ATE378595T1 - Beurteilungen und mittel auf populationsbasis zur bestimmung der rangfolge der relativen immunogenität von proteinen - Google Patents

Beurteilungen und mittel auf populationsbasis zur bestimmung der rangfolge der relativen immunogenität von proteinen

Info

Publication number
ATE378595T1
ATE378595T1 AT03719326T AT03719326T ATE378595T1 AT E378595 T1 ATE378595 T1 AT E378595T1 AT 03719326 T AT03719326 T AT 03719326T AT 03719326 T AT03719326 T AT 03719326T AT E378595 T1 ATE378595 T1 AT E378595T1
Authority
AT
Austria
Prior art keywords
proteins
present
provides means
ranking
population
Prior art date
Application number
AT03719326T
Other languages
English (en)
Inventor
Fiona Harding
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int filed Critical Genencor Int
Application granted granted Critical
Publication of ATE378595T1 publication Critical patent/ATE378595T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
AT03719326T 2002-02-26 2003-02-26 Beurteilungen und mittel auf populationsbasis zur bestimmung der rangfolge der relativen immunogenität von proteinen ATE378595T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36005702P 2002-02-26 2002-02-26

Publications (1)

Publication Number Publication Date
ATE378595T1 true ATE378595T1 (de) 2007-11-15

Family

ID=27766181

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03719326T ATE378595T1 (de) 2002-02-26 2003-02-26 Beurteilungen und mittel auf populationsbasis zur bestimmung der rangfolge der relativen immunogenität von proteinen

Country Status (13)

Country Link
US (1) US7879571B2 (de)
EP (1) EP1483581B1 (de)
JP (1) JP4430944B2 (de)
CN (3) CN1703511A (de)
AT (1) ATE378595T1 (de)
AU (1) AU2003223197A1 (de)
CA (1) CA2476790C (de)
DE (1) DE60317478T2 (de)
DK (1) DK1483581T3 (de)
IL (1) IL163139A (de)
MX (1) MXPA04007498A (de)
NZ (1) NZ534198A (de)
WO (1) WO2003073068A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1740952A2 (de) * 2004-04-26 2007-01-10 Genencor International, Inc. Populationsbasierte verfahren zur vorhersage für immunantwortbestimmungen und verfahren zur überprüfung der immunologischen antwortdaten
CN101151275B (zh) * 2005-04-27 2013-07-10 金克克国际有限公司 用于降低细胞因子免疫原性和去除细胞表面标记的方法
WO2007008951A1 (en) * 2005-07-12 2007-01-18 Codon Devices, Inc. Compositions and methods for design of non-immunogenic proteins
WO2007067473A2 (en) * 2005-12-06 2007-06-14 Genencor International, Inc. Perhydrolase epitopes
FR2940451B1 (fr) 2008-12-18 2014-09-12 Proteus Procede d'evaluation de l'immunogenicite des proteines
CN110846299B (zh) * 2019-11-22 2021-09-24 江南大学 一种前导肽突变体及其在角蛋白酶生产中的应用
CN114107266B (zh) * 2021-11-29 2023-11-14 青岛尚德生物技术有限公司 耐热性提高的蛋白酶突变体及其编码基因和应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261868A (en) 1979-08-08 1981-04-14 Lever Brothers Company Stabilized enzymatic liquid detergent composition containing a polyalkanolamine and a boron compound
US4404128A (en) 1981-05-29 1983-09-13 The Procter & Gamble Company Enzyme detergent composition
JPS58144105A (ja) 1982-02-12 1983-08-27 Kurabo Ind Ltd スケ−ル除去獣毛繊維の製法
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
US5204015A (en) 1984-05-29 1993-04-20 Genencor International, Inc. Subtilisin mutants
US5185258A (en) 1984-05-29 1993-02-09 Genencor International, Inc. Subtilisin mutants
WO1988004935A1 (en) 1986-12-31 1988-07-14 United States Of America, Represented By The Unite Method to predict antigenic sites recognized by t lymphocytes such as for design of vaccines
WO1989004552A1 (en) 1987-10-30 1989-05-18 Lsi Logic Corporation Method and means of fabricating a semiconductor device package
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
US5710126A (en) * 1993-03-12 1998-01-20 Immulogic Pharmaceutical Corporation T cell epitopes of ryegrass pollen allergen
US5691147A (en) * 1994-06-02 1997-11-25 Mitotix, Inc. CDK4 binding assay
US5627025A (en) * 1994-08-12 1997-05-06 The Rockefeller University Method for the identification of compounds capable of abrogating human immunodeficiency virus (HIV) infection of dendritic cells and T-lymphocytes
US5804201A (en) * 1996-03-11 1998-09-08 The Rockefeller University Immunomodulatory peptides of vespid antigen 5
US6110695A (en) 1997-12-02 2000-08-29 The Regents Of The University Of California Modulating the interaction of the chemokine, B Lymphocyte Hemoattractant, and its Receptor, BLR1
US6835550B1 (en) 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
US6451316B1 (en) 1998-10-05 2002-09-17 University Of Conneticut Health Center Methods for generating antigen-reactive T cells in vitro
US6861234B1 (en) * 2000-04-28 2005-03-01 Mannkind Corporation Method of epitope discovery

Also Published As

Publication number Publication date
JP2005518224A (ja) 2005-06-23
DK1483581T3 (da) 2008-03-17
NZ534198A (en) 2005-11-25
CA2476790A1 (en) 2003-09-04
CN1639571A (zh) 2005-07-13
AU2003223197A8 (en) 2003-09-09
MXPA04007498A (es) 2004-11-10
EP1483581A2 (de) 2004-12-08
AU2003223197A1 (en) 2003-09-09
EP1483581B1 (de) 2007-11-14
WO2003073068A2 (en) 2003-09-04
CN101575635A (zh) 2009-11-11
IL163139A (en) 2010-12-30
US7879571B2 (en) 2011-02-01
CN1703511A (zh) 2005-11-30
DE60317478D1 (de) 2007-12-27
US20050158806A1 (en) 2005-07-21
JP4430944B2 (ja) 2010-03-10
DE60317478T2 (de) 2008-09-04
CN1639571B (zh) 2010-05-26
WO2003073068A3 (en) 2003-12-11
CA2476790C (en) 2014-07-08
EP1483581A4 (de) 2005-08-10

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