ATE380342T1 - Peptidimmobilisierte grundplatte und vefahren zum testen eines zielproteins unter verwendung derselben - Google Patents

Peptidimmobilisierte grundplatte und vefahren zum testen eines zielproteins unter verwendung derselben

Info

Publication number
ATE380342T1
ATE380342T1 AT02724696T AT02724696T ATE380342T1 AT E380342 T1 ATE380342 T1 AT E380342T1 AT 02724696 T AT02724696 T AT 02724696T AT 02724696 T AT02724696 T AT 02724696T AT E380342 T1 ATE380342 T1 AT E380342T1
Authority
AT
Austria
Prior art keywords
target protein
peptide
protein
baseboard
immobilized
Prior art date
Application number
AT02724696T
Other languages
English (en)
Inventor
Kiyoshi Nokihara
Hisakazu Mihara
Original Assignee
Hipep Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hipep Lab filed Critical Hipep Lab
Application granted granted Critical
Publication of ATE380342T1 publication Critical patent/ATE380342T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT02724696T 2001-05-07 2002-05-07 Peptidimmobilisierte grundplatte und vefahren zum testen eines zielproteins unter verwendung derselben ATE380342T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001136606 2001-05-07
JP2002001759 2002-01-08

Publications (1)

Publication Number Publication Date
ATE380342T1 true ATE380342T1 (de) 2007-12-15

Family

ID=26614715

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02724696T ATE380342T1 (de) 2001-05-07 2002-05-07 Peptidimmobilisierte grundplatte und vefahren zum testen eines zielproteins unter verwendung derselben

Country Status (6)

Country Link
US (1) US8148141B2 (de)
EP (2) EP1403640B1 (de)
JP (2) JP4562018B2 (de)
AT (1) ATE380342T1 (de)
DE (1) DE60223922T2 (de)
WO (1) WO2002090985A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003106640A2 (en) 2002-06-14 2003-12-24 Case Western Reserve University Cell targeting methods and compositions
WO2004084950A2 (en) * 2003-03-24 2004-10-07 Case Western Reserve University Cell targeting methods and compositions
KR20080045705A (ko) * 2005-08-15 2008-05-23 테크니온 리서치 엔드 디벨로프먼트 화운데이션 엘티디. 인쇄가능 재료
US8865398B2 (en) 2006-09-01 2014-10-21 Abbott Laboratories Combination hepatitis C virus antigen and antibody detection method
JP5062524B2 (ja) * 2007-08-29 2012-10-31 株式会社ハイペップ研究所 固相基板表面上の官能基の定量方法
JP6059014B2 (ja) 2009-06-19 2017-01-11 アリゾナ ボード オブ リージェンツ ア ボディー コーポレート アクティング オン ビハーフ オブ アリゾナ ステイト ユニバーシティＡＲＩＺＯＮＡ ＢＯＡＲＤ ＯＦ ＲＥＧＥＮＴＳ，ａ ｂｏｄｙ ｃｏｒｐｏｒａｔｅ ａｃｔｉｎｇ ｏｎ ｂｅｈａｌｆ ｏｆ ＡＲＩＺＯＮＡ ＳＴＡＴＥ ＵＮＩＶＥＲＳＩＴＹ 試料の構成成分の検出において使用されるデバイスを製造する方法およびペプチドアレイ
TWI655213B (zh) 2012-07-13 2019-04-01 Menicon Co., Ltd. 自我組織化肽衍生物的製造方法
EP3087083B1 (de) 2013-12-27 2019-10-16 F.Hoffmann-La Roche Ag Systemische entdeckung, reifung und extension von peptidbindern zu proteinen
WO2016169894A1 (en) 2015-04-20 2016-10-27 F. Hoffmann-La Roche Ag Specific peptide binders to proteins identified via systemic discovery, maturation and extension process
US10758886B2 (en) 2015-09-14 2020-09-01 Arizona Board Of Regents On Behalf Of Arizona State University Conditioned surfaces for in situ molecular array synthesis
AU2017281039A1 (en) 2016-06-20 2019-01-24 Healthtell Inc. Methods for differential diagnosis of autoimmune diseases
WO2017223117A1 (en) 2016-06-20 2017-12-28 Healthtell Inc. Methods for diagnosis and treatment of autoimmune diseases
AU2017357818A1 (en) 2016-11-11 2019-05-30 HealthTell, Inc. Methods for identifying candidate biomarkers
US12025615B2 (en) 2017-09-15 2024-07-02 Arizona Board Of Regents On Behalf Of Arizona State University Methods of classifying response to immunotherapy for cancer
WO2021067550A1 (en) 2019-10-02 2021-04-08 Arizona Board Of Regents On Behalf Of Arizona State University Methods and compositions for identifying neoantigens for use in treating and preventing cancer
CN114195857B (zh) * 2021-10-14 2023-07-04 中国科学院海洋研究所 一种降压肽及其制备方法和应用
CN115572319B (zh) * 2022-06-27 2025-12-19 欧诗漫生物股份有限公司 珍珠美白抗衰组合多肽和单一美白多肽的制备方法和应用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE446866B (sv) * 1977-11-15 1986-10-13 Sloan Kettering Inst Cancer Sett att framstella en aktiv polypeptid med formaga att inducera differentiering av bade t-lymfocyter och komplementreceptor (cr?72+) b-lymfocyter
US4507230A (en) * 1982-05-12 1985-03-26 Research Corporation Peptide synthesis reagents and method of use
US5591646A (en) * 1992-09-02 1997-01-07 Arris Pharmaceutical Method and apparatus for peptide synthesis and screening
US5605809A (en) * 1994-10-28 1997-02-25 Oncoimmunin, Inc. Compositions for the detection of proteases in biological samples and methods of use thereof
US6165335A (en) * 1996-04-25 2000-12-26 Pence And Mcgill University Biosensor device and method
JPH1025299A (ja) 1996-07-12 1998-01-27 Nec Corp 整列ペプチド、及びそれを用いたタンパク質の結合・相互作用部位検出方法
CA2267200A1 (en) * 1996-10-07 1998-04-16 Schering Corporation Assay for the detection of antibodies against p53
US5998204A (en) * 1997-03-14 1999-12-07 The Regents Of The University Of California Fluorescent protein sensors for detection of analytes
US6376257B1 (en) 1997-04-24 2002-04-23 University Of Rochester Detection by fret changes of ligand binding by GFP fusion proteins
JPH10319017A (ja) * 1997-05-20 1998-12-04 Toyobo Co Ltd 蛍光エネルギー転移を利用した物質の測定方法およびそのための試薬
US6927025B1 (en) * 1997-09-03 2005-08-09 Biovation Limited Methods for protein screening
US6197599B1 (en) * 1998-07-30 2001-03-06 Guorong Chin Method to detect proteins
US7018846B1 (en) 1998-08-10 2006-03-28 Science & Technology Corporation @ Unm Display of receptors and analysis of binding interactions and drug libraries
WO2000034521A1 (en) * 1998-12-08 2000-06-15 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
CA2371816C (en) * 1999-02-18 2010-04-27 The Regents Of The University Of California Phthalamide-lanthanide complexes for use as luminescent markers
GB9904395D0 (en) 1999-02-25 1999-04-21 Fluorescience Ltd Protein assay
CA2365431A1 (en) 1999-03-10 2000-09-14 Hui Ge Universal protein array system
US6284465B1 (en) * 1999-04-15 2001-09-04 Agilent Technologies, Inc. Apparatus, systems and method for locating nucleic acids bound to surfaces
US6692916B2 (en) * 1999-06-28 2004-02-17 Source Precision Medicine, Inc. Systems and methods for characterizing a biological condition or agent using precision gene expression profiles
GB9923146D0 (en) * 1999-09-30 1999-12-01 Imperial College Detector array
WO2001064831A1 (en) * 2000-02-29 2001-09-07 The Board Of Trustees Of The Leland Stanford Junior University Microarray substrate with integrated photodetector and methods of use thereof
JP2001242116A (ja) * 2000-03-02 2001-09-07 Fuji Photo Film Co Ltd タンパクチップおよびタンパク質の検出方法
JP3643520B2 (ja) * 2000-07-04 2005-04-27 独立行政法人科学技術振興機構 ｃＧＭＰ可視化プローブ及びそれを利用したｃＧＭＰの検出・定量方法
DE60131468D1 (de) * 2000-09-25 2007-12-27 U S Medical Res Inst Of Infect Hoch-durchsatz assays für proteolytische aktivitäten von clostridium neurotoxinen

Also Published As

Publication number Publication date
JP4912362B2 (ja) 2012-04-11
US20050084902A1 (en) 2005-04-21
EP1403640A1 (de) 2004-03-31
DE60223922D1 (de) 2008-01-17
WO2002090985A1 (en) 2002-11-14
JP4562018B2 (ja) 2010-10-13
US8148141B2 (en) 2012-04-03
EP1403640A4 (de) 2004-06-30
EP1403640B1 (de) 2007-12-05
EP1914550A1 (de) 2008-04-23
DE60223922T2 (de) 2008-11-27
JPWO2002090985A1 (ja) 2004-08-26
JP2008268231A (ja) 2008-11-06

Similar Documents

Publication Publication Date Title
ATE380342T1 (de) Peptidimmobilisierte grundplatte und vefahren zum testen eines zielproteins unter verwendung derselben
US7011940B1 (en) Quality control for cytochemical assays
Haab Antibody arrays in cancer research
US6197599B1 (en) Method to detect proteins
DE69938623D1 (de) Microarrays und ihre verwendungen
JP5707421B2 (ja) 合成基材及び細胞基材に結合した抗体の同時検出による疾病診断のための方法及びシステム
DE60307645D1 (de) Hoch-durchsatz assay zur messung von zellulären antworten mit hilfe von mikroarrays
WO2003078962A3 (en) Detection and quantification of modified proteins
CN100420947C (zh) 用单一捕获剂定量检测特异性分析物的方法及其试剂盒
WO2006126008A3 (en) Improved immunoassay methods
ATE364839T1 (de) Ein für die messung einer änderung der dicke oder masse an seiner oberfläche geeignetes affinitätsprobenarray
WO2003066906A3 (en) Diagnostic microarray and method of use thereof
DE60134957D1 (de) Methoden und testsätze für annäherungstest
KR20120129947A (ko) 연장된 동적 범위를 갖는 어레이 및 관련 방법
WO2000062064A2 (en) Quality control for cytochemical assays
WO2006055739A3 (en) Stationary phase antibody arrays for trace protein analysis
CA2235316A1 (en) A method for detecting antipolymer antibodies and a diagnostic test kit for use in aiding the diagnosis of silicone related diseases (srd)
WO2006113245B1 (en) Methods for measuring glycan levels of proteins
Joos et al. Protein microarrays: potentials and limitations
CN106513062B (zh) 酶联免疫快速检测的微流控芯片及其预处理和检测方法
US20070141723A1 (en) Immunohistochemistry staining controls
Tapia et al. Affinity profiling using the peptide microarray technology: a case study
DK1360491T3 (da) Biokemisk fremgangsmåde og apparat til detektion af proteinegenskaber
WO2004081025A3 (en) Differential megaplex immunoassay
CA2366651A1 (en) A method for detecting megsin protein and use thereof

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties