ATE365219T1 - Glykolisierung des säugetiertyps in pflanzen - Google Patents

Glykolisierung des säugetiertyps in pflanzen

Info

Publication number
ATE365219T1
ATE365219T1 AT00980083T AT00980083T ATE365219T1 AT E365219 T1 ATE365219 T1 AT E365219T1 AT 00980083 T AT00980083 T AT 00980083T AT 00980083 T AT00980083 T AT 00980083T AT E365219 T1 ATE365219 T1 AT E365219T1
Authority
AT
Austria
Prior art keywords
plants
glycolization
mammal
type
normally
Prior art date
Application number
AT00980083T
Other languages
English (en)
Inventor
Hendrikus Bakker
Hendrik Bosch
Original Assignee
Plant Res Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plant Res Int Bv filed Critical Plant Res Int Bv
Application granted granted Critical
Publication of ATE365219T1 publication Critical patent/ATE365219T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT00980083T 1999-10-26 2000-10-26 Glykolisierung des säugetiertyps in pflanzen ATE365219T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99203524 1999-10-26
EP99203523 1999-10-26

Publications (1)

Publication Number Publication Date
ATE365219T1 true ATE365219T1 (de) 2007-07-15

Family

ID=26153384

Family Applications (2)

Application Number Title Priority Date Filing Date
AT00980083T ATE365219T1 (de) 1999-10-26 2000-10-26 Glykolisierung des säugetiertyps in pflanzen
AT06077065T ATE478150T1 (de) 1999-10-26 2000-10-26 Säugetierartige glykosylierung in pflanzen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT06077065T ATE478150T1 (de) 1999-10-26 2000-10-26 Säugetierartige glykosylierung in pflanzen

Country Status (16)

Country Link
US (3) US7781647B2 (de)
EP (3) EP2251426A1 (de)
JP (1) JP4890712B2 (de)
AT (2) ATE365219T1 (de)
AU (1) AU1738401A (de)
BR (1) BRPI0015031B1 (de)
CA (2) CA2389217C (de)
DE (2) DE60044858D1 (de)
DK (2) DK1228231T3 (de)
ES (1) ES2288882T3 (de)
IL (6) IL149271A0 (de)
MX (1) MXPA02004142A (de)
NZ (1) NZ518532A (de)
PT (2) PT1772518E (de)
TR (1) TR200201121T2 (de)
WO (1) WO2001031045A1 (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1137789E (pt) 1998-12-09 2010-10-21 Phyton Holdings Llc Um método para produzir glicoproteínas possuindo glicosilação de tipo humano
CA2388432A1 (en) * 1999-10-21 2001-04-26 Monsanto Company Post-translational modification of recombinant proteins produced in plants
ATE365219T1 (de) 1999-10-26 2007-07-15 Plant Res Int Bv Glykolisierung des säugetiertyps in pflanzen
JP5623683B2 (ja) * 2000-03-22 2014-11-12 フィトン ホールディングス，リミティド ライアビリティ カンパニー 動物型糖鎖付加機能をもつ植物細胞
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
US7632983B2 (en) 2000-07-31 2009-12-15 Biolex Therapeutics, Inc. Expression of monoclonal antibodies in duckweed
US8022270B2 (en) 2000-07-31 2011-09-20 Biolex Therapeutics, Inc. Expression of biologically active polypeptides in duckweed
CN100385006C (zh) 2001-01-19 2008-04-30 陶氏化学公司 利用植物细胞分泌性生产具有人型糖链的糖蛋白的方法
CN1541059A (zh) * 2001-03-06 2004-10-27 �Ϻ���ͨ��ѧ 具有动物型糖链加成功能的植物细胞
GB2377446B (en) * 2001-07-13 2005-06-29 Lars Erik Berglund Expression of cobalamin binding proteins in transgenic plants
CA2478294C (en) * 2002-03-19 2013-09-03 Plant Research International B.V. Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta (1,4)-n-acetylglucosaminyltransferase iii) expression in plants
AU2008202355B2 (en) * 2002-03-19 2011-04-07 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
AU2013205262B2 (en) * 2002-03-19 2016-02-25 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
CA2923247A1 (en) 2002-03-19 2003-09-25 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
AR042145A1 (es) * 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
KR101498588B1 (ko) * 2003-01-22 2015-03-05 로슈 글리카트 아게 융합 구성체와 Ｆｃ 수용체 결합 친화도 및 이펙터 기능이 증가된 항체를 생성하기 위한 이의 용도
EP1536229A1 (de) * 2003-11-26 2005-06-01 Plant Research International B.V. Verfahren zur Identifizierung eines biomolekularen Profils
JP2007535317A (ja) * 2004-04-15 2007-12-06 グライコフィ， インコーポレイテッド 下等真核生物におけるガラクトシル化された糖タンパク質の産生
ATE547526T1 (de) * 2004-05-31 2012-03-15 Kitasato Inst Formerly Known As School Juridical Person Kitasato Gakuen Orale anti-leucocytozoonosis-impfstoffe basierend auf transgenen pflanzen
WO2006004675A2 (en) * 2004-06-25 2006-01-12 Altor Bioscience Corporation Production of tissue factor in plants
JP2006288210A (ja) 2005-04-05 2006-10-26 National Institute Of Advanced Industrial & Technology 糖転移酵素遺伝子の導入による生体内糖鎖伸長の技術
ES2348857T3 (es) 2005-07-12 2010-12-03 Greenovation Biotech Gmbh Mejoras en o relacionadas con la produccion de proteinas.
MX2008009220A (es) 2006-01-17 2008-10-10 Biolex Therapeutics Inc Composiciones y metodos para la humanizacion y optimizacion de n-glicanos en plantas.
WO2007090290A1 (en) * 2006-02-09 2007-08-16 Medicago Inc. Synthesis of sialic acid in plants
EP1878747A1 (de) * 2006-07-11 2008-01-16 greenovation Biotech GmbH Glyco-hergestellte Antikörper
KR101426667B1 (ko) * 2007-04-17 2014-08-06 스티칭 디엔스트 랜드보위쿤디그 온데조에크 비-포유동물 글리코실트랜스퍼라제의 발현에 의한 식물에서의 포유동물형 글리코실화
AU2013203379B2 (en) * 2007-04-17 2016-01-21 Stichting Dienst Landbouwkundig Onderzoek Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
WO2008141806A1 (en) * 2007-05-21 2008-11-27 Bayer Bioscience N.V. Methods and means for producing glycoproteins with altered glycosylation pattern in higher plants
PL2155880T3 (pl) * 2007-06-15 2017-06-30 Medicago Inc. Modyfikacja wytwarzania glikoproteiny w roślinach
DK2318530T3 (en) 2008-07-18 2016-10-03 Medicago Inc Ny epitope to immunization against influenza
US8809009B2 (en) 2009-01-02 2014-08-19 Biomarin Pharmaceutical Inc. Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker
US8232073B2 (en) 2009-01-02 2012-07-31 Zacharon Pharmaceuticals, Inc. Quantification of non-reducing end glycan residual compounds
US9029530B2 (en) 2009-01-02 2015-05-12 Biomarin Pharmaceutical Inc. Detection of oligosaccharides
US20120100609A1 (en) * 2009-03-27 2012-04-26 Crawford Brett E N-linked glycan biosynthesis modulators
WO2013019625A2 (en) 2011-07-29 2013-02-07 The University Of Wyoming Methods of using a bacterial glcnac-6-p 2'-epimerase to promote sialylation of glycoconjugates
US9816107B2 (en) 2011-07-29 2017-11-14 The University Of Wyoming Transgenic insect cells comprising a bacterial GlcNAc-6-P 2′-epimerase
WO2013119419A1 (en) 2012-02-08 2013-08-15 North Carolina State University Treatment of allergic diseases with recombinant antibodies
US12565524B2 (en) * 2012-05-29 2026-03-03 North Carolina Central University Methods for the production of cytoprotective asialo-erythropoietin in plants and its purification from plant tissues
US20140115728A1 (en) 2012-10-24 2014-04-24 A. Joseph Tector Double knockout (gt/cmah-ko) pigs, organs and tissues
JP7127859B2 (ja) 2016-11-09 2022-08-30 ノース カロライナ ステート ユニバーシティ キメラタンパク質を用いたアレルギー疾患の治療
EP3548612A4 (de) 2016-12-01 2020-04-15 Plantform Corporation Transgene pflanze mit reduzierter fucosyltransferase- und xylosyltransferase-aktivität
JP6934666B2 (ja) * 2018-01-18 2021-09-15 国立研究開発法人産業技術総合研究所 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法
WO2019183437A1 (en) 2018-03-23 2019-09-26 North Carolina State University Methods and compositions for antibody to high affinity receptor for ige
USD1034550S1 (en) * 2022-12-19 2024-07-09 Shenzhen Xunweijia Technology Development Co., Ltd. Microphone
USD1034549S1 (en) * 2022-12-19 2024-07-09 Shenzhen Xunweijia Technology Development Co., Ltd. Microphone
EP4592681A1 (de) 2024-01-29 2025-07-30 HVD Biotech Vertriebsgesellschaft m.b.H. Allergietest

