ATE374038T1 - Verwendung von bakteriellen pard kis/pard kid toxin-antitoxin system zur tötung von eukaryotischen zellen - Google Patents

Verwendung von bakteriellen pard kis/pard kid toxin-antitoxin system zur tötung von eukaryotischen zellen

Info

Publication number
ATE374038T1
ATE374038T1 AT00946124T AT00946124T ATE374038T1 AT E374038 T1 ATE374038 T1 AT E374038T1 AT 00946124 T AT00946124 T AT 00946124T AT 00946124 T AT00946124 T AT 00946124T AT E374038 T1 ATE374038 T1 AT E374038T1
Authority
AT
Austria
Prior art keywords
pard
bacterial
kis
eukaryotic cells
toxin
Prior art date
Application number
AT00946124T
Other languages
English (en)
Inventor
La Cueva Mendez Guillermo De
Ronald Alfred Laskey
Anthony David Mills
Orejas Ramon Diaz
Original Assignee
Cancer Res Ventures Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Res Ventures Ltd filed Critical Cancer Res Ventures Ltd
Application granted granted Critical
Publication of ATE374038T1 publication Critical patent/ATE374038T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
AT00946124T 1999-07-16 2000-07-17 Verwendung von bakteriellen pard kis/pard kid toxin-antitoxin system zur tötung von eukaryotischen zellen ATE374038T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9916810.6A GB9916810D0 (en) 1999-07-16 1999-07-16 Killing cells

Publications (1)

Publication Number Publication Date
ATE374038T1 true ATE374038T1 (de) 2007-10-15

Family

ID=10857441

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00946124T ATE374038T1 (de) 1999-07-16 2000-07-17 Verwendung von bakteriellen pard kis/pard kid toxin-antitoxin system zur tötung von eukaryotischen zellen

Country Status (8)

Country Link
EP (1) EP1198239B1 (de)
AT (1) ATE374038T1 (de)
AU (1) AU6000700A (de)
CA (1) CA2379325A1 (de)
DE (1) DE60036551T2 (de)
ES (1) ES2295037T3 (de)
GB (1) GB9916810D0 (de)
WO (1) WO2001005421A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7491699B2 (en) 2002-12-09 2009-02-17 Ramot At Tel Aviv University Ltd. Peptide nanostructures and methods of generating and using the same
EP1663199B1 (de) 2003-09-25 2013-04-03 Tel Aviv University Future Technology Development L.P. Zusammensetzungen und diese verwendende verfahren zur behandlung von amyloid-bedingten erkrankungen
WO2005031362A2 (en) * 2003-10-02 2005-04-07 Ramot At Tel Aviv University Ltd. Novel antibacterial agents and methods of identifying and utilizing same
WO2005074986A2 (en) * 2004-02-10 2005-08-18 Genobiotix Aps Bioactive species capable of interfering with a microbial toxin-antitoxin complex and methods for evaluation and use of said bioactive species
EP1781310B1 (de) 2004-08-02 2015-10-14 Ramot at Tel Aviv University Ltd. Artikel von peptidnanostrukturen und herstellungsverfahren dafür
US7732479B2 (en) 2004-08-19 2010-06-08 Tel Aviv University Future Technology Development L.P. Compositions for treating amyloid associated diseases
EP1973928A2 (de) 2005-10-11 2008-10-01 Ramot at Tel-Aviv University Ltd. Selbstzusammengebaute fmoc-ff-hydrogele
CN101903524A (zh) * 2007-08-31 2010-12-01 巴斯夫植物科学有限公司 病原体控制基因及其在植物中的使用方法
EP2570134A1 (de) * 2011-09-15 2013-03-20 De la Cueva-Mendez, Guillermo Systeme und Verfahren zum Verringern des Zellwachstums und Einbinden der selektiven Abtötung von Zielzellen
US20140359795A1 (en) * 2013-05-31 2014-12-04 Recombinetics, Inc. Genetic techniques for making animals with sortable sperm
WO2019047166A1 (en) * 2017-09-08 2019-03-14 New Portal Limited NUCLEIC ACID SYSTEMS THAT ALLOW BACTERIA TO SPECIFICALLY TARGET SOLID TUMORS THROUGH GLUCOSE DEPENDENT VIABILITY
WO2022006748A1 (en) 2020-07-07 2022-01-13 New Portal Limited Genetically engineered live bacteria and methods of constructing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE286405T1 (de) * 1993-05-14 2005-01-15 Stephen S Arnon Verfahren zur verhütung der nebenwirkungen und unempfindlichkeit gegenüber therapeutischen verwendungen von toxinen
CA2327387C (en) * 1998-05-07 2012-07-03 Gx Biosystems A/S Cytotoxin-based biological containment

Also Published As

Publication number Publication date
EP1198239B1 (de) 2007-09-26
DE60036551D1 (de) 2007-11-08
WO2001005421A1 (en) 2001-01-25
ES2295037T3 (es) 2008-04-16
CA2379325A1 (en) 2001-01-25
DE60036551T2 (de) 2008-06-26
GB9916810D0 (en) 1999-09-22
AU6000700A (en) 2001-02-05
EP1198239A1 (de) 2002-04-24

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Legal Events

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