ATE381345T1 - Alpha-emittierende konstrukte sowie deren verwendung - Google Patents

Alpha-emittierende konstrukte sowie deren verwendung

Info

Publication number
ATE381345T1
ATE381345T1 AT99940789T AT99940789T ATE381345T1 AT E381345 T1 ATE381345 T1 AT E381345T1 AT 99940789 T AT99940789 T AT 99940789T AT 99940789 T AT99940789 T AT 99940789T AT E381345 T1 ATE381345 T1 AT E381345T1
Authority
AT
Austria
Prior art keywords
cells
alpha
constructs
emitting
emitting constructs
Prior art date
Application number
AT99940789T
Other languages
English (en)
Inventor
David Scheinberg
Dangshe Ma
Michael Mcdevitt
George Sgouros
Original Assignee
Sloan Kettering Inst Cancer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sloan Kettering Inst Cancer filed Critical Sloan Kettering Inst Cancer
Application granted granted Critical
Publication of ATE381345T1 publication Critical patent/ATE381345T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Revetment (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT99940789T 1998-05-26 1999-05-26 Alpha-emittierende konstrukte sowie deren verwendung ATE381345T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8677298P 1998-05-26 1998-05-26

Publications (1)

Publication Number Publication Date
ATE381345T1 true ATE381345T1 (de) 2008-01-15

Family

ID=22200805

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99940789T ATE381345T1 (de) 1998-05-26 1999-05-26 Alpha-emittierende konstrukte sowie deren verwendung

Country Status (7)

Country Link
EP (1) EP1091757B1 (de)
JP (1) JP5064608B2 (de)
AT (1) ATE381345T1 (de)
CA (1) CA2333125C (de)
DE (1) DE69937797D1 (de)
ES (1) ES2299256T3 (de)
WO (1) WO1999061097A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO312708B1 (no) * 2000-02-21 2002-06-24 Anticancer Therapeutic Inv Sa Radioaktive liposomer til terapi
EP2326350B1 (de) 2008-09-08 2013-09-04 Psma Development Company, L.L.C. Verbindungen zur tötung von psma-expriemierenden und taxane-resistenten krebszellen
CN104710504B (zh) * 2009-07-22 2019-09-13 锕医药股份有限公司 用于制备放射性免疫缀合物的方法
WO2022087416A1 (en) * 2020-10-22 2022-04-28 Actinium Pharmaceuticals, Inc. Combination radioimmunotherapy and cd47 blockade in the treatment of cancer
WO2023114255A1 (en) * 2021-12-14 2023-06-22 Boston Scientific Scimed Inc. Radioactive shear thinning biomaterial composition and methods for use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0282057A3 (de) * 1987-03-11 1990-03-07 The Board Of Regents Of The University Of Michigan Chemo-Radio-Immunkonjugate
EP0504327B1 (de) * 1989-12-14 2000-09-20 Sloan-Kettering Institute For Cancer Research Therapeutische verwendungen der hypervariablen region des monoklonalen antikörpers m195 und konstrukte davon
PT627940E (pt) * 1992-03-05 2003-07-31 Univ Texas Utilizacao de imunoconjugados para o diagnostico e/ou terapia de tumores vascularizados
CA2100709C (en) * 1992-07-27 2004-03-16 Maurits W. Geerlings Method and means for site directed therapy

Also Published As

Publication number Publication date
JP5064608B2 (ja) 2012-10-31
JP2002516297A (ja) 2002-06-04
EP1091757A4 (de) 2002-08-07
EP1091757B1 (de) 2007-12-19
WO1999061097A3 (en) 2000-02-03
WO1999061097A9 (en) 2000-06-02
CA2333125C (en) 2009-12-15
ES2299256T3 (es) 2008-05-16
EP1091757A2 (de) 2001-04-18
CA2333125A1 (en) 1999-12-02
DE69937797D1 (de) 2008-01-31
WO1999061097A2 (en) 1999-12-02

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