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5455790A (en) 1977-10-05 1979-05-04 Tomoyuki Tajima Production of erythropoetin
JPS5616496A (en) 1979-07-20 1981-02-17 Sumitomo Chem Co Ltd Recovery of erythropoietin
JPS5653696A (en) 1979-10-09 1981-05-13 Ajinomoto Co Inc Isolation of erythropoietin by adsorption
JPS56108798A (en) 1980-02-01 1981-08-28 Green Cross Corp:The Purification of erythropoietin
JPS57149228A (en) 1981-03-11 1982-09-14 Ajinomoto Co Inc Novel erythropoietin and its preparation
JPS57169424A (en) 1981-04-10 1982-10-19 Toyo Shinyaku Kk Preparation of erythropoietin
US4956282A (en) * 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
US5179198A (en) 1988-07-11 1993-01-12 Hidechika Okada Glycoprotein and gene coding therefor
US5959177A (en) 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
US5202422A (en) 1989-10-27 1993-04-13 The Scripps Research Institute Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use
WO1991016449A1 (en) 1990-04-16 1991-10-31 The Trustees Of The University Of Pennsylvania Saccharide compositions, methods and apparatus for their synthesis
FI925745A7 (fi) 1991-04-18 1992-12-17 Toray Industries Interleukiini-6-koostumuksia ja menetelmä niiden valmistamiseksi
US5874271A (en) 1992-08-21 1999-02-23 Takara Shuzo Co., Ltd. Human glycosyltransferase gene, compounds and method for inhibiting cancerous metastasis
FI952574A0 (fi) 1992-11-27 1995-05-26 Ciba Geigy Ag Glykosyylitransferaasiaktiiviset proteiinit
CN1129953A (zh) 1993-07-15 1996-08-28 尼奥斯药品公司 糖组分的合成方法
JP2839232B2 (ja) * 1993-12-24 1998-12-16 理化学研究所 新規糖鎖合成酵素
WO1995018217A1 (en) 1993-12-24 1995-07-06 The Institute Of Physical And Chemical Research Novel sugar-chain synthetase and process for producing the same
JP2854803B2 (ja) * 1994-04-28 1999-02-10 理化学研究所 新規糖鎖合成酵素
US5955647A (en) * 1994-02-03 1999-09-21 The Scripps Research Institute Method for using tobacco mosaic virus to overproduce peptides and proteins
US5723755A (en) * 1995-05-16 1998-03-03 Francis E. Lefaivre Large scale production of human or animal proteins using plant bioreactors
US5939288A (en) 1995-06-07 1999-08-17 Iowa State University Research Foundation, Inc. Plant secretory signal peptides and nectarins
FR2736930B1 (fr) * 1995-07-17 1997-09-19 Biocem Procede de production, par des cellules vegetales, de proteines heminiques, proteines ainsi obtenues et produits contenant ces proteines
WO1997004122A1 (en) 1995-07-20 1997-02-06 Washington State University Research Foundation Production of secreted foreign polypeptides in plant cell culture
US6054304A (en) 1996-01-24 2000-04-25 Toyo Boseki Kabushiki Kaisha α1-6 fucosyltransferase
US7001998B2 (en) 1996-08-02 2006-02-21 The Austin Research Institute Nucleic acids encoding a chimeric glycosyltransferase
AU736993B2 (en) 1997-01-16 2001-08-09 Novo Nordisk A/S Practical in vitro sialylation of recombinant glycoproteins
US6087115A (en) 1997-01-22 2000-07-11 Cornell Research Foundation, Inc. Methods of identifying negative antagonists for G protein coupled receptors
JP3921271B2 (ja) 1997-05-16 2007-05-30 生化学工業株式会社 グルクロン酸転移酵素をコードするｄｎａ
JP4003093B2 (ja) 1997-07-29 2007-11-07 東洋紡績株式会社 糖類の製造方法
WO1999024584A1 (en) 1997-11-12 1999-05-20 Neurotherapeutics Methods for the detection and treatment of disease using a glycosyltransferase
DE19754622A1 (de) 1997-12-09 1999-06-10 Antje Von Dr Schaewen Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität
FR2774379B1 (fr) 1998-01-30 2002-03-29 Groupe Limagrain Holding Procede de production, par des cellules vegetales, d'alpha 1-antitrypsine et de ses variantes, et produits contenant l'alpha-antitrypsine ainsi obtenue
US6096546A (en) 1998-01-30 2000-08-01 Board Of Trustees, Rutgers, The State University Of New Jersey Methods for recovering polypeptides from plants and portions thereof
US5955282A (en) * 1998-04-03 1999-09-21 Incyte Pharmaceuticals, Inc. Human galactosyltransferases
JP4334141B2 (ja) 1998-04-20 2009-09-30 グリカート バイオテクノロジー アクチェンゲゼルシャフト 抗体依存性細胞傷害性を改善するための抗体のグリコシル化操作
IL126967A (en) 1998-11-09 2002-09-12 Lightech Electronics Ind Ltd Electronic transformer for lighting
CA2351022A1 (en) 1998-11-18 2000-05-25 Neose Technologies, Inc. Low cost manufacture of oligosaccharides
PT1137789E (pt) * 1998-12-09 2010-10-21 Phyton Holdings Llc Um método para produzir glicoproteínas possuindo glicosilação de tipo humano
AT408446B (de) 1999-02-18 2001-11-26 Altmann Friedrich Dr Fucosyltransferase-gen
JP2000245470A (ja) 1999-02-26 2000-09-12 Noda Inst For Scient Res 植物細胞間液による外来ポリペプチドの製造方法
EP1159406A4 (de) 1999-03-02 2002-10-30 Human Genome Sciences Inc Menschliche glykosylierungsenzyme
JP2000287692A (ja) 1999-04-09 2000-10-17 Mitsui Chemicals Inc 糖タンパク質の有するｎ−結合型糖鎖の組成中、分岐数が異なる糖鎖の含有割合を制御する方法
AU1090701A (en) 1999-10-15 2001-04-30 Calgene Llc Methods and vectors for site-specific recombination in plant cell plastids
CA2388432A1 (en) * 1999-10-21 2001-04-26 Monsanto Company Post-translational modification of recombinant proteins produced in plants
ES2349427T3 (es) 1999-10-26 2011-01-03 Stichting Dienst Landbouwkundig Onderzoek Glicosilación de tipo mamífero en plantas.
ATE365219T1 (de) 1999-10-26 2007-07-15 Plant Res Int Bv Glykolisierung des säugetiertyps in pflanzen
JP2001546898A (en) 1999-12-21 2003-06-10 Kyowa Hakko Kogyo Kk MODIFIED alpha -1,2-FUCOSYLTRANSFERASE GENE AND PROCESS FOR PRODUCING alpha -1,2-FUCOSYLTRANSFERASE AND FUCOSE-CONTAINING SUGAR CHAIN
FR2803307A1 (fr) 1999-12-30 2001-07-06 Centre Nat Rech Scient Lignees de lymphocytes t cd4 specifiques de type th1 et procede pour leur induction ex vivo
DE60044038D1 (de) 1999-12-30 2010-04-29 Knut Kleesiek Xylosyltransferase und isoformen
AU2001235285A1 (en) 2000-02-24 2001-09-03 University Of Guelph Method of modulating glycosylation pathways
US20020174453A1 (en) * 2001-04-18 2002-11-21 Henry Daniell Production of antibodies in transgenic plastids
AT409381B (de) 2000-03-03 2002-07-25 Gloessl Josef Dr Xylosyltransferase-gen
FR2808286B1 (fr) 2000-04-26 2004-12-17 Agronomique Inst Nat Rech Nouvelle glucosidase i de plante et son application a la production de proteines recombinantes a glycosylation modifiee
AU2001250573A1 (en) 2000-04-28 2001-11-12 Michel Xilinas Treatment of pathological conditions influenced by the action of matrix metalloproteinases (mmps) using phanquinone
NZ522320A (en) 2000-05-12 2007-03-30 Neose Technologies Inc In vitro modification of glycosylation patterns of recombinant glycopeptides
US7029872B2 (en) 2000-06-28 2006-04-18 Glycofi, Inc Methods for producing modified glycoproteins
WO2002007067A1 (en) 2000-07-19 2002-01-24 Digimarc Corporation Print media with embedded messages for controlling printing
TW519716B (en) * 2000-12-19 2003-02-01 Tokyo Electron Ltd Wafer bias drive for a plasma source
CN100385006C (zh) 2001-01-19 2008-04-30 陶氏化学公司 利用植物细胞分泌性生产具有人型糖链的糖蛋白的方法
CN1541059A (zh) 2001-03-06 2004-10-27 �Ϻ���ͨ��ѧ 具有动物型糖链加成功能的植物细胞
ATE467875T1 (de) 2001-06-22 2010-05-15 Siemens Ag Video-rauchdetektionssystem und verfahren zu dessen überprüfung
KR20030072324A (ko) 2001-07-09 2003-09-13 이비덴 가부시키가이샤 세라믹 히터 및 세라믹 접합체
SE519261C2 (sv) 2001-07-17 2003-02-04 Sca Hygiene Prod Ab Absorberande alster
WO2003007861A1 (en) 2001-07-20 2003-01-30 Cutmed Ltd. System for performing a micro-drilling procedure in human or animal and a method for use thereof
EP1423510A4 (de) 2001-08-03 2005-06-01 Glycart Biotechnology Ag Antikörperglykosylierungsvarianten mit erhöhter antikörperabhängiger zellulärer zytotoxizität
US20030175755A1 (en) 2002-03-05 2003-09-18 Yoshihiro Abiko Method of collecting data for estimation of susceptibility to periodontal disease
CA2478294C (en) 2002-03-19 2013-09-03 Plant Research International B.V. Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta (1,4)-n-acetylglucosaminyltransferase iii) expression in plants
CA2923247A1 (en) 2002-03-19 2003-09-25 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
DE10229635C1 (de) 2002-07-02 2003-07-10 Ise Gmbh Überrollschutzsystem für Kraftfahrzeuge
AR042145A1 (es) 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
ES2348857T3 (es) * 2005-07-12 2010-12-03 Greenovation Biotech Gmbh Mejoras en o relacionadas con la produccion de proteinas.
KR101426667B1 (ko) 2007-04-17 2014-08-06 스티칭 디엔스트 랜드보위쿤디그 온데조에크 비-포유동물 글리코실트랜스퍼라제의 발현에 의한 식물에서의 포유동물형 글리코실화

