-26 | 1994-08-16 | Biometric Imaging Inc. | Single use separation cartridge for a capillary electrophoresis instrument |
| US5416879A (en) | 1993-03-29 | 1995-05-16 | World Precision Instruments, Inc. | Apparatus and method for measuring light absorption in small aqueous fluid samples |
| US5439578A (en) | 1993-06-03 | 1995-08-08 | The Governors Of The University Of Alberta | Multiple capillary biochemical analyzer |
| IL107508A (en) | 1993-11-05 | 1996-12-05 | Orbotech Ltd | Method and apparatus for recording on optically-sensitive media |
| US5539201A (en) | 1994-03-14 | 1996-07-23 | Pro-Optical Technologies, Inc. | Multiple channel driver for fiber optic coupled sensors and switches |
| JP3434914B2 (ja) | 1994-11-11 | 2003-08-11 | 株式会社日立製作所 | 電気泳動装置用試料保持装置、電気泳動装置及び電気泳動装置への試料注入方法 |
| US5543018A (en) | 1995-02-13 | 1996-08-06 | Visible Genetics Inc. | Method and apparatus for automated electrophoresis using light polarization detector |
| US5560811A (en) | 1995-03-21 | 1996-10-01 | Seurat Analytical Systems Incorporated | Capillary electrophoresis apparatus and method |
| US5582702A (en) | 1995-04-26 | 1996-12-10 | Ethrog Biotechnology Ltd. | Apparatus and method for electrophoresis |
| US5675155A (en) | 1995-04-26 | 1997-10-07 | Beckman Instruments, Inc. | Multicapillary fluorescent detection system |
| US5582705A (en) | 1995-05-19 | 1996-12-10 | Iowa State University Research Foundation, Inc. | Multiplexed capillary electrophoresis system |
| US5784157A (en) | 1995-11-21 | 1998-07-21 | The Research Foundation Of State University Of New York | Method and apparatus for identifying fluorophores |
| US5650846A (en) | 1995-11-21 | 1997-07-22 | Hewlett-Packard Company | Microcolumnar analytical system with optical fiber sensor |
| AT403745B (de) | 1996-02-29 | 1998-05-25 | Avl Verbrennungskraft Messtech | Messanordnung mit einem für anregungs- und messstrahlung transparentem trägerelement |
| US5846727A (en) | 1996-06-06 | 1998-12-08 | Board Of Supervisors Of Louisiana State University And Agricultural & Mechanical College | Microsystem for rapid DNA sequencing |
| US5763277A (en) | 1996-06-10 | 1998-06-09 | Transgenomic Incorporated | Fiber optic axial view fluorescence detector and method of use |
| US6361672B1 (en) * | 1996-06-10 | 2002-03-26 | Transgenomic, Inc. | Multiple laser diode electromagnetic radiation source in multiple electrophoresis channel systems |
| JP3400650B2 (ja) | 1996-06-28 | 2003-04-28 | 株式会社日立製作所 | 電気泳動分離検出方法及び装置 |
| US5800784A (en) | 1996-07-09 | 1998-09-01 | Horn; Marcus J. | Chemical sample treatment system and cassette, and methods for effecting multistep treatment process |
| US6074827A (en) | 1996-07-30 | 2000-06-13 | Aclara Biosciences, Inc. | Microfluidic method for nucleic acid purification and processing |
| WO1998010122A1 (en) * | 1996-09-03 | 1998-03-12 | Northeastern University | Microfabricated hybrid capillary array and multichannel detection assembly |
| US6063251A (en) | 1997-05-30 | 2000-05-16 | Spectrumedix Corporation | Electrically insulated capillary arrays for electrophoretic applications |
| US5885430A (en) | 1996-10-04 | 1999-03-23 | Spectrumedix Corporation | Capillary tube holder for an electrophoretic apparatus |
| US5790727A (en) | 1997-02-05 | 1998-08-04 | Brookhaven Science Associates Llc | Laser illumination of multiple capillaries that form a waveguide |
| JPH10239278A (ja) | 1997-02-24 | 1998-09-11 | Hitachi Ltd | 電気泳動装置 |
| US6445448B1 (en) | 1997-03-12 | 2002-09-03 | Corning Applied Technologies, Corp. | System and method for molecular sample measurement |
| US6084667A (en) * | 1997-03-12 | 2000-07-04 | Nz Applied Technologies | System and method for molecular sample measurement |
| CA2284870C (en) | 1997-03-17 | 2003-11-25 | Tsi Incorporated | System for detecting fluorescing components in aerosols |
| US6027627A (en) | 1997-06-30 | 2000-02-22 | Spectrumedix Corporation | Automated parallel capillary electrophoretic system |
| US6597450B1 (en) * | 1997-09-15 | 2003-07-22 | Becton, Dickinson And Company | Automated Optical Reader for Nucleic Acid Assays |
| US6043880A (en) | 1997-09-15 | 2000-03-28 | Becton Dickinson And Company | Automated optical reader for nucleic acid assays |
| US6054032A (en) | 1998-01-27 | 2000-04-25 | 3M Innovative Properties Company | Capillary electrophoresis array |
| US6326213B1 (en) | 1998-02-09 | 2001-12-04 | The Boards Of Govenors For Higher Education, State Of Rhode Island And Providence Plantations | Acoustic standing-wave enhancement of a fiber-optic Salmonella biosensor |
