ATE377755T1 - Kryptate der seltenen erden mit verringerter fluoreszenz-löschung - Google Patents

Kryptate der seltenen erden mit verringerter fluoreszenz-löschung

Info

Publication number
ATE377755T1
ATE377755T1 AT01951580T AT01951580T ATE377755T1 AT E377755 T1 ATE377755 T1 AT E377755T1 AT 01951580 T AT01951580 T AT 01951580T AT 01951580 T AT01951580 T AT 01951580T AT E377755 T1 ATE377755 T1 AT E377755T1
Authority
AT
Austria
Prior art keywords
rare earth
quention
reduced fluorescence
earth cryptates
cryptates
Prior art date
Application number
AT01951580T
Other languages
English (en)
Inventor
Herve Autiero
Herve Bazin
Gerard Mathis
Original Assignee
Cis Bio Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cis Bio Int filed Critical Cis Bio Int
Application granted granted Critical
Publication of ATE377755T1 publication Critical patent/ATE377755T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/40—Rare earth chelates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Pyridine Compounds (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Luminescent Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT01951580T 2000-06-15 2001-06-12 Kryptate der seltenen erden mit verringerter fluoreszenz-löschung ATE377755T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0007650A FR2810406B1 (fr) 2000-06-15 2000-06-15 Nouveaux cryptates de terre rare peu sensibles a l'extinction de fluorescence

Publications (1)

Publication Number Publication Date
ATE377755T1 true ATE377755T1 (de) 2007-11-15

Family

ID=8851298

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01951580T ATE377755T1 (de) 2000-06-15 2001-06-12 Kryptate der seltenen erden mit verringerter fluoreszenz-löschung

Country Status (8)

Country Link
US (1) US7087384B2 (de)
EP (1) EP1290448B1 (de)
JP (1) JP2004509075A (de)
AT (1) ATE377755T1 (de)
AU (1) AU7246801A (de)
DE (1) DE60131276T2 (de)
FR (1) FR2810406B1 (de)
WO (1) WO2001096877A2 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005020384A1 (de) * 2005-05-02 2006-11-09 Therainvention Gmbh Spektroskopisches Verfahren zum Nachweis von Analyten
FR2890174B1 (fr) 2005-08-30 2009-04-24 Cis Bio Internat Sa Procede pour la mise en evidence d'un processus biologique par mesure d'un fret
FR2890446B1 (fr) 2005-09-05 2008-04-18 Cis Bio Internat Sa Methode de detection d'interaction intracellulaire entre bio-molecules
JP2011523052A (ja) 2008-05-23 2011-08-04 アミリン・ファーマシューティカルズ，インコーポレイテッド Ｇｌｐ−１受容体アゴニスト・バイオアッセイ
FR2934684B1 (fr) 2008-07-31 2012-11-16 Cis Bio Int Methode de detection de l'internalisation de proteines membranaires.
FR2936245B1 (fr) 2008-09-23 2012-07-06 Cis Bio Int Nouveaux substrats d'o6-alkylguanine-adn alkyltransferase et ses mutants.
FR2940286B1 (fr) 2008-12-19 2011-04-08 Cis Bio Int Nouveaux cryptates de terres rares comportant un motif tetraazatriphenylene
WO2010125314A1 (fr) 2009-04-30 2010-11-04 Cis-Bio International Procede de detection de composes modulateurs de dimeres de proteines membranaires a domaine vft
FR2949156B1 (fr) 2009-08-13 2016-04-15 Cis-Bio Int Methode de determination de la liaison d'un compose donne a un recepteur membranaire
US8623324B2 (en) 2010-07-21 2014-01-07 Aat Bioquest Inc. Luminescent dyes with a water-soluble intramolecular bridge and their biological conjugates
FR2977674B1 (fr) 2011-07-06 2015-08-14 Cisbio Bioassays Methode amelioree de detection et/ou de quantification d'un analyte present a la surface d'une cellule
FR2978149B1 (fr) 2011-07-18 2014-01-10 Cisbio Bioassays Nouveaux agents complexants et complexes de lanthanide correspondant, et leur utilisation comme marqueurs luminescents
FR2980271B1 (fr) 2011-09-16 2013-10-11 Cisbio Bioassays Procede de determination de la glycosylation d'un anticorps
WO2013124544A1 (fr) 2012-02-22 2013-08-29 Cisbio Bioassays Procede de normalisation de la luminescence emise par un milieu de mesure.
FR2988174B1 (fr) 2012-03-19 2014-04-25 Cisbio Bioassays Procede de determination de la capacite d'un anticorps a maintenir des cellules a proximite l'une de l'autre
FR3000960B1 (fr) 2013-01-16 2015-03-06 Cisbio Bioassays Nouveaux agents complexants hydrosolubles et complexes de lanthanide correspondants
FR3004189B1 (fr) 2013-04-04 2015-09-04 Ecole Norm Superieure Lyon Complexes de lanthanide comprenant au moins deux groupes betaines, utiles comme marqueurs luminescents
FR3032797B1 (fr) 2015-02-13 2017-03-03 Cisbio Bioassays Procede de quantification d'une proteine d'interet presente dans un echantillon biologique
FR3045053B1 (fr) 2015-12-09 2018-01-05 Cisbio Bioassays Agents complexants hydrosolubles a base de triazapyridinophane et complexes de lanthanide fluorescents correspondants
WO2017105928A1 (en) 2015-12-16 2017-06-22 Becton, Dickinson And Company Photostable fluorescent polymeric tandem dyes including luminescent metal complexes
CN106432298A (zh) * 2016-09-05 2017-02-22 中国科学院苏州生物医学工程技术研究所 一种镧系金属穴醚配合物及其制备方法与用途
FR3067349B1 (fr) 2017-06-12 2020-12-04 Cisbio Bioassays Nouveaux agents mono et di-antennes complexants hydrosolubles et complexes de lanthanide correspondants
FR3067712B1 (fr) 2017-06-14 2019-08-02 Cisbio Bioassays Nouveaux agents complexants de type trimethoxyphenyl pyridine hydrosolubles et complexes de lanthanide correspondants
FR3069644B1 (fr) 2017-07-28 2024-07-12 Cisbio Bioassays Methode pour mesurer la modulation de l'activation d'un recepteur couple a une proteine g
FR3084365B1 (fr) 2018-07-27 2020-10-23 Cisbio Bioassays Anticorps a domaine unique qui se lient a la proteine g alpha
CN109180571B (zh) * 2018-10-26 2021-08-13 章健 一种联吡啶衍生物及合成方法、用途
FR3092115B1 (fr) 2019-01-30 2021-11-12 Cisbio Bioassays analogues de GTP fluorescents et utilisation
FR3092172B1 (fr) 2019-01-30 2021-02-12 Cisbio Bioassays Méthode pour mesurer la modulation de l’activation d’un récepteur couplé à une protéine G avec des analogues du GTP
CN112341462A (zh) * 2020-11-04 2021-02-09 济南国科医工科技发展有限公司 稀土镝穴醚荧光配合物及其制备方法
CN114324862B (zh) * 2021-12-31 2025-03-07 成都微瑞生物科技有限公司 一种非洲猪瘟病毒均相检测反应试剂及检测方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2570703B1 (fr) * 1984-09-26 1988-07-08 Commissariat Energie Atomique Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents
FR2624862B1 (fr) * 1987-12-18 1990-06-08 Oris Ind Cryptates de terres rares, procedes d'obtention, intermediaires de synthese et application a titre de marqueurs fluorescents
US5696240A (en) * 1991-03-15 1997-12-09 Vallarino; Lidia M. Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities
EP0778844B1 (de) * 1994-09-02 2002-12-18 Novartis AG Funktionelle terpyridin-metallkomplexe, verfahren zu deren herstellung und oligonukleotid-konjugate mit terpyridin-metallkomplexen
FR2769315B1 (fr) * 1997-10-03 2001-06-08 Cis Bio Int Conjugues fluorescents de nucleosides ou de nucleotides, leur procede de preparation et leur utilisation

Also Published As

Publication number Publication date
US7087384B2 (en) 2006-08-08
WO2001096877A3 (en) 2002-04-11
EP1290448B1 (de) 2007-11-07
DE60131276D1 (de) 2007-12-20
JP2004509075A (ja) 2004-03-25
DE60131276T2 (de) 2008-08-28
US20040092726A1 (en) 2004-05-13
FR2810406A1 (fr) 2001-12-21
AU7246801A (en) 2001-12-24
EP1290448A2 (de) 2003-03-12
FR2810406B1 (fr) 2002-09-20
WO2001096877A2 (en) 2001-12-20

Similar Documents

Publication Publication Date Title
ATE377755T1 (de) Kryptate der seltenen erden mit verringerter fluoreszenz-löschung
ATE409238T1 (de) Nachweis der hybridisierung von nukleinsäuren durch fluoreszenzpolarisation
DK1230375T3 (da) Inhibering af genekspression med dsRNA
TR200003036T2 (tr) 12,13-Modifiye edilmiş epotilon türevleri
DE69900813D1 (de) Asymmetrische cyaninfarbstoffe als fluoreszenzlöscher
ATE357511T1 (de) Dipeptidylpeptidasen
NO971684D0 (no) Nye benzoxazoler
DZ3147A1 (fr) Méthode de surveillance sismique d'une zone souterraine par utilisation simultanée de plusieurs sources vibrosismiques.
ATE244241T1 (de) Hemmung der menschlichen telomerase durch g- quadruplex interaktionverbindung
ATE384146T1 (de) Bauteil auf basis von gamma-tial-legierungen mit bereichen mit gradiertem gefüge
DE602004017486D1 (de) Substituierte heteroarylbenzofuransäuren
BRPI0413973A (pt) compostos
ATE294164T1 (de) Fluoreszenzfarbstoffe zum festphasen- und flüssigphasen-screening
DK0539435T3 (da) Fremgangsmåde til nedsættelse af interferenser ved en bestemmelse ved fluorescens
ATE317341T1 (de) Türrahmen für eine fahrzeugtür
DE60328513D1 (de) Induktion der mitochondrialen permeabilitätstransition
DE60113811D1 (de) NACHWEIS DER BINDUNG VON Ladungsträgern mittels PH- ODER POTENTiaL-SENSITIVEr SONDEN
FR2710074B1 (fr) Gène GRB3-3, ses variants et leurs utilisations.
FI980716A0 (fi) Arrangemang i samband med en hydraulvaetskedriven slaganordning, saosom t.ex. i en krossanordning
TR199800243T1 (xx) Prolil endopeptidaz inhibit�rleri.
DE60037723D1 (de) Verkleinerung der fluoreszenzlöschung während einer bestimmung
DE602004014630D1 (de) Imidazopyridinderivate als inhibitoren der induzierbaren no-synthase
ATE412894T1 (de) Fluorogene farbstoffe
DE602004014523D1 (de) Imidazoä4,5-büpyridinderivate als inhibitoren der induzierbaren no-synthase
ATE431425T1 (de) Schnelltest der antibiotika-empfindlichkeit

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties