ATE380191T1 - Gemischtes olanzapinsolvat, verfahren zu dessen herstellung und verfahren zur herstellung von olanzapin-form i daraus - Google Patents

Gemischtes olanzapinsolvat, verfahren zu dessen herstellung und verfahren zur herstellung von olanzapin-form i daraus

Info

Publication number
ATE380191T1
ATE380191T1 AT05759149T AT05759149T ATE380191T1 AT E380191 T1 ATE380191 T1 AT E380191T1 AT 05759149 T AT05759149 T AT 05759149T AT 05759149 T AT05759149 T AT 05759149T AT E380191 T1 ATE380191 T1 AT E380191T1
Authority
AT
Austria
Prior art keywords
olnzapine
solvate
therefrom
mixed
producing
Prior art date
Application number
AT05759149T
Other languages
English (en)
Inventor
Barjoan Pere Dalmases
Bellmunt Jordi Bessa
Original Assignee
Inke Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inke Sa filed Critical Inke Sa
Application granted granted Critical
Publication of ATE380191T1 publication Critical patent/ATE380191T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT05759149T 2004-07-27 2005-07-07 Gemischtes olanzapinsolvat, verfahren zu dessen herstellung und verfahren zur herstellung von olanzapin-form i daraus ATE380191T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200401850A ES2253091B1 (es) 2004-07-27 2004-07-27 Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.

Publications (1)

Publication Number Publication Date
ATE380191T1 true ATE380191T1 (de) 2007-12-15

Family

ID=35064845

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05759149T ATE380191T1 (de) 2004-07-27 2005-07-07 Gemischtes olanzapinsolvat, verfahren zu dessen herstellung und verfahren zur herstellung von olanzapin-form i daraus

Country Status (13)

Country Link
US (1) US7759484B2 (de)
EP (1) EP1773841B1 (de)
JP (1) JP2008508254A (de)
KR (1) KR20070063496A (de)
AR (1) AR050359A1 (de)
AT (1) ATE380191T1 (de)
DE (1) DE602005003678T2 (de)
ES (2) ES2253091B1 (de)
PL (1) PL1773841T3 (de)
PT (1) PT1773841E (de)
TW (1) TWI295993B (de)
WO (1) WO2006013435A1 (de)
ZA (1) ZA200700670B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7323459B2 (en) 2002-12-24 2008-01-29 Teva Pharmaceutical Industries Ltd. Crystal forms, methods for their preparation and method for preparation of olanzapine
EP1778649A4 (de) * 2004-07-14 2008-09-10 Jubilant Organosys Ltd Verfahren zur herstellung einer reinen form von 2-methyl-4-(4-methyl-1-piperazinyl)-10h-thieno[2,3-b][1,5]benzodiazepin
ES2292333B1 (es) * 2004-07-27 2008-12-16 Inke, S.A. Mejoras en el objeto de la patente principal n. 200401850, por "solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo".
ES2279715B1 (es) 2005-12-26 2008-06-01 Laboratorios Lesvi, S.L. Formulacion oral de olanzapina.
US8129522B2 (en) 2006-01-05 2012-03-06 Inke, S.A. Method for preparing a mixed solvate of olanzapine
CN102532158A (zh) * 2010-12-17 2012-07-04 北大方正集团有限公司 一种合成奥氮平的方法
JP6042153B2 (ja) * 2012-09-26 2016-12-14 株式会社トクヤマ オランザピンの製造方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
US5637584A (en) * 1995-03-24 1997-06-10 Eli Lilly And Company Solvate of olanzapine
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
EG24221A (en) * 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine
CR5278A (es) * 1995-03-24 1996-07-04 Lilly Co Eli Formulacion oral de 2-metil-tieno-benzodiacepina
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
ZA978515B (en) 1996-09-23 1999-03-23 Lilly Co Eli Intermediates and process for preparing olanzapine
AU752552C (en) * 1997-09-30 2003-09-11 Eli Lilly And Company 2-methyl-thieno-benzodiazepine formulation
AU759751B2 (en) * 1998-09-30 2003-05-01 Eli Lilly And Company 2-methyl-thieno-benzodiazepine formulation
CA2420987A1 (en) 2000-08-31 2002-03-07 Dr. Reddy's Laboratories Ltd. Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine
CH695862A5 (fr) 2001-12-24 2006-09-29 Sun Pharmaceutical Ind Ltd Forme cristalline I de la methyl-4-(4-methyl-1-piperazinyl) 10H-thieno [2,3-b] [1,5] benzodiazepine.
PL196814B1 (pl) * 2002-05-17 2008-02-29 Inst Farmaceutyczny Sposób wytwarzania odmiany polimorficznej I olanzapiny i jej solwaty
US7297789B2 (en) 2002-05-31 2007-11-20 Sandoz, Inc. Process of preparation of olanzapine form I
SI21270A (sl) * 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
US7323459B2 (en) * 2002-12-24 2008-01-29 Teva Pharmaceutical Industries Ltd. Crystal forms, methods for their preparation and method for preparation of olanzapine

Also Published As

Publication number Publication date
DE602005003678D1 (de) 2008-01-17
EP1773841B1 (de) 2007-12-05
EP1773841A1 (de) 2007-04-18
TW200613284A (en) 2006-05-01
ES2299049T3 (es) 2008-05-16
ES2253091A1 (es) 2006-05-16
JP2008508254A (ja) 2008-03-21
WO2006013435A1 (en) 2006-02-09
KR20070063496A (ko) 2007-06-19
ES2253091B1 (es) 2007-02-01
US7759484B2 (en) 2010-07-20
US20080280884A1 (en) 2008-11-13
AR050359A1 (es) 2006-10-18
PL1773841T3 (pl) 2008-04-30
ZA200700670B (en) 2008-08-27
DE602005003678T2 (de) 2008-11-20
TWI295993B (en) 2008-04-21
PT1773841E (pt) 2008-02-20

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties