ATE381572T1 - Synthese von spongosin - Google Patents

Synthese von spongosin

Info

Publication number: ATE381572T1
Authority: AT; Austria
Prior art keywords: synthesis; spongosine; methoxyadenine; benzoyl; tri
Prior art date: 2004-01-21

Application number

AT05701948T

Other languages

English (en)

Inventor

Jacqueline Ouzman

Original Assignee

Cambridge Biotechnology Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-01-21

Filing date

2005-01-19

Publication date

2008-01-15

2005-01-19 Application filed by Cambridge Biotechnology Ltd filed Critical Cambridge Biotechnology Ltd

2008-01-15 Application granted granted Critical

2008-01-15 Publication of ATE381572T1 publication Critical patent/ATE381572T1/de

Links

AJACDNCVEGIBNA-KQYNXXCUSA-N (2r,3r,4s,5r)-2-(6-amino-2-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol Chemical compound C12=NC(OC)=NC(N)=C2N=CN1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O AJACDNCVEGIBNA-KQYNXXCUSA-N 0.000 title abstract 3
AJACDNCVEGIBNA-UHFFFAOYSA-N 2-Methoxyadenosine Natural products C12=NC(OC)=NC(N)=C2N=CN1C1OC(CO)C(O)C1O AJACDNCVEGIBNA-UHFFFAOYSA-N 0.000 title abstract 3
230000015572 biosynthetic process Effects 0.000 title abstract 3
238000003786 synthesis reaction Methods 0.000 title abstract 3
NZRGFQAPUIYXEP-ZYWWQZICSA-N [(2r,3r,4r,5r)-5-(6-amino-2-methoxypurin-9-yl)-3,4-dibenzoyloxyoxolan-2-yl]methyl benzoate Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H]1OC(=O)C=1C=CC=CC=1)OC(=O)C=1C=CC=CC=1)N1C=NC2=C(N)N=C(N=C21)OC)OC(=O)C1=CC=CC=C1 NZRGFQAPUIYXEP-ZYWWQZICSA-N 0.000 abstract 2
TUDKBZAMOFJOSO-UHFFFAOYSA-N 2-methoxy-7h-purin-6-amine Chemical compound COC1=NC(N)=C2NC=NC2=N1 TUDKBZAMOFJOSO-UHFFFAOYSA-N 0.000 abstract 1
GCZABPLTDYVJMP-CBUXHAPBSA-N [(2r,3r,4r,5s)-5-acetyloxy-3,4-dibenzoyloxyoxolan-2-yl]methyl benzoate Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H]1OC(=O)C=1C=CC=CC=1)OC(=O)C=1C=CC=CC=1)OC(=O)C)OC(=O)C1=CC=CC=C1 GCZABPLTDYVJMP-CBUXHAPBSA-N 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
238000010511 deprotection reaction Methods 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Saccharide Compounds (AREA)
Silicon Polymers (AREA)
Catalysts (AREA)

AT05701948T 2004-01-21 2005-01-19 Synthese von spongosin ATE381572T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0401292.8A GB0401292D0 (en)	2004-01-21	2004-01-21	Synthesis of spongosine

Publications (1)

Publication Number	Publication Date
ATE381572T1 true ATE381572T1 (de)	2008-01-15

Family

ID=31971211

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05701948T ATE381572T1 (de)	2004-01-21	2005-01-19	Synthese von spongosin

Country Status (18)

Country	Link
US (1)	US20100216991A1 (de)
EP (1)	EP1709057B1 (de)
JP (1)	JP2007518782A (de)
KR (1)	KR20060132910A (de)
CN (1)	CN1910194B (de)
AT (1)	ATE381572T1 (de)
AU (1)	AU2005206361A1 (de)
CA (1)	CA2552552A1 (de)
CY (1)	CY1108048T1 (de)
DE (1)	DE602005003922T2 (de)
DK (1)	DK1709057T3 (de)
ES (1)	ES2298998T3 (de)
GB (1)	GB0401292D0 (de)
NO (1)	NO20063715L (de)
NZ (1)	NZ548220A (de)
PL (1)	PL1709057T3 (de)
PT (1)	PT1709057E (de)
WO (1)	WO2005070947A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20080221060A1 (en) *	2004-03-05	2008-09-11	Martyn Pritchard	Therapeutic Compounds
WO2014068589A2 (en) *	2012-10-29	2014-05-08	Biophore India Pharmaceuticals Pvt. Ltd.	Novel process for the preparation of (1-{9-[(4s, 2r, 3r, 5r)-3, 4-dihydroxy-5-(hydroxymethyl) oxolan-2-yl)-6-aminopurin-2-yl} pyrazole-4-yl)-n-methylcarboxamide
CN103342727A (zh) *	2013-07-01	2013-10-09	淮海工学院	一种2-甲氧基腺苷的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030008841A1 (en) *	2000-08-30	2003-01-09	Rene Devos	Anti-HCV nucleoside derivatives

2004
- 2004-01-21 GB GBGB0401292.8A patent/GB0401292D0/en not_active Ceased
2005
- 2005-01-19 ES ES05701948T patent/ES2298998T3/es not_active Expired - Lifetime
- 2005-01-19 NZ NZ548220A patent/NZ548220A/en unknown
- 2005-01-19 CN CN200580003003XA patent/CN1910194B/zh not_active Expired - Fee Related
- 2005-01-19 DK DK05701948T patent/DK1709057T3/da active
- 2005-01-19 AT AT05701948T patent/ATE381572T1/de active
- 2005-01-19 JP JP2006550274A patent/JP2007518782A/ja active Pending
- 2005-01-19 WO PCT/GB2005/000183 patent/WO2005070947A1/en not_active Ceased
- 2005-01-19 PT PT05701948T patent/PT1709057E/pt unknown
- 2005-01-19 CA CA002552552A patent/CA2552552A1/en not_active Abandoned
- 2005-01-19 AU AU2005206361A patent/AU2005206361A1/en not_active Abandoned
- 2005-01-19 US US10/586,558 patent/US20100216991A1/en not_active Abandoned
- 2005-01-19 DE DE602005003922T patent/DE602005003922T2/de not_active Expired - Lifetime
- 2005-01-19 PL PL05701948T patent/PL1709057T3/pl unknown
- 2005-01-19 KR KR1020067016484A patent/KR20060132910A/ko not_active Ceased
- 2005-01-19 EP EP05701948A patent/EP1709057B1/de not_active Expired - Lifetime
2006
- 2006-08-18 NO NO20063715A patent/NO20063715L/no not_active Application Discontinuation
2008
- 2008-03-07 CY CY20081100268T patent/CY1108048T1/el unknown

Also Published As

Publication number	Publication date
EP1709057A1 (de)	2006-10-11
WO2005070947A1 (en)	2005-08-04
CA2552552A1 (en)	2005-08-04
GB0401292D0 (en)	2004-02-25
JP2007518782A (ja)	2007-07-12
CN1910194A (zh)	2007-02-07
NZ548220A (en)	2009-12-24
HK1099026A1 (zh)	2007-08-03
PL1709057T3 (pl)	2008-05-30
DE602005003922T2 (de)	2008-12-04
DK1709057T3 (da)	2008-04-28
EP1709057B1 (de)	2007-12-19
NO20063715L (no)	2006-08-18
DE602005003922D1 (de)	2008-01-31
AU2005206361A1 (en)	2005-08-04
PT1709057E (pt)	2008-03-10
KR20060132910A (ko)	2006-12-22
ES2298998T3 (es)	2008-05-16
US20100216991A1 (en)	2010-08-26
CN1910194B (zh)	2010-05-05
CY1108048T1 (el)	2013-09-04

Similar Documents

Publication	Publication Date	Title
PE20081653A1 (es)	2008-11-04	Uso de moleculas de union especifica al antigeno cd20 en dosis unica
ATE524476T1 (de)	2011-09-15	Pyrazolopyrimidine als modulatoren von caseinkinase ii (ck2)
SE0301653D0 (sv)	2003-06-05	Novel compounds
ECSP056111A (es)	2006-03-01	Derivados de 2-acilamino-4-feniltiazol, su preparación y aplicación en terapeutica
GT200500363A (es)	2006-11-27	3-amino-pirazol [3,4b] piridinas con inhibidores de proteintirosinquinasas, su preparacion y uso como medicamento.
EP1732602A4 (de)	2008-05-07	Zytotoxizitätsvermittlung von zellen mit hinweisen auf oberflächenexpression von mcsp
CR7583A (es)	2008-08-21	Nueva sal formiato de o-desmetil venlafaxina
NO20082240L (no)	2008-07-22	GLP-2 imitatorstoff, polypeptider, sammensetninger, fremgangsmater og anvendelser
DE602004030334D1 (de)	2011-01-13	Synthese von 5-substituierten 7-azaindolen und 7-azaindolinen
EA200801427A1 (ru)	2008-12-30	Молекулы антитела со специфической активностью в отношении интерлейкина-6 (ил-6) человека
TW200608960A (en)	2006-03-16	3-aminocyclopentanecarboxamides as modulators of chemokine receptors
EA200700717A1 (ru)	2007-10-26	Сульфонамиды
TW200608966A (en)	2006-03-16	3-aminocyclopentanecarboxamides as modulators of chemokine receptors
CO5660287A2 (es)	2006-07-31	Derivados de tetrahidrocarbazol y su uso farmaceutico
CY1108156T1 (el)	2014-02-12	Στερεοεκλεκτικη συνθεση αναλογων βιταμινης d
DE602006009789D1 (de)	2009-11-26	Acetylenderivate
CY1108048T1 (el)	2013-09-04	Συνθεση σπογγοσινης
EA200701172A1 (ru)	2007-10-26	2-алкокси-3,4,5-тригидроксиалкиламиды, их получение, композиции, их содержащие, и применение
HRP20090513T1 (hr)	2009-10-31	S-mirtazapin, namijenjen liječenju napadaja vrućine
DE602006021327D1 (de)	2011-05-26	Isochinoline als igf-1r-inhibitoren
EA200700550A1 (ru)	2007-10-26	Производные алкилидентетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств
TW200745133A (en)	2007-12-16	New compounds II
TW200616624A (en)	2006-06-01	2-substituted-1-deaza purine derivatives with adenosine receptor modulating activity
ATE502007T1 (de)	2011-04-15	Synthese von optisch reinem (r)-5-(2-aminopropyl)-2-methoxybenzolsulphonami
EA200600573A1 (ru)	2006-08-25	Активаторы плазминогена, имеющие сниженную способность связывать лизин

Legal Events

Date

Code

Title

Description

2008-07-15

UEP

Publication of translation of european patent specification

Ref document number: 1709057

Country of ref document: EP