| US6103083A (en) | 1998-02-20 | 2000-08-15 | Tetragen | Capillary electrophoresis apparatus and method |
| US6369893B1 (en) | 1998-05-19 | 2002-04-09 | Cepheid | Multi-channel optical detection system |
| US6759662B1 (en) * | 1998-07-28 | 2004-07-06 | Ce Resources Pte. Ltd. | Optical detection system |
| US6104485A (en) | 1998-10-07 | 2000-08-15 | World Precision Instruments, Inc. | Method and apparatus for optical measurement of very small fluid samples |
| US6184990B1 (en) | 1999-12-22 | 2001-02-06 | Beckman Coulter, Inc. | Miniature multiple wavelength excitation and emission optical system and method for laser-induced fluorescence detectors in capillary electrophoresis |
-
2002
- 2002-01-28 AT AT02707606T patent/ATE364174T1/de not_active IP Right Cessation
- 2002-01-28 WO PCT/US2002/002514 patent/WO2002059592A2/en not_active Ceased
- 2002-01-28 TW TW091101407A patent/TWI243242B/zh not_active IP Right Cessation
- 2002-01-28 JP JP2002559658A patent/JP4202759B2/ja not_active Expired - Lifetime
- 2002-01-28 CN CN02805754.6A patent/CN1257405C/zh not_active Expired - Lifetime
- 2002-01-28 US US10/060,052 patent/US6828567B2/en not_active Expired - Lifetime
- 2002-01-28 EP EP02707606A patent/EP1354193B1/de not_active Expired - Lifetime
- 2002-01-28 DE DE60220497T patent/DE60220497T2/de not_active Expired - Lifetime
- 2002-01-28 CA CA2436098A patent/CA2436098C/en not_active Expired - Lifetime
- 2002-01-28 AU AU2002242004A patent/AU2002242004A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002242004A1 (en) | 2002-08-06 |
| EP1354193B1 (de) | 2007-06-06 |
| CA2436098A1 (en) | 2002-08-01 |
| JP4202759B2 (ja) | 2008-12-24 |
| CN1494655A (zh) | 2004-05-05 |
| CA2436098C (en) | 2014-04-01 |
| US20020113213A1 (en) | 2002-08-22 |
| WO2002059592A3 (en) | 2002-12-19 |
| US6828567B2 (en) | 2004-12-07 |
| WO2002059592A2 (en) | 2002-08-01 |
| TWI243242B (en) | 2005-11-11 |
| DE60220497T2 (de) | 2008-01-31 |
| DE60220497D1 (de) | 2007-07-19 |
| CN1257405C (zh) | 2006-05-24 |
| EP1354193A2 (de) | 2003-10-22 |
| JP2004521334A (ja) | 2004-07-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60220497D1 (de) | Optische detektion in einem mehrkanaligen bioseparationssystem | |
| MX2019008347A (es) | Secuenciamiento de canal bioptico, de una sola fuente de luz. | |
| DE3885104D1 (de) | Mehrkanal-vorrichtung zur analysierung von molekulargasen unter verwendung der laser-erregten raman-lichtstreuung. | |
| DK1484601T3 (da) | Optisk indretning til et assay-aflæsningsapparat | |
| ATE127457T1 (de) | Verfahren zur herstellung polysubstituierten piperazinone. | |
| DE602006015043D1 (de) | Multiplex-fluoreszenzdetektionsvorrichtung mit entfernbaren optischen modulen | |
| ATE537438T1 (de) | Vorrichtung und verfahren zur unterscheidung mehrerer fluoreszenzsignale anhand ihrer anregungswellenlänge | |
| DE59109157D1 (de) | Vorrichtung und Verfahren zur Prüfung von Dokumenten | |
| DE60309476D1 (de) | Optische vorrichtung und verfahren zur messung von lichttransmission | |
| EP1059530A3 (de) | Mehrkanaliger Photoionisationsdetektor zur gleichzeitigen und selektiven Messung von flüchtigen organischen Verbindungen | |
| ATE512350T1 (de) | Scannersystem und verfahren zur erfassung von oberflächen | |
| DK1354192T3 (da) | Flerkanalkasette til bioseparation | |
| ATE154699T1 (de) | Vorrichtung zur trennung von medien in deren bestandteile | |
| GB2377272A (en) | Method and apparatus for DNA sequencing | |
| CY1112888T1 (el) | Μεθοδος παρασκευης της (s)-παντοπραζολης | |
| WO2003034044A3 (en) | Multi-color multiplexed analysis in a bio-separation system | |
| WO2006086659A3 (en) | Column-end fluorescence detection for capillary array electrophoresis | |
| EP3824695A4 (de) | Led-beleuchtungssystem, vorrichtung und dimmverfahren | |
| GB2517865A (en) | Real time optical detection of bacteria | |
| WO2020109399A3 (de) | Vorrichtung und verfahren zur vermessung von halbleiterbasierten lichtquellen | |
| SE9401251D0 (sv) | Sätt och anordning för elektroforetisk analys | |
| US20160018333A1 (en) | Method of calibrating and correcting color-bleed factors for color separation in dna analysis | |
| US6468409B1 (en) | Method and apparatus for detecting substances | |
| CY1110782T1 (el) | Αλατα προσθηκης αναστολεων του ενζυμου μετατροπης της αγγειοτασινης με οξεα δοτες no, η μεθοδος παρασκευης τους και οι φαρμακευτικες συνθεσεις που τα περιεχουν | |
| WO2003001200A3 (en) | Optical detection in bio-separation device having axial radiation input and output and widened detection zone |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |