ATE372342T1 - Substituierte aminoisoxazolinderivate und ihre verwendung als antidepressiva - Google Patents

Substituierte aminoisoxazolinderivate und ihre verwendung als antidepressiva

Info

Publication number: ATE372342T1
Authority: AT; Austria
Prior art keywords: aminoisoxazoline; antidepressants; derivatives; substituted; substituted aminoisoxazoline
Prior art date: 2002-04-02

Application number

AT03714897T

Other languages

English (en)

Inventor

Jose Andres-Gil

Manuel Alcazar-Vaca

Margaretha Henrica Mari Bakker

Lucas Olivares Ana De

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-02

Filing date

2003-03-27

Publication date

2007-09-15

2003-03-27 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2007-09-15 Application granted granted Critical

2007-09-15 Publication of ATE372342T1 publication Critical patent/ATE372342T1/de

Links

XPZOKPQZEPSMFC-UHFFFAOYSA-N 4,5-dihydro-1,2-oxazol-3-amine Chemical class NC1=NOCC1 XPZOKPQZEPSMFC-UHFFFAOYSA-N 0.000 title 1
239000000935 antidepressant agent Substances 0.000 title 1
229940005513 antidepressants Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Anesthesiology (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Addiction (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT03714897T 2002-04-02 2003-03-27 Substituierte aminoisoxazolinderivate und ihre verwendung als antidepressiva ATE372342T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02076239		2002-04-02

Publications (1)

Publication Number	Publication Date
ATE372342T1 true ATE372342T1 (de)	2007-09-15

Family

ID=28459528

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03714897T ATE372342T1 (de)	2002-04-02	2003-03-27	Substituierte aminoisoxazolinderivate und ihre verwendung als antidepressiva

Country Status (24)

Country	Link
US (1)	US7265103B2 (de)
EP (1)	EP1492796B1 (de)
JP (1)	JP4580653B2 (de)
KR (1)	KR20040093061A (de)
CN (1)	CN100349897C (de)
AR (1)	AR039207A1 (de)
AT (1)	ATE372342T1 (de)
BR (1)	BR0308309A (de)
CA (1)	CA2480113C (de)
DE (1)	DE60316134T2 (de)
DK (1)	DK1492796T3 (de)
EA (1)	EA008189B1 (de)
ES (1)	ES2292949T3 (de)
HK (1)	HK1080072A1 (de)
HR (1)	HRP20040871A2 (de)
IL (2)	IL164341A0 (de)
MX (1)	MXPA04008626A (de)
NO (1)	NO20044645L (de)
NZ (1)	NZ536109A (de)
PL (1)	PL211708B1 (de)
PT (1)	PT1492796E (de)
TW (1)	TWI286138B (de)
WO (1)	WO2003082878A1 (de)
ZA (1)	ZA200407904B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR040967A1 (es)	2002-08-12	2005-04-27	Janssen Pharmaceutica Nv	Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos
DE60319388T2 (de) *	2002-08-21	2009-02-19	Janssen Pharmaceutica N.V.	C6- und C9-substituierte Chromeno[4,3-c]Isoxazoline und ihre Verwendung als Anti-Depressiva
ES2331144T3 (es)	2004-11-26	2009-12-22	Janssen Pharmaceutica Nv	Derivados de isoxazolina-indol con actividad antipsicotica y ansiolitica mejorada.
BRPI0812833A2 (pt) *	2007-07-03	2014-12-09	Hoffmann La Roche	4-imidazolinas e seu uso como antidepressivos
KR20110128913A (ko)	2009-03-10	2011-11-30	다케다 야쿠힌 고교 가부시키가이샤	벤조푸란 유도체
US20130062732A1 (en)	2011-09-08	2013-03-14	International Business Machines Corporation	Interconnect structures with functional components and methods for fabrication
CN105801510A (zh) *	2016-04-08	2016-07-27	李勇	一种治疗抑郁症的药物组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0361577B1 (de)	1988-09-19	1993-05-05	Akzo N.V.	Tetrahydronaphthalin und Indan-Derivate
AU710059B2 (en) *	1996-01-05	1999-09-09	Aventis Pharmaceuticals Inc.	4,5-dihydronaphth(1,2-C)isoxazoles and derivatives thereof having CNS activity
US6187774B1 (en)	1996-03-04	2001-02-13	Yoshitomi Pharmaceutical Industries, Ltd.	Fused heterocyclic compounds and pharmaceutical applications thereof
HUP0303270A3 (en) *	2001-02-21	2007-03-28	Janssen Pharmaceutica Nv	Isoxazoline derivatives as anti-depressants, process for their preparation and pharmaceutical compositions containing them
AR040967A1 (es) *	2002-08-12	2005-04-27	Janssen Pharmaceutica Nv	Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos
DE60319388T2 (de) *	2002-08-21	2009-02-19	Janssen Pharmaceutica N.V.	C6- und C9-substituierte Chromeno[4,3-c]Isoxazoline und ihre Verwendung als Anti-Depressiva

2003
- 2003-03-27 ES ES03714897T patent/ES2292949T3/es not_active Expired - Lifetime
- 2003-03-27 WO PCT/EP2003/003245 patent/WO2003082878A1/en not_active Ceased
- 2003-03-27 NZ NZ536109A patent/NZ536109A/en unknown
- 2003-03-27 PL PL371630A patent/PL211708B1/pl unknown
- 2003-03-27 DE DE60316134T patent/DE60316134T2/de not_active Expired - Lifetime
- 2003-03-27 EP EP03714897A patent/EP1492796B1/de not_active Expired - Lifetime
- 2003-03-27 AT AT03714897T patent/ATE372342T1/de not_active IP Right Cessation
- 2003-03-27 HR HR20040871A patent/HRP20040871A2/hr not_active Application Discontinuation
- 2003-03-27 IL IL16434103A patent/IL164341A0/xx unknown
- 2003-03-27 HK HK05112213.1A patent/HK1080072A1/zh unknown
- 2003-03-27 BR BR0308309-8A patent/BR0308309A/pt not_active IP Right Cessation
- 2003-03-27 CA CA2480113A patent/CA2480113C/en not_active Expired - Fee Related
- 2003-03-27 JP JP2003580343A patent/JP4580653B2/ja not_active Expired - Fee Related
- 2003-03-27 US US10/510,220 patent/US7265103B2/en not_active Expired - Lifetime
- 2003-03-27 EA EA200401297A patent/EA008189B1/ru not_active IP Right Cessation
- 2003-03-27 KR KR10-2004-7012757A patent/KR20040093061A/ko not_active Ceased
- 2003-03-27 MX MXPA04008626A patent/MXPA04008626A/es active IP Right Grant
- 2003-03-27 PT PT03714897T patent/PT1492796E/pt unknown
- 2003-03-27 CN CNB038074192A patent/CN100349897C/zh not_active Expired - Fee Related
- 2003-03-27 DK DK03714897T patent/DK1492796T3/da active
- 2003-04-01 AR ARP030101126A patent/AR039207A1/es unknown
- 2003-04-01 TW TW092107328A patent/TWI286138B/zh not_active IP Right Cessation
2004
- 2004-09-28 IL IL164341A patent/IL164341A/en not_active IP Right Cessation
- 2004-09-30 ZA ZA200407904A patent/ZA200407904B/xx unknown
- 2004-10-27 NO NO20044645A patent/NO20044645L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP1492796B1 (de)	2007-09-05
AU2003219111A1 (en)	2003-10-13
MXPA04008626A (es)	2004-12-06
CA2480113C (en)	2012-04-24
TWI286138B (en)	2007-09-01
NZ536109A (en)	2006-06-30
PL211708B1 (pl)	2012-06-29
TW200406414A (en)	2004-05-01
EA008189B1 (ru)	2007-04-27
KR20040093061A (ko)	2004-11-04
NO20044645L (no)	2004-10-27
HRP20040871A2 (en)	2005-04-30
DE60316134T2 (de)	2008-05-29
US7265103B2 (en)	2007-09-04
IL164341A (en)	2009-06-15
AR039207A1 (es)	2005-02-09
PL371630A1 (en)	2005-06-27
BR0308309A (pt)	2004-12-28
CN1642960A (zh)	2005-07-20
HK1080072A1 (zh)	2006-04-21
JP2005522469A (ja)	2005-07-28
WO2003082878A1 (en)	2003-10-09
PT1492796E (pt)	2007-11-16
IL164341A0 (en)	2005-12-18
EA200401297A1 (ru)	2005-02-24
US20050222125A1 (en)	2005-10-06
EP1492796A1 (de)	2005-01-05
ES2292949T3 (es)	2008-03-16
CA2480113A1 (en)	2003-10-09
ZA200407904B (en)	2005-10-20
CN100349897C (zh)	2007-11-21
DE60316134D1 (de)	2007-10-18
DK1492796T3 (da)	2007-12-03
JP4580653B2 (ja)	2010-11-17

Legal Events

Date

Code

Title

Description

2008-02-15

UEP

Publication of translation of european patent specification

Ref document number: 1492796

Country of ref document: EP

2010-12-15

REN

Ceased due to non-payment of the annual fee

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