ATE366746T1 - Gegen das semp1-protein gerichtete antikörper, verfahren zu deren herstellung, und deren anwendungen - Google Patents

Gegen das semp1-protein gerichtete antikörper, verfahren zu deren herstellung, und deren anwendungen

Info

Publication number
ATE366746T1
ATE366746T1 AT01114743T AT01114743T ATE366746T1 AT E366746 T1 ATE366746 T1 AT E366746T1 AT 01114743 T AT01114743 T AT 01114743T AT 01114743 T AT01114743 T AT 01114743T AT E366746 T1 ATE366746 T1 AT E366746T1
Authority
AT
Austria
Prior art keywords
semp1
protein
applications
production
dsm
Prior art date
Application number
AT01114743T
Other languages
English (en)
Inventor
Thorsten Hoevel
Stefan Koch
Manfred Kubbies
Olaf Mundigl
Petra Rueger
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26071070&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE366746(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP00113344A external-priority patent/EP1167387A1/de
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE366746T1 publication Critical patent/ATE366746T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT01114743T 2000-06-23 2001-06-22 Gegen das semp1-protein gerichtete antikörper, verfahren zu deren herstellung, und deren anwendungen ATE366746T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00113344A EP1167387A1 (de) 2000-06-23 2000-06-23 Anti-SEMP1-Antikörper, Verfahren zu deren Herstellung, und deren Anwendungen
EP01107799 2001-04-05

Publications (1)

Publication Number Publication Date
ATE366746T1 true ATE366746T1 (de) 2007-08-15

Family

ID=26071070

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01114743T ATE366746T1 (de) 2000-06-23 2001-06-22 Gegen das semp1-protein gerichtete antikörper, verfahren zu deren herstellung, und deren anwendungen

Country Status (10)

Country Link
US (1) US6627439B2 (de)
EP (1) EP1167389B1 (de)
JP (1) JP3542784B2 (de)
AT (1) ATE366746T1 (de)
AU (1) AU750296B2 (de)
CA (1) CA2348026C (de)
DE (1) DE60129278T2 (de)
DK (1) DK1167389T3 (de)
ES (1) ES2290072T3 (de)
PT (1) PT1167389E (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040033228A1 (en) 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
EP2311980A1 (de) * 2002-08-20 2011-04-20 Millennium Pharmaceuticals, Inc. Zusammensetzungen, Kits und Verfahren zur Identifizierung, Beurteilung, Vorbeugung und Therapie von Gebärmutterhalskrebs
WO2007130646A2 (en) * 2006-05-04 2007-11-15 The Rockefeller University Hcv coreceptor and methods of use thereof
BRPI0919065B1 (pt) * 2008-09-25 2021-09-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Anticorpos monoclonais anti-claudin-i para a inibição de infecção por vírus de hepatite c
CA2800734A1 (en) 2010-05-25 2011-12-01 Universite De Strasbourg Combination of anti-envelope antibodies and anti-receptor antibodies for the treatment and prevention of hcv infection
WO2013024155A1 (en) 2011-08-17 2013-02-21 Inserm (Institut National De La Sante Et De La Recherche Medicale) Combinations of anti-hcv-entry factor antibodies and direct acting antivirals for the treatment and the prevention of hcv infection
WO2013024157A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of host targeting agents for the treatment and the prevention of hcv infection
WO2013024156A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
JP6393875B2 (ja) * 2013-02-28 2018-09-26 公益財団法人ヒューマンサイエンス振興財団 抗体
JP2016525558A (ja) * 2013-08-02 2016-08-25 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 結腸直腸ガンの処置に使用するための抗クローディン１抗体
JP2016528221A (ja) * 2013-08-02 2016-09-15 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 抗クローディン１抗体およびその使用
EP3070103A1 (de) 2015-03-19 2016-09-21 Institut Hospitalier Universitaire De Strasbourg Monoklonale anti-claudin 1-antikörper zur vorbeugung und behandlung von hepatozellulärem karzinom
EP3821946A1 (de) 2019-11-12 2021-05-19 Université de Strasbourg Monoklonale anti-claudin-1-antikörper zur prävention und behandlung von fibrotischen erkrankungen
CN113455494A (zh) * 2021-05-12 2021-10-01 南京生航生物技术有限公司 一种无血清细胞冻存液及制备方法和制备装置
CN119156403A (zh) 2022-03-08 2024-12-17 阿伦蒂斯治疗股份公司 抗紧密连接蛋白-1抗体增加t细胞可用性的用途
JP2025520129A (ja) 2022-06-01 2025-07-01 アレンティス・セラピューティクス・アクチェンゲゼルシャフト 胆管癌を治療するための抗クローディン－１抗体の使用
EP4532027A1 (de) 2022-06-01 2025-04-09 Alentis Therapeutics AG Verwendung von anti-claudin-1-antikörpern zur behandlung von cholangiopathien
CN120379691A (zh) 2022-09-30 2025-07-25 爱兰蒂斯疗法股份公司 耐药性肝细胞癌的治疗
WO2024194471A1 (en) 2023-03-23 2024-09-26 Alentis Therapeutics Ag Biomarker for cancer treatment using anti-claudin-1 antibodies
WO2025224337A1 (en) 2024-04-26 2025-10-30 Alentis Therapeutics Ag Anti-cldn1 antibody-drug conjugates comprising exatecan and methods of use thereof
WO2025224335A1 (en) 2024-04-26 2025-10-30 Alentis Therapeutics Ag Anti-cldn1 antibody-drug conjugates comprising mmae and methods of use thereof
WO2026057723A1 (en) 2024-09-12 2026-03-19 Alentis Therapeutics Ag Claudin-1/egfr bispecific antibodies for targeted degradation
WO2026057702A1 (en) 2024-09-12 2026-03-19 Alentis Therapeutics Ag Claudin-1/egfr bispecific antibodies

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6416974B1 (en) 1997-08-06 2002-07-09 Millennium Pharmaceuticals, Inc. Tango 71 nucleic acids
WO1999007893A1 (en) 1997-08-08 1999-02-18 University Of Washington ISOLATION OF A NOVEL SENESCENCE-FACTOR GENE, p23
JP2002519029A (ja) 1998-06-29 2002-07-02 インサイト・ファーマスーティカルズ・インコーポレイテッド アポトーシス関連分子

Also Published As

Publication number Publication date
PT1167389E (pt) 2007-09-27
DE60129278T2 (de) 2008-03-20
EP1167389B1 (de) 2007-07-11
AU750296B2 (en) 2002-07-11
JP3542784B2 (ja) 2004-07-14
US20020150574A1 (en) 2002-10-17
US6627439B2 (en) 2003-09-30
CA2348026A1 (en) 2001-12-23
ES2290072T3 (es) 2008-02-16
DK1167389T3 (da) 2007-11-12
DE60129278D1 (de) 2007-08-23
JP2002332300A (ja) 2002-11-22
EP1167389A1 (de) 2002-01-02
AU5007901A (en) 2002-01-03
CA2348026C (en) 2005-06-07

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