ATE370940T1 - Verfahren zur herstellung von (s)- glyceraldehydacetonid - Google Patents

Verfahren zur herstellung von (s)- glyceraldehydacetonid

Info

Publication number: ATE370940T1
Authority: AT; Austria
Prior art keywords: sub; isopropylidene; salt; acid; hypochlorite
Prior art date: 2003-10-07

Application number

AT04790256T

Other languages

English (en)

Inventor

Peter Jan Leonard M Quaedflieg

Franciscus Alphons Mari Lommen

Robert Jan Vijn

Van Boxtel

Original Assignee

Dsm Ip Assets Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-10-07

Filing date

2004-10-07

Publication date

2007-09-15

2004-10-07 Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv

2007-09-15 Application granted granted Critical

2007-09-15 Publication of ATE370940T1 publication Critical patent/ATE370940T1/de

Links

238000004519 manufacturing process Methods 0.000 title 1
WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical compound Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 abstract 6
150000003839 salts Chemical class 0.000 abstract 5
239000007864 aqueous solution Substances 0.000 abstract 3
229940056902 l- threonic acid Drugs 0.000 abstract 3
POXUQBFHDHCZAD-UHFFFAOYSA-N 2-(2,2-dimethyl-1,3-dioxolan-4-yl)-3,4-dihydroxy-2h-furan-5-one Chemical compound O1C(C)(C)OCC1C1C(O)=C(O)C(=O)O1 POXUQBFHDHCZAD-UHFFFAOYSA-N 0.000 abstract 2
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
239000000243 solution Substances 0.000 abstract 2
YSGPYVWACGYQDJ-RXMQYKEDSA-N (4s)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde Chemical compound CC1(C)OC[C@@H](C=O)O1 YSGPYVWACGYQDJ-RXMQYKEDSA-N 0.000 abstract 1
QWOJMRHUQHTCJG-UHFFFAOYSA-N CC([CH2-])=O Chemical compound CC([CH2-])=O QWOJMRHUQHTCJG-UHFFFAOYSA-N 0.000 abstract 1
102000016938 Catalase Human genes 0.000 abstract 1
108010053835 Catalase Proteins 0.000 abstract 1
239000002211 L-ascorbic acid Substances 0.000 abstract 1
235000000069 L-ascorbic acid Nutrition 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000003377 acid catalyst Substances 0.000 abstract 1
229960005070 ascorbic acid Drugs 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Furan Compounds (AREA)

AT04790256T 2003-10-07 2004-10-07 Verfahren zur herstellung von (s)- glyceraldehydacetonid ATE370940T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP03078130		2003-10-07

Publications (1)

Publication Number	Publication Date
ATE370940T1 true ATE370940T1 (de)	2007-09-15

Family

ID=34442982

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04790256T ATE370940T1 (de)	2003-10-07	2004-10-07	Verfahren zur herstellung von (s)- glyceraldehydacetonid

Country Status (9)

Country	Link
US (1)	US7361775B2 (de)
EP (1)	EP1673364B1 (de)
JP (1)	JP2007507461A (de)
CN (1)	CN1863787A (de)
AT (1)	ATE370940T1 (de)
CA (1)	CA2541491A1 (de)
DE (1)	DE602004008496T2 (de)
ES (1)	ES2290770T3 (de)
WO (1)	WO2005037819A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2403220B (en) *	2003-06-12	2005-10-19	Mitsui Chemicals Inc	Production of aldoses
US8251944B2 (en) *	2006-03-29	2012-08-28	Novartis Ag	Surgical system having a cassette with an acoustic coupling
US8343100B2 (en)	2006-03-29	2013-01-01	Novartis Ag	Surgical system having a non-invasive flow sensor
US8006570B2 (en) *	2006-03-29	2011-08-30	Alcon, Inc.	Non-invasive flow measurement
WO2011056929A1 (en)	2009-11-04	2011-05-12	Massachusetts Institute Of Technology	Continuous flow synthesis of amino alcohols using microreactors
WO2011109276A1 (en)	2010-03-01	2011-09-09	Massachussets Institute Of Technology	Epoxidation catalysts
CN104230877B (zh) *	2013-06-08	2016-01-27	重庆圣华曦药业股份有限公司	L-（s）-甘油醛缩丙酮的制备方法及其在达芦那韦侧链合成中的应用
CN108610322B (zh) *	2018-04-21	2020-04-07	江苏八巨药业有限公司	一种r-甘油醛缩丙酮的制备方法
CN108686682B (zh) *	2018-05-16	2020-08-25	扬州工业职业技术学院	一种绿色氧化合成甘油醛的方法
CN111732562A (zh) *	2020-06-29	2020-10-02	苏州华鑫医药科技有限公司	一种抗肿瘤药物盐酸吉西他滨中间体的制备方法
CN112079891A (zh) *	2020-09-17	2020-12-15	苏州华鑫医药科技有限公司	一种抗肿瘤药物盐酸吉西他滨的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6094977A (ja) *	1983-10-28	1985-05-28	Takeda Chem Ind Ltd	（ｓ）−グリセルアルデヒドアセトニドの製造法

2004
- 2004-10-07 ES ES04790256T patent/ES2290770T3/es not_active Expired - Lifetime
- 2004-10-07 US US10/574,693 patent/US7361775B2/en not_active Expired - Fee Related
- 2004-10-07 EP EP04790256A patent/EP1673364B1/de not_active Expired - Lifetime
- 2004-10-07 WO PCT/EP2004/011343 patent/WO2005037819A1/en not_active Ceased
- 2004-10-07 CA CA002541491A patent/CA2541491A1/en not_active Abandoned
- 2004-10-07 DE DE602004008496T patent/DE602004008496T2/de not_active Expired - Fee Related
- 2004-10-07 AT AT04790256T patent/ATE370940T1/de not_active IP Right Cessation
- 2004-10-07 JP JP2006530134A patent/JP2007507461A/ja not_active Withdrawn
- 2004-10-07 CN CNA2004800291410A patent/CN1863787A/zh active Pending

Also Published As

Publication number	Publication date
US20070073068A1 (en)	2007-03-29
US7361775B2 (en)	2008-04-22
DE602004008496T2 (de)	2008-05-15
DE602004008496D1 (de)	2007-10-04
JP2007507461A (ja)	2007-03-29
ES2290770T3 (es)	2008-02-16
EP1673364B1 (de)	2007-08-22
EP1673364A1 (de)	2006-06-28
WO2005037819A1 (en)	2005-04-28
CN1863787A (zh)	2006-11-15
CA2541491A1 (en)	2005-04-28

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Legal Events

Date

Code

Title

Description

2008-01-15

UEP

Publication of translation of european patent specification

Ref document number: 1673364

Country of ref document: EP

2010-07-15

REN

Ceased due to non-payment of the annual fee