ATE375350T1 - Modulatoren von peroxisome proliferator- aktivierten rezeptoren - Google Patents
Modulatoren von peroxisome proliferator- aktivierten rezeptorenInfo
- Publication number
- ATE375350T1 ATE375350T1 AT03706045T AT03706045T ATE375350T1 AT E375350 T1 ATE375350 T1 AT E375350T1 AT 03706045 T AT03706045 T AT 03706045T AT 03706045 T AT03706045 T AT 03706045T AT E375350 T1 ATE375350 T1 AT E375350T1
- Authority
- AT
- Austria
- Prior art keywords
- modulators
- peroxisome proliferator
- activated receptors
- aliphatic linker
- acylsulfonamide
- Prior art date
Links
- 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 title 1
- 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 title 1
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229940124530 sulfonamide Drugs 0.000 abstract 2
- 150000003456 sulfonamides Chemical class 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 150000003536 tetrazoles Chemical class 0.000 abstract 2
- -1 acylsulfonamide Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- SOWBFZRMHSNYGE-UHFFFAOYSA-N oxamic acid Chemical compound NC(=O)C(O)=O SOWBFZRMHSNYGE-UHFFFAOYSA-N 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35942802P | 2002-02-21 | 2002-02-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE375350T1 true ATE375350T1 (de) | 2007-10-15 |
Family
ID=27766083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03706045T ATE375350T1 (de) | 2002-02-21 | 2003-02-07 | Modulatoren von peroxisome proliferator- aktivierten rezeptoren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050250831A1 (de) |
| EP (1) | EP1490058B1 (de) |
| JP (1) | JP2005523292A (de) |
| AT (1) | ATE375350T1 (de) |
| AU (1) | AU2003207808A1 (de) |
| DE (1) | DE60316780T2 (de) |
| ES (1) | ES2292937T3 (de) |
| WO (1) | WO2003072099A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2297382T3 (es) | 2003-02-14 | 2008-05-01 | Eli Lilly And Company | Derivados de sulfonamida como moduladores de ppar. |
| US7262318B2 (en) * | 2004-03-10 | 2007-08-28 | Pfizer, Inc. | Substituted heteroaryl- and phenylsulfamoyl compounds |
| US20050288340A1 (en) * | 2004-06-29 | 2005-12-29 | Pfizer Inc | Substituted heteroaryl- and phenylsulfamoyl compounds |
| US8187727B2 (en) | 2005-07-22 | 2012-05-29 | Lg Chem, Ltd. | Imidazole derivatives, preparation method thereof and organic electronic device using the same |
| JP5294419B2 (ja) * | 2007-04-05 | 2013-09-18 | 第一三共株式会社 | 縮合二環式ヘテロアリール誘導体 |
| CA2754446A1 (en) | 2009-03-05 | 2010-09-10 | Daiichi Sankyo Company, Limited | Pyridine derivative |
| GB201617630D0 (en) | 2016-10-18 | 2016-11-30 | Cellcentric Ltd | Pharmaceutical compounds |
| GB201806320D0 (en) | 2018-04-18 | 2018-05-30 | Cellcentric Ltd | Process |
| BR112022010924A2 (pt) | 2019-12-06 | 2022-09-06 | Vertex Pharma | Tetra-hidrofuranos substituídos como moduladores de canais de sódio |
| CN114901641B (zh) * | 2020-02-28 | 2025-06-17 | 四川科伦博泰生物医药股份有限公司 | 芳香族化合物及其药物组合物和用途 |
| SMT202500481T1 (it) | 2021-06-04 | 2026-01-12 | Vertex Pharma | N-(idrossialchil(etero)aril)tetraidrofuran carbossammidi come modulatori di canali del sodio |
| CN118159338A (zh) | 2021-08-10 | 2024-06-07 | 奇特实验室有限责任公司 | 用于毛发治疗的组合物、制剂和方法 |
| US12251459B2 (en) | 2022-10-12 | 2025-03-18 | Oddity Labs, Llc | Compositions, formulations, and methods for hair treatment |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2641060A1 (de) * | 1976-09-11 | 1978-03-16 | Hoechst Ag | Beta-lactamverbindungen und verfahren zu ihrer herstellung |
| DE2907089A1 (de) * | 1979-02-23 | 1980-09-04 | Hoechst Ag | Herbizide mittel |
| NZ193011A (en) * | 1979-03-19 | 1983-03-15 | Ici Australia Ltd | Diarylamine derivatives intermediates herbicidal compositions |
| EP0157225B1 (de) * | 1984-03-14 | 1988-01-20 | CASSELLA Aktiengesellschaft | Verfahren zur Herstellung von Benzimidazolyl,-Benzoxazolyl- und Benzthiazolyloxyphenoxypropionsäurederivaten |
| FR2766822B1 (fr) * | 1997-07-30 | 2001-02-23 | Adir | Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| RU2219172C2 (ru) * | 1999-04-06 | 2003-12-20 | Санкио Компани, Лимитед | α-ЗАМЕЩЕННЫЕ ПРОИЗВОДНЫЕ КАРБОНОВЫХ КИСЛОТ |
| YU72201A (sh) * | 1999-04-28 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | Derivati di-aril kiseline kao ppar receptorski ligandi |
| FR2829765A1 (fr) * | 2001-09-14 | 2003-03-21 | Lipha | Derives imidazolylalkoxylarylalcanoiques leurs applications en therapeutique |
-
2003
- 2003-02-07 DE DE60316780T patent/DE60316780T2/de not_active Expired - Fee Related
- 2003-02-07 AT AT03706045T patent/ATE375350T1/de not_active IP Right Cessation
- 2003-02-07 WO PCT/US2003/003112 patent/WO2003072099A1/en not_active Ceased
- 2003-02-07 US US10/502,696 patent/US20050250831A1/en not_active Abandoned
- 2003-02-07 ES ES03706045T patent/ES2292937T3/es not_active Expired - Lifetime
- 2003-02-07 AU AU2003207808A patent/AU2003207808A1/en not_active Abandoned
- 2003-02-07 JP JP2003570845A patent/JP2005523292A/ja active Pending
- 2003-02-07 EP EP03706045A patent/EP1490058B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20050250831A1 (en) | 2005-11-10 |
| DE60316780D1 (de) | 2007-11-22 |
| JP2005523292A (ja) | 2005-08-04 |
| AU2003207808A1 (en) | 2003-09-09 |
| WO2003072099A1 (en) | 2003-09-04 |
| DE60316780T2 (de) | 2008-07-24 |
| EP1490058B1 (de) | 2007-10-10 |
| ES2292937T3 (es) | 2008-03-16 |
| EP1490058A1 (de) | 2004-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |