ATE380785T1 - Herstellung eines neolignans mittels durch ddq vermittelte dimerisierung von dihydroasaron - Google Patents
Herstellung eines neolignans mittels durch ddq vermittelte dimerisierung von dihydroasaronInfo
- Publication number
- ATE380785T1 ATE380785T1 AT02713168T AT02713168T ATE380785T1 AT E380785 T1 ATE380785 T1 AT E380785T1 AT 02713168 T AT02713168 T AT 02713168T AT 02713168 T AT02713168 T AT 02713168T AT E380785 T1 ATE380785 T1 AT E380785T1
- Authority
- AT
- Austria
- Prior art keywords
- neolignan
- ddq
- preparation
- asarone
- dihydroasarone
- Prior art date
Links
- 229930182783 neolignan Natural products 0.000 title abstract 3
- SNDHRSZUZCBJPB-UHFFFAOYSA-N 1,2,4-trimethoxy-5-propylbenzene Chemical compound CCCC1=CC(OC)=C(OC)C=C1OC SNDHRSZUZCBJPB-UHFFFAOYSA-N 0.000 title 1
- 238000006471 dimerization reaction Methods 0.000 title 1
- RKFAZBXYICVSKP-AATRIKPKSA-N alpha-asarone Chemical compound COC1=CC(OC)=C(\C=C\C)C=C1OC RKFAZBXYICVSKP-AATRIKPKSA-N 0.000 abstract 4
- AUNAUZZQBAIQFJ-UHFFFAOYSA-N 2,4,5-Trimethoxy-1-allylbenzene Chemical compound COC1=CC(OC)=C(OC)C=C1CC=C AUNAUZZQBAIQFJ-UHFFFAOYSA-N 0.000 abstract 2
- RKFAZBXYICVSKP-UHFFFAOYSA-N beta- asarone Natural products COC1=CC(OC)=C(C=CC)C=C1OC RKFAZBXYICVSKP-UHFFFAOYSA-N 0.000 abstract 2
- RKFAZBXYICVSKP-WAYWQWQTSA-N beta-asarone Chemical compound COC1=CC(OC)=C(\C=C/C)C=C1OC RKFAZBXYICVSKP-WAYWQWQTSA-N 0.000 abstract 2
- RBWARIDRNSFBTH-UHFFFAOYSA-N 1-(2,4,5-trimethoxyphenyl)pentan-3-one Chemical compound CCC(=O)CCC1=CC(OC)=C(OC)C=C1OC RBWARIDRNSFBTH-UHFFFAOYSA-N 0.000 abstract 1
- 244000205574 Acorus calamus Species 0.000 abstract 1
- 235000006480 Acorus calamus Nutrition 0.000 abstract 1
- 239000010629 calamus oil Substances 0.000 abstract 1
- 230000000447 dimerizing effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
- C07C43/2055—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring containing more than one ether bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2002/000073 WO2003080551A1 (en) | 2002-03-27 | 2002-03-27 | Formation of neolignan by ddq mediated dimerisation of dihydroasarone |
| US10/108,269 US20030187306A1 (en) | 2002-03-27 | 2002-03-28 | DDQ mediated one step dimerisation of beta-asarone or beta-asarone rich acorus calamus oil in the formation of novel neolignan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE380785T1 true ATE380785T1 (de) | 2007-12-15 |
Family
ID=30002057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02713168T ATE380785T1 (de) | 2002-03-27 | 2002-03-27 | Herstellung eines neolignans mittels durch ddq vermittelte dimerisierung von dihydroasaron |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20030187306A1 (de) |
| EP (1) | EP1487770B1 (de) |
| JP (1) | JP4266348B2 (de) |
| AT (1) | ATE380785T1 (de) |
| AU (1) | AU2002244906A1 (de) |
| DE (1) | DE60224098T2 (de) |
| WO (1) | WO2003080551A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1577289A1 (de) * | 2004-03-18 | 2005-09-21 | Revotar Biopharmaceuticals AG | Nicht-glykosylierte/-glykosidische/-peptidische keine Moleküle als Selektininhibitoren für die Behandlung entzündlicher Erkrankungen. |
| EP1764094A1 (de) * | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Neuartige multi-zyklische Verbindungen und deren Verwendung |
| EP1764095A1 (de) * | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Neue Nitrocatecholderivate mit Selectin-Ligand-Activität |
| EP1764093A1 (de) * | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Neue aromatische Verbindungen und deren medizinische Verwendung |
| EP1764096A1 (de) * | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Neue Phloroglucinolderivate mit Selectin-Ligand-Aktivität |
| EP1935919B1 (de) | 2005-10-13 | 2012-09-05 | Yamamoto Chemicals, Inc. | Polymer mit sulfogruppen und das polymer enthaltendes organisches elektrolumineszenzelement |
| US8049326B2 (en) * | 2007-06-07 | 2011-11-01 | The Regents Of The University Of Michigan | Environment-resistant module, micropackage and methods of manufacturing same |
| US7872160B2 (en) * | 2008-03-31 | 2011-01-18 | Council Of Scientific & Industrial Research | Single pot process for the regioselective synthesis of neolignan framework asarones |
| JP5673030B2 (ja) * | 2010-11-29 | 2015-02-18 | ユーハ味覚糖株式会社 | 新規フェノール性2量体化合物 |
| JP5673026B2 (ja) * | 2010-11-26 | 2015-02-18 | ユーハ味覚糖株式会社 | 4−ビニルグアイアコール重合化合物又はその薬学的に許容可能な塩を含む抗癌剤、食品、医薬品 |
| CN102126933B (zh) * | 2010-12-20 | 2013-03-20 | 湖南大学 | 一种二苯基丙烷类木脂素化合物及其制备方法 |
| CN106860437B (zh) * | 2017-02-21 | 2019-08-02 | 南方医科大学 | 双细辛酮i作为治疗登革病毒感染的药物及其制药用途 |
| CN116554397B (zh) * | 2023-05-18 | 2025-04-22 | 深圳市德泰能源有限公司 | 一种锂电池负极粘结剂及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3769350A (en) | 1968-12-09 | 1973-10-30 | Hoffmann La Roche | Method for making 2,3-dimethyl-1,4-bis(3,4 - hydrocarbonyloxyphenyl) - 1,4-butanedione |
| US4540709A (en) | 1983-10-13 | 1985-09-10 | Merck & Co., Inc. | Method for treatment of diseases mediated by PAF using 5-allyl-2-(3,4-Dimethoxyphenyl)-3a,α-methoxy-3-methyl-2,3,3a,6-tetrahydro-6-oxobenzofuran |
| FR2595350B1 (fr) | 1986-03-06 | 1988-11-10 | Maine Universite | Procede de couplage biarylique, catalyseur au ruthenium pour sa mise en oeuvre et nouveaux composes en resultant |
| US5639782A (en) | 1992-03-04 | 1997-06-17 | Center For Innovative Technology | Neolignan derivatives as platelet activating factor receptor antagonists and 5-lipoxygenase inhibitors |
| US6136992A (en) | 1997-03-13 | 2000-10-24 | The United States Of America As Represented By The Department Of Health And Human Services | 2-alkoxy estradiols and derivatives thereof |
| US6590127B1 (en) * | 2002-03-28 | 2003-07-08 | Council Of Scientific & Industrial Research | Process for the preparation of pharmacologically active α-asarone from toxic β-asarone rich acorus calamus oil |
-
2002
- 2002-03-27 JP JP2003580930A patent/JP4266348B2/ja not_active Expired - Fee Related
- 2002-03-27 EP EP02713168A patent/EP1487770B1/de not_active Expired - Lifetime
- 2002-03-27 WO PCT/IN2002/000073 patent/WO2003080551A1/en not_active Ceased
- 2002-03-27 AT AT02713168T patent/ATE380785T1/de not_active IP Right Cessation
- 2002-03-27 AU AU2002244906A patent/AU2002244906A1/en not_active Abandoned
- 2002-03-27 DE DE60224098T patent/DE60224098T2/de not_active Expired - Lifetime
- 2002-03-28 US US10/108,269 patent/US20030187306A1/en not_active Abandoned
-
2003
- 2003-09-12 US US10/660,556 patent/US6969778B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1487770B1 (de) | 2007-12-12 |
| WO2003080551A1 (en) | 2003-10-02 |
| EP1487770A1 (de) | 2004-12-22 |
| AU2002244906A1 (en) | 2003-10-08 |
| DE60224098D1 (de) | 2008-01-24 |
| JP2005521734A (ja) | 2005-07-21 |
| DE60224098T2 (de) | 2008-12-04 |
| JP4266348B2 (ja) | 2009-05-20 |
| US20040049085A1 (en) | 2004-03-11 |
| US6969778B2 (en) | 2005-11-29 |
| US20030187306A1 (en) | 2003-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |