ATE371730T1 - Detektionsverfahren umfassend die verwendung von polypeptiden mit einem coiled-coil und einer additionsstelle - Google Patents
Detektionsverfahren umfassend die verwendung von polypeptiden mit einem coiled-coil und einer additionsstelleInfo
- Publication number
- ATE371730T1 ATE371730T1 AT98940391T AT98940391T ATE371730T1 AT E371730 T1 ATE371730 T1 AT E371730T1 AT 98940391 T AT98940391 T AT 98940391T AT 98940391 T AT98940391 T AT 98940391T AT E371730 T1 ATE371730 T1 AT E371730T1
- Authority
- AT
- Austria
- Prior art keywords
- polypeptide
- polypeptides
- methods include
- detection methods
- coiled coil
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 7
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- 238000001514 detection method Methods 0.000 title abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
- C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/04—Fusion polypeptide containing a localisation/targetting motif containing an ER retention signal such as a C-terminal HDEL motif
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
- C07K2319/91—Fusion polypeptide containing a motif for post-translational modification containing a motif for glycosylation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Mycology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Enzymes And Modification Thereof (AREA)
- Polarising Elements (AREA)
- Inspection Of Paper Currency And Valuable Securities (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9718358.6A GB9718358D0 (en) | 1997-08-30 | 1997-08-30 | Chemical modification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE371730T1 true ATE371730T1 (de) | 2007-09-15 |
Family
ID=10818247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98940391T ATE371730T1 (de) | 1997-08-30 | 1998-09-01 | Detektionsverfahren umfassend die verwendung von polypeptiden mit einem coiled-coil und einer additionsstelle |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20030027220A1 (de) |
| EP (1) | EP1007653B1 (de) |
| JP (1) | JP2001514849A (de) |
| AT (1) | ATE371730T1 (de) |
| AU (1) | AU8872798A (de) |
| CA (1) | CA2302394A1 (de) |
| DE (1) | DE69838333T2 (de) |
| GB (2) | GB9718358D0 (de) |
| IL (1) | IL134179A0 (de) |
| NO (1) | NO20000901L (de) |
| WO (1) | WO1999011774A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7632651B2 (en) | 1997-09-15 | 2009-12-15 | Mds Analytical Technologies (Us) Inc. | Molecular modification assays |
| US7070921B2 (en) | 2000-04-28 | 2006-07-04 | Molecular Devices Corporation | Molecular modification assays |
| US6982431B2 (en) | 1998-08-31 | 2006-01-03 | Molecular Devices Corporation | Sample analysis systems |
| GB9904398D0 (en) * | 1999-02-25 | 1999-04-21 | Fluorescience Ltd | High throughput assay |
| US6656696B2 (en) | 1999-02-26 | 2003-12-02 | Cyclacel | Compositions and methods for monitoring the phosphorylation of natural binding partners |
| US7166475B2 (en) | 1999-02-26 | 2007-01-23 | Cyclacel Ltd. | Compositions and methods for monitoring the modification state of a pair of polypeptides |
| US7060506B2 (en) * | 2000-01-31 | 2006-06-13 | Cyclacel, Ltd. | Compositions and methods for monitoring the modification of modification dependent binding partner polypeptides |
| SE0001530D0 (sv) * | 2000-04-27 | 2000-04-27 | Accuro Immunology Ab | A reporter protein |
| EP1290215A2 (de) * | 2000-06-07 | 2003-03-12 | Cyclacel Limited | Verfahren zur beobachtung von enzymaktivität |
| US6808874B2 (en) | 2000-06-13 | 2004-10-26 | Cyclacel Ltd. | Methods of monitoring enzyme activity |
| GB0214553D0 (en) * | 2002-06-25 | 2002-08-07 | Univ Leeds | Reporter module molecules having active ion channel activity |
| US7858386B2 (en) * | 2006-03-07 | 2010-12-28 | The United States Of America As Represented By The Secretary Of The Navy | Method of controlling quantum dot photoluminescence and other intrinsic properties through biological specificity |
| KR20120026838A (ko) * | 2010-09-10 | 2012-03-20 | 삼성전자주식회사 | 표적 서열 결합 단백질을 포함하는 키트 및 그를 이용한 표적 핵산의 검출 방법 |
| GB201306634D0 (en) | 2013-04-11 | 2013-05-29 | Univ Bristol | Cage-like particles |
| EP4698194A1 (de) * | 2023-04-19 | 2026-02-25 | St. Jude Children's Research Hospital, Inc. | Chimäre rezeptoren |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0537270T3 (da) * | 1990-07-02 | 1999-06-07 | Univ California | Påvisning af analytter ved overføring af fluorescensenergi |
| DE69309472T2 (de) * | 1992-01-23 | 1997-10-23 | Merck Patent Gmbh, 64293 Darmstadt | Fusionsproteine von monomeren und dimeren von antikörperfragmenten |
| US5824483A (en) * | 1994-05-18 | 1998-10-20 | Pence Inc. | Conformationally-restricted combinatiorial library composition and method |
| EP0854931A4 (de) * | 1995-10-06 | 2002-02-13 | Pence Inc | Methoden und zusammensetzungen für die detektion und reinigung von exprimierten proteinen über "coild coil heterodimer" wechselwirkungen |
| US6165335A (en) * | 1996-04-25 | 2000-12-26 | Pence And Mcgill University | Biosensor device and method |
| US6197928B1 (en) * | 1997-03-14 | 2001-03-06 | The Regents Of The University Of California | Fluorescent protein sensors for detection of analytes |
-
1997
- 1997-08-30 GB GBGB9718358.6A patent/GB9718358D0/en active Pending
-
1998
- 1998-09-01 CA CA002302394A patent/CA2302394A1/en not_active Abandoned
- 1998-09-01 GB GB0001228A patent/GB2342652B/en not_active Expired - Fee Related
- 1998-09-01 AU AU88727/98A patent/AU8872798A/en not_active Abandoned
- 1998-09-01 WO PCT/GB1998/002565 patent/WO1999011774A1/en not_active Ceased
- 1998-09-01 EP EP98940391A patent/EP1007653B1/de not_active Expired - Lifetime
- 1998-09-01 JP JP2000508785A patent/JP2001514849A/ja active Pending
- 1998-09-01 IL IL13417998A patent/IL134179A0/xx unknown
- 1998-09-01 DE DE69838333T patent/DE69838333T2/de not_active Expired - Fee Related
- 1998-09-01 AT AT98940391T patent/ATE371730T1/de not_active IP Right Cessation
-
2000
- 2000-02-24 NO NO20000901A patent/NO20000901L/no not_active Application Discontinuation
-
2002
- 2002-01-04 US US10/037,212 patent/US20030027220A1/en not_active Abandoned
- 2002-03-19 US US10/101,001 patent/US20030104504A1/en not_active Abandoned
-
2005
- 2005-08-10 US US11/200,995 patent/US20060148017A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| GB9718358D0 (en) | 1997-11-05 |
| DE69838333D1 (de) | 2007-10-11 |
| GB2342652A (en) | 2000-04-19 |
| GB0001228D0 (en) | 2000-03-08 |
| JP2001514849A (ja) | 2001-09-18 |
| AU8872798A (en) | 1999-03-22 |
| CA2302394A1 (en) | 1999-03-11 |
| US20030104504A1 (en) | 2003-06-05 |
| DE69838333T2 (de) | 2007-12-20 |
| EP1007653A1 (de) | 2000-06-14 |
| EP1007653B1 (de) | 2007-08-29 |
| US20060148017A1 (en) | 2006-07-06 |
| NO20000901D0 (no) | 2000-02-24 |
| NO20000901L (no) | 2000-04-28 |
| WO1999011774A1 (en) | 1999-03-11 |
| GB2342652B (en) | 2002-03-27 |
| US20030027220A1 (en) | 2003-02-06 |
| IL134179A0 (en) | 2001-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1007653 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |