ATE376837T1 - Stimulierung oder hemmung von angiogenese und herzvaskularisierung mit tumor nekrose faktor ligand/rezeptor homologen - Google Patents

Stimulierung oder hemmung von angiogenese und herzvaskularisierung mit tumor nekrose faktor ligand/rezeptor homologen

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Publication number
ATE376837T1
ATE376837T1 AT00947204T AT00947204T ATE376837T1 AT E376837 T1 ATE376837 T1 AT E376837T1 AT 00947204 T AT00947204 T AT 00947204T AT 00947204 T AT00947204 T AT 00947204T AT E376837 T1 ATE376837 T1 AT E376837T1
Authority
AT
Austria
Prior art keywords
angiogenesis
stimulation
inhibition
necrosis factor
tumor necrosis
Prior art date
Application number
AT00947204T
Other languages
English (en)
Inventor
P Williams
Mary Gerritsen
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE376837T1 publication Critical patent/ATE376837T1/de

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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • G—PHYSICS
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    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/525—Tumor necrosis factor [TNF]
    • G—PHYSICS
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    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153 or CD154
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    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95

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  • Hematology (AREA)
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  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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AT00947204T 1999-07-12 2000-07-11 Stimulierung oder hemmung von angiogenese und herzvaskularisierung mit tumor nekrose faktor ligand/rezeptor homologen ATE376837T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14330499P 1999-07-12 1999-07-12

Publications (1)

Publication Number Publication Date
ATE376837T1 true ATE376837T1 (de) 2007-11-15

Family

ID=22503468

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Application Number Title Priority Date Filing Date
AT00947204T ATE376837T1 (de) 1999-07-12 2000-07-11 Stimulierung oder hemmung von angiogenese und herzvaskularisierung mit tumor nekrose faktor ligand/rezeptor homologen

Country Status (12)

Country Link
US (1) US20050202008A1 (de)
EP (1) EP1196186B1 (de)
JP (1) JP2003504343A (de)
AT (1) ATE376837T1 (de)
AU (3) AU6085700A (de)
CA (1) CA2378179A1 (de)
DE (1) DE60036945T2 (de)
DK (1) DK1196186T3 (de)
ES (1) ES2295040T3 (de)
IL (2) IL147442A0 (de)
PT (1) PT1196186E (de)
WO (1) WO2001003720A2 (de)

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WO2001003720A2 (en) 2001-01-18
DE60036945T2 (de) 2008-08-21
AU2009200385A1 (en) 2009-02-26
AU2005203642A1 (en) 2005-09-08
DK1196186T3 (da) 2008-03-03
PT1196186E (pt) 2008-02-14
EP1196186A2 (de) 2002-04-17
IL147442A (en) 2010-11-30
ES2295040T3 (es) 2008-04-16
DE60036945D1 (de) 2007-12-13
AU6085700A (en) 2001-01-30
US20050202008A1 (en) 2005-09-15
WO2001003720A9 (en) 2001-07-05
WO2001003720A3 (en) 2001-06-14
IL147442A0 (en) 2002-08-14
EP1196186B1 (de) 2007-10-31
CA2378179A1 (en) 2001-01-18
JP2003504343A (ja) 2003-02-04

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