ATE365538T1 - O/w emulsion - Google Patents

O/w emulsion

Info

Publication number
ATE365538T1
ATE365538T1 AT01931897T AT01931897T ATE365538T1 AT E365538 T1 ATE365538 T1 AT E365538T1 AT 01931897 T AT01931897 T AT 01931897T AT 01931897 T AT01931897 T AT 01931897T AT E365538 T1 ATE365538 T1 AT E365538T1
Authority
AT
Austria
Prior art keywords
compositions
water
parenteral administration
emulsion
propofol
Prior art date
Application number
AT01931897T
Other languages
English (en)
Inventor
David Goodale
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE365538T1 publication Critical patent/ATE365538T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Edible Oils And Fats (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
AT01931897T 2000-05-25 2001-05-22 O/w emulsion ATE365538T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0012597.1A GB0012597D0 (en) 2000-05-25 2000-05-25 Formulation

Publications (1)

Publication Number Publication Date
ATE365538T1 true ATE365538T1 (de) 2007-07-15

Family

ID=9892262

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01931897T ATE365538T1 (de) 2000-05-25 2001-05-22 O/w emulsion

Country Status (18)

Country Link
US (3) US20030144356A1 (de)
EP (1) EP1289503B1 (de)
JP (1) JP2003535057A (de)
KR (1) KR20030009501A (de)
CN (1) CN1430503A (de)
AT (1) ATE365538T1 (de)
AU (2) AU2001258588B2 (de)
BR (1) BR0111136A (de)
CA (1) CA2407764A1 (de)
DE (1) DE60129134T2 (de)
ES (1) ES2287128T3 (de)
GB (1) GB0012597D0 (de)
IL (1) IL152773A0 (de)
MX (1) MXPA02011532A (de)
NO (1) NO20025629L (de)
NZ (1) NZ522365A (de)
WO (1) WO2001089474A2 (de)
ZA (1) ZA200208853B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1166368C (zh) * 2003-02-26 2004-09-15 刘威 海狗油脂肪乳注射液、其制备方法及其在制备静脉注射剂中的应用
US7780873B2 (en) * 2004-02-23 2010-08-24 Texas A&M University System Bioactive complexes compositions and methods of use thereof
CA2572344A1 (en) * 2004-07-01 2006-01-19 Schepens Eye Research Compositions and methods for treating eye disorders and conditions
CN100358513C (zh) * 2005-04-07 2008-01-02 常州市第四制药厂有限公司 一种丙泊酚注射液的制备工艺
BRPI0614084A2 (pt) * 2005-08-05 2011-03-09 Bharat Serums & Vaccines Ltd composição estável de emulsão de óleo-em-água de propofol, administrável por via intranovesa; e processo de preparação de uma composição
US20070149617A1 (en) * 2005-11-14 2007-06-28 Deckelbaum Richard J Use of an omega-3 lipid-based emulsion following ischemic injury to provide protection and recovery in human organs
WO2008036353A2 (en) * 2006-09-19 2008-03-27 The Trustees Of Columbia University In The City Of New York Omega-3 diglyceride emulsions
CN101411685B (zh) * 2007-10-19 2011-04-20 上海医药工业研究院 一种静脉麻醉药2,6-二异丙基苯酚微乳组合物及其制备方法
US9034389B2 (en) 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US20110071090A1 (en) * 2009-03-11 2011-03-24 Stable Solutions Llc Method of mitigating adverse drug events using omega-3-fatty acids as a parenteral therapeutic drug vehicle
US8241672B2 (en) * 2009-03-11 2012-08-14 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US8993625B2 (en) 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
PL2437762T3 (pl) 2009-06-05 2018-01-31 Allergan Inc Sztuczne łzy i ich zastosowania terapeutyczne
WO2011047091A1 (en) * 2009-10-13 2011-04-21 Martek Biosciences Corporation Methods for treating traumatic brain injury
WO2011103514A1 (en) * 2010-02-18 2011-08-25 Martek Biosciences Corporation Dha triglyceride emulsions
US20110200645A1 (en) * 2010-02-18 2011-08-18 Martek Biosciences Corporation DHA Free Fatty Acid Emulsions
WO2011103510A1 (en) * 2010-02-18 2011-08-25 Martek Biosciences Corporation Dha ester emulsions
EP2560633B8 (de) * 2010-04-23 2020-08-12 The Government of the United States, as represented by The Secretary of the Army Intravenöse omega-3-fettsäuren-zusammensetzungen sowie verwendungsverfahren dafür
US11236351B2 (en) 2010-05-17 2022-02-01 Dow Agrosciences Llc Production of DHA and other LC PUFAs in plants
KR20130117658A (ko) * 2010-05-25 2013-10-28 에릭 쿠르츠 지방산의 안정한 제형
NZ606591A (en) * 2010-07-06 2015-02-27 Novartis Ag Cationic oil-in-water emulsions
BR112013008601B1 (pt) 2010-10-12 2020-03-31 Chiesi Farmaceutici S.P.A. Formulações de emulsão de clevidipina contendo agentes antimicrobianos
US8658676B2 (en) 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
US20120251685A1 (en) * 2011-04-04 2012-10-04 Martek Biosciences Corporation Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same
RS56394B1 (sr) * 2011-06-15 2017-12-29 Stable Solutions Llc Terapeutska primena parenteralnog kril ulja
US10052352B2 (en) 2011-06-15 2018-08-21 Stable Solutions Llc Therapeutic application of parenteral krill oil
TW201307553A (zh) * 2011-07-26 2013-02-16 Dow Agrosciences Llc 在植物中生產二十二碳六烯酸（ｄｈａ）及其他長鏈多元不飽和脂肪酸（ｌｃ－ｐｕｆａ）之技術
CN102366404B (zh) * 2011-10-20 2015-10-07 四川百利药业有限责任公司 一种丙泊酚中/长链脂肪乳剂
WO2014033751A2 (en) * 2012-08-16 2014-03-06 Emcure Pharmaceuticals Limited Pharmaceutical composition of propofol
CN105263321B (zh) 2013-03-28 2018-07-27 哥伦比亚大学纽约管理委员会 用omega-3甘油酯再灌注促进对用于移植的供体器官的保护
ES2607715B1 (es) * 2015-10-01 2018-01-17 Solutex Na, Lcc Proceso para la preparación y estabilización de emulsiones con omega-3 mediante redes cristalinas isométricas de derivados de celulosa

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5478414A (en) * 1992-01-31 1995-12-26 Aluminum Company Of America Reflective aluminum strip, protected with fluoropolymer coating and a laminate of the strip with a thermoplastic polymer
US5637404A (en) * 1992-01-31 1997-06-10 Aluminum Company Of America Reflective aluminum strip
CA2182575C (en) * 1994-02-04 2000-11-28 Anders Carlsson Oil-in-water emulsions
GB9405593D0 (en) * 1994-03-22 1994-05-11 Zeneca Ltd Pharmaceutical compositions
EP1105096B1 (de) * 1998-08-19 2003-10-29 Skyepharma Canada Inc. Injizierbare wässerige propofoldispersionen
US6140374A (en) * 1998-10-23 2000-10-31 Abbott Laboratories Propofol composition
US6582723B2 (en) * 2001-05-03 2003-06-24 Wayne F. Gorsek Cancer immune composition for prevention and treatment of individuals

Also Published As

Publication number Publication date
EP1289503A2 (de) 2003-03-12
KR20030009501A (ko) 2003-01-29
MXPA02011532A (es) 2003-04-25
GB0012597D0 (en) 2000-07-12
NZ522365A (en) 2004-09-24
WO2001089474A3 (en) 2002-03-07
US20060257433A1 (en) 2006-11-16
ES2287128T3 (es) 2007-12-16
CN1430503A (zh) 2003-07-16
US20080312338A1 (en) 2008-12-18
CA2407764A1 (en) 2001-11-29
NO20025629D0 (no) 2002-11-22
ZA200208853B (en) 2004-02-19
AU5858801A (en) 2001-12-03
EP1289503B1 (de) 2007-06-27
BR0111136A (pt) 2003-04-08
AU2001258588B2 (en) 2005-05-19
IL152773A0 (en) 2003-06-24
JP2003535057A (ja) 2003-11-25
NO20025629L (no) 2003-01-08
DE60129134D1 (en) 2007-08-09
DE60129134T2 (de) 2008-02-28
US20030144356A1 (en) 2003-07-31
WO2001089474A2 (en) 2001-11-29

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