ATE374525T1 - Transgenes fibrinogen - Google Patents

Transgenes fibrinogen

Info

Publication number: ATE374525T1
Authority: AT; Austria
Prior art keywords: fibrinogens; animals; modified; human; subunit
Prior art date: 1994-02-18

Application number

AT95911012T

Other languages

English (en)

Inventor

William Velander

Susan Lord

William Drohan

Henryk Lubon

John Johnson

Christopher Russell

Original Assignee

American Nat Red Cross

Virginia Tech Intell Prop

Univ North Carolina

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-02-18

Filing date

1995-02-17

Publication date

2007-10-15

1995-02-17 Application filed by American Nat Red Cross, Virginia Tech Intell Prop, Univ North Carolina filed Critical American Nat Red Cross

2007-10-15 Application granted granted Critical

2007-10-15 Publication of ATE374525T1 publication Critical patent/ATE374525T1/de

Links

FBPFZTCFMRRESA-ZXXMMSQZSA-N D-iditol Chemical compound OC[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-ZXXMMSQZSA-N 0.000 title abstract 5
102000008946 Fibrinogen Human genes 0.000 title abstract 4
108010049003 Fibrinogen Proteins 0.000 title abstract 4
230000009261 transgenic effect Effects 0.000 title abstract 2
229940012952 fibrinogen Drugs 0.000 title 1
241001465754 Metazoa Species 0.000 abstract 2
229920001184 polypeptide Polymers 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
210000001124 body fluid Anatomy 0.000 abstract 1
239000010839 body fluid Substances 0.000 abstract 1
102000037865 fusion proteins Human genes 0.000 abstract 1
108020001507 fusion proteins Proteins 0.000 abstract 1
210000005075 mammary gland Anatomy 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
230000003248 secreting effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Environmental Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Hematology (AREA)
Animal Behavior & Ethology (AREA)
Microbiology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physics & Mathematics (AREA)
Animal Husbandry (AREA)
Biodiversity & Conservation Biology (AREA)
Plant Pathology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Materials For Medical Uses (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT95911012T 1994-02-18 1995-02-17 Transgenes fibrinogen ATE374525T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US19806894A	1994-02-18	1994-02-18

Publications (1)

Publication Number	Publication Date
ATE374525T1 true ATE374525T1 (de)	2007-10-15

Family

ID=22731871

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95911012T ATE374525T1 (de)	1994-02-18	1995-02-17	Transgenes fibrinogen

Country Status (9)

Country	Link
EP (1)	EP0744891B1 (de)
JP (1)	JPH10500003A (de)
AT (1)	ATE374525T1 (de)
CA (1)	CA2183546C (de)
DE (1)	DE69535604T2 (de)
DK (1)	DK0744891T3 (de)
ES (1)	ES2296289T3 (de)
PT (1)	PT744891E (de)
WO (1)	WO1995022249A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6660842B1 (en)	1994-04-28	2003-12-09	Tripep Ab	Ligand/receptor specificity exchangers that redirect antibodies to receptors on a pathogen
US6933366B2 (en)	1996-12-27	2005-08-23	Tripep Ab	Specificity exchangers that redirect antibodies to bacterial adhesion receptors
US6344596B1 (en) *	1997-02-14	2002-02-05	American Red Cross	Expression of active human factor IX in mammary tissue and of milk non human transgenic mammals
US20020184655A1 (en) *	1997-12-01	2002-12-05	Henryk Lubon	Methods for the degradation and detoxification of organic material using urine produced by transgenic animals and related transgenic animals and proteins
JP2002525047A (ja) *	1998-09-16	2002-08-13	ネクシアバイオテクノロジーズ，インコーポレイテッド	尿における組換え蛋白質の産生
DK1115745T3 (da) *	1998-09-24	2006-10-02	Pharming Intellectual Pty Bv	Oprensning af fibrinogen fra væsker ved udfældning og hydrofob interaktionskromatografi
US7030289B2 (en)	1998-11-19	2006-04-18	Ppl Therapeutics (Scotland) Ltd	Stabilization of milk from transgenic animals
GB9825374D0 (en) *	1998-11-19	1999-01-13	Ppl Therapeutics Scotland Ltd	Method
NZ511299A (en) *	1998-11-19	2003-02-28	Ppl Therapeutics Scotland Ltd	Stabilisation of milk from transgenic animals through expression of a serine proteinase inhibitor and optionally fibrinogen in the mammary gland
KR20030034194A (ko) *	2000-09-19	2003-05-01	트리펩 아베	병원체 내에서 수용체에 대한 항체를 재유도하는리간드/수용체 특이성 교환기
US7335359B2 (en)	2003-02-06	2008-02-26	Tripep Ab	Glycosylated specificity exchangers
EP2230249A3 (de)	2003-02-06	2010-12-22	ChronTech Pharma AB	Antigen/Antikörper oder Ligand/Rezeptor glycosylierter Spezifität Austauscher
WO2005010178A1 (ja) *	2003-07-29	2005-02-03	Juridical Foundation The Chemo-Sero-Therapeutic Research Institute	組換えフィブリノゲン高産生細胞の作製方法及び高産生細胞
US8557773B2 (en)	2008-05-02	2013-10-15	Laboratoire Francais Du Fractionnement Et Des Biotechnologies	Treatment of bleeding with low half-life fibrinogen
WO2010129258A2 (en)	2009-04-27	2010-11-11	Mallinckrodt Inc.	Tissue sealant compositions, vascular closure devices, and uses thereof
EP2547337A1 (de)	2010-03-17	2013-01-23	Pharming Intellectual Property B.V.	Verwendung von antikoagulanzien bei der herstellung von rekombinanten proteinen in der milch von transgenen tieren
JP5839810B2 (ja) *	2011-03-03	2016-01-06	日本製粉株式会社	フィブリノゲンを産生するトランスジェニックカイコ
EP2556842A1 (de)	2011-08-11	2013-02-13	Bioftalmik, S.L.	Zusammensetzung in Form einer Folie mit Fibrinogen und Fibrinogenaktivator sowie Anwendungen dafür

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0591219B1 (de) *	1991-01-11	2001-12-19	American Red Cross	Expression von aktivem menschlichem Protein C im Milchdrüsengewebe transgener Tiere

1995
- 1995-02-17 AT AT95911012T patent/ATE374525T1/de active
- 1995-02-17 DE DE69535604T patent/DE69535604T2/de not_active Expired - Lifetime
- 1995-02-17 JP JP7521903A patent/JPH10500003A/ja active Pending
- 1995-02-17 EP EP95911012A patent/EP0744891B1/de not_active Expired - Lifetime
- 1995-02-17 PT PT95911012T patent/PT744891E/pt unknown
- 1995-02-17 WO PCT/US1995/001944 patent/WO1995022249A1/en not_active Ceased
- 1995-02-17 ES ES95911012T patent/ES2296289T3/es not_active Expired - Lifetime
- 1995-02-17 CA CA002183546A patent/CA2183546C/en not_active Expired - Lifetime
- 1995-02-17 DK DK95911012T patent/DK0744891T3/da active

Also Published As

Publication number	Publication date
ES2296289T3 (es)	2008-04-16
DE69535604T2 (de)	2008-05-21
CA2183546C (en)	2001-08-21
DK0744891T3 (da)	2008-02-04
EP0744891A1 (de)	1996-12-04
JPH10500003A (ja)	1998-01-06
WO1995022249A1 (en)	1995-08-24
PT744891E (pt)	2008-01-14
CA2183546A1 (en)	1995-08-24
EP0744891B1 (de)	2007-10-03
DE69535604D1 (en)	2007-11-15

Legal Events

Date

Code

Title

Description

2008-03-15

UEP

Publication of translation of european patent specification

Ref document number: 0744891

Country of ref document: EP

Publication	Publication Date	Title
ATE374525T1 (de)	2007-10-15	Transgenes fibrinogen
EP0737746A3 (de)	1996-10-23	Herstellung rekombinanter Polypeptide durch Rinderarte und Transgenmethoden
DE69534295D1 (de)	2005-08-04	Fibrinogenproduktion in transgenen tieren
ATE391181T1 (de)	2008-04-15	Bioaktive il-12 fusionsproteine
ATE184647T1 (de)	1999-10-15	Embryonische stammzelle zur herstellung von chimäre und transgen-ongulaten
NZ521396A (en)	2004-06-25	Fusion proteins comprising two or more Neisseria polypeptides
DK1218504T3 (da)	2007-11-12	GL50 molekyler og anvendelser deraf
DE3382837D1 (de)	2003-03-13	Herstellung von funktionellen, menschlichen Urokinaseproteinen
BR9206578A (pt)	1995-04-11	Seqüência de DNA sintético tendo melhorada atividade inseticida em milho.
DE3752130D1 (de)	1997-11-20	Herstellung von peptiden
WO1996034966A3 (en)	1996-12-05	Engineering protein posttranslational modification in transgenic organisms
ATE273388T1 (de)	2004-08-15	Veränderte menschliche c3-proteine
DK175989A (da)	1989-10-20	Fremgangsmaade til fremstilling af protein
WO2001019846A8 (en)	2001-04-19	Transgenically produced fusion proteins
ATE139541T1 (de)	1996-07-15	Kollagen-bindendes protein sowie dessen herstellung
ATE294861T1 (de)	2005-05-15	Polypeptide mit opioider rezeptor-aktvität, für sie kodierende nukleinsäuren und ihre verwendungen
EP1147184A4 (de)	2002-10-21	Kontrollierte expression von heterologen proteinen in der milchdrüse eines transgenen tieres
ATE36348T1 (de)	1988-08-15	Herstellungsverfahren und selektive isolierung von proteinen und polypeptiden, rekombinant und expressionsvektor dazu und schmelzprotein das zum konstanten teil von immoglobulinen binden kann.