ATE365538T1 - O/w emulsion - Google Patents

O/w emulsion

Info

Publication number
ATE365538T1
ATE365538T1 AT01931897T AT01931897T ATE365538T1 AT E365538 T1 ATE365538 T1 AT E365538T1 AT 01931897 T AT01931897 T AT 01931897T AT 01931897 T AT01931897 T AT 01931897T AT E365538 T1 ATE365538 T1 AT E365538T1
Authority
AT
Austria
Prior art keywords
compositions
water
parenteral administration
emulsion
propofol
Prior art date
Application number
AT01931897T
Other languages
English (en)
Inventor
David Goodale
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE365538T1 publication Critical patent/ATE365538T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Anesthesiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Colloid Chemistry (AREA)
  • Edible Oils And Fats (AREA)
AT01931897T 2000-05-25 2001-05-22 O/w emulsion ATE365538T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0012597.1A GB0012597D0 (en) 2000-05-25 2000-05-25 Formulation

Publications (1)

Publication Number Publication Date
ATE365538T1 true ATE365538T1 (de) 2007-07-15

Family

ID=9892262

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01931897T ATE365538T1 (de) 2000-05-25 2001-05-22 O/w emulsion

Country Status (18)

Country Link
US (3) US20030144356A1 (de)
EP (1) EP1289503B1 (de)
JP (1) JP2003535057A (de)
KR (1) KR20030009501A (de)
CN (1) CN1430503A (de)
AT (1) ATE365538T1 (de)
AU (2) AU2001258588B2 (de)
BR (1) BR0111136A (de)
CA (1) CA2407764A1 (de)
DE (1) DE60129134T2 (de)
ES (1) ES2287128T3 (de)
GB (1) GB0012597D0 (de)
IL (1) IL152773A0 (de)
MX (1) MXPA02011532A (de)
NO (1) NO20025629L (de)
NZ (1) NZ522365A (de)
WO (1) WO2001089474A2 (de)
ZA (1) ZA200208853B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1166368C (zh) * 2003-02-26 2004-09-15 刘威 海狗油脂肪乳注射液、其制备方法及其在制备静脉注射剂中的应用
US7780873B2 (en) * 2004-02-23 2010-08-24 Texas A&M University System Bioactive complexes compositions and methods of use thereof
AU2005262392A1 (en) * 2004-07-01 2006-01-19 Johnson & Johnson Vision Care, Inc. Compositions and methods for treating eye disorders and conditions
CN100358513C (zh) * 2005-04-07 2008-01-02 常州市第四制药厂有限公司 一种丙泊酚注射液的制备工艺
ATE420625T1 (de) * 2005-08-05 2009-01-15 Bharat Serums & Vaccines Ltd Intravenöse propofol-emulsionszusammensetzungen mit konservierendem effekt
US20070149617A1 (en) * 2005-11-14 2007-06-28 Deckelbaum Richard J Use of an omega-3 lipid-based emulsion following ischemic injury to provide protection and recovery in human organs
WO2008036353A2 (en) * 2006-09-19 2008-03-27 The Trustees Of Columbia University In The City Of New York Omega-3 diglyceride emulsions
CN101411685B (zh) * 2007-10-19 2011-04-20 上海医药工业研究院 一种静脉麻醉药2,6-二异丙基苯酚微乳组合物及其制备方法
US9034389B2 (en) 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US8993625B2 (en) 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
US20110071090A1 (en) * 2009-03-11 2011-03-24 Stable Solutions Llc Method of mitigating adverse drug events using omega-3-fatty acids as a parenteral therapeutic drug vehicle
US8241672B2 (en) * 2009-03-11 2012-08-14 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
MX358504B (es) 2009-06-05 2018-08-21 Allergan Inc Lagrimas artificiales y usos terapeuticos.
WO2011047091A1 (en) * 2009-10-13 2011-04-21 Martek Biosciences Corporation Methods for treating traumatic brain injury
US20110206741A1 (en) * 2010-02-18 2011-08-25 Martek Biosciences Corporation DHA Triglyceride Emulsions
US20110200645A1 (en) * 2010-02-18 2011-08-18 Martek Biosciences Corporation DHA Free Fatty Acid Emulsions
US20110200644A1 (en) * 2010-02-18 2011-08-18 Martek Biosciences Corporation DHA Ester Emulsions
WO2011133841A2 (en) * 2010-04-23 2011-10-27 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Intravenous omega-3 fatty acid compositions & method of use
US11236351B2 (en) 2010-05-17 2022-02-01 Dow Agrosciences Llc Production of DHA and other LC PUFAs in plants
JP2013526605A (ja) * 2010-05-25 2013-06-24 エリック カーツ, 脂肪酸の安定な処方物
NZ606591A (en) * 2010-07-06 2015-02-27 Novartis Ag Cationic oil-in-water emulsions
PL2627173T5 (pl) 2010-10-12 2019-11-29 Chiesi Farm Spa Formulacje emulsyjne klewidypiny zawierające środki przeciw mikrobom
US8658676B2 (en) 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
US20120251685A1 (en) * 2011-04-04 2012-10-04 Martek Biosciences Corporation Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same
US10052352B2 (en) 2011-06-15 2018-08-21 Stable Solutions Llc Therapeutic application of parenteral krill oil
EP2720701B1 (de) * 2011-06-15 2017-08-09 Stable Solutions Llc Therapeutische parenterale anwendung von krillöl
TW201307553A (zh) 2011-07-26 2013-02-16 Dow Agrosciences Llc 在植物中生產二十二碳六烯酸(dha)及其他長鏈多元不飽和脂肪酸(lc-pufa)之技術
CN102366404B (zh) * 2011-10-20 2015-10-07 四川百利药业有限责任公司 一种丙泊酚中/长链脂肪乳剂
WO2014033751A2 (en) * 2012-08-16 2014-03-06 Emcure Pharmaceuticals Limited Pharmaceutical composition of propofol
HK1221119A1 (zh) 2013-03-28 2017-05-26 The Trustees Of Columbia University In The City Of New York 用omega-3甘油酯再灌注促进对用於移植的供体器官的保护
ES2607715B1 (es) * 2015-10-01 2018-01-17 Solutex Na, Lcc Proceso para la preparación y estabilización de emulsiones con omega-3 mediante redes cristalinas isométricas de derivados de celulosa

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5478414A (en) * 1992-01-31 1995-12-26 Aluminum Company Of America Reflective aluminum strip, protected with fluoropolymer coating and a laminate of the strip with a thermoplastic polymer
US5637404A (en) * 1992-01-31 1997-06-10 Aluminum Company Of America Reflective aluminum strip
WO1995020943A1 (en) * 1994-02-04 1995-08-10 Scotia Lipidteknik Ab Oil-in-water emulsions
GB9405593D0 (en) * 1994-03-22 1994-05-11 Zeneca Ltd Pharmaceutical compositions
DE69912441T2 (de) * 1998-08-19 2004-08-19 Skyepharma Canada Inc., Verdun Injizierbare wässerige propofoldispersionen
US6140374A (en) * 1998-10-23 2000-10-31 Abbott Laboratories Propofol composition
US6582723B2 (en) * 2001-05-03 2003-06-24 Wayne F. Gorsek Cancer immune composition for prevention and treatment of individuals

Also Published As

Publication number Publication date
JP2003535057A (ja) 2003-11-25
AU5858801A (en) 2001-12-03
BR0111136A (pt) 2003-04-08
WO2001089474A2 (en) 2001-11-29
WO2001089474A3 (en) 2002-03-07
GB0012597D0 (en) 2000-07-12
US20060257433A1 (en) 2006-11-16
CA2407764A1 (en) 2001-11-29
KR20030009501A (ko) 2003-01-29
NO20025629L (no) 2003-01-08
ZA200208853B (en) 2004-02-19
US20080312338A1 (en) 2008-12-18
IL152773A0 (en) 2003-06-24
EP1289503A2 (de) 2003-03-12
CN1430503A (zh) 2003-07-16
EP1289503B1 (de) 2007-06-27
MXPA02011532A (es) 2003-04-25
NZ522365A (en) 2004-09-24
ES2287128T3 (es) 2007-12-16
DE60129134D1 (en) 2007-08-09
DE60129134T2 (de) 2008-02-28
US20030144356A1 (en) 2003-07-31
NO20025629D0 (no) 2002-11-22
AU2001258588B2 (en) 2005-05-19

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