ATE427748T1 - Pyridin-derivate und ihre verwendung als urotensin ii antagonisten - Google Patents

Pyridin-derivate und ihre verwendung als urotensin ii antagonisten

Info

Publication number: ATE427748T1
Authority: AT; Austria
Prior art keywords: urotensin; antagonists; pyridine derivatives; pyridine; derivatives
Prior art date: 2003-09-26

Application number

AT04765436T

Other languages

English (en)

Inventor

Boris Mathys

Ller Claus M

Michael Scherz

Thomas Weller

Martine Clozel

Jirg Velker

Daniel Bur

Original Assignee

Actelion Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-09-26

Filing date

2004-09-21

Publication date

2009-04-15

2004-09-21 Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd

2009-04-15 Application granted granted Critical

2009-04-15 Publication of ATE427748T1 publication Critical patent/ATE427748T1/de

Links

JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical class C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1
239000005557 antagonist Substances 0.000 title 1
HFNHAPQMXICKCF-USJMABIRSA-N urotensin-ii Chemical compound N([C@@H](CC(O)=O)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=2C3=CC=CC=C3NC=2)NC(=O)[C@H](CC=2C=CC=CC=2)NC1=O)C(=O)N[C@@H](C(C)C)C(O)=O)C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O HFNHAPQMXICKCF-USJMABIRSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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AT04765436T 2003-09-26 2004-09-21 Pyridin-derivate und ihre verwendung als urotensin ii antagonisten ATE427748T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP0310746		2003-09-26

Publications (1)

Publication Number	Publication Date
ATE427748T1 true ATE427748T1 (de)	2009-04-15

Family

ID=34384524

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04765436T ATE427748T1 (de)	2003-09-26	2004-09-21	Pyridin-derivate und ihre verwendung als urotensin ii antagonisten

Country Status (18)

Country	Link
US (1)	US7750161B2 (de)
EP (1)	EP1670470B1 (de)
JP (1)	JP4851328B2 (de)
KR (1)	KR20070014108A (de)
CN (1)	CN1856305B (de)
AR (1)	AR045949A1 (de)
AT (1)	ATE427748T1 (de)
AU (1)	AU2004275488A1 (de)
BR (1)	BRPI0414777A (de)
CA (1)	CA2540196C (de)
DE (1)	DE602004020486D1 (de)
IL (1)	IL174497A0 (de)
MX (1)	MXPA06003264A (de)
NO (1)	NO20061395L (de)
RU (1)	RU2006113948A (de)
TW (1)	TW200526630A (de)
WO (1)	WO2005030209A1 (de)
ZA (1)	ZA200602442B (de)

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EP1631565A1 (de) *	2003-05-07	2006-03-08	Actelion Pharmaceuticals Ltd.	Piperazin-alkyl-harnstoff derivate

2004
- 2004-09-21 AU AU2004275488A patent/AU2004275488A1/en not_active Abandoned
- 2004-09-21 WO PCT/EP2004/010559 patent/WO2005030209A1/en not_active Ceased
- 2004-09-21 MX MXPA06003264A patent/MXPA06003264A/es unknown
- 2004-09-21 AT AT04765436T patent/ATE427748T1/de not_active IP Right Cessation
- 2004-09-21 BR BRPI0414777-4A patent/BRPI0414777A/pt not_active Application Discontinuation
- 2004-09-21 RU RU2006113948/04A patent/RU2006113948A/ru unknown
- 2004-09-21 KR KR1020067005848A patent/KR20070014108A/ko not_active Withdrawn
- 2004-09-21 JP JP2006527332A patent/JP4851328B2/ja not_active Expired - Fee Related
- 2004-09-21 CN CN2004800277254A patent/CN1856305B/zh not_active Expired - Fee Related
- 2004-09-21 EP EP04765436A patent/EP1670470B1/de not_active Expired - Lifetime
- 2004-09-21 CA CA2540196A patent/CA2540196C/en not_active Expired - Fee Related
- 2004-09-21 DE DE602004020486T patent/DE602004020486D1/de not_active Expired - Lifetime
- 2004-09-21 US US10/573,516 patent/US7750161B2/en not_active Expired - Fee Related
- 2004-09-24 AR ARP040103475A patent/AR045949A1/es unknown
- 2004-09-24 TW TW093129149A patent/TW200526630A/zh unknown
2006
- 2006-03-22 IL IL174497A patent/IL174497A0/en unknown
- 2006-03-24 ZA ZA200602442A patent/ZA200602442B/en unknown
- 2006-03-27 NO NO20061395A patent/NO20061395L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO20061395L (no)	2006-06-22
JP4851328B2 (ja)	2012-01-11
RU2006113948A (ru)	2007-11-10
CN1856305B (zh)	2010-04-28
DE602004020486D1 (de)	2009-05-20
CA2540196C (en)	2012-03-20
MXPA06003264A (es)	2006-06-08
AU2004275488A1 (en)	2005-04-07
WO2005030209A1 (en)	2005-04-07
CA2540196A1 (en)	2005-04-07
CN1856305A (zh)	2006-11-01
WO2005030209A8 (en)	2006-05-11
US20070043081A1 (en)	2007-02-22
AR045949A1 (es)	2005-11-16
US7750161B2 (en)	2010-07-06
BRPI0414777A (pt)	2006-11-21
EP1670470A1 (de)	2006-06-21
JP2007506692A (ja)	2007-03-22
TW200526630A (en)	2005-08-16
ZA200602442B (en)	2007-09-26
EP1670470B1 (de)	2009-04-08
IL174497A0 (en)	2006-08-01
KR20070014108A (ko)	2007-01-31

Legal Events

Date	Code	Title	Description
2009-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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