ATE370939T1 - Verfahren zur herstellung von tocopherylacylaten - Google Patents

Verfahren zur herstellung von tocopherylacylaten

Info

Publication number
ATE370939T1
ATE370939T1 AT05736077T AT05736077T ATE370939T1 AT E370939 T1 ATE370939 T1 AT E370939T1 AT 05736077 T AT05736077 T AT 05736077T AT 05736077 T AT05736077 T AT 05736077T AT E370939 T1 ATE370939 T1 AT E370939T1
Authority
AT
Austria
Prior art keywords
tocopherylacylates
producing
tocopherols
acylation
tocopherol
Prior art date
Application number
AT05736077T
Other languages
English (en)
Inventor
Werner Bonrath
Lisa Giraudi
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Application granted granted Critical
Publication of ATE370939T1 publication Critical patent/ATE370939T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G13/00—Vitamins of unknown constitution

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Plant Substances (AREA)
AT05736077T 2004-04-26 2005-04-18 Verfahren zur herstellung von tocopherylacylaten ATE370939T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04009816 2004-04-26

Publications (1)

Publication Number Publication Date
ATE370939T1 true ATE370939T1 (de) 2007-09-15

Family

ID=34965832

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05736077T ATE370939T1 (de) 2004-04-26 2005-04-18 Verfahren zur herstellung von tocopherylacylaten

Country Status (9)

Country Link
US (1) US7435836B2 (de)
EP (1) EP1740567B1 (de)
JP (1) JP4874236B2 (de)
KR (1) KR101174174B1 (de)
CN (1) CN1946706B (de)
AT (1) ATE370939T1 (de)
DE (1) DE602005002136T2 (de)
TW (1) TWI347319B (de)
WO (1) WO2005103026A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008077543A1 (en) 2006-12-27 2008-07-03 Dsm Ip Assets B.V. Process for the acylation of organic hydroxy compounds
US8796809B2 (en) 2008-09-08 2014-08-05 Cree, Inc. Varactor diode with doped voltage blocking layer
EP3801496A4 (de) 2018-06-05 2022-07-06 Flagship Pioneering Innovations V, Inc. Wirkstoffe und verfahren zu ihrer verwendung für die behandlung von stoffwechselerkrankungen und nichtalkoholischer fettleber
CN112368258B (zh) * 2018-07-02 2023-10-27 帝斯曼知识产权资产管理有限公司 在仲羟基及其催化剂的存在下选择性酰化伯羟基的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4955633A (de) * 1972-10-12 1974-05-30
DE4243464A1 (de) * 1992-12-22 1994-06-23 Basf Ag Verfahren zur Herstellung von alpha-Tocopherol und alpha-Tocopherylacetat in flüssigem oder überkritischem Kohlendioxid
WO1997028151A1 (de) * 1996-01-29 1997-08-07 Basf Aktiengesellschaft VERFAHREN ZUR HERSTELLUNG VON DL-α-TOCOPHEROL ODER DL-α-TOCOPHERYLACETAT
DE19603142A1 (de) * 1996-01-29 1997-07-31 Basf Ag Verfahren zur Herstellung von dl-alpha-Tocopherol oder dl-alpha-Tocopherylacetat
DE10011402A1 (de) * 2000-03-09 2001-09-13 Degussa Verfahren zur Herstellung von alpha-Tocopherolestern
WO2002042286A1 (de) * 2000-11-22 2002-05-30 Basf Aktiengesellschaft Verfahren zur kontinuierlichen acylierung von chromanolesterderivaten

Also Published As

Publication number Publication date
US7435836B2 (en) 2008-10-14
WO2005103026A1 (en) 2005-11-03
KR101174174B1 (ko) 2012-08-14
JP2007534713A (ja) 2007-11-29
DE602005002136D1 (de) 2007-10-04
CN1946706A (zh) 2007-04-11
TWI347319B (en) 2011-08-21
CN1946706B (zh) 2012-03-21
US20070225509A1 (en) 2007-09-27
EP1740567B1 (de) 2007-08-22
KR20070015550A (ko) 2007-02-05
TW200538448A (en) 2005-12-01
EP1740567A1 (de) 2007-01-10
JP4874236B2 (ja) 2012-02-15
DE602005002136T2 (de) 2008-05-21

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