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HK1105785A1 (en) 2008-02-22
DK1772518T3 (da) 2010-11-22
DE60044858D1 (de) 2010-09-30
DK1228231T3 (da) 2007-10-29
EP1228231B1 (de) 2007-06-20
IL212887A0 (en) 2011-07-31
PT1772518E (pt) 2010-10-28
US20080003680A1 (en) 2008-01-03
AU1738401A (en) 2001-05-08
DE60035285D1 (de) 2007-08-02
US8907163B2 (en) 2014-12-09
CA2389217A1 (en) 2001-05-03
EP1772518A3 (de) 2007-04-18
NZ518532A (en) 2004-02-27
US20120237972A1 (en) 2012-09-20
US20110030108A1 (en) 2011-02-03
IL212888A0 (en) 2011-07-31
EP1772518A2 (de) 2007-04-11
IL212888A (en) 2017-12-31
IL212889A0 (en) 2011-07-31
US7781647B2 (en) 2010-08-24
WO2001031045A1 (en) 2001-05-03
IL204883A (en) 2012-05-31
BR0015031A (pt) 2002-06-18
PT1228231E (pt) 2007-09-25
US8193415B2 (en) 2012-06-05
IL149271A0 (en) 2002-11-10
ATE478150T1 (de) 2010-09-15
IL149271A (en) 2010-11-30
TR200201121T2 (tr) 2003-01-21
CA2925231A1 (en) 2001-05-03
EP1228231A1 (de) 2002-08-07
JP2003512076A (ja) 2003-04-02
EP2251426A1 (de) 2010-11-17
CA2389217C (en) 2016-12-06
ES2288882T3 (es) 2008-02-01
BRPI0015031B1 (pt) 2017-05-30
EP1772518B1 (de) 2010-08-18
JP4890712B2 (ja) 2012-03-07
MXPA02004142A (es) 2003-08-20

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